Fly-half Sam Costelow has been recalled to the Wales starting line-up for Saturday’s Guinness Six Nations clash against Ireland in Dublin.

The Scarlets number 10 went off because of a neck problem suffered when Wales were beaten 27-26 by opening Six Nations opponents Scotland.

He was replaced by Ioan Lloyd, who started at fly-half in the Twickenham appointment with England, but Costelow now returns as a solitary change from that game.

Elsewhere, there are further starts for squad newcomers Cameron Winnett and Alex Mann, while centre George North wins his 120th cap and is only the third Wales player to reach that mark after Alun Wyn Jones and Gethin Jenkins.

Ioan Lloyd feels he has benefited from the presence of former international half-backs Neil Jenkins and Rob Howley in adapting to life as Wales’ number 10.

Lloyd helped orchestrate Wales’ thrilling fightback from 27-0 adrift in their opening Guinness Six Nations game against Scotland, after going on as replacement for an injured Sam Costelow.

His first Wales start then came in the fly-half role at Twickenham last weekend during a 16-14 defeat against England.

The 22-year-old’s impressive versatility has also seen him feature as a full-back, wing and centre during his club and regional career with Bristol and now the Scarlets.

But he admitted that fly-half was his preferred position and he was making the most of having ex-Wales pair Jenkins and Howley, who won almost 150 caps between them, as part of the national squad coaching staff.

“Neil Jenkins has talked a lot about speed into position – and Rob Howley has as well – and also speed from catch to whatever you are going to do, whether it is pass or kick,” Lloyd said.

“We’ve talked a lot through it and obviously I have got to see exactly what he (Jenkins) is talking about over the last couple of weeks. I think that little bit of a reminder has helped me a lot.

“I think the 10 position is one of the game-drivers, one of the main game-leaders, so that sort of pressure is expected.

“It is something that I have anticipated going into the 10 jersey. I think 10s everywhere will take a lot of scrutiny and probably not as much praise as they should in other aspects.

“I am just trying to put my best foot forward and execute my role within the team. There are a lot of learnings from the first two weekends.

“I try not to think about external factors too much, I just try and go out there and play rugby.

“I see myself as a fly-half. Obviously, any opportunity to pull on the red jersey – whether it’s at prop or fly-half – I will take it.”

With Costelow now fit again following a neck problem, it remains to be seen which direction Wales head coach Warren Gatland goes in for fly-half duty against runaway Six Nations title favourites Ireland on Saturday week.

And while Wales have lost their opening two Six Nations games – albeit by a combined margin of just three points – there were also plenty of positive signs from a new-look squad.

Lloyd added: “We talk a lot about playing heads-up rugby, the pictures in front of us and not being afraid to take the opportunities when they come.

“Obviously, there is a fine balance between that and taking risks.

“I think the stuff we tried at the weekend (at Twickenham) weren’t risks. We felt they were on and that is where the space was.

“Execution comes into that then and ours wasn’t good enough at times. I think that is something we can build on.

“There is a confidence around the place. We are a young team, but that doesn’t mean these games are throwaway games. We are still going into them expecting to win and a certain standard from each other.

“The experience isn’t necessarily there from all of us, but we have still got that confidence in training and games that we can execute. When we don’t, it is very disappointing.”

Warren Gatland has made seven changes for Wales’ Six Nations appointment with England after a first-half display against Scotland he admitted was “nowhere near the standards we expect”.

Wales head coach Gatland named the team 24 hours earlier than originally planned, with his line-up including a new front-row and centre George North’s return from injury.

It will be North’s 50th Six Nations appearance, while fly-half Sam Costelow, who went off injured during the first half of Wales’ 27-26 loss to Scotland last weekend, is replaced by Ioan Lloyd, with Tomos Williams at scrum-half.

Gareth Thomas, Elliot Dee and Keiron Assiratti forge the front-row unit at Twickenham on Saturday, while Cardiff flanker Alex Mann is handed a first Wales start following his try-scoring appearance off the bench against Scotland.

Wales went 27 points down to Scotland before staging a stunning second-half recovery, scoring 26 unanswered points, although it could not mask how poor they were prior to that.

Gatland said: “We have been critical and tough on ourselves this week.

“That first half was nowhere near the standards we expect. We simply cannot start the same way this Saturday.

“We showed in the second half against Scotland what we are capable of. Now it is about building on that performance and playing with some tempo from the off.

“We’ve made a few changes to the starting line-up this weekend, which gives opportunities to the players coming in. We need to be accurate and keep our discipline.

“This is a massive game, not only because of the history and what it means to everyone in Wales, but it is an opportunity to get things on track a bit more.

“England are in a rebuilding phase. We will go there with a lot of confidence we can build on that second half.”

Uncapped Bath prop Archie Griffin has been named on the bench, where is joined by Racing 92 lock Will Rowlands.

Rowlands linked up with the Wales squad earlier this week after his partner recently gave birth, while there are also chances among the replacements for Dragons pair Taine Basham and Cai Evans, who is the son of former Wales captain Ieuan Evans.

North has recovered from a shoulder problem to face England, with Lloyd now starting following an outstanding contribution after taking over from Costelow against Scotland.

Mann’s promotion to the starting line-up was expected following James Botham’s withdrawal from the squad because of a knee injury.

Williams, Dee and Assiratti, meanwhile, all made major contributions after being introduced for the second 40 minutes last Saturday.

Wales have not beaten England at Twickenham in the Six Nations since 2012, when centre Scott Williams’ late try confirmed a Triple Crown triumph.

After defeating England away from home during the 2015 World Cup, Wales have lost to their fierce rivals seven times in succession at English rugby headquarters.

Wales boss Warren Gatland has made seven changes to the starting line-up for Saturday’s Guinness Six Nations clash against England at Twickenham.

Centre George North returns from injury for his 50th Six Nations appearances, lining up alongside Nick Tompkins in midfield.

Fly-half Sam Costelow, who went off injured during the first-half of Wales’ 27-26 loss to Scotland last weekend, is replaced by Ioan Lloyd, with Tomos Williams at scrum-half.

Gatland has also selected a new front-row of Gareth Thomas, Elliot Dee and Keiron Assiratti, with Cardiff flanker Alex Mann handed a first Wales start following his try-scoring appearance off the bench against Scotland.

Wales fly-half Sam Costelow is expected to be sidelined until January after suffering shoulder and hamstring injuries.

Scarlets playmaker Costelow was hurt during Wales’ 49-26 victory over the Barbarians on Saturday and went off at half-time.

He is a clear favourite to succeed Dan Biggar, who retired from Test rugby after the World Cup, in Wales’ number 10 shirt.

Wales kick off their Six Nations campaign against Scotland in Cardiff on February 3.

“We are not expecting him in the short term,” Scarlets head coach Dwayne Peel told reporters ahead of Saturday’s United Rugby Championship clash against South African side the Lions.

“It will be beyond Christmas, beyond the new year before we see him. I haven’t an exact date. We are still waiting on the final prognosis and some specialist opinion, really, on that.

“It is a disappointing one for us because he is going to be out for the large part of the first half of the season.

“There is loads more to come from him, and this is obviously a setback in his career at the minute to have this injury.”

Costelow impressed for Wales at the World Cup in France, starting the pool game against Georgia when Gareth Anscombe was a late withdrawal.

And he is the latest member of that squad to be sidelined, with Exeter forward Christ Tshiunza suffering a broken foot on his return to domestic action and number eight Taulupe Faletau continuing his recovery from a broken arm sustained in the Georgia match.

Wales, meanwhile, are without the Six Nations services of Anscombe and full-back Liam Williams, who will play domestic rugby in Japan next year.

Wales say that fly-half talisman Dan Biggar is fit for the Rugby World Cup quarter-final clash against Argentina on Saturday.

Biggar went off after just 12 minutes of Wales’ record 40-6 win against Australia during an unbeaten march through Pool C.

He suffered a pectoral muscle strain and was an unused replacement for the Georgia game last weekend, having been rushed on to the bench when Sam Costelow was summoned to start instead of an injured Gareth Anscombe.

When asked if Biggar was fit to face the Pumas in Marseille, Wales assistant coach Jonathan Thomas said: “Yes.”

There is also encouraging news about Anscombe and full-back Liam Williams.

Anscombe withdrew 45 minutes before kick-off against Georgia due to a groin problem, while Williams was on crutches after taking a blow to his knee.

Those issues came on top of number eight Taulupe Faletau breaking his arm and being ruled out of the tournament remainder.

“At this stage, it is looking positive,” Thomas said, of Anscombe and Williams. “Every day it will evolve. It is probably not as bad as first feared.

“The crutches thing was to try and offload any pressure. It doesn’t mean he (Williams) has done anything severe. He was jogging about today with the medics.

“I saw him (Anscombe) jogging around on the pitch, along with Liam today.

“The first 48 hours after you have a knock is very important in terms of assessing it. With both Liam and Gareth, it is pretty positive.

“That is not me committing to saying they are definitely going to be available. It is an ongoing thing. They were both running around today with the medics, and they will try to progress that each day.”

Wales head coach Warren Gatland is due to name his starting line-up on Thursday, with Aaron Wainwright expected to move from blindside flanker as Faletau’s replacement.

That could then mean captain Jac Morgan wearing the number six shirt and Tommy Reffell starting at openside, although Dan Lydiate and Christ Tshiunza could also be back-row options.

Thomas added: “There was definitely a little bit of a cloud over the victory (against Georgia) because of what happened to Taulupe.

“We have been together for a long time as a whole group, and you build relationships and you become a little bit like a family. When one of your brothers has to leave, it is tough.

“It is what it is. You have got to deal with it and you have got to move on. That is sport and the harsh reality of it.”

Wales face Argentina for the first time in a World Cup game since 1999, and they will start as favourites after collecting 19 points from a possible 20 in their group.

Argentina, in contrast, lost to 14-man England and were unconvincing against Samoa, before clinching qualification by beating Japan.

“For us as a collective, our goal from day one has been to get to knockout rugby,” Thomas said.

“We have achieved that, but we are not satisfied with just getting to the quarter-finals.

“When you get to this stage, any team on their day can beat anyone. There are quality teams and quality players in the last eight.

“I thought they (Argentina) looked more cohesive in their last game against Japan in terms of their attack.

“If you win your first game in the Six Nations, momentum is huge, and it is the same with the World Cup. Every team at this stage will feel confident and feel they have momentum on their side.”