Manchester United will face European debutants Granada in the quarter-finals of the Europa League and cannot now meet Arsenal until the final.

The draw for the last eight on Friday kept the two remaining Premier League giants apart.

United claimed a 1-0 win at Milan on Thursday to advance 2-1 on aggregate and their reward is an apparently kind draw against LaLiga's Granada, winners over Molde.

If United advance, they could have a replay of the 2016-17 final in which they defeated Ajax, who take on Roma for the right to play the Red Devils or Granada.

Ajax were too strong for Young Boys, while Roma dumped out Shakhtar Donetsk.

Arsenal, who knocked out Olympiacos despite losing at home, will be wary of their quarter-final opponents Slavia Prague.

Slavia have already eliminated Leicester City and Rangers, and have now been paired with the 2018-19 finalists, visiting Emirates Stadium before hosting the reverse fixture.

Arsenal's half of the draw is completed by Dinamo Zagreb and Villarreal.

Dinamo defeated Tottenham in a stunning second-leg comeback on Thursday and could get the chance to complete a north London double if they meet the Gunners.

A meeting between Arsenal and Villarreal would also have significance, with the Spanish outfit coached by Unai Emery, Mikel Arteta's predecessor and a three-time Europa League winner with Sevilla.

Emery's men swept aside Dynamo Kiev in the last 16.

Quarter-final draw:

Granada v Manchester United
Arsenal v Slavia Prague
Ajax v Roma
Dinamo Zagreb v Villarreal

Semi-final draw:

Winner of QF 1 v Winner of QF 3
Winner of QF 4 v Winner of QF 2

Mikel Arteta appreciates the pressure is always on at Arsenal as he prepares his squad for a pivotal game against Benfica that will shape the remainder of their season.

Arsenal go into the second leg against their Portuguese opponents with the Europa League last-32 tie delicately balanced following a 1-1 draw in Rome. 

The English club did grab an away goal in the first meeting, though are without the benefit of home advantage for the return fixture. Due to coronavirus travel restrictions, the game is to be played in Greece. 

Out of both domestic cups and languishing down in 10th place in the Premier League, Europe offers the Gunners their last chance of success in Arteta's first full season in charge. 

"I always feel that it (pressure) is [on me], every time you're playing in a competition and you can go out you know the consequences and with this club [the aim] is always to win the competition that you are in, so that doesn't really change much," Arteta said.

"It's a big season and a really important [game], mentally and confidence-wise.  

"It's going to dictate if we're in another competition or not for a few more weeks. This is really what we need. It's a really tough opponent.  

"It's a Champions League team who have been playing in these types of games for many years with a manager with huge experience. For us, it's a final."

With an 11-point gap to fourth-placed West Ham and just 13 games remaining, it seems improbable that Arsenal can qualify for next season's Champions League through the domestic route. 

The Europa League, therefore, takes on added importance. They have won on each of their previous two visits to Greece as well, albeit both against Olympiacos, including a victory in this same competition a year ago. 

"I think while mathematically everything is possible, in football you have to try so hard," Arteta said. "We're going to do that in the league for sure.

"It's true that the Europa League gives you a completely different route and is a competition that we want to carry on playing, and try to win it.  

"Tomorrow is another opportunity to make a step forward. The better we are in the Europa League, the better we're going to be performing in the league and vice-versa. We need to be alive in both competitions."

Arteta revealed Thomas Partey is "very close" to a return from a hamstring injury, meaning the midfielder could feature against Benfica. Rob Holding, however, is ruled out due concussion protocols. 

Ajax goalkeeper Andre Onana has been suspended for 12 months by UEFA due to a doping violation, the Eredivisie club have confirmed.

Ajax and Onana will appeal to the Court of Arbitration for Sport (CAS) to overturn the ban, imposed after an out-of-competition test in October 2020 found the substance Furosemide in the player's urine.

The club said the test result was due to Onana, 24, mistakenly taking Lasimac – a drug prescribed to his wife – when he felt unwell.

UEFA therefore accepted Onana "had no intention of cheating", an Ajax statement read.

It added: "However, UEFA believes, on the basis of the applicable anti-doping rules, that an athlete has a duty at all times to ensure that no banned substances enter the body."

The suspension is effective from Friday and applies to "all football activities, both national and international".

Ajax managing director Edwin van der Sar said: "We explicitly renounce performance-enhancing drugs, we obviously stand for a clean sport.

"This is a terrible setback, for Andre himself but certainly also for us as a club. Andre is a top goalkeeper, who has proven his worth for Ajax for years and is very popular with the fans.

"We had hoped for a conditional suspension or for a suspension much shorter than these 12 months, because it was arguably not intended to strengthen his body and thus improve his performance."

Cameroon international Onana has been a key man for Ajax since his debut in 2016-17, playing his part in runs to the Europa League final and Champions League semi-finals.

His absence is the latest blow to Ajax, who earlier confirmed they would be unable to correct the administrative error that saw Sebastian Haller left out of their Europa League squad.

Haller, signed from West Ham for a club-record €22.5million last month, was not included in Ajax's initial list for European competition for the second half of the season.

Coach Erik ten Haag described the mistake as "an administrative error with major consequences" and "an incredible setback" for the player, although he confirmed Ajax would be addressing the matter with UEFA.

However, a further club statement has now confirmed UEFA sent "a final message" to say Haller could not be added to the group.

Haller has scored two goals in his first seven games for Ajax in all competitions.

"There is a spirit in the team but also the club – a dynamic in the last months and last years. That should lead us one day to a title, that's our big goal."

Bayer Leverkusen are one of Germany's biggest clubs, but not since the 1993 DFB-Pokal have they celebrated silverware.

Leverkusen have come close on numerous occasions in the Bundesliga – runners-up in 1997, 1999, 2000, 20002 and 2011, while they also reached the 2002 Champions League final, succumbing to Zinedine Zidane's iconic volley in Glasgow.

There were also runners-up appearances in the DFB-Pokal – 20002, 2009 and 2020. But an exciting and entertaining Leverkusen, even in the post-Kai Havertz era, are on the right track amid Bayern Munich's domestic and European dominance.

Leverkusen sporting director Simon Rolfes told Stats Perform News: "It's not easy if you're playing with the best team in the world – Bayern – but we have made a step forward and quite close to the top. We want to go forward. If it happens this year, fantastic. But we want to proceed and develop the squad, and mentality."

When star Havertz left for Chelsea at the start of the season in a transfer that could rise to €100million, and Kevin Volland joined Monaco, it left a noticeable hole at BayArena, where the pair scored 30 goals across all competitions in 2019-20.

But led by prodigy Florian Wirtz and a thrilling core of players, including Moussa Diaby, Leon Bailey and Nadiem Amiri, Leverkusen are continuing to challenge this term.

Leverkusen are third in the Bundesliga – three points behind RB Leipzig and 10 adrift of reigning champions Bayern – while Peter Bosz's side are preparing to face Young Boys in the Europa League last 32 and Rot-Weiss Essen in the DFB-Pokal round of 16.

With Havertz having departed, Leverkusen have a better goals/game ratio (2.5) through 26 games across all competitions this season, compared to 1.8 in 2019-20. The club have also improved defensively – goals conceded/game (1.0) and expected goals against (1.0) are better than last term (1.3) and (1.4) respectively.

Collecting 32 points, Leverkusen have played the best first half of a Bundesliga season for seven years – they collected 37 points at this stage in 2013-14.

Leverkusen have also exceeded their xG value of 23.1 to almost nine goals (8.9) – only Bayern have a greater margin between goals and xG (13.9). 

"In general yes because it's a chance for other players to develop and take more responsibility in the team and on the pitch," Rolfes, who was appointed in 2018, said when asked if he was always confident following the exits of Havertz and Volland. "We had the view that there could be other players who could take a step forward. The only thing for sure is Havertz is a world-class player, a fantastic guy and player. It's very difficult to replace him, so we said, it's not our direction to find a replacement for Kai because you will never find that replacement.

"We said okay, we will give our own players the chance to grow, this strategy works out very fast. It's always a risk for sure, but we have the confidence in those players to make a step forward, and also the team. If your superstar is gone, everyone knows we have to give more.

"We try to build-up, play offensive with ball possession, straightforward – the kind of style we showed against Borussia Dortmund [2-1 on January 19] is what we want. We want to have the ball, a lot of clubs and trainers are speaking to play without the ball, in Germany it's very popular, but we want to have the ball and want players who want the ball."

The emergence of teenage sensation Wirtz, and development of Diaby, Bailey, Edmond Tapsoba and Amiri, has further highlighted Leverkusen's successful recruitment and philosophy, which has become synonymous with German clubs.

"You have to have a clear strategy," Rolfes, who made almost 400 appearances for Leverkusen between 2005 and 2015, said. "A clear strategy of recruitment but also your playing style. That's really important for players but also the success of a club – both are strongly connected. For your playing style, you have to sign the right players. Then you have the chance that the players adapt quicker and develop better in your system because they feel comfortable in the way of playing. That's crucial.

"We know the Bundesliga, financially solid, but we are not at the top that we can sign every player, we have to develop players. The strategy is to recruit good players for our style and develop them to the top. Some clubs in Germany are quite successful with this."

"We are focusing on that talent and try to find them," he said. "We analyse millions of data with artificial intelligence, to pre-select and be early. It's not because we know players other clubs do not know, maybe 20 years ago, but everything is transparent. But you have to find them a bit quicker, but also clear in your playing style and what can they develop with your training work, in which areas they can develop in weak points. Because we are not signing players where everything is 100 per cent, we know they have weak points, but we know we have to work with them on that."

Data and AI continue to play a huge role in football, with Rolfes adding: "It's very important and because the data will be better and better, it will become much more important in the future because you will get better results. We are working with our own team on scouting, preparing for next matches – just in our daily work."

The likes of Michael Ballack, Toni Kroos, Bernd Leno and Havertz have all made names for themselves at Leverkusen, and Rolfes continued: "We count on the young players [at Leverkusen]. We give them trust and the opportunity to play. For example, Wirtz, we give him the chance to replace Havertz and not sign another star to put in front of him. That is one thing.

"We have a very professional environment, we really take care of the guys – try to develop them, work on the pitch and prepare them for top football. We have an advantage that the media surrounding is not so big here. That's good for young players to have a familiar environment where they feel very comfortable and less stressful, then try to reach the best level on the pitch."

Wirtz is the heir apparent to Havertz, having made an immediate impact after the 17-year-old swapped Cologne for Leverkusen in 2020.

Having made his debut in May 2020, Wirtz became the youngest goalscorer in Bundesliga history the following month, finding the net in a 4-2 defeat to Bayern after coming on as a substitute. Dortmund's Youssoufa Moukoko has since snatched that record.

Among all players with at least 50 dribbles in this season's Bundesliga, only Augsburg's Daniel Caligiuri has a better dribbles success rate (70 per cent) than Wirtz (65 per cent). 

Wirtz is one of 50 players born in 2003 or earlier to appear in Europe's top five leagues this season. Those 50 players have collected a total of 14 goal involvements – with seven of them coming from Wirtz. 

Among all players in Europe's top five leagues born in 2003 or earlier, Wirtz played the most minutes in all competitions this season (1,579) and had the most goal involvements in all comps (11 – six goals and five assists). 

"I saw him for the first time at 13. Now I have to say, he is playing Bundesliga the same way he was playing at 13, 14, 15, 16 – I followed him all the years. I always said okay, that's the player for us, the player for Leverkusen. That was not a surprise for me when he came to us and adapted very quick to our style," former Germany international Rolfes said.

"It was also one argument I said to him during the transfer. I said, 'you are a player for us, you will develop your skills and strengths much better because that's what we need in our style'. His development is fantastic."

Like Havertz, Bailey could be the next Leverkusen star to leave amid constant speculation over his future.

The 23-year-old winger, who has scored four goals and supplied five assists in the 2020-21 Bundesliga so far, has been linked with the likes of Manchester United and Manchester City and Rolfes is unwilling to sell the Jamaican to just any club.

"He's played a fantastic season," Rolfes said. "He struggled a bit last season, but he is performing at a very high level. A good guy in the squad. He has a chance to score goals for sure. A fantastic technique. That's part of lives also, to sell players but we want to sell to the top eight clubs in the world, but not to other clubs. Sometimes a player will leave us. We have a contract with Bailey but we are quite relaxed."

Diaby is another prime example for Leverkusen, where the accelerating Frenchman has 561 sprints in the league this season, more than any other player. 

The former Paris Saint-Germain speedster has been involved in 15 goals in all competitions in this season (in 26 games) – with his next goal involvement the 21-year-old would already reach his value from his first season in Leverkusen (16 in 39 games). 

"When we extended the contract until 2025, that was a really nice Christmas present to extend the contracts of Diaby, Tapsoba and Wirtz," Rolfes said. "[Diaby] is a key player of our squad. His acceleration and speed is outstanding. He has developed on scoring and assisting. To use his acceleration on a top, top level. He has potential to develop further. I'm very, very happy he is part of our squad."

Meanwhile, Timothy Fosu-Mensah could be the latest success story for Leverkusen, who also completed the signing of Netherlands Under-20 international Jeremie Frimpong from Celtic on Wednesday.

After joining Manchester United's academy in 2014, the 23-year-old called time on his Old Trafford stay in January, and Rolfes said: "He is not so young but the last two years, you had the feeling there was more in the box than there was in the last two years. That's interesting for us, to sign that kind of player where you have the feeling they can reach more. We want to help him.

"Timothy is a really good guy, ambitious guy. I like this. He has the ability, the physicality, very fast, a good technique. A lot of fundamental things that are important for our playing style. Then if the mentality and ambition isn't right, then let's work on that to develop you. I'm convinced Timothy can be the next example for our club."

Kai Havertz was dubbed the 'Crown Prince of German football' while at Bayer Leverkusen but the Bundesliga club have a new star now: Florian Wirtz.  

While his former club colleague has struggled so far to make an impact at Chelsea, Wirtz - the latest young gem to come through at Leverkusen - is dazzling for Peter Bosz's team, who remain ensconced in the top four despite defeats either side of the mid-season break in Germany's top flight. 

The 17-year-old did not wait long to suggest he could be the heir apparent, either. Having made his debut in May 2020, he became the youngest goalscorer in Bundesliga history the following month, finding the net in a 4-2 defeat to Bayern Munich after coming on as a substitute. Youssoufa Moukoko has since snatched that record away.

This season, Wirtz has gone from the periphery to centre stage, scoring twice and providing four assists in 13 appearances. His transition from promising talent to first-team regular has been swift, leading to comparisons to Havertz, the playmaker who swapped the BayArena for Stamford Bridge.

However, for Bosz, while both players have huge potential, the duo differ in so many ways.

"I never compare players with each other because that is impossible. There is no player like the other," Bosz told Stats Perform News. "You can't compare them. That's not possible.

"I also won't do that with Florian Wirtz, because he has his own style. He is different from Kai Havertz, who is more of a striker. Florian Wirtz, as far as I am concerned, is a midfielder, so you can't compare them.

"Also, you can't compare them physically; Kai is 1.92metres (6ft 3in), Florian is shorter. One is left-footed, the other one right-footed. They both have their own style. But both of them are very good. Both are very talented. Both have a huge career ahead of them.

"And Florian is only 17 years old. What he has shown though in the Bundesliga already is something special."

Wirtz has been a part of a Leverkusen squad that has impressed so far in this campaign, both at home and abroad. 

Despite a first defeat to Bayern Munich before the mid-season pause in Germany, Leverkusen gathered 28 points from their opening 13 league games. Only three times have they managed to collect more points across the same period - and on each of those occasions they went on to finish in the top four.

In the Europa League, Die Werkself finished top of Group C to qualify for the last 32 in style, winning five of their six round-robin fixtures. Having reached the quarter-final stage of the competition last year, when they lost 2-1 to Inter, hopes are high they can go further this time around. 

But while there has been much to please Bosz and Leverkusen's supporters so far, the Dutch coach insists there is still plenty more to come from his squad.

"Everyone still has some space to improve," he said, insisting no player has reached a nine out of 10 yet. "The difference to last year is that we are very consistent now.

"We deliver stable performances. It means that we concede less goals. We stand more compact on the pitch.  

"But we have also lost important players. Kai Havertz went to Chelsea, Kevin Volland to Monaco. I think that our team spirit has improved. This is the biggest step ahead." 

Despite Havertz no longer being around, Leverkusen have been excellent going forward, with champions Bayern the only team to score more in the Bundesliga so far. Their attacking intent has not come at a considerable cost defensively either - only second-placed RB Leipzig have conceded fewer goals.

The emergence of Wirtz has been one of the factors in helping Leverkusen continue to progress as a club, even with those key departures in the previous transfer window.

"He's a very talented young player. He has a lot more to improve. But, you know, he's only 17," Leverkusen winger Leon Bailey told Stats Perform News about his talented young team-mate.

"He's still learning. But he has a lot of qualities that a lot of older players don't have yet. And that's something you can see clearly, and this is something that's special. 

"And I think, as the years go by, he will only get better. There is a lot more to come from him, as he understands more and get a lot more experience.  

"I would say he's very smart. He has a lot of quality when he's on the ball. And he has a great passing ability."

Bailey's assessment is backed up by Wirtz's output, with no Leverkusen player having created more chances from open play than his tally of 23. While his passing accuracy is perhaps lower than might be hoped for at 73 per cent, his touches in the opposing box (31) and passes into the final third (55) are examples of his forward thinking when in possession. 

Those risks have reaped their rewards this term too, considering his six goal contributions so far. Bosz clearly has faith in him, as only goalkeeper Lukas Hradecky and Moussa Diaby have played more minutes in the Bundesliga so far. 

Any suggestion of becoming the new Havertz may be wide of the mark, but the future looks bright for Wirtz, the latest jewel to emerge at Leverkusen. 

Son Heung-min scored his 100th goal for Tottenham in all competitions as he netted against Leeds United, with Harry Kane the provider once again.

The South Korea forward, who moved to north London in 2015, has been in sensational form in 2020-21, and moved onto 99 Spurs goals with a cool finish on the break at Liverpool in December.

Son drew a blank in his next three outings, failing to find the target as Spurs went down 2-0 to Leicester City, before he had a goal disallowed in an EFL Cup win at Stoke City and then only managed one attempt at goal in a 1-1 draw with Wolves on December 27.

However, after Wednesday's scheduled game with Fulham was postponed, his landmark effort came against Leeds on Saturday.

Kane – who has now assisted nine of Son's 12 Premier League goals this term – whipped in a brilliant cross from the right, which his strike partner swept home first time.

Son's strike put Spurs 2-0 up just before half-time, with Kane's penalty having put Jose Mourinho's men ahead.

With 169 goals to his name, Kane is the only Spurs payer to have netted more goals than Son since September 2015.

It was also the 13th time Kane and Son have combined for a goal this season, which is a joint-record in a single Premier League campaign.

Son has scored 65 of his 100 Spurs goals in the Premier League – 35 coming from his right foot, 25 from his left, and the remainder with his head.

The former Bayer Leverkusen forward has also supplemented that tally with a further 33 assists, while he has scored 15 times in the FA Cup and EFL Cup.