Jurgen Klopp has promised his Liverpool players will show a reaction to their shock 3-0 Europa League home defeat to Atalanta when they host Crystal Palace in the Premier League on Sunday.

Liverpool’s hopes of ending Klopp’s reign with a showpiece European final in Dublin are in real jeopardy after Atalanta punished a lacklustre display to inflict the Reds’ first home defeat in 14 months.

The second leg of the quarter-final tie will be played in Bergamo next week, but before then Liverpool’s attention returns to the intense three-way fight at the top of the Premier League, and a match against Oliver Glasner’s Palace side.

Asked how he could ensure there would be no hangover from Thursday’s result going into Sunday, Klopp said: “First and foremost, I cannot ensure that, never could. But still, it’s the job I have to do.

“I don’t think it was a general low point but performance-wise it was a low point. But the really good thing about a really bad performance is you can play better. Start from there.

“This must feel bad and it does, so let the boys take it home, sleep on it and then come together and recover and go from there.

“On Saturday we will start preparing for Crystal Palace. We have to show a reaction, definitely, 100 per cent clear, but I cannot plan the reaction (straight) after the game…But we will show a reaction, I can promise.”

Klopp made six changes for Thursday’s game, with Joe Gomez, Ibrahima Konate, Kostas Tsimikas, Harvey Elliott, Cody Gakpo and Curtis Jones all coming into the side.

It was a first start since February for Jones, who has made two substitute appearances since injury, while Diogo Jota came off the bench for his first appearance of any kind in almost two months.

Long-term absentees Stefan Bajcetic and Trent Alexander-Arnold were among the substitutes, although Klopp said there was “no chance” of Alexander-Arnold ever playing and he had only been named in the squad because UEFA regulations allow him to select up to 23 players.

With no let up in the schedule and Liverpool still fighting on two fronts, Klopp is eager to get his squad back up to full fitness.

“There is no pressure (to manage the injured players’ returns), that’s just the situation,” he said.

“My job isn’t the easiest job in the world but it’s not the most difficult. But it’s about the players, you need to make sure you get them on the pitch and then it works out somehow.

“We’ve played different line-ups and played really good football and (on Thursday) we didn’t and that’s the reason we lost. That can be the headline. It didn’t work out and that’s absolutely fine and right.

“But we need them all and we need them all aggressive, fit, going for it, a bit angry and full of desire and not so much dealing with your own situation, ‘I need rhythm, I didn’t play for ages’ – try to avoid that.”

Liverpool manager Jurgen Klopp has played down fears of a left-back crisis after Kostas Tsimikas joined Andy Robertson on the injured list.

The Greece international broke his collarbone in the 1-1 draw at home to Arsenal after a challenge from Bukayo Saka saw him collide with his manager in the technical area before falling heavily.

With Robertson, who has been out since October with a dislocated shoulder which required surgery, still a few weeks away from returning, it leaves utility man Joe Gomez, the central defender who has been filling in at right-back to give Trent Alexander-Arnold a break, as the only realistic option.

Even left winger Luis Diaz, who has occupied the role this season as more of an attacking option when Liverpool were chasing the game, is an injury doubt after sustaining a knee problem against the Gunners.

The 18-year-old Luke Chambers has made Europa League and Carabao Cup appearances this season, but is unlikely to be given the responsibility at Burnley on Boxing Day, at home to Newcastle or in the FA Cup away to Arsenal, but may have to provide some support.

“Can Joe play all the games now until I don’t know when? I don’t know, we’ll have to see,” said Klopp.

“Robbo will be back (next month) and Kostas will be definitely out for a long while. I didn’t have time to think it through yet, but it is really tough for us now.

“You have injuries sometimes and you have to accept all of them, but a broken collarbone is really bad because it takes so long to heal.

“Robbo had a different injury, but it takes a long time to recover as well. We all know we need luck in these moments and now we have to just make sure we put Joey in cotton wool and make sure he is ready for the game.”

The injuries to Tsimikas and Diaz adds to an already lengthy list which includes Robertson, Joel Matip (ACL), Thiago Alcantara (hip), Diogo Jota (hamstring), Alexis Mac Allister (knee) and Stefan Bajcetic (calf).

Even with the January Premier League break, Liverpool still have at least seven matches – eight if they progress in the FA Cup – in the next month with a two-legged Carabao Cup semi-final against Fulham adding to the congestion at an already busy period.

But Klopp has increasingly fewer options to rotate and with Burnley buoyed by their win at Fulham, he knows he cannot afford to take their trip to Turf Moor lightly.

“I don’t need the Burnley result to understand their quality,” he added.

“Burnley could have easily had much more points because they had so many good spells in the games where they never saw the situation off, because of young players and some decisions.

“If they could finish these situations off they would definitely win more games. I respect Vinny (Vincent Kompany) a lot because he keeps pushing his idea through.

“I’m impressed with what they are doing and we know if you win once and are coming back to your home stadium you want to win again, and that is what we expect from them.”

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