Argentina's World Cup hopes took a shuddering blow in their Qatar 2022 opener as they were sensationally beaten 2-1 by Saudi Arabia.
Having won the Copa America last year and embarked on a 36-match unbeaten run, La Albiceleste arrived in Qatar as one of the favourites to be crowned world champions.
Lionel Messi's penalty gave them an early lead in their first Group C match at Lusail Stadium, but second-half goals from Saleh Al-Shehri and Salem Al-Dawsari ensured Saudi Arabia pulled off a huge upset.
Here, Stats Perform takes a look at five of the other monumental World Cup shocks over the years.
Senegal 1-0 France (Korea/Japan 2002)
Perhaps the all-time upset in World Cup history, France headed to the 2002 edition four years on from a triumph on home soil with a squad brimming with talent and set on defending their crown.
Yet in the opening match, Les Bleus - without talisman Zinedine Zidane - were stunned by Senegal, the competition's lowest-ranked side, thanks to Papa Bouba Diop's first-half finish in Seoul.
France went on to finish bottom of Group A with just a draw against Uruguay to their name, and failing to score a single goal.
North Korea 1-0 Italy (England 1966)
Arriving in Europe for their first appearance at the World Cup, North Korea were widely expected to make an early exit after a defeat to the Soviet Union and a draw with Chile.
But Pak Doo-ik made history when his lone goal saw them shock two-time winners Italy at Ayresome Park in Middlesbrough.
North Korea have only been back to the World Cup once, at South Africa 2010, where they scored once and conceded a dozen, finishing bottom of Group G.
Cameroon 1-0 Argentina (Italy 1990)
This is not the first time La Albiceleste have been involved in one of the most unexpected results at a World Cup, having been stunned in the first match of their title defence over three decades ago.
Argentina arrived at Italia 90 looking to defend the crown Diego Maradona guided them to four years prior, but Francois Omam-Biyik's 67th-minute goal at San Siro left them shell-shocked.
USA 1-0 England (Brazil 1950)
Heading into their tournament debut in South America, England were fancied to make a big impact, particularly when they came up against a United States team dominated by part-timers.
But a goal for Joe Gaetjens made history for the USA, bringing England back down to earth after they started with a 2-0 win over Chile.
Walter Winterbottom's men were then on their way home after slumping to a 1-0 loss at the hands of Spain.
Northern Ireland 1-0 Spain (Spain 1982)
Fondly remembered four decades down the line, Northern Ireland's win against tournament hosts Spain ranks among the greatest in their history, as they defied the odds in Valencia.
Gerry Armstrong's goal early in the second half put then in front and although Mal Donaghy was shown a red card, Billy Bingham's team hung on to deliver an almighty upset.