Mauricio Pochettino admitted Moises Caicedo’s international commitments with Ecuador have complicated the midfielder’s early Chelsea career.

The club paid a British record £115million to sign the 22-year-old from Brighton in August but frequent trips to South America to play for his country have limited the time he has been able to spend working with coaching staff at Cobham.

He has played 14 times in all competitions since his arrival, recovering from a red card on his first appearance against West Ham to become a steady if not yet spectacular performer in the heart of midfield.

Since joining Chelsea he has been called up three times by Ecuador and played in six matches, with each international window requiring a more than 11,000-mile round trip, sometimes not arriving back in London until the early hours of the day before Chelsea’s next game.

He revealed in an interview with the club’s website this week that he spent much of his first 10 days in England alone in a hotel room in tears and suffering from homesickness, after joining the Seagulls from Independiente del Valle in his home country in January 2021 during the Covid pandemic.

Restrictions on movement for people arriving into the UK meant he was unable to meet his Brighton team-mates until completing a period of quarantine, during which he phoned his parents in Ecuador asking to return home.

He recovered to become one of the standout successes of the team that Roberto De Zerbi led to a club-best sixth-placed Premier League finish last campaign, sparking a bidding war between Liverpool and Chelsea in which Pochettino’s side were victorious.

The manager reiterated a call for patience as Caicedo navigates life at Chelsea amid a hectic World Cup qualifying schedule internationally.

“When we signed him we knew what is going to happen,” said Pochettino. “He’s an emotional guy, an emotional player that needs time to recover.

“It didn’t help also the international games, travelling to Ecuador, to South America. That is really tough every single month, two or three weeks then go 10, 12 days away, then come back sometimes with some injury.

“It’s not an excuse but it’s the reality. Now we need time. Of course I say (the team) always need to perform. That is our mentality. But in some situations like his, we need to give time and not to be unfair in the way that we assess him.”

Caicedo has formed a reliable partnership in midfield with Enzo Fernandez, who the club paid a then-British record £107m to sign from Benfica in January while Graham Potter was in charge.

Pochettino revealed that the Argentinian World Cup winner asked for extra time off during the summer due to fatigue and was granted permission to join up late with the squad on their United States tour.

“It’s different because Enzo arrived last January, he was with different coaches here,” said the manager. “He asked when we arrived for a period of holiday because he was tired after the World Cup and everything. He joined us in North Carolina.

“I cannot judge the past. Only I can talk from when we arrived (at Chelsea). We expect all, not only (these two), all the players, even the ones not too much involved, to push their level.”

Pierre-Emile Hojbjerg said Tottenham went down with “the flag held high” in their 4-1 loss to Chelsea and has backed the squad to cope with the absence of key personnel.

Spurs lost their unbeaten start to the Premier League season in a pulsating London derby in which five goals were disallowed and the hosts played the final 35 minutes with nine men.

To add salt into fresh Tottenham wounds, Micky van de Ven was forced off with a hamstring injury and James Maddison had to be withdrawn due to an ankle knock, while Cristian Romero and Destiny Udogie, who were both sent off, will sit out this weekend’s trip to Wolves.

Ange Postecoglou’s side battled admirably, first with 10 men from the 35th minute and then when down to nine early in the second half, but Nicolas Jackson grabbed the first of his three goals with quarter of an hour left to finally break the hosts’ resolve.

Hojbjerg said: “I think we went down with the flag held high. We gave it our all but the result hurts a lot.

“We showed what we had in our hearts but the result hurts.

“Tuesday we have a day off and when we see each other on Wednesday, we’ll gather the pieces and focus on the next game, as we have to.

“Everyone has to show their availability and show they are prepared to do what it takes.

“A good squad is not 11 players. It is 18 or 25 players and this is what we have to show. The result hurts a lot but we have to keep going.”

Mauricio Pochettino’s first return to Tottenham had initially started in the worst possible fashion when Dejan Kulusevski’s curled effort deflected off Levi Colwill and beyond the helpless Robert Sanchez after six minutes.

The wheels started to fall off during a 57-minute first half where four goals were chalked off by video assistant referee John Brooks at Stockley Park, who decided that Romero’s tackle on Enzo Fernandez was worthy of a red card and a penalty in the 33rd minute.

Spurs’ uphill task increased further when Udogie was shown a second yellow after 10 minutes of the second period, but Postecoglou deployed a high line and Guglielmo Vicario starred in the sweeper-keeper role before Jackson made it 2-1.

Tottenham remained resolute and started to create chances with substitute Eric Dier marginally offside when he volleyed home soon after Jackson’s first goal before Rodrigo Bentancur and Son Heung-min squandered opportunities.

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Jackson made the points safe in stoppage time when he lashed in from Conor Gallagher’s pass, but Spurs supporters greeted the goal with a standing ovation for their crestfallen players.

Kulusevski said: “It was unbelievable, honestly. Some things are bigger than life, bigger than football, bigger than the wins.

“Honestly I was really proud of that moment and the fans. I was grateful and it makes me want to give more back.

“It has to give us fuel. We lost the game, we hate to lose, it was the first of the season, but we have to make sure this doesn’t happen again and play 11 v 11 because then it is much harder to beat us.”

The consequences of this defeat could be long-lasting with Romero set for a three-match ban, which will rule him out of matches with Wolves, Aston Villa and Manchester City.

Of bigger concern is centre-back partner Van de Ven after he pulled up at the end of the first half in a sprint with Jackson, which saw him helped off the pitch and he was later seen on crutches.

Udogie will also miss Saturday’s clash at Wolves and with Ben Davies nursing an ankle knock, Postecoglou could use Under-21 defenders Ash Phillips or Alfie Dorrington this weekend.

“It will be a test for sure. They (Van de Ven and Maddison) are amazing players and I hope they are back very, very soon, but as you saw the players that came in were amazing,” Kulusevski said.

“We train really hard every day and everybody is ready. You saw Eric Dier, he came in, did his first appearance and was unbelievable. The guys are ready.

“Everybody wants to play and it is so high level the training. So, if (Phillips) will be called, he will be ready.”

Ange Postecoglou lamented that VAR has diminished the authority of referees after he watched nine-man Tottenham lose for the first time in the Premier League against Chelsea.

It was a frenetic meeting between the two rivals that saw five disallowed goals, two red cards, a penalty and two Spurs players forced off during the first half with injury, as Mauricio Pochettino marked his return to north London with a memorable 4-1 victory.

But the match was dominated by VAR’s involvement with the red cards two of nine decisions referred to the video referee.

Even with nine men the hosts continued to take the game to Chelsea and were well in the contest before Nicolas Jackson twice sprung their high line in stoppage time to add his team’s third and fourth goals and complete an unlikely hat-trick.

Postecoglou’s team had been comfortably on top in the first half before Cristian Romero’s red card in the 33rd minute, dismissed for a dangerous challenge on Enzo Fernandez and conceding the penalty from which Cole Palmer equalised Dejan Kulusevski’s deflected goal.

Destiny Udogie was also dismissed on 55 minutes, receiving a second yellow card for a foul on Raheem Sterling, but it took a further 20 minutes before Chelsea finally took the lead for the first time through Jackson.

Spurs’ night was compounded by the loss of James Maddison and Micky van de Ven to injury on top of what is likely to be a three-game ban for Romero.

But it was VAR’s impact that dominated Postecoglou’s thoughts after the game after a total of 21 minutes were added on at the end of each half.

“It’s hard to analyse from a football perspective,” he said.

“We’re left with a result which is disappointing, but super proud of the players’ efforts and will and desire to get something from the game.

“(Lengthy VAR pauses) are going to become the norm, I think it’s where the game is heading. Unfortunately it’s how we’re going to have to watch and participate in football from now on.

“I don’t like it. I don’t like the standing around, the whole theatre around waiting for decisions. But I know I’m in the wilderness on that.

“In my 26 years, I was always prepared to accept the referee’s decision, good, bad or otherwise, and I’ve had some shockers in my career. I’ve had some go my way as well.

“I’ll cop that because I just want the game to be played. But when we’re complaining about defections every week, this is what’s going to happen.

“People are going to forensically scrutinise everything to make sure they’re comfortable it’s right, and even at the end of that, we’re still not happy.

“It’s just diminishing the authority of the referee. You can’t tell me referees are in control of games. They’re not. Control is outside of that, but that’s where the game’s going. You have to accept it and try and deal with it.”

Pochettino reflected on a game in which, despite a host of contentious decisions, he felt his team were deserved victors.

“I think we deserved to win,” he said.

“We forced them to make too many mistakes. Tottenham were better in the first 15 minutes but then we matched the game. Our performance was good.

“Everything you can see during the game I think was fair. We compare to the Tottenham Liverpool game, a similar game like today. Liverpool complained. But today, everything that happened was fair. That’s why I think 4-1, the performance was good.”

Chelsea fell to a third home defeat of the season as Brentford maintained their 100% winning record at Stamford Bridge in the Premier League with a deserved 2-0 victory.

Ethan Pinnock took advantage of non-existent marking to head the visitors in front shortly before the half-hour mark after Mauricio Pochettino’s side had failed to take advantage of a first half in which they dominated.

Thereafter there was little genuine attacking threat nor hope of salvation, as the hosts took a worrying backwards step towards the goal-shy, hesitant play that characterised the manager’s early games.

Robert Sanchez was embarrassed in added time after joining his team’s attack for a corner, failing to catch Neal Maupay in a foot race as he broke with the ball, allowing Bryan Mbeumo to score in an empty net to compound home fans’ woes.

Chelsea’s dire form at Stamford Bridge now stands at one win in their last 13 games in the league, with August’s victory over Luton their only success here in seven months.

They were without Enzo Fernandez and Mykhailo Mudryk, key components in their recent uptick in form, with neither player risked after picking up knocks in training on Friday.

In place of Mudryk came Noni Madueke, in for his first start under Pochettino, and he wasted little time in staking a case to his manager, standing up Vitaly Janelt on the right of the penalty area and opening his body to unleash a wicked, bending effort that thumped the crossbar.

It was a busy start from Chelsea. Conor Gallagher, captain again with Reece James fit only for the bench, stung the palms of Mark Flekken when he shot low at goal from 30 yards.

Marc Cucurella found space from a wonderful ball into the box from Cole Palmer, but the defender could summon neither power not placement with his right foot.

Raheem Sterling looked in electric mood. His dazzling burst through the middle saw the ball break to Madueke, who shepherded it inside for Palmer to return for Sterling who had continued his run. The move deserved a goal; instead the England forward ballooned his shot into the Matthew Harding Stand.

As the half wore on Chelsea became increasingly camped in the visitors’ half, shifting focus from probing for the critical pass in central positions in favour of balls down the channels, where Madueke and Sterling would not allow Brentford peace.

But there was a feeling of old habits creeping into Chelsea’s play, with the creative fluency of recent weeks not so forthcoming. The period ended with Pochettino remonstrating with a fan who questioned Nicolas Jackson’s lack of involvement, the manager of a mind that only supportive voices were welcome, but doubtless aware privately of his team’s shortcomings.

There was almost a goal within minutes of the restart, Janelt left to rue profligate finishing after he was left free 12 yards out but fired straight at Sanchez. It was a stark warning, but one Chelsea’s defence would not heed.

On 58 minutes, their generous marking struck again and this time Pinnock readily accepted the gift.

It was a smart link-up between Kristoffer Ajer and Mbeumo from a throw-in on the right that began the move, with Mbeumo given space to run the ball to the byline and hoist a cross. The delivery hung high in the air, finally dropping into the six yard box where Axel Disasi did little more than observe as Pinnock powered beyond him and beat Thiago Silva to the ball to thump his header home.

The shock jolted Chelsea from whatever rhythm they had inherited from the first half. Still they hogged the ball, but rarely was Flekken tested as they toiled in vain for an equaliser.

Substitute Yehor Yarmolyuk should have made it 2-0 on the break in the final minutes, he was denied point-blank by Sanchez, before Mbeumo lashed millimetres wide of the post.

Pochettino’s assistant Jesus Perez was sent off with frustrations between the two benches boiling over, and it got even worse for the home side with Mbeumo’s tap-in and the end of Chelsea’s mini-revival.

Chelsea had to rely on reinforcements from the bench to survive a scare as a Mauricio Pochettino’s young selection recovered from a goal down to beat League Two AFC Wimbledon 2-1 in the Carabao Cup second round.

It took a first Chelsea goal from substitute Enzo Fernandez to break the visitors’ stubborn resolve at Stamford Bridge, after they had stunned home fans to take the lead through midfielder James Tilley’s 19th-minute penalty.

Noni Madueke equalised from the spot in first-half added time, as an unfamiliar starting XI made heavy weather of seeing off Johnnie Jackson’s team.

Pochettino brought in three players for their full first-team debuts – Mason Burstow, Ian Maatsen and Diego Moreira – but it took the introduction of a more recognised trio in the second half for them to see off the Dons, who were a stubborn defensive match for their Premier League opponents.

Nicolas Jackson, fresh from his first goal for the club against Luton, was introduced and provided a spark that had been absent, with Malo Gusto and Fernandez helping lend Chelsea the required bite.

The World Cup-winner struck the winner 18 minutes from the end after an unfortunate error from goalkeeper Alex Bass, as Wimbledon went down fighting.

The visitors had been awarded a penalty in the 16th minute when Robert Sanchez flew from his goal in an attempt to deal with Morgan Williams’ deep free-kick, instead crashing his fist into the face of Harry Pell. From the spot, Tilley thumped his kick down the centre as Sanchez dived to his right.

Chelsea almost hit back within minutes when Marc Cucurella, in the side despite reported negotiations over a move to Manchester United, carried the ball to the byline and pulled it back for Maatsen who turned cleverly and struck a low left-footed effort. Bass was relieved to see the ball skid inches past his near post off defender Joe Lewis.

On the half-hour mark, Cucurella again was the provider from the left, this time whipping in a cross which Burstow headed narrowly wide.

Madueke, making his first start under Pochettino, looked Chelsea’s best hope of a first-half response, his penetrating runs and movement off the ball as great a threat to Wimbledon’s lead as the home side could muster. But with the visitors camped largely in their own half, there was little room in which to manoeuvre.

Then on the stroke of half-time came a way back. Madueke, on another darting run, won a penalty as Alex Pearce went to ground with a clumsy challenge. The 21-year-old stepped up and capped a fine individual first period by clipping it coolly past Bass for 1-1.

It was the hosts’ only shot on target of the opening 45 minutes despite enjoying 85% of possession but the arrival at half-time of Jackson ignited something in attack.

His clever footwork and vision found Conor Gallagher and Chelsea’s captain for the night finally warmed the hands of Bass with a right-footed shot that was well saved in the 54th minute.

Fernandez was summoned from the bench and almost made an instant impact, striking at goal from 30 yards and drawing a superb two-handed save from Bass at full stretch. He would not have to wait much longer for his first Chelsea goal.

In the 72nd minute a long ball up from the back was hit by the onrushing goalkeeper straight into Jackson, the ball deflecting into Fernandez’s path to give the Argentinian the simple task of bending it into an empty goal with Bass stranded.

The goalkeeper went a long way towards making amends with a flurry of fine saves to keep the score down.

It was a brave showing from him and his team and might it might have earned them a penalty shoot-out had substitute Ali Al-Hamadi’s last-gasp effort not deflected wide off Axel Disasi.

However, Chelsea’s strength in reserve ultimately eased the Blues into the third round.