It is nothing new for there to be uncertainty over what to expect for a British and Irish Lions touring party but the class of 2021 are well and truly stepping into the unknown.
Typically all the talk is over selection. Who starts at number 10? What will the make-up of the pack be, who gets the nod as the centre pairing or which wingers will be unleashed in the first Test?
Of course those questions are still to be answered, but when the Lions arrived in Johannesburg on Monday they were not only facing the challenge of trying to secure a starting berth.
A big surge in coronavirus cases has seen South Africa move into a 'level four' lockdown, with travel restrictions, an alcohol ban and an overnight curfew.
As the Lions were preparing to fly out on Sunday, it emerged that Springboks trio Herschel Jantjies, Vincent Koch and Sbu Nkosi had tested positive for COVID-19 - forcing training to be cancelled and the squad going into isolation.
They have since been given the green light to train and are set to face Georgia at Loftus Versfeld Stadium on Friday in their first Test since beating England in the 2019 World Cup final.
A lot of water has gone under the bridge since the drinks flowed as South Africa celebrated lifting the Webb Ellis Cup in Japan and they have a new head coach in Jacques Nienaber.
The world champions have also faced uncertainty, with the possibility of the Lions having home advantage or the series being staged in a neutral country before it was confirmed South Africa will host the tour.
While South Africa know they will not be entering the Lions den, Warren Gatland and his touring party are not certain where they might be heading just under a month before the first Test in Cape Town on July 24.
They are set to face a namesake in the Johannesburg-based Lions side, twice runners-up in Super Rugby, on Saturday as one the first of five matches in Gauteng but it is reported they could make further changes to the schedule.
The COVID situation has led to suggestions the entire three-match Test series could be played in Cape Town, with alternations to the fixtures having already been made last month.
Hostile crowds usually await the Lions, but they are set to face the might of the Springboks behind closed doors without an army of travelling fans to roar them on.
They must also go into battle without inspirational leader Alun Wyn Jones, ruled out due to a dislocated shoulder in the win over Japan at Murrayfield along with Wales team-mate Justin Tipuric.
A strong camaraderie will be needed more than ever, with Conor Murray promoted to skipper the side in the absence of stalwart Jones.
But there will be a lack of nights out as they are restricted to bonding in the bubble.
Gatland's men drew 1-1 with then-world champions New Zealand four years ago and can make it three series without defeat next month - a streak that has not been achieved since 1959.
They have the same head coach and key men who starred against the All Blacks, combined with exciting new faces such as South Africa-born wing Duhan van der Merwe and Louis Rees-Zammit.
Gatland may be unsure what challenges the Lions will face on and off the field before the opening Test but the wily New Zealander knows will know what to expect from a formidable South Africa side.