Cristiano Ronaldo has emerged as an injury doubt for the Premier League match between Manchester United and West Ham on Saturday.

The Portugal star played 71 minutes of the 3-1 win at Brentford on Wednesday before being substituted - a decision with which he was clearly annoyed.

Interim manager Ralf Rangnick insisted he had no problem with the player becoming frustrated at going off and that it would not affect his chances of facing the Hammers at Old Trafford.

However, Rangnick later confirmed Ronaldo suffered a neck injury during the victory over Brentford that could keep him out of the game.

"Cristiano is a question mark because he has a problem with his neck," he said to MUTV on Friday.

"He received treatment yesterday [Thursday] for two, three hours and we will have to wait to see how he feels today."

Edinson Cavani missed the match at Brentford Community Stadium and he too is facing a race to be fit for the visit of David Moyes' men.

"Edi hasn't been training with the team yet and will hopefully resume training today and then we'll take the final decision after the training session, [around] if he will be available for the game," Rangnick said.

Losing Ronaldo and Cavani presents United with a possible striker shortage given Anthony Martial is attempting to secure a move away from the club.

Rangnick left Martial out of the 2-2 draw at Aston Villa, saying the France international had told him he did not want to be involved – a claim Martial later disputed.

Jesse Lingard will be available to face the club for whom he excelled on loan last season, while Jadon Sancho, who missed the Brentford match due to a family funeral, could be involved.

"We need to see where Jadon stands," said Rangnick. "He didn't train yesterday. As you know, he attended a funeral on Wednesday and didn't want to train yesterday as he is still affected by that. We will have to see.

"I will see him for training today and speak with him after the training session, to see if he is in the state of mind, and also his energy [is there], so he can be available for tomorrow."

Aaron Wan-Bissaka will also be missing again with illness, while Victor Lindelof will sit out the game after a burglary of his family home, but midfielder Scott McTominay hopes to be involved after battling a back problem.

Not many would have predicted before the season that Manchester United versus West Ham represented a key game in the battle for the top four, but that's where we are.

The Red Devils' win over Brentford moved them to within two points of the Hammers in fourth, with a game in hand, meaning Saturday's clash at Old Trafford offers a good chance to make some headway in the race to finish behind Chelsea, Liverpool and Manchester City.

It also gives David Moyes the chance to end a pretty rotten record at the home of his old club – and that's not including the nine months he was in charge there – as well as the chance for West Ham to avenge their defeat in the reverse fixture.

Let's not forget they have already won away against United in 2021-22 – and not many teams manage to do that twice in a season. The last one, in fact, was managed by Jose Mourinho.

BEDEVILLED

United have won 20 of their 25 home games against West Ham in the Premier League, their last defeat coming in May 2007, when soon-to-be Red Devil Carlos Tevez secured a 1-0 win for the visitors.

Yet their record when London clubs come calling hasn't been so strong of late: they have lost three of the previous eight home games against teams from the capital, as many such defeats as they suffered in 38 matches at Old Trafford between 2013-14 and 2019-20.

West Ham, of course, boast the rare feat of being above United in the table: while they sit fourth, United are seventh. Only four times previously in the Premier League era have the Hammers faced them while being placed higher in the standings; interestingly, they failed to win any of them, losing 2-1 in August 1995 and September 2014, drawing 0-0 in August 1998 and losing 3-1 in December 2020.

'PLAY LIKE FERGIE'S BOYS...'

Moyes has done a quite brilliant job at West Ham since being parachuted in to rescue them in December 2019. Since the start of 2020-21, he has managed 30 wins from 60 league matches, accruing 102 points in that time. The only sides with more victories and more points are United, Chelsea, Liverpool and Manchester City.

Old Trafford, though, is not a happy hunting ground for the former United boss. He has drawn four and lost 10 of his away games at the stadium as a Premier League manager; only Harry Redknapp (15 games) has visited more often in the competition without a single win.

That being said, Moyes did lead West Ham to victory on this ground in the EFL Cup back in September, and they could become just the fourth team to beat United away twice in the same season after Aston Villa (1919-20), Tottenham (1989-90) and Chelsea (2004-05).

BOWEN'S ROAD RAGE, HAMMER TIME FOR RONALDO

Cristiano Ronaldo scored in United's dramatic 2-1 win in the reverse fixture in September, in which he was also denied a couple of pretty strong penalty shouts before Mark Noble's injury-time spot-kick was saved by David de Gea.

The Portugal great has always quite enjoyed facing the Hammers, with six goals and one assist in his five league appearances against them. He was directly involved in seven of the 10 United goals in those matches, in fact, so you wouldn't bet against him keeping up that record – assuming, of course, he isn't having a strop on the bench instead.

Jarrod Bowen, arguably West Ham's most in-form player, is another who will be hoping to make an impact.

He has scored six and assisted seven goals in his past 18 league appearances, including goals in his most recent two, but the former Hull City man has only scored three times in 43 top-flight matches on the road, converting a meagre four per cent of his shots (3/69).

Bowen has played seven times against United from the start, but he's never scored, and only twice has he even lasted the whole game.

SATURDAY SLUMP

It's a minor novelty in itself that United are playing a match at 15:00 local time on a Saturday. Such is their global appeal that broadcasters are usually quick to shift them to a more viewer-friendly kick-off time.

Ralf Rangnick might actually have preferred a different slot. United have lost their most recent two games to start at this time on a Saturday, both of which were this season: 4-2 at Leicester City, and 4-1 at Watford, a result that ended the reign of Ole Gunnar Solskjaer. Never before have they lost three in a row when playing at this time.

United's opening league game of 2022 ended in a 1-0 loss to Wolves at Old Trafford. They have not lost their first two home league matches in a year since 1985, when Ron Atkinson's side were beaten by Sheffield Wednesday and Coventry City. They did go on to finish fourth, though...

Ralf Rangnick insisted that his priority will always be with the Manchester United team and not certain individuals amid ongoing questions over Cristiano Ronaldo's behaviour at Brentford.

United sit seventh in the Premier League but are two points behind fourth-placed West Ham with a game in hand after defeating Brentford 3-1 on Wednesday.

Ronaldo played a part in Mason Greenwood's goal, the second for United, at the Brentford Community Stadium but was removed nine minutes later, seemingly much to the Portugal captain's disgust.

The 36-year-old appeared annoyed as he wandered towards the dugout, where he sat on the steps as he continued to gesture as if he was asking why he had been substituted.

Rangnick, who could be seen having a word in Ronaldo's ear minutes later in an attempt to defuse the situation, said post-match that the commotion did not concern him, a stance he once again reiterated on Friday.

"I think we shouldn't make too much of a fuss out of it," Rangnick responded when asked about Ronaldo at a pre-match news conference ahead of Saturday's clash with West Ham.

"I can only speak for myself and my coaching staff. I explained that to him during the game, we had a little conversation after we scored the third goal. In fact, I told him the same as what I said in our press conference. 

"The job of a football manager is to help the team win the game and it was clear from our experience at Villa Park that this time we have to do things better. 

"We did it better and the only question was, who do we take off? Of course, Cristiano is a prolific goalscorer and he's a player that will always want to play and score goals. 

"The team is more important than whoever – Cristiano, Edinson [Cavani], Bruno [Fernandes].

"He was also asking why me 'why didn't you take off one of the younger players?'. The answer came five minutes later when one of the younger players scored the third goal. 

"Maybe Cristiano could have also scored the third goal, but football is not about maybe, it is about taking a decision in the right moment."

Asked for further clarification on his decision to send on centre-back Harry Maguire for Ronaldo, Rangnick added: "In a way in football it's a bit like chess, things can change so quickly during the game. 

"If you watched last night's semi-final [between Arsenal and Liverpool] in the EFL Cup things can change from one minute to another.

"In some parts of the game, you are dominating the game, pinning the other team back, and all of sudden it can be different. 

"Therefore it is important to be able to react to what the game needs now, to what the team needs and we had exactly the same decision at Brentford as at Villa, 70 minutes played, 2-0 up against a team who does not give up. 

"For me, it was logical with the negative experience we had at Villa Park to do it differently this time and it was clear we bring on Harry [Maguire] and then defend this 2-0 result and in the end we even scored a third one on the counter-attack and it was clear we were going to win the game."

Ronaldo will likely lead the line again at home to David Moyes' Champions League-chasing Hammers, who the striker has scored seven goals in his last five top-flight appearances against.

West Ham, however, have already won away at Old Trafford this season, winning 1-0 in the EFL Cup. Only three teams have ever won twice away against the Red Devils in the same season – Aston Villa (1919-20), Tottenham Hotspur (1989-90) and Chelsea (2004-05).

Rangnick appreciates he has to take a game at a time at the United helm as he refused to look to far ahead in terms of rebuilding at the club.

"My full focus as I have indicated is to win games with this team, in order to win games as a team we need to develop as a team," he continued.

"We need to improve in some areas, we have done so in the last couple of weeks, but there is still more space for that in vast areas of our game and this is where my focus is. 

"I'm not dealing with what might happen in four or five months, that is not on top of my list.

"It's about how we can win the game against West Ham, then the cup against Middlesbrough and then Burnley, playing Southampton and Brighton [and Hove Albion] at home, this is where my focus is."

Cristiano Ronaldo's dream homecoming to Manchester United has not gone quite to plan so far.

While Ronaldo has scored 14 goals in 22 games – double the amount of any other United player – his team have otherwise struggled this term.

And with United in a serious battle to qualify for next season's Champions League, an early parting of the ways could be on the cards.

TOP STORY – RONALDO'S TOP-FOUR ULTIMATUM

Ronaldo's representatives have informed United that the superstar forward will leave if the club miss out on a top-four finish in the Premier League, according to The Sun.

The Portugal international, who penned a two-year contract in August with the option of a further year, is said to be concerned by the direction in which United are heading.

Ralf Rangnick's side beat Brentford 3-1 on Tuesday but still remain seventh, albeit now just two points off fourth-placed West Ham with a game in hand.

Serial winner Ronaldo last week questioned the attitude of some of his United team-mates and then reacted angrily to being substituted off during the win at Brentford.

ROUND-UP

– Bayern Munich will consider selling Robert Lewandowski at the end of the season if their talisman turns down the offer of a new deal, according to Bild. Lewandowski, who received The Best FIFA Men's Player of the Year on Monday, is out of contract at the end of 2022-23.

– Goal reports that Atletico Madrid have no intention of allowing Luis Suarez to complete a sensational return to the Premier League this month. The former Liverpool striker had been touted as a target for Aston Villa, who are now under the management of his old team-mate Steven Gerrard.

– Chelsea have set their sights on a trio of Barcelona players, reports El Nacional. Blues boss Thomas Tuchel is said to be particularly keen on Frenkie de Jong, while full-back Sergino Dest and youngster Gavi are also targets.

– Meanwhile, Sport say that Barca are interested in Chelsea's Andreas Christensen. Barca are hoping to reach a pre-contract agreement with the defender this month.

– Newcastle United must fend off competition from another Premier League club for the signing of Sevilla centre-back Diego Carlos, claims Sky Sports. The Magpies are also reported to be interested in Jesse Lingard.

– Arsenal striker Pierre-Emerick Aubameyang is the subject of a loan bid, with an obligation to buy, from Saudi Arabian club Al-Nassr. The Gabon international is out of the picture under Mikel Arteta and may be granted permission to leave for the rest of 2021-22. Goal are reporting that story.

Ralf Rangnick was not overly concerned about Cristiano Ronaldo's reaction to being substituted in Manchester United's 3-1 win at Brentford.

United claimed their first Premier League victory of 2022 on Wednesday, with Anthony Elanga, Mason Greenwood and Marcus Rashford getting the goals before a late Ivan Toney consolation.

The visitors were fortunate to not trail at the break but produced a hugely improved display in the second half, with Ronaldo playing a part in Greenwood's goal as he chested the ball into Bruno Fernandes' path before he squared to the 20-year-old.

Greenwood and Ronaldo were withdrawn nine minutes later, with Rashford and Harry Maguire entering the pitch as Rangnick changed to a back five.

Ronaldo appeared annoyed as he headed off and that displeasure continued to emanate after sitting in the dugout, the striker seen seemingly asking Darren Fletcher why they had chosen to withdraw him.

In the aftermath of Rashford's goal, Rangnick could be seen having a word in Ronaldo's ear, the situation appearing to be defused.

"It's normal, as a striker he wants to score goals," Rangnick told BT Sport before going on to explain his decision.

"He came back from a little injury, so for me, it was also important to bear in mind we also have another game in three days' time.

"On the other hand, we were 2-0 up, the same score as at Villa Park, and I decided to make sure we defended that lead this time and I think it was the right decision to switch to a back five.

"We scored the third goal, we would have wanted to keep the clean sheet but unfortunately we didn't manage that, but at least we made sure nothing more happened."

United were indebted to David de Gea's performance as he made seven saves over the course of the match, increasing his season total to 81 – 11 more than any other Premier League goalkeeper.

The Spaniard's form has been exceptional this season, with his 6.2 'goals prevented' being the best figure among keepers in the top flight.

Rangnick acknowledged United fell well short of expectations in the first half, before paying tribute to De Gea's brilliant form.

Asked if he had to get tough at half-time, Rangnick said: "I wouldn't say a strong conversation [was had] but obviously we had to change a few things.

"In the first half we were not good in almost all aspects of the game: sloppy passing, not strong enough in the 50:50 situations, we gave away almost every second ball.

"Then in the second half we were more urgent, attacking them higher up the pitch and making the right decisions when on the counter, and we scored – this was the big difference."

On De Gea's display, he added: "He's been doing that for the last couple of weeks. Brilliant saves in the first half, [he's] one of the best goalkeepers in the world right now I'd say."

Victory for United moved them on to 35 points, level with Arsenal in sixth, though the Gunners have played one match less.

Mason Greenwood and Marcus Rashford ended personal goal droughts with second-half strikes as Manchester United put wasteful Brentford to the sword in a 3-1 Premier League win on Wednesday.

Ralf Rangnick's men threw away a two-goal lead away to Aston Villa on Sunday but they managed to avoid repeating the feat in what was their first league meeting with Brentford since 1947.

United were indebted to David de Gea – and Brentford's unimpressive finishing – in a first half that the home side largely dominated, but the Red Devils improved significantly after the interval.

Two goals seven minutes apart left Brentford deflated and Rashford added to their misery, with Ivan Toney's late strike a mere consolation.

Amid an early Brentford flurry, De Gea crucially got a boot to Mathias Jensen's 13th-minute effort, Vitaly Janelt and Mads Bech Sorensen then saw efforts deflected just wide before Christian Norgaard inexplicably volleyed over from close range.

United – who did not record a single first-half shot on target – had De Gea to thank again after the half-hour mark, the Spaniard blocking Jensen's goal-bound attempt.

The breakthrough ultimately came at the other end with 55 minutes on the clock – Anthony Elanga latched on to Fred's lofted pass into the danger area and nodded past Jonas Lossl after flicking the ball up for himself.

Greenwood then scored his first Premier League goal since October, tapping in from Bruno Fernandes' squared pass after being released by Cristiano Ronaldo's clever chested pass.

Ronaldo fumed at his withdrawal soon after for Rashford, but the England striker finished off a flowing move late on to justify his introduction with his first strike since October 30.

Toney prodded home from close range to force a tense finish but United saw it out.

Cristiano Ronaldo returned to Manchester United's starting line-up for their trip to Brentford after missing the past two games through injury. 

The Portugal captain has scored 14 times in 21 appearances this term but has not featured for Ralf Rangnick's side since a 1-0 home loss against Wolves on January 3, having suffered a minor injury setback. 

The former Real Madrid man led the United attack – replacing Edinson Cavani – in west London on Wednesday, though, with Bruno Fernandes slotting in behind his countryman as captain. 

Rangnick also handed another start to youngster Anthony Elanga, who was utilised from the outset against Aston Villa last Saturday, while Mason Greenwood was deployed on the opposite flank. 

Scott McTominay was Rangnick's only other change from the Villa game as he returned from a one-game suspension to replace Nemanja Matic in midfield. 

Club captain Harry Maguire was still only fit enough for the bench after suffering from an abdominal injury, meaning Victor Lindelof partnered Raphael Varane in the United defence again. 

Cristiano Ronaldo "cannot do things on his own" and Manchester United will therefore not look to build their team around one player, according to interim manager Ralf Rangnick.

The Portugal international has scored 14 goals and assisted three more in 21 appearances since returning to Old Trafford from Juventus in September.

That is double the number of goals than any other United player, with compatriot Bruno Fernandes next on the list with seven strikes to his name in 2021-22.

Ronaldo's incredible longevity was recognised with a special award from FIFA on Monday after becoming the all-time top goalscorer in men's international football history in 2021.

But while Rangnick is in awe of Ronaldo's scoring record, he has no plans to centre his United side around the five-time Ballon d'Or winner.

"What he has done with his career so far is amazing: 800 goals in competitive games, which no one has achieved that in the last 80 or 100 years," Rangnick said.

"That shows what kind of exceptional player he is. But the Premier League is the most competitive league in the world and he cannot do things on his own. 

"He is one important member of this team and that’s how we have to develop."

Ronaldo has missed United's last two games – a 1-0 win over Aston Villa in the FA Cup third round and a 2-2 draw against the same side five days later in the Premier League.

Rangnick is hopeful of having Ronaldo back for Wednesday's trip to Brentford, which has been rescheduled from last month after a COVID-19 outbreak in the United camp.

A raft of games have been called off in the English top flight in recent weeks, with bottom side Burnley having as many as four games in hand on some sides around them.

Thomas Tuchel is among those to have asked for more transparency in terms of games being called off, with Chelsea recently having a postponement request declined. 

Asked if he feels more should be done to prevent postponements, Rangnick said: "I don't know, I can only speak about our club here, we had some problems four weeks ago.

"Right now we don't have any issues, we have players available, we haven't had any COVID cases. I can't judge other clubs, it's something the Premier League has to deal with."

United head to Brentford sitting seventh in the Premier League and with just one win from their last five away top-flight matches. 

The Red Devils have scored in all 10 of their Premier League away games this season, which is the best-such 100 per cent record in the competition this term. 

However, three of the last four times they have failed to find the net on the road in the league have been in games in London (v Arsenal, Chelsea and Crystal Palace last season).

Nick Kyrgios compared the crowd during his Australian Open first-round win to a zoo as fans copied a famous Cristiano Ronaldo celebration at almost every point.

Cries of 'siuu' could be heard throughout much of the home favourite's straight-sets victory over Liam Broady, his first match since a Laver Cup defeat to Stefanos Tsitsipas in September.

The shouts were apparently mimicking Manchester United star Cristiano Ronaldo's famous goal celebration.

There were similar incidents during Andy Murray's battling five-set win over Nikoloz Basilashvili, as the five-time finalist won his first match at the Melbourne major since 2017.

The raucous crowds caused confusion as many observers wondered if Murray and Kyrgios were being booed on court, despite each player also enjoying huge support.

Kyrgios later explained he was not surprised to hear the noise from the stands but was taken aback by how long they persisted.

"It's just a stupid, f***, I can't believe they did it so much," he said after his 6-4 6-4 6-3 victory on John Cain Arena. "They were doing some Ronaldo thing. Ronaldo does it every time he scores.

"It's like... I thought they were going to do it for like 10 minutes. They did it for two and a half hours, like, every point. I don't know why. It was a zoo out there."

Murray had wondered if the crowd was turning on him during his epic 6-1 3-6 6-4 6-7 (5-7) 6-4 victory because he had been targeted during his practice session on Monday.

"Initially, I thought it was [booing] because there were some people booing during my practice yesterday," he said. "I have no idea what for! 

"But then, after a few times, it was like, no, they're doing that, I think it's like 'Siuu' or something that Ronaldo does when he scores. And, yeah, it was incredibly irritating!"

Kyrgios produced some superb if often unorthodox tennis as he booked a second-round clash with world number two Daniil Medvedev, who is the highest-ranked male in the draw following the refusal to allow Novak Djokovic to compete.

The 26-year-old would like to return to John Cain to aid his chances of improving his record against the Russian to 3-0.

"It's going to be a hell of an experience for me," he said. "He's probably 'the' best player in the world at the moment. So I'm pretty excited, I'm excited for that moment. That's why I play the game.

"I feel like those matches still excite me, to go out there and play the best in the world. That was always something I wanted to prove to people that someone like me could do, win those matches.

"I'm not going to go into it with a lot of expectation. I'm going to go out there, have some fun, play my game. I have a pretty set-in-stone game plan of what I need to do to have success.

"As I said, he's probably the best player in the world, he does everything extremely well. He's a hard worker, ticks all the boxes. I'm not going to even think about that now. To play it on John Cain would be – I'm just going to call it the Kyrgios Court – would be fun."

Cristiano Ronaldo has said he hopes to play for another "four or five years" despite turning 37 next month.

The Manchester United forward received the FIFA Best Special Award at a ceremony in Zurich on Monday in recognition of breaking the world record for international goals in September last year previously held by Iran's Ali Daei (109), with Ronaldo now on 115 goals for Portugal.

When asked by event co-host Jermaine Jenas about his "obsession" with the game and where it could take him, Ronaldo said he still has the same love for football as he did when he was younger, and gave an idea as to how long he intends to keep playing.

"I still have the passion for the game. Not just to score goals," Ronaldo said. "It's to entertain myself, because I have played football since I was five, six years old.

"When I go to the pitch, even in training, I still enjoy [it] and my motivation is still there. Even [though] I'm going to be 37 soon, I feel good, I feel motivated.

"I keep working hard, since 18 years old, and I continue. I love the game, I still have that passion and I want to continue.

"People ask me sometimes how many years more I am going to play, and I say I hope to play four or five years more.

"It's all about mentally, because I think physically if you treat your body good, when you need your body, it will give it back to you, so this is what I do."

Ronaldo has scored 14 goals in 22 games for United in all competitions since making a dramatic return to Old Trafford at the start of the current season, but recently indicated frustration at the recent form of the team.

The Red Devils currently sit seventh in the Premier League table, five points off fourth-placed West Ham and 24 points behind top of the table Manchester City, though with two games in hand over both.

Talking to Sky Sports last week, the former Real Madrid and Juventus marksman said: "I don't accept that our mentality be less than being in the top three in the Premier League.

"I think to build up good things, sometimes you have to destroy a few things. So why not – new year, new life and I hope that we can be the level that the fans want. They deserve that.

"We are capable of changing things now. I know the way but I'm not going to mention it here because I don't think it's ethical on my part to say that.

"What I can say is we can do better – all of us. Manchester United belongs to important things, so we have to change that.

"I don't want to be here to be in sixth place, or seventh place, or fifth place. I'm here to try to win, to compete.

"I think we compete but we are not yet in our best level. But we have a long way to improve and I believe if we change our mind, we can achieve big things."

The FIFA Best Awards were conducted on Monday, with Chelsea taking three prizes.

While Robert Lewandowski and Alexia Putellas, who won the women's Ballon d'Or last year, took home the prizes for Best Men's and Women's player respectively, the Blues had winners in the form of Thomas Tuchel, Emma Hayes and Edouard Mendy.

Tuchel, who guided Chelsea to Champions League success last season, scooped the Best Men's Coach award, while Hayes was named Best Women's Coach.

Hayes' team won the Women's FA Cup and Premier League in 2020-21, while also finishing as runners-up in the Women's Champions League to Barcelona, who Putellas plays for.

Mendy, meanwhile, won the Best Men's Goalkeeper award. However, he did not make the Men's XI, with Italy and Paris Saint-Germain shot-stopper Gianluigi Donnarumma preferred.

Tuchel's triumph also means that a German coach has won the Men's award for the last three years, after Jurgen Klopp in 2020 and 2019.

The Denmark national team won the Fair Play Award for their actions in helping to save Christian Eriksen's life after the midfielder collapsed on the pitch in Copenhagen at Euro 2020.

Erik Lamela won the Puskas Award for his incredible rabona finish in the north London derby.

Cristiano Ronaldo, meanwhile, was given a Special Award for his career achievements.

FIFA Best Awards 2021 winners:

Robert Lewandowski (Best Men's Player)
Thomas Tuchel (Best Men's Coach)
Edouard Mendy (Best Men's Goalkeeper)
Alexia Putellas (Best Women's Player)
Emma Hayes (Best Women's Coach)
Christiane Endler (Best Women's Goalkeeper)
Denmark men's national team (FIFA Fair Play Award)
Erik Lamela (Puskas Award)
Denmark and Finland fans (FIFA Fan Award)
Cristiano Ronaldo (FIFA Special Award)
Christine Sinclair (FIFA Special Award)

Cristiano Ronaldo and Marcus Rashford were notable absentees from Manchester United's squad for Saturday's clash with Aston Villa.

Ronaldo missed the FA Cup third-round tie between the sides on Monday due to injury and the 36-year-old was not fit enough to feature at Villa Park, despite Ralf Rangnick's hopes on Friday that he would have the striker available.

Harry Maguire and Jadon Sancho missed United's 1-0 victory over Villa, but both returned to United's bench for the Premier League clash.

However, there was no place among the substitutes for England international Rashford, who endured a difficult night at Old Trafford at the start of the week and has struggled for form all season.

The forward has netted just two Premier League goals in 11 appearances this term, starting only seven times in the top flight.

With Ronaldo and Rashford absent, and Anthony Martial not in the picture, Anthony Elanga was handed a full league debut, with Edinson Cavani leading the line.

Villa boss Steven Gerrard, meanwhile, handed a debut to new signing Lucas Digne, who arrived in a reported £25million deal from Everton in the week.

Gerrard's other new acquisition – his former Liverpool team-mate Philippe Coutinho – took a place on Villa's bench.

Manchester United interim manager Ralf Rangnick has urged his players to follow the lead of Cristiano Ronaldo and be more direct with one another.

Ronaldo called for United fans to have patience with Rangnick's approach in a recent interview with Sky Sports, and said he and his team-mates "can do better".

The 36-year-old added that he does not want to be "in sixth place or seventh place" and that he returned to the club "to try to win, to compete."

United have only lost one of Rangnick's seven matches in charge across all competitions, but recent performances have received criticism from fans and pundits alike, including Monday's 1-0 FA Cup win against Aston Villa at Old Trafford.

Speaking at a news conference ahead of Saturday's trip to Villa in the Premier League, Rangnick said he was pleased to hear Ronaldo's words, and said he hopes the rest of his players can show the same attitude.

"We have so many top, talented players," he told reporters. "It brings me back to what Cristiano said – we have to work and develop as a team together and if it's necessary to speak in a very direct manner to the boys, it helps a lot, even in the locker room.

"If Cristiano, for example, or any of the other players address that to the players directly on the pitch or in the dressing room, they are more than welcome to do that.

"I will do that myself as a coach – and my coaching staff in the pre-and-post match video – but we can only develop individual players if we develop the performances of the team.

"It's not only Cristiano, we have Edinson [Cavani], we have Harry [Maguire], we have quite a few other older players, David de Gea in goal, Victor Lindelof, Bruno [Fernandes]. 

"We have enough experienced older players who can not only be role models in training, on the pitch and in games, but also in all those conversations that happen in the locker room or when they are together in the hotel for away games or home games. This has to happen.

"In a united team, that happens automatically, and I can only invite and challenge and tell all the players, also the older players, to do that on a regular basis because that helps even more so in a team that we have currently."

The Red Devils currently sit seventh in the Premier League, 22 points behind leaders Manchester City and six behind West Ham in fourth place, but with two games in hand over both.

Ralf Rangnick has told Dean Henderson and Donny van de Beek to sit tight and wait for their chances to come at Manchester United.

The United interim boss, who expects to have Cristiano Ronaldo and Harry Maguire back for Saturday's Premier League match at Aston Villa, knows Henderson and Van de Beek have been considering leaving Old Trafford.

Speaking in a news conference on Friday, Rangnick made the case that goalkeeper Henderson and midfielder Van de Beek can be useful assets for the Red Devils over the closing months of the season.

He described Henderson as a "fantastic" shot-stopper, but recognised he wanted Premier League game time that cannot be guaranteed at United. The Englishman has played just twice for United this term, neither appearance coming in the league.

Rangnick also knows Van de Beek is hungry for first-team football for the sake of his Netherlands career, with the World Cup coming up in Qatar at the end of the year.

Addressing Henderson's situation initially, Rangnick said: "I told him that I would like him to stay because he's a fantastic goalkeeper. In training yesterday, he had another couple of fantastic saves.

"I really like to have him on board, as one of three top goalkeepers. I can fully understand that he wants to play because he's in an age where, as a goalkeeper, he should regularly play.

"On the other hand, we are still in three competitions, we need the three goalkeepers we have right now. I told him that, but I can also, on the other hand, understand his desire to get game-time elsewhere in the Premier League."

David de Gea has reasserted himself as United's first choice between the posts, after Henderson played 13 Premier League games last season, while the other senior goalkeeper on United's books is third-choice Tom Heaton.

Henderson was not involved in the FA Cup clash with Villa on Monday, when United took a nervy 1-0 win in the third round. De Gea started that game and Heaton was the substitute goalkeeper, with Rangnick saying it was illness that kept Henderson out of the game.

Van de Beek came off the bench in the 72nd minute to strengthen a midfield that was being over-run.

The former Ajax man could be practically assured of regular involvement at another club, but at United he has been used just seven times in the Premier League this term. All those appearances have been as a substitute, with Van de Beek spending a meagre total of 68 minutes on the pitch.

"It's the same situation as it is with Dean," said Rangnick. "I'm glad to have him in the squad."

The former RB Leipzig boss said he spoke to Van de Beek after training two weeks ago.

"I told him I would advise him to stay until the end of the season. He wants to play in the World Cup for his country and [Netherlands coach] Louis van Gaal obviously told him that in order to be a regular starter for the World Cup, he needs to regularly play for his team," Rangnick said.

"I can understand his desire to play; on the other hand, we have a lot of competition in our squad in exactly those positions."

United were without Maguire and Ronaldo for the cup clash with Villa, so to have them back adds experience and quality at each end of the pitch, albeit with neither man having been at the height of his powers in recent weeks.

Across his career, Ronaldo has been involved in 11 goals in nine Premier League starts against Villa (eight goals, three assists). That is the most goals he has scored (eight) and been involved in (11) against a specific opponent in the competition.

Jadon Sancho and Phil Jones should also be up for selection after being absent for the FA Cup game.

"I think they will be available," Rangnick said of his quartet. "They only trained yesterday for the first time, Cristiano yesterday, Harry the day before yesterday.

"We have to wait for the final session this afternoon but as it seems right now, they should be available for tomorrow."

While the signs are positive there, United will be hampered by one-match suspensions for Luke Shaw and Scott McTominay that rule both out of the Villa Park game.

Villa have not won any of their last 22 home league games against United (D7 L15) since a 3-1 victory in August 1995. That ranks as the longest winless home run any side has had against another in English Football League and Premier League history, according to Opta.

However, Villa scored a 1-0 win at Old Trafford in September, with Bruno Fernandes missing a last-gasp penalty, and will be attempting to win consecutive league games against United for the first time since November 1976.

They last did the league double over the Red Devils in 1954-55. A United win would be their 300th away from home in the Premier League, making them the first side to reach that mark.

Cristiano Ronaldo is confident Ralf Rangnick will do a "good job" as interim manager, but the Portugal forward will not accept Manchester United aiming for anything less than third place.

Rangnick's appointment – until the end of the season before taking on a consultancy role – was initially praised as evidence United were attempting to modernise as a club, implementing a brand of football and identity that has been so successful elsewhere.

The German had been deemed the so-called "godfather of gegenpressing" and was seen by many as a shrewd hire given his reputation of developing clubs in the past both as a coach and a director.

But, even though United have only lost one of his seven matches in charge across all competitions, their performances have left a lot to be desired, and the idea of a collective and concerted pressing effort appears to remain foreign.

Prior to Rangnick's first game, United averaged 7.6 high turnovers per game in the Premier League – in his first two matches they recorded 12 and 11, respectively.

A trend emerged there, as the only occasion this season United had previously recorded more than 12 (13) was in Michael Carrick's first match against Chelsea. It would seem to be the classic 'new manager bounce' as they soon fell back into their old ways.

United's high turnover average under Rangnick in the league remains virtually identical (7.6) to what it was before, while they managed just three in Monday's fortunate 1-0 FA Cup win over Aston Villa, suggesting his ideas in that regard simply are not getting across.

But Ronaldo is calling for patience, telling Sky Sports: "Since he arrived five weeks ago, he changed many things. But he needs time to put his ideas across to the players.

"It takes time, but I believe that he is going to do a good job. We know we aren't playing the best football, but we have many games to improve.

"Since he arrived I think in some points we are better, but he needs time. It's not that easy to change the mentality of players and the way they play, the culture, the system like that. I believe that he is going to do a good job.

"We have to be together. We're in the same boat. We have to believe that it is possible but like I said we have a long way to go."

United face Villa again on Saturday in the Premier League – a victory could potentially see them end the weekend three points behind fourth-placed West Ham, who have played two extra games.

Missing out on the top four would be a major blow to United given the amount of money spent in pre-season, though Ronaldo feels even fourth would be unacceptable.

Asked if they can reach the top four even without the correct attitude, Ronaldo said: "Impossible – I think it's the main point.

"I don't accept that our mentality be less than being in the top three in the Premier League.

"I think to build up good things, sometimes you have to destroy a few things. So why not – new year, new life and I hope that we can be the level that the fans want. They deserve that.

"We are capable of changing things now. I know the way but I'm not going to mention it here because I don't think it's ethical on my part to say that.

"What I can say is we can do better – all of us. Manchester United belongs to important things, so we have to change that.

"I don't want to be here to be in sixth place, or seventh place, or fifth place. I'm here to try to win, to compete.

"I think we compete but we are not yet in our best level. But we have a long way to improve and I believe if we change our mind, we can achieve big things."