Simone Inzaghi warned Inter must show more "conviction and malice" after they slumped to a 2-1 Serie A defeat at relegation-threatened Spezia on Friday.

Bartlomiej Dragowski saved an early Lautaro Martinez penalty to set the tone for a miserable night for Nerazzurri, who failed to reduce runaway leaders Napoli's 15-point lead.

Daniel Maldini stunned Inter when the on-loan Milan attacking midfielder put Spezia in front just 10 minutes after being introduced as a half-time substitute.

Romelu Lukaku showed Martinez how it's done by equalising with a spot-kick after 83 minutes, but M'Bala Nzola gave Spezia a first win over Inter when he scored a penalty of his own four minutes later after Denzel Dumfries barged Viktor Kovalenko over.

Inter had 28 shots as they dominated much of the game, but slumped to an eighth Serie A defeat of the season as they prepare to take a 1-0 lead to Porto for a huge Champions League round-of-16 second leg on Tuesday.

Head coach Inzaghi knows the Nerazzurri only have themselves to blame.

He told DAZN: "It hurts, the defeat came in a different way than the others. We put everything on the field, perhaps we needed a little more malice.

"We have a duty to go ahead and I take responsibility for the defeat. We should have been more cynical, we come out stronger from defeats even if there have been more this year."

Six of Inter's eight Serie A defeat this season have come on their travels and Inzaghi says that must be addressed.

"It's a path that doesn't satisfy us away from San Siro, tonight we had to have more conviction and malice," he said.

"I don't believe in luck in football, luck must be sought,"

M'Bala Nzola's late penalty punished wasteful Inter and gave Serie A strugglers Spezia a shock 2-1 victory on Friday.

The Nerazzurri's slim title hopes are surely over after they were beaten by relegation-threatened Spezia for the first time at Stadio Alberto Picco.

Bartlomiej Dragowski saved an early Lautaro Martinez penalty, and that was a sign of things to come as toothless second-placed Inter dominated the majority of the game but lacked a cutting edge.

Daniel Maldini, on loan from Inter's fierce rivals Milan, put Spezia in front just under 10 minutes after coming on as a substitute at half-time, but Romelu Lukaku's late spot-kick looked to have salvaged a point.

Nzola had the final say by slotting home from 12 yards out after Denzel Dumfries barged Viktor Kovalenko over, ensuring Inter remain 15 points behind runaway leaders Napoli.

Jose Mourinho must sit out the Rome derby after an appeal against his Serie A two-match touchline ban was rejected.

The Roma head coach will be a spectator for this Sunday's game against Sassuolo and the tussle with city rivals Lazio seven days later.

His ban was temporarily suspended last week, allowing him to take charge of a game against Juventus, but it now takes immediate effect.

The 60-year-old was sent off for the third time this season just two minutes into the second half of Roma's 2-1 loss at lowly Cremonese on Tuesday, February 28.

Mourinho clashed with fourth official Marco Serra and was sent to the stands, before continuing to argue his case when entering the officials' dressing room after the match.

The Italian Football Association (FIGC) announced a sports court of appeal rejected Roma's challenge to the ban, with Mourinho also fined €10,000 for his behaviour.

The FIGC statement said Mourinho's punishment was imposed "for vehemently and provocatively contesting a refereeing decision, reiterating such behaviour at the time of the expulsion and also for having, at the end of the match, entered, even if authorised, the referee's locker room and addressed to the fourth official seriously offensive expressions and inferences".

Former Chelsea, Inter and Real Madrid boss Mourinho had defended his actions after the game, saying: "I'm emotional but not crazy. For the first time in my career a referee has spoken to me in an unjustifiable way. To have the reaction I had is because something happened."

His Roma side sit fourth in Serie A, ahead of last season's champions Milan on goal difference.

Luciano Spalletti has refuted suggestions Napoli's Scudetto triumph is a mere "formality", ruling out the prospect of the Partenopei focusing on their Champions League campaign.

Napoli suffered just their second defeat of the Serie A season against Lazio last time out, though they still boast a 15-point lead over Inter at the summit ahead of Saturday's meeting with Atalanta.

With Napoli's first league title since the Diego Maradona era appearing to be on the horizon, some have suggested Spalletti could manage his squad ahead of Wednesday's Champions League meeting with Eintracht Frankfurt.

Napoli hold a 2-0 lead at the midway point of that last-16 tie, but Spalletti says his team are not in any position to prioritise future games.

"We always talk about future matches, I've already said many times that it doesn't work like that for us. We face them one at a time and the focus is all on the match against Atalanta," he said.

"We don't have the presumption of being able to manage a championship as if it were a formality or an obstacle to other more important matches.

"The obstacle is only Atalanta for now and they are very strong for many reasons. It is a huge challenge, you have to deserve the final result to bring it home, they are a great team." 

With several potential challengers having dropped away, Spalletti was asked when the title could realistically be secured, but he remains uninterested in such talk.  

"It will be possible when there isn't another team in a position to take as many points as us. Guys, we still have to play many even games," he said.

"We have seen what quality there is in Italy despite what they say in the European comparisons, this says a lot about the difficulties of bringing home the results. 

"Against Lazio we didn't do anything wrong to lose to them, but we found ourselves without any points. 

"I watch the matches, I have them reviewed, and I'm sure there is no need to have a reaction because the performance was there in an important way, but we were facing another team that did important things and took advantage of a moment in their favour."

Napoli are looking to improve on their poor home record against Atalanta, having only won one of their last four league games against Gian Piero Gasperini's side in Naples (D1 L2).

Having suffered a 3-2 defeat in this fixture last season, Napoli could lose consecutive home games against Atalanta for just the second time in Serie A, having previously done so in 1997.

Harry Maguire's future at Manchester United is unclear, having fallen down the pecking order under Erik ten Hag.

The United club captain is contracted until 2025 and his deal includes £200,000 per week wages.

Maguire has only started one of United's last eight Premier League games and did not play in Thursday's Europa League win over Real Betis.

TOP STORY – PSG SET FOR SHOCK MAGUIRE MOVE

Paris Saint-Germain are set for a shock £50million (€56m) move for Manchester United defender Harry Maguire, according to The Sun.

It has been claimed that Maguire is among a list of players that United are willing to sell in the off-season with Newcastle United and West Ham reportedly interested.

According to The Sun's report, PSG tabled a deal for Maguire in January, but time ran out to finalise it and the French champions will move again for him.

ROUND-UP

– The Independent reports Real Madrid are plotting an overhaul to bring in a new generation of young stars, with Manchester City's Erling Haaland top of the list along with Borussia Dortmund's Jude Bellingham.

– The Guardian reports Manchester United will enter the race to sign Chelsea midfielder Mason Mount, with interest also from Liverpool and Newcastle United. Mount and Chelsea are currently in the middle of a contract dispute, potentially making him available, with United viewing him as a cheaper alternative to Bellingham.

–  Barcelona are in the market to sign Manchester City's Portuguese full-back Joao Cancelo if Bayern Munich do not make permanent his loan spell, claims Sport.

– Newcastle are circling to sign Southampton free-kick specialist James Ward-Prowse, according to Football Insider. Newcastle are one of numerous Premier League clubs interested in him.

– Gazzetta dello Sport reports Inter have tabled a two-year contract offer to Edin Dzeko amid interest from West Ham.

– L'Equipe claims PSG are ramping up their bid to sign Manchester City midfielder Bernardo Silva in the off-season.

Romelu Lukaku is "giving excellent signals" following a timely return to form, according to Inter head coach Simone Inzaghi.

The Belgium international has scored just four goals for the Nerazzurri since returning on loan from Chelsea last June.

Two of those have come in his last four appearances - including the winner in the first leg of Inter's Champions League last-16 tie with Porto.

The striker is just one goal away from becoming only the fourth player to score 50 times in Serie A and the Premier League, after Gianfranco Zola, Edin Dzeko and Cristiano Ronaldo.

"We know his value, he came from a problematic period, and now he is giving excellent signals," Inzaghi said of Lukaku during his press conference ahead of Inter's clash with Spezia on Friday. 

"He trains in the best way every day, he scored an important goal against Porto, and we want him to continue to raise the condition."

Second-placed Inter will be expected to cut the gap to runaway leaders Napoli to 12 points with victory over their 17th-placed opponents, who are just three points clear of the relegation zone.

The Nerazzurri saw a six-match unbeaten run ended with defeat at Bologna, but Inzaghi was pleased with his side's response in their routine 2-0 victory over Lecce. 

"We reacted well by having an excellent game against Lecce," he added. "We must continue like this, with this determination, also from tomorrow.

"[It will be] a difficult game, against a team that has a very specific goal for which it is fighting.

"They come from two draws in a row. We will have to interpret the game in the best way, doing simple things."