Bruno Fernandes has tested positive for COVID-19 and could miss Manchester United's crucial Champions League home clash with Atletico Madrid.
The playmaker missed Saturday's 3-2 win over Tottenham at Old Trafford, with his absence put down to an undisclosed illness.
Details have now emerged from interim manager Ralf Rangnick, who said Fernandes faced a race against time to be ready for the last-16 second leg on Tuesday.
Luke Shaw could be back from a coronavirus lay-off, while Rangnick is hopeful midfielder Scott McTominay will be able to feature after a calf problem.
Speaking of Fernandes, Rangnick said: "I don't know. With Scotty, I hope so, but he had some muscular problems with his calf. That's why we decided not to play him [against Tottenham], because Scotty, quite like Fred, is only valuable if he can perform with 100 per cent of his physical capacity.
"Luke hopefully will be back in training Monday and Bruno we will have to wait and see until Tuesday. This will probably be a last-minute race with him – due to COVID."
Fernandes has been United's chief creative force in the Champions League this season, with his six assists putting him four ahead of Shaw, who is second on that list at the club. He has also created a team-high 20 chances in the competition, with Cristiano Ronaldo next with nine.
Ronaldo's hat-trick against Tottenham has raised hopes that he can make a telling difference in Europe, too, with United level at 1-1 with Atletico after the first leg in Spain.
Rangnick said of his 37-year-old superstar striker: "He can be a leader with a performance like that. This is what I have been telling him since I arrived, that with this kind of performance he can be one of the engines of the team.
"We have quite a few other players who can do the same, including Fred, Harry [Maguire], Rapha [Raphael Varane], Victor [Lindelof], whoever. Even Edi [Edinson Cavani], when he came on, the last 10 or 15 minutes showed how important and what kind of role he can still play. I wish him to be available until the end of the season."
Rangnick was pleased with Jadon Sancho against Tottenham, with a notable assist for Ronaldo's second goal reflecting the winger's growing influence.
Sancho arrived with a big reputation from Borussia Dortmund last year and the 21-year-old did not immediately make the expected impact, but he is beginning to catch the eye.
"This is what he should be," said Rangnick, quoted on United's official website. "The club paid quite a few pounds for him in order to lure him away from Borussia Dortmund and if you pay that amount of money in a transfer fee for a player, he should perform on this kind of level.
"At the end, they are all human beings. The mere fact he cost a lot of money does not mean that he is playing at that level to start with.
"He told me that of course it was a problem for him to get adjusted to the intensity of the league, to the physicality of the league. Now he has managed to do that. I'm happy to see him play at that kind of level right now."
Sancho given fresh start with Chelsea loan move
Jadon Sancho has secured a move away from Manchester United, having joined Chelsea on Deadline Day on a season-long loan.
The deal includes an obligation to buy for between £20-£25 million at the end of the loan, according to widespread reports, meaning that the 24-year-old will not be returning to Old Trafford next summer.
Work to complete the transfer came late on Deadline Day, with a deal sheet being submitted to ensure the signing could go through after the 11pm deadline.
Chelsea were able to get the deal over the line, confirming the move was complete on Saturday evening.
"I’m really excited to be here," Sancho said. "London is where I grew up and I’m happy to be back.
"The manager spoke to me about the project and, for a young player, it's exciting. Hopefully I can bring goals and assists to the Bridge."
It brings an end to a three-year spell at Old Trafford for Sancho. The winger originally joined United on a five-year contract in 2021 but, following a public falling out with manager Erik ten Hag, found his first-team opportunities limited.
Sancho made 83 appearances in all competitions for United, but his last start for the club came against Manchester City in the 2023 FA Cup final. He made three substitute appearances in August 2023 before moving back to Dortmund on loan in January, where he scored three goals in 21 appearances.
His final outing in a United shirt came off the bench in their Community Shield defeat to Manchester City, but he was not included in the squad for the first two league games.
Sancho joins a club with plenty of competition for attacking places, with Cole Palmer, Christopher Nkunku, Nicolas Jackson, Pedro Neto, Joao Felix and Noni Madueke among their roster.
Chelsea did also manage to move some players on during Deadline Day. Raheem Sterling secured a loan move to Arsenal on Deadline Day, while Trevoh Chalobah joined Crystal Palace, Armando Broja moved to Everton and Djordje Petrovic was loaned by Strasbourg.
Brentford 3-1 Southampton: Bees begin life after Toney with comfortable win
Brentford began life without Ivan Toney with a comfortable 3-1 victory over Southampton.
Bryan Mbeumo’s brace and a Yoane Wissa goal proved to be the difference between the two sides and condemned the Saints to their third straight loss since promotion back to the Premier League.
With departed striker Toney watching in the stands after his move to Al-Ahli in Saudi Arabia, the hosts proved too strong for Russell Martin’s men. They created the superior chances and capitalised on an error-strewn performance from Southampton’s backline.
Mbeumo opened the scoring on the stroke of half-time before doubling the lead halfway through the second period and Wissa then got on the scoresheet moments later to continue Brentford’s strong start to the campaign. Yukinari Sugawara bagged a consolation in injury time for the Saints.
Brentford sit in fifth place ahead of the first international break, while Southampton are second-bottom of the league table with zero points.
Data debrief: Wissa continues to prove effective at home
Wissa now has five goals and two assists in his last seven matches at the Gtech Community Stadium.
Brentford have recorded consecutive home league wins for the first time since last November, and the first time in their opening home games since August 2018.
Brentford 3-1 Southampton: Bees begin life without Toney with comfortable win
Brentford began life without Ivan Toney with a comfortable 3-1 victory over Southampton.
Bryan Mbeumo’s brace and a Yoane Wissa goal proved to be the difference between the two sides and condemned the Saints to their third straight loss since promotion back to the Premier League.
With departed striker Toney watching in the stands after his move to Al-Ahli in Saudi Arabia, the hosts proved too strong for Russell Martin’s men. They created the superior chances and capitalised on an error-strewn performance from Southampton’s backline.
Mbeumo opened the scoring on the stroke of half-time before doubling the lead halfway through the second period and Wissa then got on the scoresheet moments later to continue Brentford’s strong start to the campaign. Yukinari Sugawara bagged a consolation in injury time for the Saints.
Brentford sit in fifth place ahead of the first international break, while Southampton are second-bottom of the league table with zero points.
Data debrief: Wissa continues to prove effective at home
Wissa now has five goals and two assists in his last seven matches at the Gtech Community Stadium.
Brentford have recorded consecutive home league wins for the first time since last November, and the first time in their opening home games since August 2018.
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