Cristiano Ronaldo was back in the Manchester United team to face Tottenham on Saturday after missing the derby drubbing, but there was no Bruno Fernandes.
The absence of Ronaldo for last Sunday's 4-1 defeat to Manchester City sparked a fresh wave of speculation about the 37-year-old's United future.
It was put down to a hip problem by interim manager Ralf Rangnick, but former United captain Roy Keane was among those who questioned whether that told the full story.
Ronaldo's Manchester derby absence came after a run of one goal and zero assists in 10 games for United in all competitions this calendar year. That compares to 12 goals and three assists in his opening 19 games upon returning to United from Juventus at the end of August.
He was restored for the visit of Spurs, but Portuguese compatriot Fernandes was surprisingly not involved, three days before United tackle Atletico Madrid in the second leg of their last-16 Champions League tie.
Rangnick said: "Bruno is ill, unfortunately. He couldn't train yesterday and is therefore not available for the game. Hopefully, he will be back for Tuesday but, today, he is out."
NFL legend Tom Brady, a friend of Tottenham striker Harry Kane, was at Old Trafford for the game.
There was a United start for Marcus Rashford, whose own future has been cast into doubt by reports suggesting he could seek a move at the end of the season. He replaced Anthony Elanga, while Edinson Cavani was named on the bench after recent fitness worries.
Goalkeeper David De Gea featured for the home side after a COVID-19 false positive, while Raphael Varane was back from a coronavirus absence to start alongside Harry Maguire in central defence.
Rangnick told MUTV: "We had a false positive test on David De Gea last night. We then decided to have a second test that was negative and then a PCR test that was negative again, and that's why we can play him after all."
Eriksen recovery 'going well' with hope of Man Utd return before end of season
Christian Eriksen is set to step up his recovery from injury as he attempts to at least play some role in Manchester United sealing a potential treble.
The Manchester United midfielder suffered an ankle injury during the FA Cup victory over Reading in January, sparking fears that it would result in a premature end to his maiden campaign at Old Trafford.
However, the Denmark international is optimistic that he can return before United's season – which could result in further honours in the FA Cup and Europa League following their EFL Cup triumph – comes to a close
"Yeah, it is going well. I have just started being outside as you saw [on Instagram] with football boots on," he told the club website.
"And then we take it from there, that is the next step. I have been in the gym for some weeks now and now it is time to do the next rehab session outside."
"I think earlier in my career I would have taken it a lot harder than I do now.
"You learn later on that it's just part of your career. Sometimes you are lucky, sometimes you are not.
"With this one particularly, when I can't do anything myself, when somebody came on to me, the mindset is just getting back as soon as possible in a healthy, strong way and not to get any setbacks."
Zaniolo hits out at Roma for treating him as a 'capital gain'
Nicolo Zaniolo hit out at Roma for "unfulfilled promises" and treating him as a "capital gain" after he joined Galatasaray last month.
Zaniolo left the Eternal City giants to join the Turkish Super Lig leaders for a fee €16.5million early in February.
The Italy midfielder had been expected to move on during the January transfer window, but he turned down a move to Premier League strugglers Bournemouth.
Zaniolo signed a four-year deal with Galatasaray after being left out on in the cold at Roma and the 23-year-old has pointed the finger at his former club over the way he was treated.
He told the Gazzetta dello Sport: "I could talk for hours about unfulfilled promises. They [Roma] told me I was a spearhead, instead I've always been considered just a capital gain.
"For two years I was told that the new contract was ready. In January of last year I would have signed for slightly more than what I was earning, because I was fine in Rome and I knew there were problems with Financial Fair Play. After much talk I'm bored. If I have to reflect on my farewell, I think others must do it too."
Zaniolo was hurt by being called a traitor.
He added: "It's something I'm very sorry about. Roma gave me everything, thanks to Roma I won and I made my debut for the national team, my son was born there. Being labelled that way was a big blow."
Zaniolo continued: "The truth will come out. I'm just saying that I've always trained, even if not with the others."
Much was made of a supposed fall-out between Zaniolo and Jose Mourinho, but the playmaker has no problem with the Roma head coach.
"He's a great coach and a great person," Zaniolo said of his old boss. "He made me play almost always. Sure, he's used to managing star players and I wasn't [one]. I would have liked to have him in four or five years, but he gave me so much anyway."
Courtois to miss Germany friendly due to adductor injury
Thibaut Courtois will miss Belgium's friendly against Germany on Tuesday due to an adductor injury.
The Real Madrid goalkeeper withdrew from the Red Devils squad on Sunday after sustaining a minor strain.
Courtois played in the Red Devils' 3-0 victory over Sweden in their opening Euro 2024 Group F qualifying match at Friends Arena on Friday.
The former Chelsea keeper will not face Germany in Cologne, though, after returning to Madrid.
Carlo Ancelotti will be hoping Courtois is fit when Los Blancos return to action against Real Valladolid in LaLiga next Sunday.
Romelu Lukaku's hat-trick ensured Belgium started Domenico Tedesco's reign as head coach with a resounding victory over Sweden in Solna.
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