The San Diego Padres were one strike away from padding their lead atop the NL wild-card standings.

The Detroit Tigers' Parker Meadows changed that with one swing of the bat.

Down 3-0 with two outs and two strikes in the top of the ninth inning, Meadows hit a grand slam to stun the Padres and send the Tigers to a thrilling 4-3 win on Thursday.

Parker hit a 101 mph four-seam fastball off Robert Suarez that travelled 361 feet and landed just over the short left-field fence in San Diego.

San Diego (80-62) lost for the first time in four games and its lead over the Arizona Diamondbacks shrunk to just one-half game for the NL's top wild-card spot.

Jurickson Profar and Xander Bogaerts each homered for the Padres, who end the regular season with a three-game series at Arizona.

Meadows' homer was just his sixth of the season and lifted the Tigers (71-70) back over .500 and within five games of the Royals for the AL's final wild-card spot.

Braves lose, now tied for final NL wild card spot

The Atlanta Braves suffered a 3-1 loss to the last-place Colorado Rockies to drop into a tie for the league's final wild-card berth with the idle New York Mets.

Atlanta and New York have identical 76-64 records with 22 games remaining.

The Braves, who got their lone run on Ramón Laureano's RBI single in the first inning, managed just five hits with Orlando Arcia's second inning-double the only one going for extra bases in the finale with the Rockies (52-89).

Colorado's Michael Toglia and Ezequiel Tovar each hit solo homers off Atlanta starting pitcher Reynaldo Lopez, who gave up three other hits while striking out 11 without a walk in his six innings of work.

Rockies starter Austin Gomber went eight innings, yielding a run and five hits without issuing a walk while striking out six.

Phillies push winning streak to five

The Philadelphia Phillies beat the Miami Marlins 5-2 to extend their winning streak to five games and increase their lead atop the NL East to eight games.

Bryson Stott hit an RBI single in the first inning and a long solo homer during Philadelphia's four-run sixth inning.

Kody Clemens knocked in a pair of runs with a double in the sixth and later came around to score on a wild pitch.

Ranger Suarez gave up three hits over five scoreless innings for the Phillies (84-56), who have won 10 of 12.

The Marlins (52-88) scored their first run in the seventh on an RBI single by Jesús Sánchez and plated their final run an inning later on a throwing error by Clemens.

Ranger Suarez and the Philadelphia Phillies each extended impressive streaks in the team's 7-0 victory over the Cincinnati Reds in Monday's opener of a four-game series.

Suarez increased his run of consecutive scoreless innings to 22 by limiting the Reds to two hits and a walk over seven dominant frames in Philadelphia's seventh straight win. The left-hander struck out five and improved to 4-0 in five starts this season.

Kody Clemens supplied the offence for the Phillies by going 2 for 4 with a three-run homer after being called up from the minors to replace slugger Bryce Harper, who is away from the team to attend the birth of his child.

Hunter Greene threw a season-high seven innings for Cincinnati but was handed the loss after allowing four runs on seven hits.

The Phillies opened the scoring in the second when Alec Bohm and Nick Castellanos reached on back-to-back singles before Bryson Stott plated Bohm with a sacrifice fly.

Johan Rojas tripled off Greene to start the third and came home on Kyle Schwarber's sac fly for a 2-0 edge, and the Phillies tacked on another run in the fourth when Bohm doubled and scored on Stott's fielder's choice grounder.

J.T. Realmuto's run-scoring double in the fifth put Philadelphia up 4-0, and Clemens' blast with Castellanos and Stott aboard in the ninth closed out the scoring.

Gelof's homer in ninth lifts Athletics over Yankees

Zack Gelof broke a scoreless tie with a two-run homer in the top of the ninth inning that gave the Oakland Athletics a 2-0 win over the New York Yankees in the opener of a four-game series.

Abraham Toro greeted reliever Victor Gonzalez with an infield single to start the ninth before Gelof lined a pitch from the Yankees' left-hander into the right field seats to end the scoreless stalemate.

Mason Miller then struck out Anthony Volpe, Juan Soto and Aaron Judge in order in the bottom of the ninth to record his fifth save and put an end to Oakland's three-game losing streak.

The Yankees were dealt a second loss in three games despite a dominant start from Carlos Rodon, who yielded only a fifth-inning single and two walks over seven innings.

A's starter JP Sears was equally good, however, as the former Yankee permitted just three hits and a walk while striking out seven in six innings.

The Yankees played nearly the entire game without manager Aaron Boone, who was ejected by home plate umpire Hunter Wendelstedt in the top of the first inning after questioning whether Oakland lead-off hitter Esteury Ruiz swung a pitch that hit the outfielder.

Boone said after the game Wendelstedt was angered by a remark directed at the umpire by a fan sitting behind New York's dugout. 

Orioles stay hot by extending Angels' struggles

James McCann and Colton Cowser homered to back 5 2/3 scoreless innings from Albert Suarez as the Baltimore Orioles continued their surge with a 4-2 victory over the slumping Los Angeles Angels.

Adley Rutschman added two hits and two RBIs to help Baltimore to its seventh win in eight games, a run that has moved the Orioles a half-game ahead of the New York Yankees for first place in the American League East.

The Angels, meanwhile, have now lost five straight after dropping the opener of this three-game series.

Suarez scattered four hits and two walks while striking out five before departing with a 3-0 lead. McCann's solo homer in the second inning put Baltimore on the board before Jorge Mateo stole two bases in the third to precede Rutschman's run-scoring single.

Rutschman made it 3-0 when he followed Gunnar Henderson's single with a double off Los Angeles starter Reid Detmers in the fifth, and Cowser increased the margin in the seventh with his sixth home run of the season.

All four Baltimore runs came off Detmers, who lasted seven innings and was dealt his first loss of the season after going 3-0 over his first four starts.

The Angels did close the gap in the bottom of the seventh, as Jo Adell homered and Logan O'Hoppe followed with a single before later scoring on Nolan Schanuel's base hit that cut the lead to 4-2.

Los Angeles threatened in the ninth by loading the bases with one out, but Baltimore closer Craig Kimbrel got Schanuel to pop out before fanning Mike Trout to end the game and record his sixth save.

O'Hoppe recorded three of the Angels' eight hits for the game.