Manchester United will not appeal against a four-game domestic ban given to Casemiro after his red card against Southampton, with Raphael Varane backing them to cope in his absence.
A VAR review saw Casemiro shown a straight red card for a forceful challenge on Carlos Alcaraz during the first half of Sunday's goalless draw at Old Trafford.
The midfielder was also sent off in a 2-1 victory over Crystal Palace last month, making him the first United player to receive two red cards in a single Premier League season since Nemanja Vidic in 2013-14.
His second dismissal of the campaign means he must serve a four-match domestic suspension, missing Sunday's FA Cup quarter-final against Fulham as well as league meetings with Newcastle United, Brentford and Everton.
Erik ten Hag questioned Casemiro's dismissal after Sunday's game, claiming the 31-year-old is "tough but fair" and labelling the decision "debatable".
On Monday, however, United confirmed they would not launch an appeal against the Brazilian's suspension, having determined "there was not a high chance of being able to overturn the ban".
United have suffered as many defeats in seven Premier League games without Casemiro (W3 D1) as in 19 (W12 D4) with the former Real Madrid man this term, while their win rate drops from 63.2 per cent to 42.9 per cent in his absence.
Varane, however, believes the depth of their squad will now come to the fore, saying: "He's a player who is very important for us. He brings balance to the team and to the squad.
"But we have a great squad and we have to find another balance without him. We have good players in every position on the pitch and we are ready for the next games.
"I think he was very disappointed because nobody wants to be off the pitch before the end. We can't be happy with the decision he [the referee] takes but that's part of football."
Casemiro will be available when United travel to Real Betis for the second leg of their Europa League last-16 tie on Thursday, after the Red Devils posted a 4-1 win in the first fixture at Old Trafford last week.
Frank praises Brentford's pressing, sees no tactical revamp with Toney departure
Thomas Frank heaped praise on Brentford's pressing following their 3-1 victory over Southampton on Saturday.
Bryan Mbeumo scored twice from Brentford's forwards forcing the Southampton backline into errors as the Bees earned their second Premier League win of the season.
This did not go unnoticed by Frank, who believes his side rank as one of the best in the league when it comes to that specific aspect.
He told BBC Sport: "They made errors because we pressed them unbelievably well. I think we are one of the best teams to do the high pressure in the Premier League.
"The players are so committed and that is the reason why we capitalised on errors from Southampton.”
Despite the departure of Ivan Toney to Al-Ahli, Frank does not think their style of play will have to be restructured too much, with both Mbuemo and Yoane Wissa enjoying productive starts to the season in his absence.
Frank said: “Ivan is a fantastic player, I'd love to have him in the team but he has his own journey and is going elsewhere.
"Our style of play hasn't changed. Wissa and Ivan are different players but the style doesn't change.”
Southampton boss Russell Martin was frustrated with his side’s mistakes at crucial moments, believing their performance was far better than the scoreline suggested.
He said to the BBC: “We made two mistakes that we were punished for, which is frustrating and disappointing.
"I saw lots of good things to feel positive about. I feel a lot better this week than I did after the Nottingham Forest game.”
Guardiola has 'no words' for hat-trick hero Haaland
Pep Guardiola was lost for words to describe Erling Haaland after his eighth Premier League hat-trick fired Manchester City to a 3-1 victory over West Ham.
Having scored a treble to help City claim a 4-1 win over Ipswich Town on matchday two, Haaland did likewise on Saturday to keep them perfect as they edged out the Hammers at the London Stadium.
Haaland's seven goals this season are the most any player has ever netted in the first three matches of a Premier League campaign, while only Sergio Aguero (12), Alan Shearer (11) and Robbie Fowler (nine) have ever helped themselves to more match balls in the competition.
Across English football's top four tiers, he is also the first player to score two hat-tricks in a team's first three games of a league season since Bradford City's Paul Jewell in 1994-95.
The Norwegian has now scored more than once in 26% of his Premier League matches (18/69, eight hat-tricks, 10 braces), leaving Guardiola in disbelief.
"There are no words for him," Guardiola told BBC Sport.
"All we can do is make him play better and better and give him as many balls as possible into the box. It's what we have to do. We are there and we added quality.
"This is a team. When you have to run backward, no one asks who has to do it. Everyone has to. When we see Erling doing that, it is fantastic."
Haaland himself, meanwhile, believes having an extended pre-season due to Norway missing out on Euro 2024 has helped him start the season in peak condition.
"I feel good. I feel energised. I had a long vacation and a long pre-season. I'm feeling good," Haaland told City's website.
"The years here have gone quick and it's been going like, 'bam bam bam', now I have a little bit of rest in my body and my feet. I feel really good now and I'm ready for more.
"I feel more refreshed and more energised. So when you do that you can practice on things you want to become better at in training. I feel good. I want to become better. I'm happy."
City sit top of the early-season table with nine points from nine available and saw last season's runners-up Arsenal slip up on Saturday, drawing 1-1 with Brighton and Hove Albion.
Haaland, though, feels it is too early to think about the title race, adding: "They [City's rivals] haven't slipped up yet. Three games, nine points. This is a great start.
"But let's not think too far ahead, because there’s potentially 70 games left this season. Let's breathe a bit and take it game by game."
Lopetegui rues missed opportunity as West Ham lose to Man City
West Ham manager Julen Lopetegui was not encouraged by the performance of his team despite losing 3-1 at home to Manchester City in their third league game.
“It is true that City is one of the best teams around the world for sure… but it is also true too that in the second half we have been very close to a draw,” he said speaking to BBC Match of the Day.
“I think we have played one very good second half. The start has been very good for us too.”
West Ham threatened for extended periods of the match and had chances to level the match at 2-1 down, with the best coming from Mohammed Kudus as he smashed a shot against the bar in the second half.
They also started the game brightly before going a goal down inside 10 minutes.
“In my mind we started very well, being aggressive,” said Lopetegui.
“We know in this plan normally they have initiative, it’s very difficult to not concede initiative then. That’s why you have to do a lot of very good things to overcome them.
“In the second half we had chances, I think we kept the ball much more, much more, and didn't concede a lot of chances."
But the hosts were ultimately undone by the brilliant finishing of Erling Haaland, who scored his second hat-trick in as many matches.
“He is one of the best players in the world, that's why he plays for Manchester City,” he said.
“You have to compete with these kind of players. City has the power and the quality to create chances.”
But ultimately, he was left frustrated at the sense of a missed opportunity and that his team were unable to earn themselves a draw that hadn’t seemed implausible during the match.
“Today I think the first goal was a pity for us but I’ve said it. I was happy with the performance think we were able to draw but again they damage us,” he said.
“Against this kind of team, if you make a mistake they don’t forgive. This is the difference they have… A little mistake they punish you, they punish us.
“We have to improve, to know to compete against this kind of team to be close to perfection.
“Don't make mistakes, be calm, defend well… we have quality players too.”
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