Women's Champions League holders Lyon were humbled by Arsenal as this season's competition began on Wednesday, while Barcelona won by an even greater margin in their opener.
The English side beat their hosts 5-1 at the Groupama Stadium, with Caitlin Foord and Frida Maanum handing Arsenal a 2-0 lead before Melvine Malard halved the deficit.
Foord scored again in between two goals from Ballon d'Or runner-up Beth Mead to give Jonas Eidevall's side an impressive opening victory in Group C.
Barca romped to a 9-0 success against Benfica in Group D thanks to seven different goalscorers.
Asisat Oshoala and Geyse scored two each, while goals also arrived from Patri Guijarro, Aitana Bonmati, Mariona Caldentey, Ana-Maria Crnogorcevic and Claudia Pina as last season's runners-up strolled to victory.
The other game in Group D saw Bayern Munich earn a tougher three points at home to Rosengard after Loreta Kullashi's opener for the visitors was cancelled out by Carolin Simon, before Linda Dallmann struck a second-half winner for the Germans.
Group C's other contest ended with Juventus claiming a 2-0 win at FC Zurich, with late goals from Valentina Cernoia and Barbara Bonansea earning Joe Montemurro's side three points.