After adding the French Open title to the Australian Open that he won in January, Nadal is halfway to a possible calendar grand slam of all four majors.
That was last achieved in men's singles in 1969, when Australian great Rod Laver carried off the full set.
Nadal received injections before every match at Roland Garros to effectively send his troublesome left foot to sleep and curb pain, and he will have radiofrequency treatment in a bid to ensure he can go in search of a third major title of the year at the All England Club.
The 36-year-old Spaniard hopes to be able to be in London when Wimbledon starts on June 27, and having won there in 2008 and 2010, he will believe in his chances of a third slam on grass.
Former world number four Henman told Eurosport: "If Nadal is healthy, which is a big challenge now with this foot injury, can he win Wimbledon? Absolutely. So I think that's incredibly exciting."
Nadal now has 14 French Opens among his 22 grand slams, a men's record, and is two clear of Roger Federer and Novak Djokovic who share second place on the all-time majors list.
Federer might be finished as a force at the top level, although he appears ready to give it one more shot later in the year, while Djokovic will likely start as favourite for Wimbledon glory, regardless of Nadal's recent feats.
"In terms of who's going to end up with the most grand slams, a couple of years ago I would have said Djokovic, for sure," said Henman, a perennial British favourite at Wimbledon who reached four semi-finals there. He now sits on the board of the All England Club, the tournament hosts.
"Right now, with that little bit of distance, I think Nadal has got a great chance. It's going to be fascinating to see. You've got another opportunity in three weeks' time, so fingers crossed, I so hope Nadal can be there on grass."
Wimbledon was cancelled this year for the first time since World War II due to the coronavirus pandemic.
Murray was said to be nearing a return from a hip injury, having last played at the Davis Cup Finals in 2019.
Henman feels the break could be beneficial for two-time Wimbledon champion Murray, who turns 33 in May.
"He has missed so much tennis but perhaps [the break] will give him the opportunity – if his body and his hip enable him – to play longer, in age terms," he told UK media, via The Guardian.
"I remember playing with Agassi after Andre had 18 months out, for very different reasons, but he came back fresh and invigorated to play. He kept going until he was 36.
"In those days that was old for a top tennis player. I stopped when I was 33 and that was pretty old at the time, but with training techniques and injury prevention, players are certainly playing longer.
"You would like to think that if Andy's body permits and he still has the motivation that I think he does there can still definitely be a few Wimbledons left in him yet."
A player who appears closer to the end of his career is Roger Federer, with the 20-time grand slam champion turning 39 this year.
Henman – an All England Lawn Tennis and Croquet Club (AELTC) board member – said the Swiss great, who underwent knee surgery in February, would be shattered by the cancellation of Wimbledon.
"Someone like Federer, coming to the end of his career, is devastated but understands the decision," said Henman, a four-time Wimbledon semi-finalist.
"It will affect a lot of people in a lot of different ways."
The 18-year-old achieved stunning success at the US Open, winning the grand slam event as a qualifier without dropping a set.
Raducanu will play her first match since that famous Flushing Meadows triumph when she takes on Aliaksandra Sasnovich at the Indian Wells Open on Friday.
The youngster has been rated as favourite to win the tournament, which is seen as one of the most prestigious outside of the four majors.
There is already talk of her qualifying for the lucrative season-ending WTA Finals and triumphing at Wimbledon next year, having burst onto the scene in 2021 by reaching round four at All England Club.
But fellow Briton Henman urged fans to show caution with what they expect from Raducanu before her first match in 27 days against seasoned pro Sasnovich.
Raducanu has regularly discussed her lack of experience at tour level while she searches for a new coach to show her the ropes and Henman did not want to entertain discussions of her winning Wimbledon in 2022.
"I think that is probably getting a little ahead of ourselves," Henman said to talkSPORT.
"She has shown her enormous potential by what she did in New York, but she is still so young and so inexperienced.
"She has played so few events on the tour, let alone at grand slam level. I think it’s very easy to get ahead of ourselves.
"Regarding some of the young up and coming players, to really understand where they are at and their development, for me you get a very good insight once they have played every tournament twice.
"To put it into context, she has never played the clay court swing, she’s never played Roland Garros, she has never played the Australian Open.
"Once she has played all those events twice, then we will be able to assess where her game is at.
"Right now, it is as much about the process as the outcome and keep developing her game."
Henman, though, was in no doubt that Raducanu is a prodigious talent.
He added: "What is exciting is that she can improve in so many areas.
"It is easy to focus on her tennis game, but she can get fitter, stronger, faster and gain experience playing at the highest level and continue improving her tennis game.
"If she does that then I think she will go on and win more tournaments in the future.
"It was a privilege to be on the side of the court for all her main draw matches and just see the quality of her tennis at close quarters.
"Her resilience mentally, her composure and the consistency was incredible. To win 20 straight sets to qualify and win a grand slam is unprecedented in our sport, it was a real pleasure to watch."
While Raducanu received a first-round bye, Sasnovich had an easy opener as she beat Maria Camila Osorio Serrano in straight sets.
The Belarusian has never won a WTA Tour event or reached the last eight of a major.
