Ilya Ivashka earned a meeting with Stefanos Tsitsipas at the Mallorca Championships, while Alex de Minaur got his Eastbourne International defence up and running with a straight-sets win on Monday.

A comfortable 6-4 6-1 victory over Emil Ruusuvuori sent Ivashka into the second round, where world number six Tsitsipas awaits after receiving a bye.

Mallorca third seed Denis Shapovalov will face Benjamin Bonzi who benefited as Alejandro Tabilo retired while trailing 6-3 4-2 to the Frenchman.

Roberto Bautista Agut overcame Taro Daniel 6-4 7-6 (7-4) to advance, while Antoine Bellier defeated Federico Delbonis 6-3 7-6 (8-6) and Feliciano Lopez fell to a 7-6 (7-3) 7-6 (7-3) loss to Tallon Griekspoor.

De Minaur took an hour and 23 minutes to get past Cristian Garin 6-3 6-3 for a strong start in his bid to retain the trophy in Eastbourne.

The Australian will either face compatriot James Duckworth or Lorenzo Sonego, who he defeated in the final last year, in round two.

Fifth seed Reilly Opelka fell to a 6-3 6-1 defeat against tournament debutant Maxime Cressy, while Alexander Bublik was three points away from losing to Frances Tiafoe before rallying back to win 5-7 7-6 (7-4) 6-0.

Bublik will face John Millman next after the Australian overcame Sebastian Korda 6-3 7-6 (7-5), while top seed Cameron Norrie awaits Brandon Nakashima and Diego Schwartzman is next in line for Jack Draper.

Korda withdrew from Wimbledon after the defeat to Millman, the 21-year-old American saying on Twitter he was suffering with "terrible shin splints and beaten up feet" and needed a rest.

Top seed Casper Ruud suffered a shock first-round exit at the Queen's Club Championships, going down in straight sets to British ATP Tour debutant Ryan Peniston in west London.

The French Open runner-up struggled to get going as he fell to a 7-6 (7-4) 7-6 (7-2) defeat to the world number 180, who was backed by a boisterous home crowd throughout.

Ruud struggled from the off as Peniston forced four break points in the Norwegian's first service game, and his miserable outing was rounded off when his opponent raced into a 5-1 lead before serving out a second-set tie-break.

After claiming the scalp of the world number five, Peniston told the BBC: "I can't really believe it. It feels like a dream. It doesn't feel real.

"I think I've been playing well. Casper is an unreal player and he did so well at the French Open, so I knew it was a tough ask. Four or five years ago I was sitting in the crowd just watching so to be here now is just unreal."

Ruud was not the only big name to fall at the first hurdle, with fifth seed Diego Schwartzman going down 6-1 6-4 against big-serving Sam Querrey to become the fourth of the top five seeds to fail to reach the round of 16.

Second seed and defending champion Matteo Berrettini is the exception after faring much better against another home favourite, cruising past Dan Evans 6-3 6-3, while Stan Wawrinka downed Francis Tiafoe 7-6 (7-2) 6-7 (6-8) 7-6 (7-5), and Denis Shapovalov's clash with Tommy Paul was suspended by darkness at one set apiece. 

Elsewhere, world number six Stefanos Tsitsipas progressed through his opening match at the Halle Open, beating Benjamin Bonzi 7-6 (7-1) 1-6 6-3 to set up an enticing last-16 clash with Nick Kyrgios, who bested Daniel Altmaier 6-3 7-5.

Fourth seed Felix Auger-Aliassime also progressed after being taken to three sets, beating Marcos Giron 6-3 5-7 6-3.

Meanwhile, defending champion Ugo Humbert will face a tough round-of-16 match against fifth seed Hubert Hurkacz after the Pole overcame Maxime Cressy 6-4 4-6 6-4. 

Andy Murray claimed his first win over a top-five opponent since 2016 as he stunned Stefanos Tsitsipas to reach the Stuttgart Open semi-finals.

Murray started his preparations for the grass-court swing with a run to the semi-finals of the challenger at Surbiton.

He knocked off seventh seed Alexander Bublik to reach the last eight in Stuttgart but a meeting with the top seed and world number five represented a much more imposing challenge.

It was one the two-time Wimbledon champion rose to emphatically, winning a first-set tie-break and then claiming the second set in comfortable fashion to cement a 7-6 (7-4) 6-3 win, gaining revenge for his contentious five-set defeat to the Greek at last year's US Open.

Murray's previous win over a top-five opponent came in the ATP Finals six years ago, when he defeated Novak Djokovic in a year that also saw him win Wimbledon.

"I thought I did well. He served unbelievably in the first set," Murray said in his on-court interview.

"I felt like I had very few chances, but when he was creating chances on my serve, I stayed strong.

"I played a really solid tie-break and in the second set, once I was in the rallies, I felt like I was dictating a lot of the points. It was a good performance."

Murray is up to 53rd in the live ATP rankings and is bidding to get back into the top 50 for the first time since 2018. 

Standing between him and a place in the final is Nick Kyrgios, who was 7-6 (7-3) 3-0 up when Marton Fucsovics retired from their quarter-final clash.

Matteo Berrettini beat Lorenzo Sonego in three sets, while Oscar Otte won by walkover against Benjamin Bonzi.

At the Rosmalen Grass Court Championships in 's-Hertogenbosch, Daniil Medvedev saw off Ilya Ivashka 7-6 (10-8) 6-4.

Medvedev, who will soon return to world number one when the ranking points from the French Open come into effect, sees the grass-court season as a chance to cement his grip on that spot.

"I don't have many points to defend on grass and I have some to win, so hopefully I can play well, starting here," said Medvedev. "Every round is points and the higher you get, the more you need to step up."

He will face defending champion Adrian Mannarino in the semi-finals, while second seed Felix Auger-Aliassime is into a last-four clash with home hope Tim van Rijthoven after beating Karen Khachanov. 

Stefanos Tsitsipas branded his performance against Holger Rune "ridiculous", admitting he allowed his frustrations to get the better of him on court during his shock last-16 exit at the French Open.

Having finished as runner-up at Roland Garros last year, the fourth seed crashed out in the fourth round this time around, going down 7-5 3-6 6-3 6-4 to the Danish teenager, who had only managed one previous win over a top-five opponent. 

The three-hour contest began with Tsitsipas earning an early break, but the Greek went on to struggle against the 19-year-old, who became the first Danish player to reach a grand slam quarter-final during the open era.

Speaking during his post-match press conference, a visibly emotional Tsitsipas admitted he struggled to apply enough pressure on Rune, highlighting his own lack of rhythm on court.

"Great match from his side, but I have to say it was a very bad management from my side," he said.

"I was struggling a lot the last couple of days in terms of finding my rhythm. I was very nervous on the court, being frustrated a lot, and I knew I was this way, but I couldn't stop being like this.

"I was a completely different player once I stepped into the court, taking returns [too] early.

"I think we could see that in the last two service games of his, I was really able to apply a lot of pressure; it was day and night, pretty much, that transformation.

"I just, you know, didn't have my mind completely there when I had to make those changes. It came way too late on in that match, way too late.

"I wasn't really applying a lot of pressure, it was ridiculous at a point, and again I was stubborn, I was stubborn to change it. I need to adjust way quicker, it's too late for this stuff."

Tsitsipas, who squandered a two-set lead in his 2021 final defeat to Novak Djokovic in the French capital, had been tipped by many to repeat his run to the final after landing on the opposite side of the draw to pre-tournament favourites Djokovic, Rafael Nadal and Carlos Alcaraz.

But the Greek refuted suggestions the pressure that comes with a supposedly kinder draw had hindered his performances, telling reporters: "Absolutely not. I don't watch draws, I don't watch my next opponents. 

"I pretty much know the progress and the way I need to do things in order to get to where I was last year, and that doesn't come easy, for sure.

"Of course, I knew I'm going to have to play difficult opponents that know how to play on this surface, but mentally, physically, tennis-wise, I felt good.

"It's just that I had a few troubles in practice. Again, back to frustration, back to not understanding certain things and certain patterns that I was trying to impose.

"He [Rune] is a very emotional player, he can play great, he absolutely deserves this victory, [he] played better, faced tough moments better. But I can see something different next time with this opponent. I'm pretty convinced I can do way better.

"This is not where I've maxed out, let's say. I didn't give myself the opportunity to max out. I didn't give myself the opportunity to go all the way and that is a shame."

Stefanos Tsitsipas is out of the French Open after being beaten by Danish teenager Holger Rune in the fourth round on Monday.

Tsitsipas earned an early break, but things soon started to unravel as he lost the first set.

The Greek number four seed came back to even things up in the second, but had no answer for Rune's power and precision as his opponent won in four sets, 7-5 3-6 6-3 6-4.

Rune - earning just his second ever win over a top five opponent - is the first Danish men's player to reach the quarter-finals of a Grand Slam in the Open Era.

The contest lasted just over three hours on Court Philippe-Chatrier, and Rune thanked the crowd for the part they played.

"I have an unbelievable feeling right now," the 19-year-old said in his on-court interview. "I was so nervous at the end but the crowd was amazing for me the whole match, the whole tournament.

"I am so grateful and so happy to be playing on this court. You guys are amazing.

"I was very nervous but I know at the same time that if I go away from my tactics against a player like Tsitsipas I am going to lose for sure.

"I told myself just to keep at it and play my plan in the tough moments. It worked out so well in the end and gave me a huge confidence boost. It is just so great to still be here."

Rune will play Norwegian Casper Ruud in the quarter-finals after the number eight seed beat 12th seed Hubert Hurkacz earlier on Monday.

Stefanos Tsitsipas said the consistency of his rivals has pushed him to become a better athlete after he eased into the French Open's last-16 with a 6-2 6-2 6-1 win over Mikael Ymer.

Having fought back from two sets down to beat Lorenzo Musetti in the first round before downing Zdenek Kolar in an absorbing four-set contest featuring three tie-breaks, the Greek enjoyed a more routine outing against the 23-year-old Swede.

Fourth seed Tsitsipas, who finished as runner-up at Roland Garros in 2021 after squandering a two-set final lead against Novak Djokovic, has been tipped for a serious tilt at a first Grand Slam title after landing on the opposite side of the draw to many of the pre-tournament favourites.

The world number four cannot meet any of Djokovic, Rafael Nadal, or Carlos Alcaraz until the final, seemingly giving him a shot of atoning for his final disappointment last year.

After storming to a dominant win over Ymer, the 23-year-old said the excellence of tennis' fellow leading lights has motivated him to change his lifestyle to further his chances of success.  

"Well, I will tell you that I respect a lot the top three for having been so incredibly consistent the last couple of years," he told a post-match press conference.

"I have questioned myself, how do I become a better athlete? These guys have pushed me to become a better athlete. 

"I question myself, really, what can I add to my life that can eventually help me achieve more and do more, and do better in terms of my career. So, every day is a question: What can I add?

"Looking back on the diet that I had, let's say, three or four years ago, it's nothing compared to what I have now. In terms of fitness, this is something that I have questioned a lot, as well.

"And, of course, the balance between life and career. It hasn't been easy, but I kind of feel in better control of my life right now, being focused and having control around me without relying too much on other people's feelings."

Tsitsipas was only on court for an hour and 32 minutes in his third round win, and was pleased with making quicker progress than had been the case in his previous outings at the tournament.

"I had to do my job. I had to play my tennis. I wasn't really thinking of the ease that I could maybe create in terms of a result," he added.

"But with my good efforts, the way I committed myself to every single point individually, the end was good. I was able to create a good result today with some good tennis

"It's a good thing to have a match like this every now and then, I think. It was a good performance in ways."

Stefanos Tsitsipas called Zdenek Kolar a "complete player", despite ultimately defeating his Czech opponent in the second round of the French Open.

Tsitsipas was relatively untroubled in the first set, but was made to work for the win after that as he and Kolar exchanged one tie-break each before the number four seed finally secured victory with another tie-break in the fourth set, sealing it 6-3 7-6 (10-8) 6-7 (3-7) 7-6 (9-7).

Kolar is ranked 134th in the world but looked every bit a threat to Tsitsipas on Court Suzanne-Lenglen, hitting 57 winners and succeeding with 29 of 37 net points (78 per cent).

Speaking at a news conference after his win, Tsitsipas explained the difficulties he experienced, saying: "He's someone I knew a little bit. It's never easy playing guys that don't really play on the ATP Tour. You don't really know what to expect. I guess they play more free.

"It's always like this. They really have a nothing-to-lose mentality. It's a different mentality than what we have, I think, which sometimes can really be brutal on the court and create some good tennis.

"He was really pushing a lot today, getting after every ball. His body was behind every ball. Running fast, reacting fast. Good net game. Complete player, I would say. Yeah, it wasn't easy out there to face him and come up with some good solutions."

Tsitsipas - who hit 25 aces - displayed some of his oft-seen frustration as he struggled to stay on top of his opponent, and was asked if his hardest obstacle was Kolar or himself.

"I guess both today," he said. "I had a lot of opportunities, break points, playing quite well, staying within the game. He was coming up with some really good ideas and I think dealt with all of the situations so maturely, not overexaggerating anything. He's an intelligent player, I would say.

"Look, last year there were moments where it was about me and the way I deal with situations on the court, not focusing that much on who is on the other side. It's all about perspective. It's sometimes good to focus on what you are doing, but also if you're not feeling great, you have to see the other side too."

Having rallied from two sets down to beat Lorenzo Musetti in the first round, and now being made to work hard by Kolar, Tsitsipas will now face Mikael Ymer after the Swede beat 29th seed Dan Evans on Thursday.

Stefanos Tsitsipas completed the third comeback win from two sets down of his career on Tuesday, defeating Lorenzo Musetti 5-7 4-6 6-2 6-3 6-2 at the French Open.

Before moving to a 2-0 head-to-head record over Musetti, the fourth-seed Greek's last such victory was against Rafael Nadal in the quarter-finals at the 2021 Australian Open.

Tsitsipas needed to draw on that experience and dig deep after only winning 60 per cent of points on his first serve in the first two sets on Tuesday, going on to then win 15 of 17 points in the deciding set.

Post-match, the world number four explained how he needed to isolate his focus on each point and build from there after going two sets down.

"Things don't come easy. I refuse to give up. That's simply how it works with me," Tsitsipas said. "You never really think about getting back after being two sets to love. You just play it point after point. You just wish that your efforts will pay off on a longer scale, longer run.

"Being in that situation, it's a mountain that you have to climb, and I was able to climb it and regain the momentum steadily, but consistently."

The 20-year-old Musetti was able to gain early momentum from the baseline and won the longer points, with an even share of winners as well as forced and unforced errors from Tsitsipas.

The match turned as Tsitsipas regained rhythm on his serve and with more free points coming his way, it then allowed him to apply pressure.

According to Tsitsipas, however, it was far from easy against a tough opponent who is at home on clay.

"He's fighting. He's a talented player that has a very nice one-handed backhand," he said afterwards. "He knows the game on clay. He has grown up playing these courts. He's definitely a difficult opponent to face in any circumstance, really.

"Once I really found my momentum on the serve, my routines and everything, I knew that it can be a different match. 

"I felt like I was serving better than him, creating more opportunities with my serve, pressing more. It would have been kind of not fair from my perspective to have a different outcome."

Novak Djokovic, Rafael Nadal and Carlos Alcaraz are all on the same half of the draw at the French Open, while women's world number one Iga Swiatek will face a qualifier in the first round at Roland Garros.

Djokovic, who will make his Grand Slam return having missed the Australian Open, opens in Paris against Yoshihito Nishioka, while record 21-time grand slam winner Nadal meets Australia's Jordan Thompson.

The veteran pair of Djokovic and Nadal could challenge each other in the quarter-finals in the top half of the draw, where Alcaraz could come across world number three Alexander Zverev.

Alcaraz faces a qualifier in the first round and has won 16 of his last 17 matches, with the one blemish on his remarkable run coming against Sebastian Korda, who the Spaniard could meet in the third round.

Daniil Medvedev will have to get past Argentine Facundo Bagnis in the first round, while Lorenzo Musetti stands in the way of last year's runner-up Stefanos Tsitsipas.

Medvedev and Tsitsipas are joined in the wide-open bottom half of the draw by Casper Ruud and Andrey Rublev, who meet home favourite Jo-Wilfried Tsonga and South Korea's Soonwoo Kwon respectively.

In the women's draw, 2020 champion Swiatek comes in as favourite and will look to continue her 28-match winning streak when she faces a qualifier in the first round, as does US Open winner Emma Raducanu.

The Brit will then take on Aliaksandra Sasnovich or Wang Xinyu before a potential last-16 meeting with Ons Jabeur, who first has to get past Poland's Magda Linette.

Meanwhile, Karolina Pliskova – who has a first-round clash with France's Tessah Andrianjafitrimo – could set up a quarter-final meeting with Swiatek, but the Pole may have to get past Simona Halep in the fourth round first.

Defending champion Barbora Krejcikova starts against Diane Parry, while Naomi Osaka was drawn against the in-form Amanda Anisimova, who beat the Japanese in the third round of the Australian Open.

Novak Djokovic became the oldest winner of the Internazionali d'Italia men's singles title in the Open Era as he fended off Stefanos Tsitsipas on the clay in Rome.

The world number one said he played a "perfect set" to race through the opener, before coming from a break down in the second to earn a 6-0 7-6 (7-5) victory in Sunday's final.

Djokovic made it a record-extending 38th Masters 1000 title in what was his 55th final at this level, and it was his sixth triumph at this event in the Italian capital.

At 34 years, 11 months and 23 days old, Djokovic is 10 days older than the previous oldest Rome champion, Rafael Nadal, who took the title last year.

He boosted his head-to-head record to 7-2 against Greek star Tsitsipas, winning their last six matches and all five they have contested on clay, including last year's French Open final where Djokovic came from two sets behind to scoop the grand slam. This victory clearly augurs well for Djokovic's upcoming title defence in Paris.

Djokovic broke serve to love in the opening game, Tsitsipas swatting a volley into the net to hand over the early advantage and set the tone for a wildly one-sided set.

Tsitsipas broke to lead 3-1 in the second set and he served for it at 5-3 but was broken to 15, sending a forehand wide on game point. The tie-break that soon followed was hard fought, with Tsitsipas looping a backhand long on match point as Serbian Djokovic earned the trophy once again.

Reflecting on his fast start, and his first title of 2022, Djokovic said on Amazon Prime: "I pleasantly surprised myself, I can say, even though I had a clear game plan and strategy coming into the match. I knew what to expect from the other side so I knew what I had to do, but I did play a perfect set, no doubt about it.

"After that it was a little bit tight, the beginning of the second for me. He used it, and at this level one or two points can turn a match around and he was back in the game. At 4-1 up for him and 30-40, the match could have easily gone into a third set, but I somehow managed to find the right shots at the right time to come back in the game, and the tie-breaker, I guess I was just an inch better, maybe calmer, and it was a tight tie-break for both of us."

Ahead of the French Open, which gets under way next Sunday, Djokovic is feeling in great shape for his title defence. Having missed the Australian Open in January in a deportation drama, Djokovic will head to Paris as a major rival to teenage sensation Carlos Alcaraz.

Should Djokovic triumph at Roland Garros, he would match Nadal's men's record of 21 grand slams.

"I've been building my form in the last couple of weeks and like the previous years I knew that my best shape on clay was usually coming around Rome time," Djokovic said.

"So it couldn't be a better time, coming into Roland Garros with a title at this wonderful tournament. I'm going to Paris with a lot of confidence."

Novak Djokovic claimed his 1,000th ATP Tour win with a dominant victory over Casper Ruud in the semi-final of the Internazionali BNL d'Italia on Saturday.

The world number one was in fine touch, winning an imposing 40 per cent of return points on first serve as he defeated the Norweigian world number 10 6-4 6-3 and progressed to the Rome final.

The Serbian becomes the fifth player in the open era to reach 1,000 wins, joining Jimmy Connors, Ivan Lendl, Roger Federer and Rafael Nadal.

After the match, Djokovic asserted how seeing contemporaries in Federer and Nadal achieve respective milestones in 2015 and 2020 provided motivation.

"Thanks to the tournament and the crowd for celebrating the milestone with me," Djokovic said post-match.

"I've seen Roger and Rafa celebrate those milestones in the last couple of years and I was looking forward to get to that 1,000 myself. I'm really, really blessed and privileged to have that many victories on the tour.

"It's been a long time, ever since I won my first match on the tour. Hopefully I can keep going and many more victories to come."

Djokovic will look for victory 1,001 when he faces Stefanos Tsitsipas in the final, after he defeated Alexander Zverev 4-6 6-3 6-3.

The 34-year-old leads their head-to-head matchup 6-2, with the last meeting being Djokovic's epic five-set win in the French Open final last year. Djokovic also won last year's quarter-final in Rome between the two.

This final appearance makes for the Greek world number five's best result in Rome, and he is savouring his time at the Foro Italico.

"It's one of those tournaments that I think has the most history in sport," Tsitsipas said. "As you can see looking around the sides, one of the most beautiful stadiums.

"There's a lot of history playing on these courts and you feel very proud that you made your way here and are able to participate in such a historically rich event."

Stefanos Tsitsipas sank the title hopes of Alexander Zverev as the Greek star edged the Rome edition of their semi-final series on clay this season.

At the Internazionali d'Italia, Tsitsipas scored a 4-6 6-3 6-3 victory over German Zverev to earn a place in Sunday's final.

These two players have now met 12 times in their careers, and Tsitsipas holds an 8-4 head-to-head winning record.

Three of those matches have come at clay-court ATP 1000 tournaments in the past four weeks, with Tsitsipas winning a semi-final on the way to the title in Monte Carlo, then losing to Zverev at the same stage in Madrid.

This latest instalment in Italy was a gripping contest, as the players battled to take on Novak Djokovic or Casper Ruud for the title.

An early break came in the seventh game when, serving at 30-40, Tsitsipas attacked the net but Zverev hit the net cord on his backhand return. The deflection disorientated Tsitsipas slightly and he volleyed wide. One break was enough for the set.

Tsitsipas broke in the second game of the second set, with Zverev serving a double fault at the critical moment, and then got decisively ahead in the fifth game of the decider when Zverev netted on the forehand.

This was a strong win for last year's French Open runner-up, who lost that championship match from two sets up against Djokovic at Roland Garros. It carries Tsitsipas through to his first Internazionali d'Italia final, and a 20th final of his ATP career. He has an 8-11 record in finals to date, and a tour-leading 31 match wins this season.

Felix Auger-Aliassime proved no match for Novak Djokovic, who looks well set to claim his first title of 2022.

It has been a frustrating season to date for the Serbian, who reached a final in Belgrade last month before being beaten by rising star Carlos Alcaraz in Madrid earlier in May.

Yet with Rafael Nadal out of the picture, Djokovic is the clear favourite heading into the Internazionali d'Italia semi-finals, after he beat Auger-Aliassime 7-5 7-6 (7-1) on Friday.

The win not only tees up a semi-final against Casper Ruud, who saw off Nadal's conqueror Denis Shapovalov 7-6 (9-7) 7-5, but also ensures Djokovic will spend a 370th week at the top of the ATP rankings, after he slipped below Daniil Medvedev in the live standings.

Djokovic will add 360 points to his total for reaching the last four, and he now has a milestone 1,000th Tour-level win in his sights when he takes on Ruud for a place in the final. The 34-year-old has won a record 37 Masters 1000 titles so far in his career, including five in Rome.

"I thought it was high-level tennis," Djokovic said. "[Auger-Aliassime] did ask me to raise the level and I had to play consistently well.

"I thought I could have finished the job earlier, but credit to him for fighting back. 

"I know Felix well. He's been around the top of the men's game for quite a few years. He's got a lethal serve, honestly. He's hitting his spots in the box incredibly well with the serve, and it was not easy for me at all to return.

"He's also returning well, he's moving well. He's a very complete player."

The other semi-final will see second seed Alexander Zverev, who beat Cristian Garin 7-5 6-2, take on Stefanos Tsitsipas.

Greek Tsitsipas overcame Jannik Sinner 7-6 (7-5) 6-2, becoming the first player to reach 30 wins on the ATP Tour in 2022.

"We have similar game styles but he is one of the most difficult players to play against on the Tour," Tsitsipas said, previewing his clash with Zverev.

"I have a lot of respect for him. He has achieved a lot so far and I try and look up to him with the things he has achieved."

Rafael Nadal suffered his earliest Internazionali d'Italia exit since 2008 at the hands of Denis Shapovalov on Thursday, but Novak Djokovic advanced to the quarter-finals. 

'King of Clay' Nadal fell to a 1-6 7-5 6-2 defeat to Shapovalov in the third round in Rome, with the Canadian surging to victory after winning 12 straight points from 2-2 in the deciding set. 

The legendary Spaniard stormed through the first set thanks to a series of brilliant returns, but his opponent dominated at the net in the second to take the match the distance. 

Shapovalov then flipped the narrative on its head by winning 14 of a possible 22 return points to set up a quarter-final meeting with Casper Ruud, who beat Jenson Brooksby 6-3 6-4. 

Djokovic is one win away from retaining his status as world number one after taking just 75 minutes to see off three-time grand slam winner Stan Wawrinka 6-2 6-2. 

After a lengthy spell out injured, Wawrinka ended a 15-month wait for an ATP Tour victory at Foro Italico before the Serbian brought his run to an end. 

"It is great to see Stan back and winning. He won two tough matches. You can see he is still not physically where he wants to be. But, nevertheless, he is Stan Wawrinka and he can hurt you if you give him time," Djokovic said. 

"I managed to do well from the beginning. I really moved him around the court and held my serve comfortably except for that loss of my serve in the second set." 

Felix Auger-Aliassime stands between Djokovic and the number one spot after overcoming lucky loser Marcos Giron 6-3 6-2. 

In the other half of the draw, Stefanos Tsitsipas and Jannik Sinner will play out an entertaining quarter-final after they beat Karen Khachano and Filip Krajinovic respectively. 

Alexander Zverev, the defeated finalist in Madrid last week, beat Alex De Minaur 6-3 7-6 (7-5) and will battle Cristian Garin for a place in the final four.

Alexander Zverev avenged his Monte Carlo semi-final loss to Stefanos Tsitsipas, booking his place at the Madrid Open final with a 6-4 3-6 6-2 win on Saturday.

Zverev was dominant on serve, giving up only two break points for the match with a 73 per cent first-serve rate, while winning 40 of a total 48 points on his first serve.

The German will now aim to defend his title in Sunday's final when he faces Carlos Alcaraz, who defeated world number one Novak Djokovic earlier on Saturday.

The second seed will be seeking his sixth ATP 1000 title, with Sunday's final against the home favourite to be his 10th at that level.

"I'm just extremely happy to be in the final here," Zverev said post-match. "I know it's going to be an extremely tough match tomorrow but I hope I can manage to play my best and give myself a chance.

"It's going to be his [Alcaraz] court for the next 15 years probably. It has been Rafa's [Nadal] court for the past 15 years and it's going to be his court for the next 15 years.

"I just hope I can give him some trouble and I hope I can manage to win tomorrow."

Tsitsipas was similarly strong on his first serve but had a much lower rate at only 56 per cent for the match. Zverev simply had more looks at his opponent's second serve, winning 15 points compared to Tsitsipas' eight, but with each holding a 44 per cent success rate.

The defending champion at Caja Magica capitalised when it mattered, though, claiming the opening three games in the deciding set to set up the eventual win.