Manny Machado homered twice and drove in five runs and Jackson Merrill had three hits, including a home run, to lead the streaking San Diego Padres to an 11-1 rout of the Boston Red Sox on Saturday.

Machado hit a two-run homer in the third inning off Tanner Houck and added a three-run shot in the fifth to extend the lead to 8-0.

It was the 40th career multihomer game for Machado, who is 17 for 41 (.415) with four home runs and 12 RBIs in his last 10 games.

Bryce Sullivan also went deep as the Padres (46-41) won their season-high fifth straight and ninth in 10 contests to move five games over .500.

Michael King limited the Red Sox to one run and five hits over six innings with one walk and six strikeouts.

Houck was tagged for a career-worst eight runs in 4 1/3 innings on his 28th birthday, raising his ERA from an AL-best 2.18 entering the day to 2.67.

Jarren Duran homered for Boston, which has been outscored 29-7 during a three-game skid after an 8-1 stretch.

Astros score 8 unanswered to rally past Mets

Alex Bregman delivered a two-run single to cap a three-run eighth and the Houston Astros rallied from five down for a 9-6 victory over the New York Mets.

Jake Meyers hit an early home run and Jeremy Pena triggered the comeback with a two-run double during a three-run fourth against starter Tylor Megill.

The Astros drew four walks and had just one hit in the decisive eighth inning. Reed Garrett threw a run-scoring wild pitch before Bregman’s line single to right scored two to give Houston a 7-6 lead.

Maurico Dubon added some insurance with a two-run double in the ninth and the Astros won for the 11th time in 15 games.

Mark Vientos homered and Jose Iglesias had three hits for the Mets, who had won four straight and 16 of 20.

Kjerstad’s slam lifts Orioles

Rookie Heston Kjerstad hit his first career grand slam and Anthony Santander added his 13th home run this month as the Baltimore Orioles held on for their fourth straight win, 6-5 over the reeling Texas Rangers.

The Orioles became the third team in MLB history to hit at least 60 homers in a calendar month, joining the 2023 Atlanta Braves (61 in June) and the 2019 Yankees (74 in August).

Baltimore has gone deep 14 times in its last five games and leads the majors with 139.

Cade Povich earned his first major league win after allowing two runs – both on homers – and five hits in five innings.

Craig Kimbel walked two in the ninth but got Adolis Garcia to fly out for the final out for his 19th save.

Corey Seager, Derek Hill, Nathaniel Lowe and Garcia homered for the Rangers, who matched a season high with their sixth straight loss and dropped their ninth in a row on the road.

Seager left in the fifth inning after he was hit on his left wrist by a pitch from Povich. The Rangers said X-rays on the wrist were negative, and the four-time All-Star would be evaluated Sunday.