Simone Inzaghi confirmed Romelu Lukaku will miss Inter's Champions League clash with Bayern Munich due to injury, but should recover before the World Cup.
Inter have already qualified for the knockout stages of UEFA's premier club competition after defeating Viktoria Plzen 4-0 on matchday five in Group C, subsequently eliminating Barcelona.
Belgium international Lukaku scored from the bench in the win over Plzen and was introduced as a substitute in Saturday's 3-0 win over Sampdoria, in which he aggravated a reoccurring left-hamstring injury.
While Inzaghi will be without the on-loan striker at Bayern on Tuesday, he suggested Lukaku should be fit before the World Cup, where Belgium start their campaign against Canada on November 23.
"He had a little problem with his scar [in his hamstring] in Saturday's match when he came on," Inzaghi said.
"There was a statement from the club, he will have to rest for a few days and then he will be re-evaluated at the weekend.
"It is a slowdown that was not needed, he was giving a lot in this period, we hope to be able to use him again before the [World Cup] break."
The trip to Allianz Arena may prove a step too soon for Marcelo Brozovic, too, though Inzaghi suggested the Croatia midfielder will be available for Sunday's crunch Serie A clash against Juventus.
"Brozovic we hope can return on Sunday, then [Danilo] D'Ambrosio is out and we won't have him until after the break," he added.
"We know what game we have on Sunday, I will change something but not too much. Today we did something on the pitch, but not too much. In my opinion the team is giving excellent responses."
Inzaghi hailed an "almost perfect" October after Inter made it seven games without defeat in all competitions, winning six of those, in what has been a transformation of fortunes for the Nerazzurri.
"Compared to September we are in better shape, the conditions of the players have improved," he continued.
"Tomorrow it will not count for the group, but it will be a match in a beautiful stadium, against one of the best in Europe.
"We want to have a serious, organised match, knowing that there will be difficulties, we find a very strong team, with a deep squad."