Three home runs in the first inning ended up being not enough for the Houston Astros as they went down 8-5 at home against the Oakland Athletics on Saturday.

After Astros slugger Yordan Alvarez hit three home runs on Friday, he followed it up with another one less than 24 hours later, giving him six from his past six games.

But Alvarez was not one of the Astros to go deep in the first inning, with Aledmys Diaz, Kyle Tucker and Trey Mancini all taking turns hitting balls over the fence to jump out to a 4-1 lead before registering their third out.

From that point on, Athletics starting pitcher Cole Irvin tightened the screws, holding the Astros scoreless through the next six innings to allow his side a chance to fight back.

Oakland showed some power of their own in the middle frames, with Chad Pinder hitting a 348-foot wall-scraper to right field, before Seth Brown was much more convincing with his three-run, 432-foot launch in the fifth inning.

A double in the seventh inning gave Brown his fourth RBI, making it 7-5, with Alvarez's eighth-inning shot proving to be just a consolation.

It was Alvarez's 37th home run of the season, leaving him alone in third place league-wide, although he is still 20 home runs off leader Aaron Judge of the New York Yankees.

Woodruff dominates the Yankees

Milwaukee Brewers starting pitcher Brandon Woodruff put on a show at home against the New York Yankees, striking out 10 batters in eight innings on the way to a 4-1 win.

Woodruff allowed just one run – a solo home run to Josh Donaldson in the fourth inning – as only six Yankees reached base in the contest, with five hits and one walk.

With the bat, the majority of the damage was done by rising star Willy Adames, who became the second shortstop in the majors to hit 30 home runs this season with his three-run shot in the third inning. The other shortstop to hit 30 homers is Corey Seager, who was recently rewarded with a massive 10-year, $325million contract extension by the Texas Rangers.

Acuna carries the Braves

Ronald Acuna Jr drove in all four of the Atlanta Braves' runs in their 4-3 home win against the Philadelphia Phillies.

After two scoreless innings to begin the contest, Acuna broke the deadlock with a two-run, 427-foot bomb over the right-field wall, and then drove in another two runs with his next at-bat in the fourth inning when he doubled with two runners on base.

Both sides received solid starting pitching performances, with Philly opting to ride their ace Aaron Nola deep into the game, letting him pitch seven full innings, while the Braves pulled Jake Odorizzi after allowing just one run in four-and-two-thirds innings, although he threw only seven fewer pitches than Nola's 99.

St Louis Cardinals pitcher Adam Wainwright and catcher Yadier Molina made their 325th career start together on Wednesday to establish a record for the most by a battery in MLB history. 

Fans at Busch Stadium waved towels with the number 325 as Wainwright opened the game with a first-pitch strike to the Milwaukee Brewers’ Christian Yelich. 

The previous record was held by Detroit Tigers pitcher Mickey Lolich and catcher Bill Freehan between 1963-75. 

Wainwright and Molina made their first start together on April 6, 2007, with Wainwright throwing seven innings of one-run ball in a 4-2 victory over the Houston Astros. 

''A lot has taken place in that time span and that's why I think this record is pretty darn cool,'' St. Louis manager Oliver Marmol said before the game. ''I don't see anyone coming close to ever reaching it again.'' 

The closest active pitcher-catcher pair is not even a third of the way to Wainwright and Molina’s mark as the Chicago Cubs’ Kyle Hendricks and Willson Contreras have made 105 starts together. 

Wainwright and Molina are unlikely to add too many more starts to their record as the 40-year-old Molina is planning to retire at the end of the season. 

The 41-year-old Wainwright has yet to decide on if he’ll pitch in 2023. 

The Chicago White Sox dominated with bat and ball on Thursday as they hammered the Oakland Athletics 14-2.

AL Cy Young Award co-favourite Dylan Cease was on the mound for the White Sox and was at his dominant best, keeping the Athletics scoreless through the first six innings as he racked up nine strikeouts while giving up just three hits and two walks.

His six shut-out innings lowered his ERA for the season to 2.06, trailing only Houston Astros ace Justin Verlander, but with Verlander currently out injured, Cease has now made four more starts, and could pull away in the race for the league's best pitcher if his rival cannot return soon.

On offense, it was clearly the best game in the season for White Sox third-baseman Yoan Moncada as he went five-for-six at the plate. He had home runs in each of his first two at-bats, before following them with a single, a double and another single, getting out for the first time in the ninth inning.

Second-baseman Romy Gonzalez also proved to be a tough out, with his first four at-bats resulting in two singles, a double and a home run on his way to finishing four-for-five at the dish.

Seby Zavala, Elvis Andrus, Jose Abreu and A.J. Pollock also finished with multiple hits as the White Sox racked up 21 as a team, while the Athletics could only muster six.

With the win, the White Sox are now one-and-a-half games behind the Cleveland Guardians for the lead in the AL Central.

Molina turns back the clock in Cardinals loss

Future Hall-of-Fame catcher Yadier Molina hit two home runs in the St Louis Cardinals' 11-6 home loss to the Washington Nationals – doubling his total for the season.

Molina only had two home runs from 219 at-bats heading into the contest, but went two-for-four at the plate, hooking two balls over the left-field wall.

But the Cardinals pitching staff could not keep the Nationals off the board, with six Washington players collecting at least two hits each, led by the ninth batter in their lineup, Alex Call. Call finished four-for-five at the plate, including a home run and a double as he drove in five runs.

Burnes burns the Giants

Milwaukee Brewers ace Corbin Burnes had his way with the San Francisco Giants as he carried his side to a 2-1 victory in the first leg of Thursday's double-header.

Burnes pitched eight of the nine innings, allowing just three hits and no walks, while striking out 14 batters. It is the ninth time Burnes has struck out at least 10 batters in a game this season, and while it is a season-high, he finished one off his career-high of 15.

Back-to-back doubles in the fourth inning was the source of all Milwaukee's runs, with Christian Yelich bringing home Jace Peterson, before Yelich scored on a Hunter Renfroe hit.

It was a blast from the past for the St. Louis Cardinals in their 18-4 blowout win against the Pittsburgh Pirates on Sunday, with future Hall-of-Famers Albert Pujols and Yadier Molina the stars of the show.

It became uncompetitive early on after the Cardinals piled on seven runs across the opening two frames, and another four in the fourth.

Up 11-0 in the fifth inning, Pujols was brought in as a pinch-hitter, and he crushed the second pitch he saw for a 425-foot home run to left-field.

Pujols' day would not end there as he came up to bat again in the ninth inning with two runners on base, and he launched another home run to make it 18-0.

Not wanting to waste the performance of a real pitcher to close the game, the Cardinals brought in 39-year-old catcher Molina to handle the final inning. It was his first career pitching appearance.

He would give up four runs, including a home run to the very first batter he faced, before getting his third out from a deep fly-ball to center-field.

Both Pujols and Molina are members of the Cardinals only two World Series-winning teams since 1982 – in 2006 and 2011 – and will likely have their numbers retired by the club when they hang up their cleats.

All 10 Cardinals players to take an at-bat finished with at least one hit, while Tommy Edman, Nolan Gorman and Brendan Donovan collected three hits each.

After starting pitcher Steven Matz was withdrawn due to injury before retiring a single batter, Angel Rondon came in with a terrific performance out of the Cardinals bullpen, pitching five scoreless innings, striking out four while giving up just one hit and three walks for his first career win.

Dodgers error gifts Phillies the win

The Los Angeles Dodgers needed just one more out to secure a 3-2 extra innings win against the Philadelphia Phillies, but could not field a routine ground-ball.

After Trea Turner's base hit gave the Dodgers a lead in the top of the 10th inning, Evan Phillips was able to get two Phillies out, with runners on second and third.

While a base hit would have won it, Alec Bohm instead hit one along the ground straight to second-baseman Max Muncy, but as he fumbled the ball and was too late to get the out at first base, both runners came home to win the game.

White Sox wake up late

Chicago White Sox starting pitcher Michael Kopech had a perfect game through five innings, but his side needed a late rally to pull out a 5-0 win in the second game of their double-header against the New York Yankees.

Despite Kopech's heroics – finishing his career-long start with seven full innings pitched for six strikeouts, one hit and two walks – the scores were tied at 0-0 heading into the eighth frame.

Yankees set-up pitcher Jonathan Losaiga had no luck getting through the inning unscathed, giving up four hits and two earned runs before getting pulled with runners still on first and second. Miguel Castro could not get the Yankees out of trouble, giving up a three-run homer to Tim Anderson as the very next batter.

Clayton Kershaw and Mookie Betts starred for the Los Angeles Dodgers swept a double-header on Saturday against the Chicago Cubs.

Kershaw dominated the opener, giving up only five hits and striking out two over 81 pitches in seven innings, as the Dodgers won 7-0.

Betts shone in the night game, smashing a three-run double in the second inning and a two-run homer in the ninth to secure a 6-2 win.

Tyler Anderson struck out seven and gave up four hits over 80 pitches in five innings as the Dodgers claimed a fifth straight win.

They moved to 18-7 for the season and lead a strong National League West division, with every team holding a record at .500 or over.

Flores leads Giants to win over Cards

Wilmer Flores hit a grand slam in the first inning and finished with a career-high six RBIs as the San Francisco Giants beat the St. Louis Cardinals 13-7.

Logan Webb struck out seven but gave up eight hits and four runs over 84 pitches in five innings, while Mauricio Dubon and Darin Ruf also hit home runs for the Giants.

Yadier Molina reached 1000 career RBIs and Dylan Carlson added a three-run homer, but it was not enough as the Cards had their three-game winning streak ended.

Polanco propels Twins to victory

Jorge Polanco led the Minnesota Twins as they sent the Oakland Athletics to their eighth consecutive defeat, claiming a 1-0 win.

Polanco had three of the Twins' five hits on the night from four at-bats, including a monster home run in the sixth inning, his third for the year.

Minnesota pitchers combined to strike out 15 while allowing three hits, as they maintained their lead atop the American League Central.

Albert Pujols looks to be preparing for his final MLB season after returning to the St. Louis Cardinals, who hope he can help take them back to the World Series.

Future Hall of Famer Pujols has signed a one-year, $2.5million contract back in St. Louis, where he started his career in 2001.

In 11 seasons with the Cardinals, the 42-year-old won three National League MVPs, made nine All-Star Game appearances and claimed two World Series titles.

Now, after nine and a half seasons with the Los Angeles Angels before ending last year on the Los Angeles Dodgers, he is ready for one final push.

"This is it for me," Pujols said. "This is my last run."

Pujols appears set to play in a part-time role, as a designated hitter against left-handed pitchers and as a late-game pinch-hitter.

He added: "I think I am here for a reason. They believe I can still play this game."

Pujols may no longer be the difference-maker he was in those two title runs, but the Cardinals have not added to their 11 World Series wins since then, losing to the Boston Red Sox in 2013.

Yadier Molina, the 39-year-old catcher who was a team-mate for both championships and has spent his entire career in St. Louis, is delighted to be reunited with Pujols.

"I'm happy for him to be here," he said. "It's going to be a fun year. We've only got one thing in mind – winning another championship."

The San Francisco Giants reclaimed the National League (NL) West lead with a dramatic 3-2 walk-off victory over rivals and World Series champions the Los Angeles Dodgers.

Sole possession of top spot was on the line as the Giants and Dodgers clashed in a heavyweight MLB showdown in San Francisco on Friday.

The score was deadlocked at 2-2 until a bizarre walk-off throwing error lifted the Giants past the Dodgers in the 11th inning.

With the bases loaded in the 11th and two outs, Buster Posey appeared to have hit an inning-ending groundout, but Trea Turner's throw went wide of Will Smith, whose toe came off the bag.

Posey was initially ruled safe, and it stayed that way despite a lengthy Dodgers (85-50) review – the Giants (86-49) moving back to the top of the NL West again.

Comeback of the year?

The Toronto Blue Jays emerged from the jaws of defeat in stunning fashion, somehow conquering the Oakland Athletics 11-10. Toronto – chasing the last Wild Card spot – trailed 8-2 entering the eighth inning at home to fellow playoff hopefuls the A's. Lourdes Gurriel Jr. hit a game-tying grand slam after a two-out rally. Mark Canha's two-run homer restored Oakland's advantage in the top of the ninth, but Marcus Semien delivered an incredible walk-off three-run homer in the bottom of the inning. Gurriel became just the third Blue Jays player ever to hit three grand s lams in a season after Edwin Encarnacion (2015) and Darrin Fletcher (2000).

The Detroit Tigers lit up the Cincinnati Reds 15-5 behind Dustin Garneau's two-run homer and solo shot, plus Robbie Grossman's three-run blast.

Kyle Schwarber hit a lead-off homer in the opening inning to fuel the Boston Red Sox's 8-5 victory at home to the Cleveland Indians. Hunter Renfroe added a three-run homer for the Red Sox, who have won three straight games.

Keuchel's woes continue

Dallas Keuchel struggled again as the Chicago White Sox went down 7-2 to the Kansas City Royals. Keuchel allowed six runs in three innings – the 2015 American League (AL) Cy Young winner has a 7.26 ERA through his past 11 starts. He gave up five earned runs, seven hits and two walks with just one strikeout against the Royals.

Arenado homers twice as Wainwright and Molina celebrate milestone

St Louis Cardinals star Nolan Arenado recorded his 21st multi-homer game since entering the majors in 2013 – tied for the second most alongside Bryce Harper in the NL in that span, behind Giancarlo Stanton (22). The Cardinals crushed the NL Central-leading Milwaukee Brewers 15-4. Cardinals team-mates Adam Wainwright and Yadier Molina started together for the 300th time – the fourth most prolific battery in history.

Friday's results 

Chicago Cubs 6-5 Pittsburgh Pirates
New York Yankees 4-3 Baltimore Orioles
New York Mets 6-2 Washington Nationals
Toronto Blue Jays 11-10 Oakland Athletics
Boston Red Sox 8-5 Cleveland Indians
Detroit Tigers 15-5 Cincinnati Reds
Tampa Bay Rays 5-3 Minnesota Twins
Miami Marlins 10-3 Philadelphia Phillies
Kansas City Royals 7-2 Chicago White Sox
St Louis Cardinals 15-4 Milwaukee Brewers
Colorado Rockies 4-3 Atlanta Braves
Los Angeles Angels 3-2 Texas Rangers
Seattle Mariners 6-5 Arizona Diamondbacks
Houston Astros 6-3 San Diego Padres
San Francisco Giants 3-2 Los Angeles Dodgers

A's at Blue Jays

With both teams vying for a Wild Card berth, the Blue Jays (71-62) and Athletics (74-61) will continue their series on Saturday. Jose Berrios will start for the Blue Jays as the A's counter with Paul Blackburn.

Fresh off agreeing to a one-year extension to remain with the St. Louis Cardinals, longtime catcher Yadier Molina announced he plans to retire following the 2022 season.

Molina verified speculation that the 2022 campaign would be his last at a press conference prior to St. Louis' home game against the Detroit Tigers on Wednesday. The Cardinals announced on  Tuesday that the 10-time All-Star would be returning next season on a one-year deal.

The 39-year-old has spent his entire 18-year career with St. Louis, though a return in 2021 was not finalised until he and the Cardinals were able to agree to a one-year, $9million contract just prior to the start of spring training. Molina said he wanted to avoid a similar situation this winter and informed his agent to begin negotiations as soon as possible.

"That's why my agent and myself came to [president of baseball operations John Mozeliak] and told them I want to stay here," Molina said. "I want to get it done this early and not put this on the organisation in free agency again, because it's going to be my last year and I want to finish here with this great organisation."

A key member of the Cardinals' last two World Series championship teams in 2006 and 2011, Molina's 2,120 career games played are the third-most in franchise history behind only Hall of Famers Stan Musial and Lou Brock. He holds the major league record for most games as a catcher with one team at 2,081, and his nine Gold Gloves trail only Ivan Rodriguez (13) and Johnny Bench for the most by a catcher.

"It gives me great pleasure to announce that Yadier Molina will continue his franchise legacy for another season in 2022," Cardinals chairman Bill DeWitt, Jr. said in Tuesday's press release. "Yadi has continued to play at an All-Star level this season and has already established himself among the greatest players to have ever worn the birds on the bat."

Molina has started 95 of the Cardinals' 124 games behind the plate this season and ranks third on the team with 51 RBIs to go along with a .259 average and eight home runs.

Yadier Molina has agreed to terms on a new deal to extend his St Louis Cardinals career into an 18th MLB season.

The 38-year-old catcher's new contract was announced by the Cardinals on Monday.

Molina made his MLB debut with the Cardinals in 2004 and has gone on to win two World Series with the team, while being named an All-Star nine times.

"We are excited to announce that we have agreed to terms with Yadier Molina on a new contract!" the Cardinals wrote on Twitter.

"We will have more details tomorrow on Yadi continuing his Cardinals legacy."

Reports said Molina, who was a free agent, had agreed to a one-year extension with the Cardinals.

Molina's 2,025 games for the Cardinals ranks as the third most for the team, behind Stan Musial (3,026) and Lou Brock (2,289).

He is sixth for hits (2,001), seventh for RBIs (932), 10th for home runs (160) and 22nd for runs scored (713).

The Cardinals made the MLB playoffs in 2020 before falling to the San Diego Padres in the National League (NL) Wild Card Series.