The New York Yankees' playoffs hopes were dealt a blow despite Jordan Montgomery sending down 12 strikeouts as they lost 3-2 to the Baltimore Orioles in 10 innings in MLB on Thursday.
Austin Hays delivered a walk-off single in the 10th inning to give the Orioles the win, with the Yankees moving to an 82-65 record, slipping behind the Boston Red Sox (83-65) in the American League (AL) Wild Card race.
Joey Gallo had put the Yankees ahead with a solo home run in the second inning, his fifth in 11 games. Gio Urshela got Gary Sanchez home in the second for a 2-0 lead.
But the Orioles worked their way back, initially as rookie Ryan Mountcastle made history with a 438-foot solo home run in the sixth inning off Montgomery.
Mountcastle's 29th homer of the season eclipsed Cal Ripken Jr's franchise record which has stood since 1982.
That was the only earned run Montgomery allowed, conceding six hits and one walk, with his 12 Ks.
Kelvin Gutierrez tied the game off a wild Clay Holmes pitch in the ninth inning, before Hays' chopper got Jahmai Jones home for the win.
Rays return to winners' column
The Tampa Bay Rays returned to winning ways with a 5-2 series-opening victory over the Detroit Tigers, with Yandy Diaz setting the tone with a lead-off homer, along with a late two-run shot from Mike Zunino.
Mathematically the Rays, who improved to 91-56 in top spot in the AL East division, could clinch their postseason spot on Monday.
Bryce Harper drove in four runs including a three-run homer for his 33rd of the season as the Philadelphia Phillies crushed the Chicago Cubs 17-8.
The Phillies were buoyed by a seven-run fourth inning, helping them stay in the Wild Card hunt at 74-72.
Fernando Tatis Jr launched a solo line drive home run, his 39th of the season, as the San Diego Padres toppled the San Francisco Giants 7-4.
Carlos Correa crushed a three-run shot while Alex Bregman drove in four runs as the Houston Astros downed the Texas Rangers 12-1.
The Cincinnati Reds stopped their slide and boosted their Wild Card hopes with a 1-0 win over the Pittsburgh Pirates.
White Sox ejected after Ohtani hit
There was late drama as the Los Angeles Angels won 9-3 over the Chicago White Sox with reliever Mike Wright Jr ejected after three wayward pitches, with the latter hitting Shohei Ohtani in the leg. White Sox manager Mike La Russa protested the decision, insisting it was not intentional, before also being ejected from the game. For what it is worth, Ohtani was OK to continue.
Perez equals catcher HR record
Salvador Perez clubbed a two-run homer to match Johnny Bench for the most home runs in a season by a primary catcher. Perez's first inning home run took his season tally to 45 and helped the Kansas City Royals to an early 2-0 lead, before losing 7-2 to the Oakland Athletics.
Thursday's results
Cincinnati Reds 1-0 Pittsburgh Pirates
Los Angeles Angels 9-3 Chicago White Sox
Oakland Athletics 7-2 Kansas City Royals
San Diego Padres 7-4 San Francisco Giants
Baltimore Orioles 3-2 New York Yankees
Philadelphia Phillies 17-8 Chicago Cubs
Tampa Bay Rays 5-2 Detroit Tigers
Houston Astros 12-1 Texas Rangers
Padres at Cardinals
Wild Card spots are on the line when the St Louis Cardinals (76-69), who have won five games in a row, host the San Diego Padres (76-70) in the National League.