Marnus Labuschagne will miss Australia's white-ball tour of West Indies in July due to travel complications amid the ongoing coronavirus pandemic.
Labuschagne is currently playing for Glamorgan in England's County Championship and Australia's selectors have decided it will be more practical for the batsman to remain in the UK.
Australia will play five T20s in St Lucia and three ODIs in Barbados.
Although Labuschagne has not represented his country in the shortest format, he has three fifties and a century in 12 ODI innings, at an average of 39.41.
"Anyone who knows Marnus understands he would give absolutely anything to play for Australia and he is deeply upset to miss out due to circumstances beyond anyone's control," Australia's selection chairman Trevor Hohns said.
"We worked through numerous options in conversations with Marnus to find a workable solution but ultimately came to the conclusion it was more practical for him to remain in the UK.
"Had we not been in the middle of a global pandemic, Marnus would be on this tour as a well-established member and important part of the one-day side.
"It's an unfortunate circumstance of the many challenges the world is facing right now. As it stands, Marnus has the opportunity to continue in county cricket and T20 games with Glamorgan as we head into the [T20] World Cup and home summer."
Daniel Sams asked to be left out of the tour, which could yet be followed by a limited-overs trip to Bangladesh, for personal and mental health reasons.
The all-rounder tested positive for COVID-19 during his recent stint in the Indian Premier League, which was subsequently postponed due to the worsening coronavirus situation in the country.
Cricket Australia's integrity unit has contacted Cameron Bancroft to ask whether he wishes to provide any new information over the 2018 ball-tampering scandal that saw himself, Steve Smith and David Warner banned.
In an interview with The Guardian on Saturday, Bancroft hinted Australia's bowlers during that Test match against South Africa at Newlands – who were not punished – knew about activities undertaken to illegally alter the condition of the ball.
"Yeah, obviously what I did benefits bowlers and the awareness around that, probably, is self-explanatory," he said.
Preliminary Australia squad for limited-overs tour of the West Indies:
Aaron Finch (captain), David Warner, D'Arcy Short, Steven Smith, Josh Philippe, Alex Cary, Matthew Wade, Glenn Maxwell, Marcus Stoinis, Moises Henriques, Mitchell Marsh, Ashton Agar, Adam Zampa, Mitchell Swepson, Tanveer Sangha, Pat Cummins, Mitchell Starc, Jason Behrendorff, Josh Hazlewood, Riley Meredith, Jhye Richardson, Kane Richardson, Andrew Tye