Video Assistant Referee (VAR) Lee Mason has left his role "by mutual consent" after his blunder cost Arsenal a win against Brentford last weekend.
The Gunners were held to a 1-1 draw in a London derby last Saturday, though Ivan Toney's equaliser should have been disallowed.
Toney headed in from close range after Christian Norgaard nudged the ball across the face of goal, but the latter had been offside in the build-up.
The goal went to a VAR check for a separate incident instead, with Mason – in charge of the technology for the game – not spotting Norgaard strayed just offside.
The Professional Game Match Officials Limited (PGMOL), the body responsible for referees in England, subsequently acknowledged it was a "significant error" and Mason was not assigned to a match for the coming weekend.
PGMOL then revealed on Friday that Mason has left his position with immediate effect.
A statement read: "PGMOL can confirm that Video Assistant Referee Lee Mason has departed the organisation by mutual consent.
"Lee was a Premier League referee for 15 years and oversaw 287 top-flight matches during that time, with his last coming during the closing stages of the 2021-22 season.
"His full career in the professional game saw the 51-year-old officiate in over 500 fixtures after he progressed to the Football League in 1998.
"We would like to thank Lee for his dedicated service to the professional game and wish him all the best for the future."
It was not Mason's first high-profile error of the season, having denied Newcastle United a winner against Crystal Palace in September when ruling out Tyrick Mitchell's own goal for what he deemed to be a foul by Joe Willock on Vicente Guaita in the build-up.
Frank praises Brentford's pressing, sees no tactical revamp with Toney departure
Thomas Frank heaped praise on Brentford's pressing following their 3-1 victory over Southampton on Saturday.
Bryan Mbeumo scored twice from Brentford's forwards forcing the Southampton backline into errors as the Bees earned their second Premier League win of the season.
This did not go unnoticed by Frank, who believes his side rank as one of the best in the league when it comes to that specific aspect.
He told BBC Sport: "They made errors because we pressed them unbelievably well. I think we are one of the best teams to do the high pressure in the Premier League.
"The players are so committed and that is the reason why we capitalised on errors from Southampton.”
Despite the departure of Ivan Toney to Al-Ahli, Frank does not think their style of play will have to be restructured too much, with both Mbuemo and Yoane Wissa enjoying productive starts to the season in his absence.
Frank said: “Ivan is a fantastic player, I'd love to have him in the team but he has his own journey and is going elsewhere.
"Our style of play hasn't changed. Wissa and Ivan are different players but the style doesn't change.”
Southampton boss Russell Martin was frustrated with his side’s mistakes at crucial moments, believing their performance was far better than the scoreline suggested.
He said to the BBC: “We made two mistakes that we were punished for, which is frustrating and disappointing.
"I saw lots of good things to feel positive about. I feel a lot better this week than I did after the Nottingham Forest game.”
Brentford 3-1 Southampton: Bees begin life after Toney with comfortable win
Brentford began life without Ivan Toney with a comfortable 3-1 victory over Southampton.
Bryan Mbeumo’s brace and a Yoane Wissa goal proved to be the difference between the two sides and condemned the Saints to their third straight loss since promotion back to the Premier League.
With departed striker Toney watching in the stands after his move to Al-Ahli in Saudi Arabia, the hosts proved too strong for Russell Martin’s men. They created the superior chances and capitalised on an error-strewn performance from Southampton’s backline.
Mbeumo opened the scoring on the stroke of half-time before doubling the lead halfway through the second period and Wissa then got on the scoresheet moments later to continue Brentford’s strong start to the campaign. Yukinari Sugawara bagged a consolation in injury time for the Saints.
Brentford sit in fifth place ahead of the first international break, while Southampton are second-bottom of the league table with zero points.
Data debrief: Wissa continues to prove effective at home
Wissa now has five goals and two assists in his last seven matches at the Gtech Community Stadium.
Brentford have recorded consecutive home league wins for the first time since last November, and the first time in their opening home games since August 2018.
Brentford 3-1 Southampton: Bees begin life without Toney with comfortable win
Brentford began life without Ivan Toney with a comfortable 3-1 victory over Southampton.
Bryan Mbeumo’s brace and a Yoane Wissa goal proved to be the difference between the two sides and condemned the Saints to their third straight loss since promotion back to the Premier League.
With departed striker Toney watching in the stands after his move to Al-Ahli in Saudi Arabia, the hosts proved too strong for Russell Martin’s men. They created the superior chances and capitalised on an error-strewn performance from Southampton’s backline.
Mbeumo opened the scoring on the stroke of half-time before doubling the lead halfway through the second period and Wissa then got on the scoresheet moments later to continue Brentford’s strong start to the campaign. Yukinari Sugawara bagged a consolation in injury time for the Saints.
Brentford sit in fifth place ahead of the first international break, while Southampton are second-bottom of the league table with zero points.
Data debrief: Wissa continues to prove effective at home
Wissa now has five goals and two assists in his last seven matches at the Gtech Community Stadium.
Brentford have recorded consecutive home league wins for the first time since last November, and the first time in their opening home games since August 2018.
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