Milan moved within one point of the Serie A summit with a hard-fought 3-1 win over Jose Mourinho's lacklustre Roma side at San Siro, who were reduced to nine men in the second half.
First-half goals from Olivier Giroud and Junior Messias put the hosts in a commanding position before Tammy Abraham dragged Roma back into the contest.
After a string of Mike Maignan saves kept the hosts' lead intact, Rick Karsdorp's sending-off for two bookable offences put paid to any hope of Roma earning a point, and substitute Rafeal Leao added a third on the break late on before Zlatan Ibrahimovic missed a penalty following another red card, this time for Gianluca Mancini.
Milan were handed a brilliant start, with Giroud dispatching an eighth-minute penalty after Abraham was adjudged to have handled Theo Hernandez's fierce volley.
Things quickly went from bad to worse for Mourinho's men. Giroud intercepted a dreadful backpass from Roger Ibanez, and although his strike came back off the post, Messias buried the rebound to double the hosts' lead after just 15 minutes.
The 2-1 half-time scoreline arguably flattered Roma, who found themselves back in the contest when Abraham diverted Lorenzo Pellegrini's shot past Maignan, seconds after being denied by the France international's reflex save.
Milan almost made another fast start in the second period, with Brahim Diaz crashing a fabulous effort against the bar on 50 minutes, before Maignan was forced into two more good saves by Abraham and Henrikh Mkhitaryan.
With 20 minutes remaining, the already-booked Karsdrop received his marching orders for a desperate lunch on Hernandez on the edge of the penalty area, killing the visitors' hopes of leaving with a result.
Alessandro Florenzi rattled the bar from the resulting free-kick, before Leao, returning from injury as a substitute, finished the contest with a late breakaway goal, his sixth of the season.
That was not the end of the drama, with Roma's Mancini joining Karsdrop for an early bath by bringing down Leao. Ibrahimovic, however, saw his penalty saved by Rui Patricio, maintaining some respectability for Mourinho's side.
What does it mean? Milan apply early 2022 pressure to Inter
Thanks to a raft of COVID-19 cases and Africa Cup of Nations call-ups, Stefano Pioli was forced to select a makeshift side, but they produced a largely accomplished display to move within a single point of cross-city rivals Inter in the title race.
Milan have also now won three consecutive league games against Roma for the first time since 1996.
Mourinho's men stay seventh, six points outside the top four.
Home comforts for Giroud
Former Arsenal and Chelsea man Giroud opened the scoring with his fifth league goal of the campaign, and all of the World Cup winner's strikes for Milan have come at San Siro.
Among all the other players to have netted five or more goals in a top-five European League this season, only Bruno Fernandes and Mattia Aramu have also scored all of theirs at home.
Milan press home their superiority
Pioli has masterminded Milan's title charge by implementing an exhilarating, high-pressing game at San Siro, forcing opponents into errors in perilous positions.
Going into this game, no Serie A team had attempted more than the Rossoneri's tally of 37 shots from high turnovers this season. This quality was on display once again, with Messias' crucial second goal originating from Giroud intercepting Ibanez's slack pass.
What's next?
Notwithstanding a continuation of the coronavirus-caused chaos that has engulfed Serie A this week, Milan travel to Venezia for Sunday's early kick-off, while Roma face a huge clash with Juventus at the Stadio Olimpico later that day.
Conte: Napoli need to focus on improvement, not Serie A lead
Napoli should pay little attention to their place at the top of Serie A, so says Antonio Conte, who has demanded improvement from his team.
Romelu Lukaku's second-half goal handed Napoli a 1-0 win over Roma on Sunday.
That victory sent Napoli back to the summit of Serie A, with Conte's side one point ahead of Atalanta, Inter, Fiorentina and Lazio, while Juventus are only four points back in a six-team title race.
Napoli needed to get back to winning ways after a draw against Inter and a 3-0 loss to Atalanta before the international break, and Conte insists his team must sharpen up.
"Before the match, I told the lads not to look at the table, but to focus on ourselves and improving what we are working on," Conte told Sky Sport Italia.
"I maintain that now too because we need to take a series of steps to raise the level.
"I was satisfied with the performance for a good 65 minutes today, we could’ve taken more of our chances and were up against a strong Roma who have great players.
"Roma were also making their debut under a new coach and therefore were very eager to prove themselves, but we still should've dealt with the final 15-20 minutes better, as we sat too deep and made it complicated for ourselves."
Roma, playing under new boss Claudio Ranieri, came close to equalising when Artem Dovbyk hit the woodwork with a header.
Ranieri came out of retirement to take charge of Roma following Ivan Juric's dismissal earlier in November, though the visitors had just six shots and accumulated only 0.6 expected goals (xG) at Stadio Diego Armando Maradona.
"If we look back, we have some problems and that is why I was called. We were up against a team that is fighting to win the Scudetto," Ranieri told Sky Sport Italia.
"Having said all of that, I am happy with the performance from my players. We made some mistakes that we will talk about during the week, but the hunger, the determination to get back on track was there.
"We have a lot of work to do, but I feel positive.
"We know there is work to be done, we have to focus on reacting rather than sitting there feeling sorry for ourselves.
"The [players] need the right character to help themselves and then others. Naturally, when I arrived, the team was a little closed up, but I think we started to open up a bit by the second half."
Keane doubts Man Utd will crack top four under Amorim this season
Roy Keane does not believe Manchester United will get back into the Premier League's top four under Ruben Amorim this season due to a "real lack of quality".
The Red Devils legend was speaking after United started life under the Portuguese with a 1-1 draw at Ipswich Town, as Omari Hutchinson cancelled out Marcus Rashford's second-minute opener.
Keane acknowledged Amorim has to be given time to turn things around at Old Trafford, but does not see United cracking the top four this season.
"You have to give the man a chance," Keane told Sky Sports. "But the threat going forward, it's a huge problem for Man Utd. It's not good enough.
"Do I believe they have the quality to get them back to top four? Absolutely not. The evidence is not there. It's the same old stuff. Predictable and a real lack of quality."
United created 0.9 xG compared to Ipswich's 1.75 and had fewer shots on target (four) compared to Ipswich (six) at Portman Road.
They did have more touches in the opposition box (16 to 11) but had fewer final-third entries (48 to 61) and big chances created (two to three).
Ipswich were extremely resilient opponents after their early setback, and Tractor Boys boss Kieran McKenna praised his side, particularly Hutchinson after he grabbed his first Premier League goal.
"I thought he (Hutchinson) was a big threat first half, naturally more a winger, but most teams are going to press us high and in the spaces in the middle of the pitch having a dribbler in the middle of the pitch who's elusive and hard to pick up can be a big threat," he told Sky Sports.
"I think it's his first goal in the Premier League he'll be happy to have that of his back and he's improving."
"The first half, it's a blow to concede the early goal but I thought as the half went on we grew in the ascendancy, and the intensity of pressing and work on the ball.
"I thought we were the dominant team in the first half and deserved to be going in at least level. Second half in fairness, Man Utd had more control. It was difficult, we had to defend with real discipline on shape."
Leganes 0-3 Real Madrid: Mbappe and Bellingham score as Blancos close on Barcelona
Kylian Mbappe and Jude Bellingham were both on target as Real Madrid moved to within four points of LaLiga leaders Barcelona with a 3-0 win at Leganes.
Federico Valverde also scored for Carlo Ancelotti's side, who still have a game in hand on leaders Barca, who were pegged back in a 2-2 draw with Celta Vigo on Saturday.
Mbappe ended a goal drought of over 400 minutes after being teed up by Vinicius Junior shortly before half-time, moments after Leganes had surrendered possession near the edge of their own area.
Madrid dominated possession throughout the second half and doubled their advantage in the 66th minute, Valverde drilling a low effort home from a free-kick won by Bellingham.
Bellingham later got in on the act with a header on the rebound after substitute Brahim Diaz rattled the crossbar, as Madrid cruised to back-to-back league wins.
Data Debrief: Dirty work pays off for Madrid
Mbappe's opener, scored at a vital time shortly before the interval, set Madrid on their way to victory on Sunday.
Eduardo Camavinga and Bellingham both pressed high to help the visitors recover possession in the build-up, and Madrid have now scored five goals resulting from high turnovers in LaLiga this season – the most of any team across Europe's top five leagues.
This was the first time Ancelotti had faced Leganes in LaLiga, and he has now beaten all 28 different opponents he has come up against in the competition.
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