Wales boss Warren Gatland has made seven changes to the starting line-up for Saturday’s Guinness Six Nations clash against England at Twickenham.

Centre George North returns from injury for his 50th Six Nations appearances, lining up alongside Nick Tompkins in midfield.

Fly-half Sam Costelow, who went off injured during the first-half of Wales’ 27-26 loss to Scotland last weekend, is replaced by Ioan Lloyd, with Tomos Williams at scrum-half.

Gatland has also selected a new front-row of Gareth Thomas, Elliot Dee and Keiron Assiratti, with Cardiff flanker Alex Mann handed a first Wales start following his try-scoring appearance off the bench against Scotland.