Babar Azam's 13th ODI century propelled Pakistan to a dramatic three-wicket victory over South Africa as Temba Bavuma suffered defeat in his first game as limited-overs captain.
Bavuma, who replaced Quinton de Kock as skipper, could only manage one run with the bat at Centurion, but Rassie van der Dussen's unbeaten 123 helped South Africa to 273-6.
Captain Babar (103) struck 17 fours as he went at almost a run a ball, with Pakistan 186-2 when he departed.
However, they lost five further wickets for just 85 runs from there as South Africa threatened an unlikely turnaround, with some impressive death bowling from Andile Phehlukwayo fraying the nerves.
But Faheem Ashraf got Pakistan over the line off the final ball to give them a 1-0 lead in the three-match series.
South Africa were reduced to 55-4 after being put into bat by the tourists, whose early inroads owed to a blitz from Shaheen Shah Afridi (2-61), who removed openers Aiden Markram and De Kock before then catching Bavuma at third man off Mohammad Hasnain.
Van der Dussen's 116-run stand with David Miller (50) gave South Africa's innings momentum, though, with Phehlukwayo sharing a stand of 64 as the Proteas' centurion found crucial support from the lower order.
The impact of that assistance looked to be minimal when Pakistan set about their reply, Babar and opener Imam-ul-Haq (70) combining for 177 to lay the platform.
Mohammad Rizwan and Shadab Khan appeared to have steadied the ship after Anrich Nortje (4-51) accounted for Pakistan's talismen as he ripped through the middle order.
But there was to be great drama in the closing overs. Rizwan holed out to deep midwicket off Phehlukwayo and, when Shadab fell to the same bowler going for the big shot on the first delivery of the final over needing only three off six balls, comeback hopes were very much alive.
Phehlukwayo then produced three successive dot balls but Faheem took advantage of a slower ball and a wide delivery to produce the final three runs as Pakistan survived a nervier conclusion than was necessary.
ECB chief insists no decision made on Mott future
England and Wales Cricket Board chief executive Richard Gould has denied reports a decision has already been made on Matthew Mott's future as white-ball coach.
Mott's future has been called into question in the aftermath of England's failure to defend their T20 World Cup crown in the United States and West Indies, losing to India in the semi-finals.
Mott also oversaw England's calamitous 50-over World Cup campaign last year, as they lost six of their nine matches in India and crashed out in the group stage.
Reports earlier this week suggested the decision had already been made to dispense with Mott's services, with Eoin Morgan a contender to succeed him, though the former limited-overs captain has since said he has no interest in the role.
Asked by BBC Test Match Special if Mott's future had already been decided, Gould said: "That's not true. That's certainly not true.
"Matthew Mott is a really good guy and coach. He's got a great track record and it is the same with [captain] Jos [Buttler].
"We are always assessing options - that is what happens in high-performance sport, you are always assessing your options.
"You never want to be drawn into being given the dreaded vote of confidence or anything like that. Competitive sport always brings scrutiny and decisions.
"We'll constantly want to assess our options but we'll always want to do the right thing by the sport, the team and individuals."
West Indies grab three late wickets on day one as third Test against England in the balance
England lost three wickets in a dramatic end to day one of the third Test against West Indies, leaving them in a precarious position after restricting the tourists for 282.
Gus Atkinson finished with figures of 4-67, while Chris Woakes took 3-69 for England, as only a fine sixth-wicket stand from Jason Holder and Joshua Da Silva saved West Indies from being bowled out for a much lower total.
But England, chasing a 3-0 series whitewash, let their dominant position slip when taking up the bat for the final 35 minutes, Zak Crawley (18), Ben Duckett (3) and Mark Wood (0) being dispatched as bowler Jayden Seales dropped them to 38-3.
Windies skipper Kraigg Brathwaite won the toss and chose to bat, leading his side to a solid start before a spell of three wickets in five overs before lunch put England on top.
Atkinson accounted for Mikyle Louis (26) and Alick Athanaze (2) on either side of Wood sending stumps flying with a full delivery to dismiss Kirk McKenize for 12.
Brathwaite's knock of 61 was brought to a halt shortly after the action resumed, the captain gloving Wood's leg-side ball to Jamie Smith as the tourists slid from 76-0 to 115-5 in 45 balls.
Holder (59) and Da Silva (49) then shared 108 to drag the Windies towards a respectable total, but things looked bleak for them when the latter feathered Woakes' ball through to Smith.
Having gone 30 overs without a wicket, England needed just 14 more to polish off the tail, the highlight being a terrific diving catch from Joe Root to send Gudakesh Motie (8) packing.
England were given just over half an hour with the bat to cap Friday's action, but any hopes of a serene finish were soon dashed.
Holder made two terrific catches off Seales' bowling, the first from Crawley's thick outside edge and the second to dismiss Wood for a duck, either side of Alzarri Joseph's cracking delivery accounting for Duckett.
That spell ensured what had been a good day for the hosts ended on a sour note, with the Windies sure to target quick wickets when the action resumes on Saturday.
Data Debrief: Atkinson and Seales dominate
This series began with all the focus on James Anderson as England's greatest-ever bowler bowed out at Lord's, but Atkinson has taken centre-stage since making his Test debut in the opening match and now has 20 wickets through five innings.
That is eight more than West Indies' Jayden Seales, the next-most prolific bowler in this series, has managed.
Seales was determined to have an impact on day one, though, and his two wickets at the death have set the stage for a far more competitive match than those England won at Lord's and Trent Bridge.
Bairstow set sights on swift England Test return
Jonny Bairstow bit back when asked if he was targeting an England return, insisting it is "all I want to do."
Bairstow was dropped from England's Test team for the ongoing series against West Indies.
The 34-year-old was part of England's T20 World Cup squad, and played in all five Tests of the tour of India earlier this year.
Bairstow has made 100 Test appearances, and when asked what his immediate target was, the wicketkeeper-batsman told former England captain and now-BBC Sport pundit Michael Vaughan: "All I want to do is play for England. That's end of.
"You don't need to ask me that do you? I think you know me well enough and I think you've known me for long enough to know that."
Bairstow did, however, enjoy a break away from the game, having had four weeks off before he joined the Welsh Fire for the Hundred.
He said: "At the same time it's been a great period of time.
"I had the best part of seven months away from home. Since January, I had five nights at home in my own bed since, until three weeks ago.
"That's the thing you have to sacrifice, time at home but at the same time, when you are away for that period of time, it takes its toll."
England are 2-0 up against the Windies in their three-match series, with the final Test starting at Edgbaston on Friday.
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