Atalanta claimed their first victory of this season's Champions League following a commanding 3-0 victory over Shakhtar Donetsk.
Ademola Lookman scored, while Berat Djimsiti and Raoul Bellanova were also on target for Gian Piero Gasperini's side, as they eased to three points at VELTINS-Arena.
La Dea broke through in the 21st minute following a short corner, from which Lookman's cross was neatly controlled and converted by Djimsiti.
Lookman, the hat-trick hero in last season's Europa League final, doubled the visitors' lead when he slotted home from Sead Kolasinac's square ball just before half-time.
The Nigeria international, who also hit the crossbar during the first period, was involved again as Atalanta put the contest beyond doubt within three minutes of the restart.
Indeed, Lookman played the ball out wide to Davide Zappacosta, whose cross was nodded in from close range by Bellanova.
Data Debrief: Lookman shines as Atalanta soar
Once again, Lookman produced the goods on a big European night for Atalanta.
The forward became only the second Atalanta player after Duvan Zapata to both score and assist in a single Champions League game.
He has now been directly involved in eight goals in his last seven games in major European competition (six goals, two assists), which is two more than he registered in his first 22 such matches.
By contrast, Shakhtar failed to register a single shot on target in a Champions League game for the first time since facing Roma in March 2018, and first time overall on home soil.
'It's a great night for everyone' - Genesio revels as Lille shock Madrid
Bruno Genesio revelled in "a great night for everyone", as "incredible" Lille stunned Champions League holders Real Madrid 1-0 at Stade Pierre-Mauroy.
Jonathan David's first-half penalty - after Eduardo Camavinga handled from Edon Zhegrova's free-kick - ended Madrid's 14-match unbeaten streak in this competition, while condemning them to a first reverse overall in 36 games.
Genesio also had Lucas Chevalier to thank after the Lille goalkeeper made a string of superb saves to keep Carlo Ancelotti's side at bay, including a wonderful instinctive stop to thwart Antonio Rudiger right at the death.
Indeed, Madrid simply had no answer to their stubborn hosts, despite the introduction of a fit-again Kylian Mbappe during the second half.
And Genesio saluted his players for their efforts in delivering a memorable result.
"What this team did is incredible," he said. "We try to put things in place, but you need the players to believe in the plan for this kind of upset to happen.
"You have to do everything perfectly, you need a keeper who makes the decisive saves, a striker who scores, and a bit of luck.
"We played a very good first half, we played together. It's a great night for everyone.
"We saw that Real like to cut inside, so we put intensity in that sector - even if we had to abandon possession sometimes.
"Then, it was all about pressing when it mattered. Everything worked perfectly, it was an ideal scenario - even if we suffered a lot in the last 25 to 30 minutes, but Lucas made the saves we needed."
Motta praises Juve spirit after thrilling fightback at Leipzig
Thiago Motta hailed Juventus' team spirit after they shrugged off two injuries and Michele Di Gregorio's red card to secure a thrilling 3-2 Champions League win over RB Leipzig.
Juventus, who are yet to concede a goal in Serie A this season, twice had to fight back from a goal down before securing the win with a late goal from Francisco Conceicao.
They endured a nightmare start as captain Bremer and winger Nicolas Gonzalez were both withdrawn after suffering injuries.
They then went down to 10 men when Di Gregorio was dismissed for handling outside his area, but Dusan Vlahovic's brace had them level before Conceicao showed great feet to tuck home an 82nd-minute winner.
"It was a good match, even in the first half where we made some mistakes in the details," said Motta.
"In the second half, we did better, even playing with 10 men. It was a great performance and a great win.
"Courage from the boys, they were determined to push forward and hurt the opponents.
"Even with a man down, we had that feeling, so why step back? We kept pushing, and we did it well right until the last minute."
Two-goal hero Vlahovic echoed those sentiments, saying: "I'm really happy, especially for the team. We are becoming a real unit.
"We fought together, kept pressing even when we were down to 10 men, and in the end, we deserved to win. It was a great match, and fortunately, we came out on top."
Dinamo Zagreb 2-2 Monaco: Zakaria snatches point at drenched Stadion Maksimir
Monaco came from two goals down to snatch a 2-2 draw at Dinamo Zagreb in the Champions League at a rain-sodden Stadion Maksimir, with Denis Zakaria equalising with an 89th-minute penalty.
Petar Sucic put Dinamo ahead in first-half stoppage time with a delightful chipped finish, later doubling their lead in 66th minute when Martin Baturina rifled home from outside the area.
Having been crushed 9-2 at Bayern Munich in their opening game, it looked like the Croatian side would bounce back in style, with Monaco struggling to get going on a sodden pitch.
However, Mohammed Salisu headed in from a corner with 16 minutes left to provoke a Monaco onslaught, and Maxime Bernauer fouled Folarin Balogun to concede an 89th-minute spot-kick.
Zakaria converted to put Monaco on four points after they beat Barcelona in their first match, with Dinamo defender Nenad Bjelica subsequently sent off when he picked up a second booking for dissent.
Data Debrief: Monaco show fighting spirit
Monaco looked set for a demoralising defeat in Croatia when they went 2-0 down, struggling to get their slick passing style to work on a pitch that was close to waterlogged.
However, they showed great resilience to fight back in the latter stages, avoiding defeat from two or more goals down in a Champions League match for the first time since May 2004, when they earned a 2-2 draw versus Chelsea en route to making the final.
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