Ronald Koeman described Barcelona's failure to beat Cadiz as more disappointing than their Champions League humiliation at the hands of Paris Saint-Germain.
Barca followed up their 4-1 home defeat to PSG in the last 16 first-leg clash on Tuesday with a 1-1 draw in LaLiga against relegation-threatened Cadiz.
Lionel Messi marked his record 506th LaLiga game for the club with a 32nd-minute penalty, but Alex Fernandez levelled from the spot late on after Clement Lenglet was adjudged to have fouled Ruben Sobrino.
The draw meant Barca missed the chance to pull within six points of league leaders Atletico Madrid, who were beaten at home by Levante on Saturday.
"It is disappointing," Koeman said. "These types of games have to be won and we did not.
"It was a great opportunity lost after the loss of Atletico. I am very disappointed, more so than on Tuesday.
"We could not afford to let two points get away. I don't like to blame individual players but we were not up to the task offensively and we have to defend differently. For our quality, we had to win.
"The lead was very narrow and they could equalise at any time, which is what happened. You leave the door open for them to draw at the end if you don't kill the game and score the second.
"It was difficult for us to create opportunities because they were behind the ball and there was no space. We lacked freshness in attack."
Barcelona have failed to keep a clean sheet in eight successive games across all competitions for the first time since 2015.
Despite their issues at the back and the eight-point gap to the summit, Koeman is not giving up hope of Barca posing a serious challenge to Atletico.
"We can still do something," he added. "There is no team that wins games easily.
"But we must recognise that opportunities like this cannot be missed anymore. I don't think it is unforgivable, but it was an opportunity to close the gap.
"[The league] is not more complicated than before. No team is unbeatable, nor are they going to win every game. There are still options. But we have dropped two important points."
Man City title hopes rocked by Shaw injury
Manchester City's title hopes took a blow with the announcement that Khadija Shaw has been ruled out for the remainder of the season with a foot injury.
Shaw currently sits top of the Women’s Super League golden boot race with 21 goals in 18 games this season, a total which puts her well ahead of closest rival Lauren James, who is eight behind.
But she picked up her injury during Man City's 5-0 WSL victory over West Ham last weekend, a match in which she had scored twice in the first half, and will now miss the crucial final weeks of the top-flight campaign.
City have been reliant on the Jamaican's goals this season and will miss her in what is likely to be one of the most exciting run-ins in WSL history.
Chelsea sit three points behind City, however they have a game in hand and goal difference could end up being the determining factor if both teams are able to win all their remaining games.
The Citizens’ manager Gareth Taylor confirmed the Shaw blow in his pre match press conference ahead of Sunday’s clash with Bristol City, saying: “We have an issue with Bunny, she’s sustained a foot injury which will keep her out of the game for certain and potentially longer.
“It’s such a difficult one for Bunny because she’s had an incredible season.
“We had a feeling it might be an issue when she came off the pitch [against West Ham] even though it was non-contact.
“She’ll be well looked after by the medical team.”
City will have to think about who can fill the shoes of their star striker, but Taylor was confident about his team’s options despite the injury to Shaw.
"Bunny is our main number nine, but Mary [Fowler] has played there, Lauren [Hemp] has played there. Chloe [Kelly] is capable of playing there, Jess [Park] can do a really good job there," he said.
"Of course, we all understand what Bunny brings, she is such a box player, she gives us a different way of playing. Now, we will have a different kind of number nine."
City did, however, have some good news to share as they have tied down Lioness Lauren Hemp on new three-year contract extension keeping her at the Joie Stadium until 2027.
Hemp has won four trophies, while scoring 65 goals in 157 appearances, and has been a key player in the evolution of Taylor’s side.
Man City have secured the winger, who was out of contract at the end of the season and has attracted the attention of some of Europe's elite clubs such as Barcelona.
This term she has proved as productive as ever for City, scoring nine goals and adding six assists. She will also be key in the coming matches after the news of Shaw's injury misery.
"I feel at home here in Manchester," Hemp said after signing the deal.
"With the squad we have here, we are always learning and it’s so special to be involved at a club where we’re capable of achieving anything.
"I’m so passionate about this club and there’s no place I’d rather be. I’m very excited to keep this journey going for the next few years."
Edwards urges Luton Town to ignore scrutiny on relegation battle
Rob Edwards is keen for Luton Town to ignore the scrutiny surrounding them in the relegation battle as they prepare for another big game against Wolves.
The Hatters sit one point from safety in the relegation zone after back-to-back 5-1 defeats against Manchester City and Brentford.
While Nottingham Forest also lost last weekend, being beaten 2-0 by Everton, Burnley beat Sheffield United to move them two points behind Luton.
Asked how he is handling the pressure of the relegation battle with only four games left, Edwards said: “The stakes are high already, we all know what it means and it's really important to everyone that's in this at the moment, a number of clubs that are still fighting to try and avoid it and be in the league next season, it's so important.
“Everyone wants to try and stoke the fire I think. We've got a title race on at one end and obviously, there's a relegation battle we're involved in. It's exciting, it's good that we're in the fight, and we've got a chance to get out of it, but really, all I am concerned about right now is our performance tomorrow.”
Glasner challenges Crystal Palace to extend winning run
Oliver Glasner is hopeful that Crystal Palace can maintain their recent winning run when they travel to Fulham on Saturday.
After a run of five games without a victory, the Eagles have won each of their last three games, beating Liverpool, West Ham and Newcastle United.
Their 2-0 win over the Magpies on Wednesday also secured their Premier League safety for another season.
Glasner has given credit to his team’s attitude in turning around their recent run of form but does not want them to slow down despite reaching their goal.
He said: “The players give us confidence because they are listening. Every day we were sitting here and having a meeting and showing them videos and nobody was sleeping, so that gives us good feedback!
"Now we have 39 points and I think it shouldn't be our target to say ‘39 points, oh well done, staying in the Premier League’ because then I would say 'come on guys, go wherever you want and take vacations' – but no.
"We want to improve, we want to win games, and we have the next chance tomorrow at Fulham."
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