Top overall seed Alabama were ousted from the NCAA tournament Sweet 16 after an upset 71-64 loss to San Diego State on Friday.

The Crimson Tide were well below their best in a sloppy performance with 14 turnovers, shooting three-of-27 from beyond the arc.

SDSU's Darrion Trammell scored 21 points as San Diego progressed to the Elite Eight for the first time.

Trammell led the way offensively for the Aztecs, while Nathan Mensah had eight rebounds and five blocks, while Lamont Butler had three steals, four rebounds and four assists.

For Alabama, top-five NBA Draft prospect  Brandon Miller scored nine points with 11 rebounds but committed six turnovers and shot three-of-19 from the field, including one-of-10 from three-point range.

Crimson Tide guard Mark Sears scored 16 points with 10 rebounds but shot none-of-five from beyond the arc.

"Everybody is really disappointed in the loss," Alabama coach Nate Oats said. "It ended too soon."

Midwest regional top seed Houston were also eliminated in the Sweet 16 on Friday after losing 89-75 to Miami.

Hurricanes guard Nijel Pack led the way with 26 points including seven-of-10 three-pointers as Miami made 11 of their first 22 attempts from beyond the arc.

Miami will take on Midwest second seed Texas in the Elite Eight after the Longhorns won ___ over the Xavier Musketeers, with Tyrese Hunter scoring a team-high __ points with __-of-__ three-pointers.

South regional six seed Creighton defeated Princeton 86-75 to set up a Elite Eight meeting with SDSU, after Ryan Kalkbrenner and Baylor Scheierman scored 22 and 21 points respectively.

Hall of Fame Michigan State head coach Tom Izzo earned his 15th trip to the Sweet 16 after eliminating two-seed Marquette 69-60 in Sunday's second round of the NCAA Tournament.

The Spartans rode a 23-point performance from senior point guard Tyson Walker, while Joey Hauser – brother of Boston Celtics wing Sam Hauser – collected 14 points and 10 rebounds.

As well as pulling into a tie for the sixth-most Sweet 16 appearances in head coaching history, Izzo also claimed the record for the most ever NCAA Tournament wins as the lower seed, with this his 16th.

He is one more Sweet 16 trip away from tying Louisville legend Denny Crum for the fifth-most, with only North Carolina's Roy Williams (19), Syracuse's Jim Boeheim (20), Michael Jordan's North Carolina coach Dean Smith (21) and Duke's Mike Krzyzewski (26) having more.

The seven-seed Spartans will next face three-seed Kansas State after they won the battle of the Wildcats 75-69 against six-seed Kentucky.

Reigning National Player of the Year Oscar Tshiebwe was monstrous with 25 points and 18 rebounds, while projected first-round draft pick Cason Wallace impressed with 21 points (nine-of-11 shooting), nine rebounds, four assists and two steals.

But their performances were not enough to lift Kentucky to the victory, as diminutive five-foot-eight point guard Markquis Nowell dropped a game-high 27 points and nine assists to carry Kansas State through.

Following his massive 28-point, 13-rebound showing in his side's opening-round win, Connecticut Huskies center Adama Sonogo starred again with 24 points (11-of-16 shooting) and eight rebounds in a 70-55 win over the Saint Mary's Gaels.

After Marquette, the top seed to fall Sunday was the three-seed Baylor Bears. Despite 30 points from Baylor guard L.J. Cryer, the Creighton Bluejays received a game-winning 30 points from Ryan Nembhard in the 85-76 triumph.

Nembhard is the younger brother of Andrew, who has been a rookie standout for the Indiana Pacers this season.

Following their stunning upset of one-seed Purdue, where they became the second 16-seed to ever advance past the first round, the Fairleigh Dickinson Knights were sent packing 78-70 by the nine-seed Florida Atlantic Owls.

Three-seed Xavier were in control throughout their 84-73 win against Pittsburgh, five-seed Miami prevailed 85-69 over four-seed Indiana, and four-seed Gonzaga sent six-seed TCU home 84-81.