Napoli emphatically ended Lecce’s 100 per cent home record in Serie A with a 4-0 victory at the Stadio Via del Mare.
Goals from Leo Ostigard and substitutes Victor Osimhen and Gianluca Gaetano had the visitors in control before Matteo Politano converted a penalty in added time.
Both teams started the day in the top six with 11 points from six games but Rudi Garcia’s men were good value for their fourth win of the campaign to maintain the pressure on the Milan clubs.
Garcia made three changes following the convincing 4-1 defeat of Udinese in midweek, with Mathias Olivera, Giovanni Simeone and Jesper Lindstrom coming in for Mario Rui, Osimhen and Politano.
Napoli had early control in sunny Puglia with Lecce, the season’s surprise package, struggling to make an impression.
The visitors’ early enterprise was rewarded in the 16th minute when they took the lead, central defender Ostigard heading in Piotr Zielinski’s free-kick from the left unchallenged at the far post.
Lecce won only three home games last season but had already beaten Lazio, Salernitana and Genoa this time around and falling behind sparked them into life.
Roberto D’Aversa’s men, who saw their best start to a Serie A season end on Tuesday with a 1-0 loss at Juventus, threatened in the 25th minute when Nikola Krstovic brought a low, diving save out of goalkeeper Alex Meret.
Central defender Marin Pongracic then wasted the Salentini’s best first-half chance on the half hour, firing over from seven yards after a corner on the right.
However, Napoli finished the half strongly and could have led by more than one goal at the interval.
In the final five minutes of the first half, Simeone saw a powerful right-foot shot go just wide, Wladimiro Falcone saved from Zielinski, then Khvicha Kvaratskhelia was narrowly off-target with a free-kick.
Osimhen replaced Simeone for the second half, and within six minutes of his introduction he had doubled Napoli’s lead with his fifth goal of the season, a header off the post from close range following Kvaratskhelia’s cross.
Gabriel Strefezza had the ball in the visitors’ net in the 57th minute with a close-range header but it was ruled out for handball in the build-up by Krstovic.
With a Champions League match against Real Madrid coming up on Tuesday, Garcia rotated his players, first replacing Lindstrom and Kvaratskhelia with Giacomo Raspadori and Politano.
Raspadori’s low left-foot shot was saved by Falcone in the 67th minute, before Jens-Lys Cajuste came on for Stanislav Lobotka with 14 minutes remaining.
Lecce could not find the breakthrough they needed to set up a tense finish and Napoli made it 3-0 when Gaetano, the last of their five substitutes to be introduced, increased the lead with two minutes remaining.
Less than five minutes after his introduction, the attacking midfielder fired home powerfully from the edge of the penalty box.
There was still time for a fourth goal, Politano sending Falcone the wrong way from the penalty spot after Ylber Ramadani had been penalised for fouling Gaetano.