Simone Inzaghi could not assure Romelu Lukaku he would start again against Porto despite ending his goal drought on Saturday.
Lukaku has scored only three times since returning to Inter at the start of this season.
It has been a difficult campaign for the Belgium forward, who also failed to net at the World Cup in Qatar.
But a penalty against Udinese on Saturday gave Lukaku his first Serie A goal since August ahead of Wednesday's Champions League last-16 first leg against Porto.
That does not mean Lukaku is certain to start, however, as coach Inzaghi said in his news conference there were "doubts" about his line-up.
Edin Dzeko would be the obvious alternative to Lukaku, having netted 11 in all competitions this season, although the pair started together against Udinese.
Asked specifically about Lukaku and midfielder Marcelo Brozovic, Inzaghi said: "Lukaku has been working for longer and is improving. He is putting a great deal of effort into it.
"As for both, tomorrow we will try to make the best choices for Inter.
"Those who do not start will still be useful in the game. In games like these, the final minutes are those in which decisive actions can occur and spaces are freed up to exploit."
Inter have not been past the last 16 of the Champions League since the 2010-11 season, when they were playing as defending champions.
But having emerged from a difficult group that also included Barcelona and Bayern Munich, confidence is high.
"We face this tie with great confidence," Inzaghi said. "We reached it with an incredible path – on paper, Barcelona and Bayern Munich were teams that everyone wanted to avoid.
"You can see what Barca are doing in La Liga, and we know what Bayern are."
Maresca confirms James will miss Leicester clash with hamstring injury
Enzo Maresca confirmed that Reece James has suffered another hamstring injury and will miss Chelsea's Premier League fixture against Leicester City on Saturday.
James made 11 appearances in all competitions last season before undergoing hamstring surgery, which was designed to help him overcome his series of injuries.
He returned to action in Chelsea's 2-1 defeat to Liverpool last month, completing his first 90 minutes in 569 days a week later against Newcastle United.
Though his latest injury setback is his eighth hamstring problem in four years, while also picking up thigh, ankle and muscle issues along the way.
Maresca played down concerns about a long-term lay-off but confirmed James will miss Saturday's match at the King Power Stadium.
"We have just one injured player and that's Reece, who unfortunately felt something small in training two days ago, and we don't want to take a risk for the weekend," he said.
"It's a hamstring, muscular problem. We will see, we don't know for how long, for sure [we want him fit for longer]. At the moment it is not happening, but we hope it will happen soon.
"He is out this weekend, but hopefully he can be back soon. It's probably difficult that he can be available for the Conference League [next Thursday], but hopefully soon."
Since his debut season in 2019-20, James' most appearances came in the 2020-21 campaign, featuring 47 times in Chelsea's Champions League winning season.
His best run of matches during that time is six in May 2021, but he managed just 482 minutes under Mauricio Pochettino in all competitions last season.
James has, however, managed more minutes (6138) in the Premier League since the 2020-21 season than any other player in the current Chelsea squad, though Enzo Fernandez (4375) is second, despite only joining the club in January 2023.
Serie A side Genoa confirm sacking of head coach Gilardino
Serie A side Genoa have confirmed the departure of their head coach Alberto Gilardino, with Patrick Vieira reportedly on his way in.
Gilardino, a World Cup winner with Italy in 2006, leaves the club with them sitting just one point above the relegation size with 10 points from 12 matches this season.
A former striker who played for clubs including Genoa, Parma, AC Milan and Fiorentina, Gilardino took charge of Genoa in 2022 and helped them earn promotion to the top division before a 11th-place finish during the 2023-24 season.
"The club thanks Gilardino for the goals achieved together over the years and wishes him the best for his career," Genoa said in a statement.
The 42-year-old saw his side salvage a late 1-1 draw against Cesc Fabregas' Como in their last match before the international break.
Genoa were also knocked out of the Coppa Italia in the second round following a defeat to Sampdoria on penalties in September.
Arsenal legend Vieira is set to replace him, according to multiple reports.
The former France midfielder has been out of work since leaving Strasbourg by mutual consent in July.
Doncic backs Mbappe to turn fortunes around at Real Madrid
NBA superstar Luka Doncic has backed Kylian Mbappe to "figure it out" after his underwhelming start to life at Real Madrid.
Mbappe has scored eight goals in 16 games for Madrid in all competitions since joining as a free agent following the expiration of his Paris Saint-Germain contract.
He has gone four matches without a goal – a run that includes losses to Barcelona and Milan – and has been left out of France's latest squad.
However, Dallas Mavericks guard Doncic – a Real Madrid supporter due to his previous ties with the sports club – can see Mbappe turning things around.
"Obviously [their season] could be better," Doncic told Managing Madrid after the Mavericks' win over the San Antonio Spurs on Saturday.
"But when you get a guy like Mbappe, it takes some time to get used to it. We'll figure it out."
Mbappe has scored six goals in 11 LaLiga appearances for Madrid but has underperformed his season's expected goals (xG) total by 2.04.
The forward is averaging a goal every 166 minutes in all competitions this term, compared to one every 88 minutes for PSG in his last of seven seasons in Paris.
Madrid thrashed Osasuna 4-0 last time out in the league to return to winning ways but still trail leaders Barcelona by six points.
Asked about his connections with Madrid, former Los Blancos basketball player Doncic said: "I follow Real Madrid every time.
"I grew up there. They taught me everything, so it's a part of my life. You can call it a secondary home.
"I learned a lot of stuff there and, especially, they gave me a way to be here right now [in Dallas]. I always appreciate that 100%."
Madrid return to action after the international break with a trip to Leganes on Sunday.
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