Tottenham have confirmed left-back Destiny Udogie will miss the rest of the season after undergoing surgery on his left thigh.

Udogie has flourished in his first campaign in the Premier League and made 30 appearances in all competitions for Spurs.

The Italian defender has caught the eye with his ventures into midfield under Ange Postecoglou but he revealed on Saturday night his 2023-24 campaign was over.

Spurs said in a statement on their website: “We can confirm that Destiny Udogie has undergone surgery to his left quadriceps, having sustained an injury in training earlier this week.

“The defender will continue his rehabilitation with our medical staff and is expected to rejoin the squad during pre-season.”

News of Udogie’s injury is untimely for a Tottenham team who lost 4-0 at Newcastle last weekend. Spurs lost ground in the battle for Champions League qualification as a result and are currently three points behind fourth-placed Aston Villa.

Tottenham’s top-four prospects have been dealt a blow after full-back Destiny Udogie was ruled out for the rest of the season.

Udogie has flourished in his first campaign in the Premier League and made 30 appearances in all competitions for Spurs.

The Italian defender has caught the eye with his ventures into midfield under Ange Postecoglou, but revealed in a post on Instagram that he had surgery on an unspecified injury and would not play again in the 2023-24 season.

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“An injury brings my season to an early end,” Udogie wrote.

“It doesn’t take away from how grateful I am to every person that has supported me this year.”

News of Udogie’s injury is untimely for a Tottenham team who lost 4-0 at Newcastle last weekend.

Spurs lost ground in the battle for Champions League qualification as a result and are currently three points behind fourth-placed Aston Villa.

Tottenham moved back into the Champions League places after three goals in eight second-half minutes fired them to a chaotic 3-2 win at home to Brentford.

Spurs were sluggish in the first half and trailed to Neal Maupay’s 15th-minute opener but Ange Postecoglou’s half-time team talk seemingly did the trick.

Destiny Udogie and substitute Brennan Johnson scored within 72 seconds of each other at the start of the second period before Richarlison grabbed his seventh goal in his last seven Premier League games.

There was still time for Ivan Toney to score again on his second appearance since his return from a betting ban but Tottenham held on to leapfrog Aston Villa and reclaim fourth spot.

Spurs were eager to bounce back after exiting the FA Cup last Friday and James Maddison was handed a start but Brentford also had their returning hero involved with Toney leading the line again.

While all eyes were on Toney, it was the Bees’ other forward who broke the deadlock.

Udogie gave away possession to Christian Norgaard who sent Toney clear and while goalkeeper uglielmo Vicario thwarted the England international, Maupay was on hand to bundle in to score for a fourth consecutive match.

Maupay and Toney celebrated by mimicking Maddison’s dart throw celebration but it was a deserved opener after Mads Roerslev had a goal ruled out for offside minutes earlier.

Postecoglou’s side initially reacted well to going behind with Timo Werner testing Mark Flekken after a fine Rodrigo Bentancur run before Werner headed wide from a Pedro Porro corner.

Richarlison then flashed an effort past the post from range but Spurs started to get sucked into Brentford’s gameplan that has earned them multiple wins at Chelsea and success at Man City during the past two seasons.

Frustration began to boil over at the away side’s pedestrian pace at set-pieces and the Bees nearly doubled their advantage when Ethan Pinnock backheeled wide after another dangerous ball into Tottenham’s penalty area.

Dejan Kulusevski and Maupay were booked by David Coote for a shoving match soon after before Vicario punched away a Toney header to ensure it was 1-0 at the break.

Postecoglou made a double change at half-time with Pierre-Emile Hojbjerg and Johnson introduced.

Werner and Udogie lacked cutting edge in the first half but combined to equalise three minutes into the second half.

Udogie carried the ball forward, played a quick one-two with Werner and, after his first effort had been blocked by Pinnock, he was on hand to slot home to make it 1-1.

The Brentford players had barely got back into position when Tottenham grabbed another.

Kulusevski sent Werner away and the RB Leipzig loanee showed a clinical edge with a fine ball to the back post where substitute Johnson tapped in.

Johnson celebrated by copying Maddison’s darts celebration and Richarlison followed suit in the 56th minute.

Tottenham were at their free-flowing best now with Udogie finding Maddison, who cut back and had a shot blocked by Pinnock but Richarlison was on hand to steer home.

Brentford remained a threat and after Toney had sent two efforts wide, he made it third time lucky in front of England manager Gareth Southgate with 67 minutes played.

It was another gift from Udogie, who failed to look up and sent his pass back straight to Toney and he rifled into the corner to set up a grandstand finish.

Maddison’s night ended early with what appeared to be cramp before the Bees created one final chance but Vicario tipped over Josh Dasilva’s close-range volley to earn Spurs a precious three points.

Pierre-Emile Hojbjerg said Tottenham went down with “the flag held high” in their 4-1 loss to Chelsea and has backed the squad to cope with the absence of key personnel.

Spurs lost their unbeaten start to the Premier League season in a pulsating London derby in which five goals were disallowed and the hosts played the final 35 minutes with nine men.

To add salt into fresh Tottenham wounds, Micky van de Ven was forced off with a hamstring injury and James Maddison had to be withdrawn due to an ankle knock, while Cristian Romero and Destiny Udogie, who were both sent off, will sit out this weekend’s trip to Wolves.

Ange Postecoglou’s side battled admirably, first with 10 men from the 35th minute and then when down to nine early in the second half, but Nicolas Jackson grabbed the first of his three goals with quarter of an hour left to finally break the hosts’ resolve.

Hojbjerg said: “I think we went down with the flag held high. We gave it our all but the result hurts a lot.

“We showed what we had in our hearts but the result hurts.

“Tuesday we have a day off and when we see each other on Wednesday, we’ll gather the pieces and focus on the next game, as we have to.

“Everyone has to show their availability and show they are prepared to do what it takes.

“A good squad is not 11 players. It is 18 or 25 players and this is what we have to show. The result hurts a lot but we have to keep going.”

Mauricio Pochettino’s first return to Tottenham had initially started in the worst possible fashion when Dejan Kulusevski’s curled effort deflected off Levi Colwill and beyond the helpless Robert Sanchez after six minutes.

The wheels started to fall off during a 57-minute first half where four goals were chalked off by video assistant referee John Brooks at Stockley Park, who decided that Romero’s tackle on Enzo Fernandez was worthy of a red card and a penalty in the 33rd minute.

Spurs’ uphill task increased further when Udogie was shown a second yellow after 10 minutes of the second period, but Postecoglou deployed a high line and Guglielmo Vicario starred in the sweeper-keeper role before Jackson made it 2-1.

Tottenham remained resolute and started to create chances with substitute Eric Dier marginally offside when he volleyed home soon after Jackson’s first goal before Rodrigo Bentancur and Son Heung-min squandered opportunities.

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Jackson made the points safe in stoppage time when he lashed in from Conor Gallagher’s pass, but Spurs supporters greeted the goal with a standing ovation for their crestfallen players.

Kulusevski said: “It was unbelievable, honestly. Some things are bigger than life, bigger than football, bigger than the wins.

“Honestly I was really proud of that moment and the fans. I was grateful and it makes me want to give more back.

“It has to give us fuel. We lost the game, we hate to lose, it was the first of the season, but we have to make sure this doesn’t happen again and play 11 v 11 because then it is much harder to beat us.”

The consequences of this defeat could be long-lasting with Romero set for a three-match ban, which will rule him out of matches with Wolves, Aston Villa and Manchester City.

Of bigger concern is centre-back partner Van de Ven after he pulled up at the end of the first half in a sprint with Jackson, which saw him helped off the pitch and he was later seen on crutches.

Udogie will also miss Saturday’s clash at Wolves and with Ben Davies nursing an ankle knock, Postecoglou could use Under-21 defenders Ash Phillips or Alfie Dorrington this weekend.

“It will be a test for sure. They (Van de Ven and Maddison) are amazing players and I hope they are back very, very soon, but as you saw the players that came in were amazing,” Kulusevski said.

“We train really hard every day and everybody is ready. You saw Eric Dier, he came in, did his first appearance and was unbelievable. The guys are ready.

“Everybody wants to play and it is so high level the training. So, if (Phillips) will be called, he will be ready.”