Aleksandar Mitrovic's late winner saw Serbia seal their spot at the 2022 World Cup with a 2-1 win over Portugal in Lisbon.

Portugal went ahead after just two minutes as Bernardo Silva capitalised on a defensive error to set up Renato Sanches, who opened the scoring with an unerring finish. 

Dusan Tadic's deflected strike levelled the scores later in the first half, with Rui Patricio partially culpable for allowing the ball to cross the line.

Substitute Mitrovic completed a dramatic turnaround in the 90th minute as he headed in from Tadic's cross to send Serbia top of Group A and condemn Portugal to the playoffs.

Cristiano Ronaldo was denied a dramatic late winner in contentious circumstances as Portugal threw away a two-goal lead to draw 2-2 with Serbia in World Cup qualifying on Saturday.

Diogo Jota had seen his double cancelled out by Aleksandar Mitrovic and Filip Kostic – the former becoming Serbia's all-time leading scorer with his 39th international goal – at the Rajko Mitic Stadium.

Portugal skipper Ronaldo was then convinced his last-gasp effort had crossed the line but the officials judged Stefan Mitrovic cleared before all of the ball had done so, with the Juventus superstar booked for his protestations before he angrily threw his captain's armband on the floor.

It means both Portugal and Serbia, who had Nikola Milenkovic sent off prior to the late drama, each have four points - one more than Luxembourg, who sealed a remarkable 1-0 win against the Republic of Ireland.