France boss Fabien Galthie said his team "lost control" against England as Maro Itoje's late try allowed the hosts to snatch a 23-20 victory at Twickenham.

In a sizzling Six Nations match, France went ahead through Antoine Dupont after just 65 seconds and led 20-13 early in the second half.

They were looking like earning a first victory in the championship in London since 2005 until England came back strongly in the closing stages.

Itoje crossed in the 76th minute, with a TMO verdict showing he had just managed to ground the ball.

Galthie told broadcaster France 2: "In the second period, we lost control of the match. We backed off. We held the line until Maro Itoje scored.

"The English ended up stronger, they managed to occupy the field more than we did. The team had a big game. 

"We were ahead until three minutes from the end, but that's not enough."

France had won their opening two matches before a COVID-19 outbreak in the squad caused the clash with Scotland to be postponed.

Talk of a Grand Slam would have abounded had they held on against England, but it was not to be.

Galthie added in a news conference: "The two teams delivered a great match, before a denouement that must be digested.

"It played out once again in the final minutes. But above all, I am proud of my players, of their solidarity.

"It's a game that makes you grow. We didn't win but they felt we could win it. There are two, three key moments that perhaps would have allowed us to finish it more comfortably.

"In the end, the English dispossessed us of the ball because we conceded penalties, lost balls. But that's good. The team learns."

France face Grand Slam-chasing Wales next Saturday in Paris, knowing a victory over the Red Dragons would keep hopes alive of winning the championship.

Galthie added, according to Le Figaro, that France would react "by keeping the positives".

"We will digest this result together and switch to Wales now," he said. "That match starts right away. It depends on our ability to share and experience together the frustration to plan for the match that awaits us next Saturday."

Antoine Dupont has become the latest member of France's Six Nations set-up to test positive for COVID-19.

Head coach Fabien Galthie, assistant William Servat and another unspecified member of the backroom team have returned positive results since last weekend's 15-13 victory over Ireland in Dublin.

The French Rugby Federation (FFR) announced on Wednesday that no players had tested positive for coronavirus and they had been permitted to return home ahead of further testing on Friday.

Although 11 players returned negative results in the latest batch of testing, Dupont was found to be positive.

"The player who tested positive for COVID-19 is Antoine Dupont," read an FFR statement. "To date, he is asymptomatic. In accordance with protocol he will remain in isolation for the next few days."

The France squad are due to return to the National Rugby Centre in Marcoussis on Sunday to begin preparing for Scotland's visit to Paris the following weekend.

A third member of the France backroom team has tested positive for coronavirus, but the players have been cleared to continue their isolation at home after returning negative results.

The French Rugby Federation confirmed on Tuesday that head coach Fabien Galthie and an unnamed member of staff were positive for COVID-19 and would self-isolate for seven days.

Following another round of testing later that day, assistant coach William Servat returned a positive result.

However, with all players testing negative for the second time in succession, they were permitted to return home on Wednesday.

Further coronavirus tests will be carried out at their homes on Friday and on Sunday, when the players return to the National Rugby Centre in Marcoussis.

France, who won their opening two Six Nations games against Italy and Ireland, are scheduled to face Scotland in Paris on February 28.

The squad for that game is due to be announced on Wednesday.

France had their Six Nations plans disrupted by a positive COVID-19 test that sent the squad into self-isolation on Tuesday.

The French Rugby Federation (FFR) also said head coach Fabien Galthie would be retested amid concerns he may have coronavirus.

It was another figure from within the France camp, who was not named, that returned a positive result following testing on Monday.

Announcing that news, the FFR said on Tuesday: "Following the PCR tests carried out last night in Marcoussis with the France XV, all the players tested negative, a member of the technical staff tested positive, as well as a suspicious and unproven case concerning Fabien Galthie who will be tested again this morning.

"In accordance with health protocol, all members of the team and management were isolated this morning. Interactions are kept to a minimum.

"An additional test at the National Rugby Centre will be carried out on Wednesday morning for the entire squad."

The squad are due to disperse later this week to be allowed a short time at home between matches, with France, who have won their opening two games, not in action again until they face Scotland on February 28 in Paris.

They scored a fine 15-13 win over Ireland in Dublin on Sunday to follow up the opening 50-10 victory over Italy.

The FFR statement added: "Tests will be carried out at home on Friday, as well as on Sunday evening at the National Rugby Centre when the squad reunites.

"The announcement of the 31 players for the Scotland match will take place this Wednesday evening, February 17."

Fabien Galthie has promised France are prepared for whatever "chaos" they might encounter as they prepare to tackle Ireland in Dublin.

The thumping 50-10 win over Italy in Rome last week gave France a fast start to their Six Nations campaign, but they were always expected to win comfortably there, and taking on Ireland is a very different prospect.

Galthie has made two changes to his starting XV for Sunday's game, bringing in wing Damien Penaud and flanker Anthony Jelonch for Teddy Thomas and Dylan Cretin.

France are looking for back-to-back wins over Ireland in the Six Nations for the first time since 2010-11, having beaten them in Paris in October, but Les Bleus have lost five of the past seven encounters between the teams in the championship.

However, Galthie feels France are shaping up as an increasingly formidable force, saying: "You just have to look at the results. We won eight out of 10 matches."

The defeats in that sequence cited by Galthie came with 14 men at Murrayfield in last year's Six Nations, and in sudden death to England in the Autumn Nations Cup.

"In Scotland we lost following a red card and in London we lost in extra time. We are doing it the right way, we continue our march," Galthie said. "We will continue to make progress in many areas. We have a significant space for improvement.

"You have to be prepared for any challenge, anywhere and against anyone. You have to prepare to experience chaos with as much solidity as possible.

"This is what we prepare for without forgetting to face the unexpected."

Galthie believes Penaud may be an ideal physical fit for the task of stopping Ireland, and he said of Jelonch: "He has this ability to be tough in combat, moreover the more the intensity rises, the more he becomes dominant."

France: Brice Dulin, Damien Penaud, Arthur Vincent, Gael Fickou, Gabin Villiere, Matthieu Jalibert, Antoine Dupont; Cyril Baille, Julien Marchand, Mohamed Haouas, Bernard Le Roux, Paul Willemse, Anthony Jelonch, Charles Ollivon, Gregory Alldritt.

Replacements: Pierre Bourgarit, Hassane Kolingar, Uini Atonio, Romain Taofifenua, Dylan Cretin, Baptiste Serin, Anthony Bouthier, Teddy Thomas.