Romelu Lukaku and Andre-Frank Zambo Anguissa scored in second-half stoppage time as Napoli fought back for a thrilling 2-1 victory over Parma in Serie A.
Newly promoted Parma, who stunned Milan last week, looked set to claim a second surprise win in as many games when Ange-Yoan Bonny won and converted a 19th-minute penalty.
The momentum of the game changed, however, when Parma goalkeeper Zion Suzuki was shown his second yellow card for a foul on David Neres with 15 minutes of the 90 remaining.
With no further substitutions available to the visitors, defender Enrico Del Prato took over in goal and went close to getting his team over the line with a clean sheet intact.
However, new signing Lukaku came off the bench to equalise for Napoli in the second minute of stoppage time, shortly after the Partenopei had seen a penalty overturned following a VAR review.
There was more drama to come at the death as Anguissa headed home in the sixth minute of stoppage time, though Napoli also had to survive one last scare as Pontus Almqvist was denied by Alex Meret at the other end.
Data Debrief: Flying start for Lukaku
Just as Napoli's hopes seemed to be slipping away, up stepped debutant Lukaku to level with a low strike, setting the stage for the most remarkable of comeback victories.
Across the last five Serie A campaigns, Lukaku has 29 goals in 48 home games for Inter, Roma and Napoli. That is the fewest home games required by any player to net over 25 goals in the competition during that span.
Parma, meanwhile, were left to rue the sending-off of Suzuki, who became their first goalkeeper to see red in Serie A since Antonio Mirante against Sassuolo, back in March 2015.