Novak Djokovic has withdrawn from the Indian Wells Open, the tournament confirmed on Wednesday. 

World number one Djokovic was set to return to action at the rescheduled event after losing the US Open final to Daniil Medvedev in straight sets. 

However, the Serbian – one of two five-time winners of the competition alongside Roger Federer – has decided to pull out for an unspecified reason.

"I am sorry I won't get to see my fans in Indian Wells and play in the desert, my favourite place to go. I hope to see you next year!" Djokovic said in a statement. 

Tournament director Tommy Haas added: "We are disappointed that Novak will not be able to joins us at the BNP Paribas Open this fall. 

"We hope to see him back in Tennis Paradise next March to contend for a record-setting sixth title in the desert." 

Djokovic's defeat against Medvedev in Flushing Meadows ended his hopes of claiming a record-breaking 21st major title, the 34-year-old having already won the Australian Open, French Open and Wimbledon in 2021. 

He fell short in his aim to become the first man since Rod Laver in 1969 to win all four majors in a single season but has already booked his place at this year's ATP Finals. 

Fifth seed Filip Krajinovic made a comfortable start to his Sofia Open campaign on Wednesday, defeating Alexandar Lazarov 6-0 6-3.

Krajinovic was the only seeded player in action and he was dominant against home hope Lazarov, who is ranked 462 in the world.

The Serbian swept the first set without conceding a break point and finished the job by claiming the last four games in the second despite Lazarov putting up more of a fight.

Elsewhere, Krajinovic's compatriot Miomir Kecmanovic crashed out to Italian Gianluca Mager, who fired down 11 aces and forced 10 break-point opportunities to earn an impressive 7-6 (7-3) 6-3 win.

Australian James Duckworth, meanwhile, had to launch a comeback before ultimately prevailing 3-6 6-4 6-4 against Finland's Emil Ruusuvuori to book a round two match with Benoit Paire.

The number one seed and defending champion Jannik Sinner will begin his campaign on Thursday with a last-16 contest against Egor Gerasimov.

Second seed Gael Monfils will play Ilya Ivashka, who defeated Pablo Andujar in straight sets, with the winner to face Mager, who is the first man in the quarter-finals.

Alex de Minaur will also be in action against American Marcos Giron.

Emma Raducanu has been given a wildcard entry to the Indian Wells Open in her first tournament since winning the US Open.

The 18-year-old claimed a sensational triumph at Flushing Meadows earlier this month, becoming the first qualifier to take a major title.

Raducanu defeated fellow unseeded teenager Leylah Fernandez 6-4 6-3 in the final of only her second grand slam.

The Briton did not drop a set throughout her fairytale run and climbed from 150th in the WTA rankings to now sit 22nd.

And Raducanu's remarkable display has earned her the opportunity to enjoy further stateside success at Indian Wells, having missed the cut when the entry list was first announced during the US Open.

She still has an outside chance of making the WTA Finals in Guadalajara, with appearances planned at tournaments in Russia and Romania later in October.

Raducanu's hopes of another deep run at Indian Wells have been boosted by the absence of superstar pair Naomi Osaka and Ash Barty, who have both withdrawn from the event.

Former world number one Andy Murray earned a second-round clash with Casper Ruud at the San Diego Open after easing past lucky loser Denis Kudla in straight sets.

Murray – a three-time grand slam champion – defeated Kudla 6-3 6-2 in just over an hour, winning an outstanding 28 of 31 (90 per cent) first-serve points on Tuesday.

The 34-year-old Murray was also on top on return, converting three of four break-point opportunities against Kudla, to complete a comprehensive display.

Murray – currently ranked 116th in the world – will face second seed Ruud next at the ATP 250 tournament.

Elsewhere, Grigor Dimitrov was made to work for his 6-3 1-6 7-5 victory over Hungarian Marton Fucsovics.

Former world number three Dimitrov triumphed in two hours, seven minutes, confirming a spot in the second round, where he will face US Open semi-finalist Felix Auger-Aliassime.

Diego Schwartzman – the sixth seed – progressed with a 6-2 6-3 win over Italian qualifier Federico Gaio.

Young American Sebastian Korda beat Tommy Paul 6-3 5-7 6-1 in more than two hours, while ninth seed Lorenzo Sonego, Cameron Norrie and Lloyd Harris were also victorious.

Marcos Giron moved through to the second round of the Sofia Open, but needed 10 match points to overcome Jaume Munar 6-7 (2-7) 6-1 6-4.

Giron lost the first set in a tie-break, however, the American fought back in an encounter lasting nearly three hours on Tuesday.

Twenty minutes of match time came in the final game, which encompassed all of Giron's match points.

Munar successfully staved off the first nine and had seven break points of his own. Yet his resistance was finally broken as Giron prevailed at the ATP Tour tournament.

Next up for Giron is a meeting with Australian third seed Alex de Minaur.

Eighth seed John Millman enjoyed a more routine 6-2 6-4 victory over Mikael Ymer, while there were also victories for Laslo Djere, Dimitar Kuzmanov and Egor Gerasimov.

Brandon Nakashima has been one of the ATP Tour's hottest players throughout the hardcourt season, and he kept rolling Monday before a hometown crowd. 

The 20-year-old Nakashima rallied to defeat Italian veteran Fabio Fognini 6-7(5), 6-1, 7-5 in the first round at the San Diego Open, setting up a second-round matchup with top seed Andrey Rublev. 

After qualifying for the main draw at Wimbledon earlier this summer, Nakashima reached finals at Los Cabos and Atlanta in successive weeks, falling to John Isner in the latter finale. He then knocked Isner out of the US Open in the first round in straight sets. 

Monday, he won 80 per cent of the points on his first serve, dialling up eight aces to just one for Fognini, who also double faulted 11 times. 

Another Southern California native, Taylor Fritz, also advanced Monday, beating qualifier Salvatore Caruso 6-4 7-6 (2) to earn a second-round meeting with fourth seed Denis Shapovalov.

It was a welcome reprieve for the world number 39, who had lost five of his previous six matches dating to a quarter-final win over Reilly Opelka in Atlanta. 

Earlier, world number 24 Aslan Karatsev opened the day's action by defeating Federico Delbonis 6-1 7-5. 

Benoit Paire is through to the second round of the Sofia Open following a 6-4 7-5 win over seventh seed Alejandro Davidovich Fokina. 

The Frenchman - ranked no. 49 in the world - marked his debut at the ATP 250 event by ending a three-match losing run, progressing after one hour and 37 minutes on court. 

Paire, who recorded five breaks of serve en route to victory, will be up against either James Duckworth or Emil Ruusuvuori next. 

"[I am] happy about the win," Paire said in his on-court interview. "It was not easy. Alejandro is a very good player, so I had to be focused on my game. 

"I had to serve well and do my best and that is what I did and I am very happy and proud of my game today.  

"I played well in the first game, it was good for my confidence. The most important thing is to stay on my game and stay focused. I was solid today so I am very happy." 

Also in Monday's action, Adrian Mannarino was another seed to suffer an early exit, going down in straight sets to Gianluca Mager. 

Miomir Kecmanovic came through a tight two-set contest to knock out Adrian Andreev, including taking the opener via a tie-break. 

Wimbledon champion and world number one Ash Barty has withdrawn from this month's Indian Wells Open. 

The Australian has not played since her surprise third-round defeat to Shelby Rogers at the US Open last month. 

Barty follows four-time grand slam champion Naomi Osaka in pulling out of the California event, the final WTA 1000 tournament of the year. 

The 25-year-old had indicated after her defeat at Flushing Meadows that she planned to play at Indian Wells. 

Defending champion Bianca Andreescu heads a strong field, with world number two Aryna Sabalenka, Wimbledon finalist Karolina Pliskova, French Open champion Barbora Krejcikova, Olympic bronze medalist Elina Svitolina and last year's Australian Open champion Sofia Kenin all taking part. 

Three other previous winners – Simona Halep, Elena Vesnina and Victoria Azarenka – will also be present, along with teenager Leylah Fernandez, who reached the US Open final. 

Kim Clijsters saw her latest WTA Tour comeback ended by Hsieh Su-wei at the Chicago Fall Tennis Classic on Monday.

The four-time grand slam champion, playing in her first match of 2021, was defeated 6-3 5-7 6-3 in a contest lasting two hours and 18 minutes on Stadium Court.

Clijsters, who retired in 2012, made her return to the Tour last year, losing her three matches.

After knee surgery at the end of 2020 and having contracted COVID-19 this year, the 38-year-old at last made her first appearance of the season but was bested in a gruelling contest by Australian Open quarter-finalist Hsieh.

Speaking prior to her return in Chicago, Clijsters spoke of how she was drawing inspiration from Andy Murray, who continues on the ATP circuit despite two major hip surgeries.

"Seeing Andy Murray and the way he speaks about his comeback and everything, it's so motivating and it gives you a lot of energy too," she said. "To see him go through the things he's gone through and be open about the challenges of it and the belief that he has, I feel like it's something I can relate to."

Seeds Jessia Pagula, Danielle Collins and Veronika Kudermetova all progressed in Chicago on Monday, although home favourite Madison Keys had to retire from her match with Aliaksandra Sasnovich.

Naomi Osaka is going to play tennis again and expects to feed her itch to return to the tour "soon".

Osaka said in the wake of her shock US Open third-round defeat to teenager Leylah Fernandez that she would take a break from the sport.

"I honestly don't know when I'm going to play my next tennis match. I think I'm going to take a break from playing for a while," Osaka told her post-match media conference following that loss.

She subsequently pulled out of Indian Wells but the four-time grand slam champion, who withdrew from the French Open back in May to protect her mental health, does not anticipate her absence being an extended one.

"I know I'm gonna play again, probably soon because I kind of have that itch again," Osaka told HBO's 'The Shop'.

"But it wouldn't really matter to me if I won or lost. I'd just have the joy of being back on the court.

"Just to, like, you know, that I'm doing it for myself."

Explaining her unhappiness on the court, Osaka added: "I started to feel like that power was being taken away from me.

"And the way that I felt, like, I wasn't playing to make myself happy and I was more concerned about … what would people say about me.

"I used to love the competition and just being competitive. Like if I were to play a long match, the longer it was the more fun it was for me.

"And then I just started to feel – recently – the longer it was the more stressed out I became. But I just needed a break to go within myself."

John McEnroe promised Team World would bounce back after suffering a 14-1 thrashing by Team Europe at the Laver Cup in Boston.

Europe wrapped up a fourth consecutive Laver Cup triumph as Andrey Rublev and Alexander Zverev capped off a dominant performance.

Having won all four matches on Saturday, Europe needed just one more victory to again retain the trophy, preserving their record of having won each edition of the tournament.

That duly arrived as Rublev and Zverev prevailed against Reilly Opelka and Denis Shapovalov in their doubles clash.

They emerged 6-2 6-7 (4-7) 10-3 victors, to spark European celebrations.

Next year's match will be played in London, and Team World captain McEnroe said: "No one wins the Laver Cup, beats us, John McEnroe, five times in a row. You've got to keep going.

"Team Europe is a great team, no question, incredible team. They had good team spirit. We did, as well."

McEnroe, quoted on the Laver Cup website, added: "If you get a couple of different results, we could have put more pressure on them. But we just came up short in four tiebreakers. You win half those, it's totally different story. We gave it our best, but they were just too good."

Zverev reflected on Europe's win, saying: "The score says that it was 14-1, but it could have gone both ways a lot of the time.

"We [did] a lot of hard work for this victory throughout the whole week. The group of this team has been absolutely amazing.

"I think a lot of us came a lot closer together and to be honest I can't wait for London next year."

Hubert Hurkacz collected his fourth ATP Tour title after defeating Pablo Carreno Busta in straight sets at the Moselle Open.

The Pole did not drop a set on his way to the final and produced yet another impressive outing to down Carreno Busta 7-6 (7-2) 6-3 in just 82 minutes.

Carreno Busta did, however, take an early lead and have Hurkacz reeling from a break down in the first set but the 24-year-old, who defeated former world number one Andy Murray this week, responded efficiently.

Having come from 3-1 down to 4-4, Hurkacz did not look back as his sharp first serve caused Carreno Busta all sorts of problems, most notably to secure the first-set tiebreaker with ease.

The pair continued to exchange breaks at the beginning of the second set but Hurkacz played well from the baseline and held serve to clinch his first trophy outside of the United States.

His victory means he holds a 4-0 record in ATP Tour finals and also saw him inflict revenge on Carreno Busta, who won the previous head-to-head clash in Cincinnati last month.

Hurkacz will be looking for doubles glory on Sunday as well, as he teams with international compatriot Jan Zielinski.

Anett Kontaveit sealed a second title of the season as she overcame Maria Sakkari in straight sets at the Ostrava Open.

The unseeded Estonian, who is ranked 30th in the world, saw off fourth seed Sakkari 6-2 7-5 to claim the trophy in the Czech Republic.

Kontaveit has now won two tournaments in four weeks, having won in Cleveland last month to end a four-year wait since winning her first title in 2017.

This was Sakkari's first final in over two years as well, but Kontaveit cruised past the Greek in just over an hour and a half as she did not drop a set all week.

That flawless level of tennis saw her eliminate Petra Kvitova, Paula Badosa and Belinda Bencic en route to the final, where the 25-year-old faced only one break point as she powered to a comfortable victory over a player who reached semi-finals at the French Open and US Open this year.

Sakkari managed more of a fight in the second set, where she battled for her sole break point, but Kontaveit breezed past any pressure and kept her serve to maintain control.

Sakkari, who is likely to move into the top 10 despite losing, had boasted a 5-3 head-to-head record in main-draw clashes between the pair coming into Sunday's final, but 23 unforced errors outnumbered the 20 winners from her racket as Kontaveit collected her most notable title to date.

Kwon Soon-woo claimed his maiden ATP Tour title with a straight-sets defeat of James Duckworth at the Astana Open.

The South Korean came out on top in the battle of the unseeded first-time finalists on Sunday, winning 7-6 (8-6) 6-3 in Nur-Sultan.

Kwon won 86 per cent of points behind his first serve and came from behind in both sets to be crowned champion.

Australian Duckworth failed to convert three set points in a tie-break and Kwon made him pay, grasping his first opportunity to go a set up.

Kwon was broken in the first game of the second set, but the battling world number 82 hit straight back to draw level.

Duckworth, who had not dropped a set en route to the final, was broken again to trail 4-2 and he was unable to find a way back as the 23-year-old Kwon celebrated his finest hour.

Team Europe are poised to seal yet more Laver Cup glory after producing another dominant display against Team World, though the focus was on Nick Kyrgios following comments about his long-term future.

Europe swept Saturday's four matches in Boston to stand on the cusp of a fourth consecutive Laver Cup triumph – the defending champions lead 11-1 and require just two more points to clinch the title.

Stefanos Tsitsipas blitzed Team World's Kyrgios 6-3 6-4 at TD Garden, where Olympic Games gold medallist Alexander Zverev beat John Isner 7-6 (7-5) 6-7 (6-8) 10-5 before US Open champion Daniil Medvedev made light work of Denis Shapovalov 6-4 6-0.

Team Europe secured their fourth win of the day in the doubles – Tsitsipas and Andrey Rublev teaming up to defeat Isner and Kyrgios 6-7 (8-10) 6-3 10-4.

After Kyrgios' straight-sets loss to Greece's Tsitsipas, the 26-year-old Australian star casted doubt over his tennis future.

"This is my probably my last Laver Cup," former world number 13 Kyrgios – an Australian Open and Wimbledon quarter-finalist – told reporters post-match. "I don't know how much longer I will be in tennis.

"This is my last event of the year. I will get my body right ahead of the Australian Open.

"My mum is not doing too well with her health. I'd like to go back and see her."

"As long as I'm on the court, I will try and give my best, but I'm not going to lie and say that I'm going to plan to play four or five more years on tour," Kyrgios said. "That's just not me."

Playing for the first time since earning his maiden grand slam trophy at the expense of record-chasing Novak Djokovic at Flushing Meadows, world number two Medvedev suffered no letdown against Shapovalov.

"I played unbelievably, especially [in] the second set," Russia's Medvedev said in his on-court interview. "I didn't know what to expect because after the US Open, I didn't play for a week and a half. Came here, practised as much as I could the past three days, so I didn't hit [that] many balls, but was surprisingly feeling well.

"I wanted to show that also today. [The] first [set] was not easy, the ball was not going as fast as I wanted [and] he was playing really good. And then I just couldn't miss a ball anymore. I'm really happy about [that]."