The San Diego Padres were one strike away from padding their lead atop the NL wild-card standings.

The Detroit Tigers' Parker Meadows changed that with one swing of the bat.

Down 3-0 with two outs and two strikes in the top of the ninth inning, Meadows hit a grand slam to stun the Padres and send the Tigers to a thrilling 4-3 win on Thursday.

Parker hit a 101 mph four-seam fastball off Robert Suarez that travelled 361 feet and landed just over the short left-field fence in San Diego.

San Diego (80-62) lost for the first time in four games and its lead over the Arizona Diamondbacks shrunk to just one-half game for the NL's top wild-card spot.

Jurickson Profar and Xander Bogaerts each homered for the Padres, who end the regular season with a three-game series at Arizona.

Meadows' homer was just his sixth of the season and lifted the Tigers (71-70) back over .500 and within five games of the Royals for the AL's final wild-card spot.

Braves lose, now tied for final NL wild card spot

The Atlanta Braves suffered a 3-1 loss to the last-place Colorado Rockies to drop into a tie for the league's final wild-card berth with the idle New York Mets.

Atlanta and New York have identical 76-64 records with 22 games remaining.

The Braves, who got their lone run on Ramón Laureano's RBI single in the first inning, managed just five hits with Orlando Arcia's second inning-double the only one going for extra bases in the finale with the Rockies (52-89).

Colorado's Michael Toglia and Ezequiel Tovar each hit solo homers off Atlanta starting pitcher Reynaldo Lopez, who gave up three other hits while striking out 11 without a walk in his six innings of work.

Rockies starter Austin Gomber went eight innings, yielding a run and five hits without issuing a walk while striking out six.

Phillies push winning streak to five

The Philadelphia Phillies beat the Miami Marlins 5-2 to extend their winning streak to five games and increase their lead atop the NL East to eight games.

Bryson Stott hit an RBI single in the first inning and a long solo homer during Philadelphia's four-run sixth inning.

Kody Clemens knocked in a pair of runs with a double in the sixth and later came around to score on a wild pitch.

Ranger Suarez gave up three hits over five scoreless innings for the Phillies (84-56), who have won 10 of 12.

The Marlins (52-88) scored their first run in the seventh on an RBI single by Jesús Sánchez and plated their final run an inning later on a throwing error by Clemens.

Zack Short broke a scoreless tie with a run-scoring double in the sixth inning, and Reynaldo Lopez and three Atlanta relievers combined on a five-hitter as the Braves opened a three-game series with the Chicago Cubs with Monday's 2-0 win.

Ronald Acuna Jr. plated Short with a single as the Braves scored both of the game's lone runs against reliever Hayden Wesneski, who replaced Shota Imanaga after the Japanese lefty tossed five scoreless innings to deliver another effective start in his debut MLB season.

Imanaga scattered seven hits and struck out eight to lower his MLB-leading ERA to 0.96. The offseason addition extended his team record with an eighth consecutive start of allowing two earned runs or fewer to begin his major league career.

Lopez was just as good while also not factoring in the decision, as the right-hander yielded just two hits and a pair of walks over five innings. Ray Kerr (2-0) received the win with two scoreless innings in relief of Lopez.

Wesneski (2-2) took over in the sixth and struck out the first two Atlanta batters before giving up a double to Travis d'Arnaud. Short, starting at third base with Austin Riley dealing with left-side tightness, then laced a double into the right field corner to put the Braves ahead.

Acuna followed with a single to left to extend the lead to 2-0.

The Cubs threatened in the ninth by putting their first two runners on, but A.J. Minter worked out of the jam to notch his first save of the season and close out the Braves' fifth win in six games.

Stott the hero as Phillies rally past Mets in 10 innings

Bryson Stott ignited a ninth-inning rally with a solo homer, then drove in the go-ahead run in the 10th as the Philadelphia Phillies rallied for a 5-4 win over the rival New York Mets.

The Phillies trailed 4-2 entering the ninth before scoring twice off Mets closer Edwin Diaz, who forced in the tying run by hitting Alec Bohm with a pitch with the bases loaded.

Stott started the comeback with a lead-off homer and pinch-hitter Kody Clemens followed with a single before Diaz issued a pair of walks to load the bases with two out. The two-time All-Star then hit Bohm in the forearm on an 0-2 count to bring in Clemens and force extra innings.

In the 10th, designated runner Bryce Harper advanced from second to third on a wild pitch from Sean Reid-Foley before crossing the plate on Stott's sacrifice fly.

Jose Alvarado then kept the Mets scoreless in the bottom of the 10th to record his eighth save and give the National League-leading Phillies a victory to start this four-game, home-and-home series.

Stott scored the game's first run after reaching on a single in the top of the second inning and later coming home on Garrett Stubbs' infield hit.

The Mets answered with two runs in the bottom of the inning, as Pete Alonso and J.D. Martinez had back-to-back doubles off Philadelphia starter Cristopher Sanchez to tie the game before Tomas Nido brought in Martinez with a single.

Starling Marte doubled off Sanchez in the third and later scored on a bases-loaded walk to Martinez to increase the Mets' lead to 3-1. It remained that way until the top of the seventh, when the Phillies put two aboard on singles by Edmundo Sosa and Brandon Marsh in front of Johan Rojas' run-producing groundout.

New York restored a two-run advantage in its half of the seventh when Alonso scored on Bohm's error on a grounder hit to third off the bat of Tyrone Taylor.

Martinez finished 3 for 4 with two RBIs in the Mets' sixth loss in nine games. Philadelphia has now won 10 of its last 12.

Ramirez's four RBIs helps Guardians extend Rangers' skid

Jose Ramirez went 2 for 3 and drove in four runs as the Cleveland Guardians extended the Texas Rangers' losing streak to a season-high four games with Monday's 7-0 victory.

Ramirez knocked in two of Cleveland's four runs in the eighth inning that broke a scoreless tie as the American League Central leaders took the opener of this three-game series.

The game featured a pitching duel between Cleveland's Tanner Bibee and Texas' Michael Lorenzen, who held the Guardians to one hit through seven innings before the visitors broke through against the Rangers' bullpen in the eighth.

Jose Leclerc (3-3) relieved Lorenzen and was greeted by a double from Estevan Florial, who scored on Brayan Rocchio's single two batters later for a 1-0 Cleveland lead.

The Guardians then loaded the bases on a walk and a single before Ramirez drove in two with a base hit to extend the margin. Texas reliever Jacob Latz later forced in another run with a wild pitch that allowed Andres Gimenez to score from third.

Cleveland tacked on three more runs in the ninth on Gimenez's RBI double and another two-run single from Ramirez.

Bibee allowed just three hits and two walks before being removed with one out in the sixth.