Zinedine Zidane is frustrated by Real Madrid's injury problems and admitted it is not easy rotating his side between matches.
Defender Dani Carvajal suffered another injury setback this week, just three games into his comeback, and is now expected to miss the rest of the season.
Carvajal joins Lucas Vazquez, Ferland Mendy and Federico Valverde on the sidelines, but skipper Sergio Ramos is back in training and could feature against Osasuna on Saturday.
Madrid face another tight turnaround in fixtures, with the LaLiga clash against Osasuna followed four days later by a Champions League semi-final second leg with Chelsea.
Zidane has suggested he will not rest any key players this weekend, though, as draw specialists Madrid seek just a second win in six matches in all competitions.
"As a coach, of course I am very frustrated with the relapses," Zidane said at a pre-match news conference on Friday.
"I want my players healthy. I never want them injured, not even the smallest issue. When one relapses two or three times, I am not happy. But we have to always look forward.
"I can't explain the number of setbacks. All teams have had problems. With the issues we've had, getting to this point and still being in contention means a lot.
"I'm very happy with the players' character and what we have got out of them. We all believe in what we do, each one of us, and that is fundamental.
"It's not easy to manage a squad like Madrid's. Everyone has an opinion but inside it's not easy. It's my job and I do my best. It's a rare year and we will continue to fight.
"Not everyone will be able to play tomorrow, but we cannot think about Wednesday before tomorrow. Whatever happens, in life, you have to think about doing it well tomorrow.
"This is what we are going to do - go out with the best possible team to win the three points. If you think differently, you don't reach all of your targets."
Madrid's issues could be compounded for their trip to Chelsea next week as Marcelo has been called up to monitor a polling station during local elections a day before the match, which is poised at 1-1.
However, Zidane has indicated that the experienced defender will still be part of Los Blancos' travelling party next week.
"It is what it is," Zidane said. "He is going to fulfil his obligations, but nothing changes. He will still be with us on Wednesday."
Madrid have drawn two of their last three league games, but their hopes of retaining the LaLiga title were boosted on Thursday with Barcelona's shock home loss to Granada.
Zidane's side are level on points with Barca and are only two behind leaders Atletico Madrid, with fourth-placed Sevilla just a point further back.
Los Blancos have won their last 10 games against Osasuna in LaLiga, scoring an average of 3.3 goals per game, but Zidane is taking nothing for granted this weekend.
"The league is always complicated," he said. "That will be the case right until the end. We cannot focus only on the defeats of our rivals - we have to look at ourselves.
"We want to win the league and will try until the end, but we can only think about tomorrow.
"We are in the mix, fighting. We are focused on the day-to-day and are preparing for the match. We are near the end of the season and we are concentrating on this.
"There are three points to play for and we are going to do everything to win them."
Hurtig the hero after late goal sends Arsenal into Champions League quarters
Lina Hurtig's 89th minute winner ensured Arsenal progressed to the quarter-finals of the Women's Champions League after edging Juventus 1-0 on Thursday.
After being frustrated for large parts of the encounter, Hurtig bundled home from close range after Martina Lenzini's poor clearance to book the Gunners' place in the last eight.
Despite Arsenal dominating the early exchanges, it was Juventus who had the first sight of goal, though Eva Schatzer's effort was easy for Daphne van Domselaar to gather.
In a first half that saw just two shots on target, both coming from the visitors, Renee Slegers' substitutes proved to be the difference for Arsenal.
Slegers introduced Beth Mead, Stina Blackstenius and Hurtig late on, with the latter somehow putting Kim Little's cross over the bar from five yards out.
However, the Swede would atone for her earlier error, combining with fellow substitute Blackstenius to net against her former club and send them out of the competition with two group games remaining.
Meanwhile, in Group D, Barcelona edged closer to the quarter-finals of the competition with a convincing 4-1 victory over St. Polten at the Generali Arena.
The reigning champions are still three points behind Manchester City following their 2-1 win over Hammarby, and know a win against the Swedes next month will see them progress.
Kika Nazareth opened the scoring in the 20th minute after capitalising on a mistake by Kamila Dubcova, notching her second nine minutes later from close range.
Barca found themselves three goals up at the break when Vicky Lopez netted her first goal in the competition to put the result beyond doubt.
There was also a landmark moment for Alexia Putellas, who netted her 200th goal for the club with a well-taken effort into the far corner.
Valentina Madl took some of the shine off an otherwise impressive display from the visitors, who have now taken their tally to 20 goals from their four matches in the competition.
Guardiola agrees two-year contract extension with Man City
Pep Guardiola will be Manchester City manager for at least two more seasons after 2024-25, after he signed a two-year contract extension on Thursday.
The 53-year-old was coming to the end of his City deal, which was due to expire at the end of the current campaign, but he has opted to remain at the Etihad Stadium.
The deal itself will take Guardiola's tenure at the club to over a decade, making him City's longest-serving manager since Les McDowall in 1963.
There had been suggestions that he may leave at the end of the season following the announcement that director of football Txiki Begiristain was on his way out.
Guardiola was strongly linked with the England job after Gareth Southgate resigned in the wake of their Euro 2024 final defeat, but the Football Association appointed Thomas Tuchel last month.
“Manchester City means so much to me," Guardiola said. “This is my ninth season here; we have experienced so many amazing times together. I have a really special feeling for this football club.
“That is why I am so happy to be staying for another two more seasons.
“Thank you to everyone for continuing to trust and support me – The Owner, The Chairman Khaldoon, Ferran, Txiki, the players and, of course, the fans… everyone connected to Manchester City. It has always been an honour, a pleasure and a privilege to be here.
“I have said this many times before, but I have everything a manager could ever wish for, and I appreciate that so much.
“Hopefully, now we can add more trophies to the ones we have already won. That will be my focus.”
Having been appointed in 2016, Guardiola is by some distance Manchester City's most successful manager of all time, having won 18 major trophies during his time at the club.
That list includes their first-ever Champions League triumph in 2023 and six Premier League titles, including an unprecedented four on the spin.
He also boasts a 72.04% win percentage across all competitions, which is unsurprisingly the highest of any full-time City manager in history.
Shaw at the double as Man City progress in Champions League
Khadija Shaw scored twice as Manchester City beat Hammarby 2-1 to seal their place in the Women's Champions League quarter-finals.
Gareth Taylor's team entered Thursday's game with a perfect record in Group D, and their fourth win in as many European matches ensured they finished in the top two.
Shaw—the leading scorer in the Women's Super League this season with eight goals—put them ahead in the 31st minute, driving into the area after taking in Yui Hasegawa's pass before seeing her shot deflect into the top corner.
Shaw was booked for celebrating in front of the home fans despite appearing to have objects thrown at her from the stands, and Hammarby should have levelled when Julia Blakstad fired wide 10 minutes later.
The hosts did draw level three minutes into the second half as Ellen Wangerheim tapped home while City's Laura Blindkilde Brown was down appealing for a free-kick.
That parity was short-lived, though, as Shaw blasted into the top corner from 25 yards out, taking her overall tally for this season to 12 goals in all competitions.
In Group C, meanwhile, Bayern Munich lost their perfect record as they played out a 1-1 draw with Valerenga, boosting Arsenal's hopes of topping the pile.
Jovana Damnjanovic came off the bench to put Bayern ahead 15 minutes from time in Norway, but Elise Thorsnes headed home following an 88th-minute corner to snatch a point for the hosts.
Arsenal could now move within a point of Bayern when they face Juventus in Group C's other match later on Thursday.
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