Orlando Arcia drilled a three-run homer in the 10th inning and the Atlanta Braves won their sixth straight game, 4-1 over the Los Angeles Dodgers in a matchup of the National League’s best teams.

With the initial runner at second, Alex Vesia got the first two outs of the 10th but walked Sean Murphy before Arcia sent a first-pitch fastball over the left-centre field wall for his 17th home run and a 4-1 lead.

Max Muncy had a sacrifice fly in the bottom of the 10th, but Raisel Iglesias struck out Amed Rosario with a runner on for his 28th save.

Major league-leading Atlanta has won the first three games of this much-anticipated series, becoming the first team to reach 90 victories.

The Braves are cruising to their sixth straight NL East title with a 16-game lead over Philadelphia.

Ronald Acuna Jr. opened the scoring in the third inning with his third home run of this series and 32nd of the season.

The Dodgers got the run back in the bottom half when Austin Barnes doubled, moved to third on two walks and scored on a double-play grounder.

Bryce Elder pitched six innings for the Braves and allowed one run and five hits.

Joe Jimenez, A.J. Minter and Michael Tonkin each pitched one hitless inning before Iglesias took over in the 10th.

Reds rally to walk-off Cubs again

Elly De La Cruz delivered a tying single and newcomer Hunter Renfroe beat out a double-play ball as the Cincinnati Reds rallied for their second straight walk-off win, 2-1 over the Chicago Cubs.

Chicago took a 1-0 lead to the ninth after a brilliant eight-inning performance from Javier Assad but Cincinnati scored twice in the ninth to win.

Jake Fraley opened the inning with a double off Mark Leiter Jr. and pinch-runner Harrison Bader stole third. After TJ Friedl walked and Spencer Steer was hit by a pitch, De Le Cruz’s hit tied it.

Nick Martini flied out to keep the bases loaded and Renfroe – claimed off waivers from the Angels earlier this week – hit a grounder to short and barely beat the throw to first, allowing the winning run to score.

Guardians score 2 in 11th to rally past Rays

Steven Kwan had a sacrifice fly and after a key hit by rookie Jose Tena and the Cleveland Guardians rallied for their fourth straight win, 7-6 over the Tampa Bay Rays.

Brandon Lowe gave the Rays a one-run lead in the top of the 11th with a sacrifice fly, but Chris Devenski was unable to protect it in his first appearance with the team.

With one out, Myles Straw stole third and Bo Naylor walked to put runners at the corners. Tena’s single to right tied the game and moved Naylor to third before Kwan’s fly ball to shallow right-centre scored the winning run.

The loss dropped the Rays 2 ½ games behind AL East-leading Baltimore, while the Guardians remained five games in back of Minnesota in the Central.

The Boston Red Sox came from behind on the back of power hitting from Adam Duvall and Rafael Devers to defeat the Detroit Tigers 6-3 away from home on Thursday.

It was the Tigers taking the early lead through a big two-run homer from Jake Rogers in the second inning, and after Enrique Hernandez pulled one run back for the Sox in the third frame with a fielder's choice groundout, legendary Detroit designated hitter Miguel Cabrera came through with an RBI single later in the third to restore a 3-1 advantage.

But the Boston bullpen would shut things down the rest of the way, holding Detroit scoreless for the final six innings.

Red Sox franchise centrepiece Rafael Devers trimmed the margin to one run when he blasted a solo home run in the fourth inning, and he delivered again in the sixth inning with an RBI double to tie the contest at 3-3.

While Devers is the future of the team, there is no Red Sox player hotter than Adam Duvall to start this season.

Through his first five games, the 34-year-old Duvall combined for 10 hits, including three doubles, two home runs and a triple.

He added another home run on Thursday – a three-run bomb later in the sixth inning – to give the Red Sox a winning break, and with it he climbed up to second on the early OPS leaderboard with an on-base plus slugging figure of 1.577. For reference, that is nearly double the best season-long OPS of his career, which was .882 through 41 games in 2019.

It was also the third multi-hit game of the season for 29-year-old AL Rookie of the Year hopeful Masataka Yoshida, with an infield single and a double for the man who signed a five-year, $90million free agent deal out of the Japanese league in the offseason.

Arcia walks it off for Atlanta

Atlanta Braves shortstop Orlando Arcia came up big with a walk-off base hit to defeat the San Diego Padres 7-6 at home.

Arcia, batting last in the Braves' line-up, made some noise early when he got hold of a 400-foot solo home run in the third inning, and he ignited his side's comeback with a double in the eighth inning, later coming around to score as Atlanta turned a 6-4 deficit into a 6-6 tie heading into the last.

The contest looked destined for extra innings until Amed Rosario's two-out double in the bottom of the ninth, with Arcia stepping up next for the game-winning base hit.

It was a great showing for last season's NL Rookie of the Year runner-up Spencer Strider, who followed his nine-strikeout opening performance with another nine strikeouts against the Padres in five innings. 

His 18 strikeouts through two starts is tied for the second-most, trailing only New York Yankees ace Gerrit Cole (19).

Giants pile on 16 runs in Chicago

The San Francisco Giants put up the equal-biggest score of the season so far in a 16-6 drubbing of the Chicago White Sox away from home.

Blake Sabol, Wilmer Flores, Michael Conforto, J.D. Davis and Mike Yastrzemski all hit home runs for the Giants, and while Davis and Conforto both finished with three hits each, Davis led the way with a game-high five RBIs.

All nine Giants starters ended up with at least one hit as they racked up 20 knocks as a team, and the victory clinched their high-scoring three-game series against the White Sox after also taking the opener 12-3.