The last American to win the men's singles crown at any grand slam was Andy Roddick at the 2003 US Open.
The USA is still way out in front for all-time grand slam men's singles titles with 147, though 19 years and counting is comfortably their worst barren spell during the Open Era.
This comes after 2003 was the 15th year in a row that the USA had at least one champion in the men's majors, with the likes of Pete Sampras and Andre Agassi both prolific winners.
Of course, the drought did not extend to the women, with Serena Williams, Venus Williams, Sloane Stephens and Sofia Kenin all winning at least once since Roddick's success at Flushing Meadows.
But with eight of the last 32 in the men's draw representing the USA, there is a renewed sense of optimism – and that is even accounting for their highest seed, number eight Taylor Fritz, falling in the second round.
Gauff – who beat compatriot Bernarda Pera on Friday – is the USA's next great female hope, and she is looking forward to the day Americans claim a men's and women's double at the same slam.
Asked if there was a refreshing sense of excitement around the men, Gauff said: "Yeah, definitely. I definitely think on the men's side they're thriving.
"It's like eight people in the round of 32 I saw. I think it's incredible. It's just people that you've been rooting for for a long time, and some new faces, too, that people probably haven't been rooting for a long time but fell in love with.
"I'm just excited. On the women's side, we're always like, 'the guys need to catch up, you guys need to put in your work'. I think they're here. I'm hoping that eventually, hopefully soon, we'll have our slam champion on the men's side.
"That would be pretty cool if an American woman and guy could win the same slam. I don't know when the last time that's happened or if it's ever happened. I'll be pretty excited."
Coincidentally, it last happened at Melbourne Park. In 2003, Andre Agassi and Serena Williams were victorious at the Australian Open.
Gauff is not getting carried away, but her perception is there is genuine belief among the men now, which is being fed by unity.
"I definitely think the guys are feeling it," she said. "You can see it. I think it really comes from, not the women, but the same dynamic, where everybody is doing well, so it makes you want to do well.
"We're all not competing with each other but pushing each other. I think that's what the men are having.
"They're competing against each other but also pushing each other to be better. I'm pretty sure all the American guys get along, at least that's what I think."
There were setbacks to American men's title hopes on Friday as Frances Tiafoe and Mackenzie McDonald both lost at the last-32 stage, but there was a hugely notable win too, with Sebastian Korda beating seventh seed, two-time Australian Open runner-up and former US Open champion Daniil Medvedev in straight sets.
Federer, who has not played competitively since exiting Wimbledon at the quarter-final stage last year, revealed on Thursday that next week's Laver Cup will be his farewell tournament.
Federer appeared at a parade of former champions at Wimbledon earlier this year and hinted at his desire to feature at the All England Club once more, but his upcoming outing in London will now represent the swansong to his stunning career.
The Swiss great will become the first of the ATP Tour's 'Big Three' to exit the sport, with Rafael Nadal and Novak Djokovic still active.
While Nadal and Djokovic have each surpassed Federer's tally of 20 major titles this year, the 41-year-old overtook Pete Sampras' previous record of 14 grand slam titles by beating Roddick in the 2009 Wimbledon final.
Roddick was among the first to pay tribute to Federer's achievements on Thursday, writing on Twitter: "Cheers Roger. Thanks for the shared memories my friend.
"It was an honour to share time/experiences on the most hallowed grounds in our sport. Don't be a stranger."
Alcaraz, who clinched his first grand slam title and became world number one with a US Open final win over Casper Ruud on Sunday, simply wrote: "Roger…", accompanied by a heartbroken emoji.
Milos Raonic has seen his efforts to win a major title foiled by the presence of the 'Big Four' – with Andy Murray beating him on his sole grand slam final appearance at Wimbledon in 2016 – but he also showed his appreciation for Federer's impact.
"Thank you for doing more for tennis than any single individual," Raonic wrote. "Thanks to you competitors and fans across the world get to experience and enjoy it all over the world.
"Congratulations on your achievements and the people you continue to impact in and away from tennis."
Juan Martin del Potro, who prevented Federer from winning six consecutive US Open titles with a five-set success in the 2009 final, labelled the 41-year-old irreplaceable, declaring: "I LOVE YOU, Roger.
"Thank you for everything you've done in tennis and with myself. [The] tennis world will never be the same without you."
Former player-turned presenter James Blake added: "Roger, there was and never will be anyone like you. You crushed me on the court, but were so nice and genuine that I couldn't hate you for it.
"You made the game better on and off the court and you will be missed. Good luck, you have earned all the success and joy in the world."
Garbine Muguruza tweeted: "RF" followed by a heartbroken emoji.
Those who shared a court with Federer were not the only ones to pay tribute, however.
A tweet from Wimbledon's official account read: "Roger, where do we begin? It's been a privilege to witness your journey and see you become a champion in every sense of the word. We will so miss the sight of you gracing our courts, but all we can say for now is thank you, for the memories and joy you have given to so many."
Roland Garros' official account tweeted: "An inspiration on and off the court. Thank you, Roger."
The US Open's handle simply posted: "Thank you, Roger."
Raducanu was beaten by Katerina Siniakova in her first match in Miami this week after being given a bye into the second round.
She has won only four WTA Tour matches since sensationally becoming the first qualifier – male or female – to win a major in the Open Era at Flushing Meadows in September.
The 19-year-old has been in demand off the court, having last week announced she will be a brand ambassador for Porsche, but her business activities have attracted criticism.
Speaking after Raducanu's defeat to Siniakova, former world number five Daniela Hantuchova claimed the Briton has lost the locker room respect she had previously built up.
Kim Clijsters took aim at those who act as though they have "made it", meanwhile, though the four-time major winner did not mention Raducanu by name when making those comments.
Raducanu defended herself from the "unfair" accusations and Kyrgios has now questioned why former players have felt the need to take aim at the youngster.
"What’s with old retired players giving their opinion on our stars now?" he posted on Twitter, referencing a video uploaded by Andy Roddick on how players can curtail their anger.
"I love A-rod and I agree we all need to chill with the rackets and all that, but geezus.
"I read an article about a past female player talking about Radacanu, no offence, but she is a far, far bigger name already."
Tiafoe surged into the world's top 10 in June after winning the Stuttgart Open, Tiafoe achieving a career-high ranking after his triumph in Germany.
Wimbledon will be the next challenge in Tiafoe's sights, with the 25-year-old looking to build upon his last-four appearance at the 2022 US Open – his best finish in one of the four majors.
Evenden oversaw Tiafoe's his first ATP title in 2018 before the pair parted ways three years later, and he sees no reason why the American cannot go all the way to glory.
Speaking to Stats Perform at the inaugural Tennis Black List at the LTA National Tennis Centre, Evenden said: "We worked together for four years and every day he stressed me out, but it was because I knew this was waiting at the end of the road and I know he's got much further to go.
"I think it's only a matter of time before he now figures out a way to get to the top five and then hopefully it's only a matter of time before that slam comes."
Asked whether Tiafoe had the ability to go all the way in a major, Evenden added: "Undoubtedly. That's no doubt, it's just a matter of when for me. I've never doubted that from him for a minute."
Evenden, who was replaced by former top-10 player Wayne Ferreira in 2021, believes Tiafoe's technique is perfectly suited for Wimbledon, where he faces Yibing Wu in his opening round on Tuesday.
He continued: "That quick whip take-back, short, compact backhand. He has got all the touch and all the feel.
"I think he's got so much potential on the grass. I've always thought that and I think that this year, we could see something special from him."
Pete Sampras won Wimbledon seven times across his illustrious career, while Andre Agassi triumphed once in SW19. Andy Roddick, meanwhile, reached three finals at the All England Club, and Evenden is confident Tiafoe can deal with the pressure of being compared to his compatriots.
"As with everyone, it takes a while for you to come to terms with the pressure and come to terms with the success too because it's hard winning because you got to sacrifice so much," he said.
"Someone with such a personality like him, he's got to sacrifice more than other players. I think he deals with it very well.
"I think he's taken some huge steps in dealing with it and figuring out what works for him and what he needs to do. Obviously, he loves to show up at the big events. I think he's only going to get better."
America has not had a male grand slam singles winner since Roddick triumphed at the US Open back in 2003.
Djokovic – bidding to become only the third man to claim a calendar Grand Slam and first since Rod Laver in 1969 – rallied from a set down to prevail 1-6 6-3 6-2 6-2 en route to the quarter-finals in New York on Monday.
It was a brutal clash on Arthur Ashe Stadium, 20-time major champion and top seed Djokovic needed almost three hours to see off world number 99 Brooksby, who was making his debut at the iconic venue.
After being blitzed in a 29-minute opening set, Djokovic and Brooksby contested a gruelling 20-minute fifth game in the second set – the latter converting a sixth break-point chance.
Djokovic's physical superiority, however, was on display as the Serb star eventually powered past the spirited 20-year-old at Flushing Meadows.
During the last-16 matchup, former world number one Andy Roddick tweeted, in reference to Djokovic, "first he takes your legs… then he takes your soul".
Djokovic – who will face sixth seed Matteo Berrettini in a repeat of the Wimbledon final – said on court: "Thanks Andy, I take that as a compliment – only the first part.
"The second part, I don't take anybody's soul. Everyone has their soul, we're all beautiful souls so I appreciate everyone. But I'll take your legs out, that's for sure."
Djokovic hit 44 winners in the four-set triumph, to go with 41 unforced errors in a tricky clash under the Arthur Ashe lights.
With his hard-fought victory, Djokovic improved to 11-0 against Americans at the US Open. He is 29-3 at major events and 70-10 in ATP Tour-level matches.
The 34-year-old is on a 21-match winning streak against players from the United States since Sam Querrey snapped his 30-match slam streak at Wimbledon in 2016.
"Great quality match," Djokovic, who can break the record for most men's slam titles – currently level with injured pair Rafael Nadal and Roger Federer, told reporters. "He started off better. I've never played him. I didn't see him play too many times. Maybe few matches in the last few months. Haven't followed his career prior to that, so I didn't know much about him. Had to do some homework and some analysis.
"It's different stepping out on the court first time against someone that really has nothing to lose. He's a young, talented player that is very crafty. He's got the really all-around game. He was pumped. He had the crowd behind him, of course. He played a perfect first set. Everything he intended to do he executed it perfectly.
"On my end, I was just trying to find a rhythm, trying to read his game, trying to understand where I can find holes in his game and start to attack and shift the momentum to my side.
"That happened already at the beginning of the second set. I broke him early. He broke back. But I re-broke his serve right away. We had some very, very long rallies, long games. It took a toll physically I think on both of us at that point. But I managed to find the right serves. I served efficiently when I needed to, opening up the court.
"The third and fourth set were really, really good from my side. I felt I was more dominant. I decreased the unforced errors that were really high in the first part of the match. I just was kind of swinging through the ball better. Was a good finish. It wasn't a good start. But all in all, expected the battle, and I got that one. I'm pleased to overcome it."
