Italy head coach Roberto Mancini has left out Mario Balotelli from his squad for the upcoming World Cup playoffs, while handing maiden call-ups to Joao Pedro and Luiz Felipe.

The Azzurri failed to top their World Cup qualifying group, which leaves them having to beat North Macedonia in the playoff semi-finals on Thursday to set up a meeting against Turkey or Portugal five days later.

The draw means one of the two previous European Championship winners, Portugal and Italy, will not feature at the 2022 World Cup in Qatar.

Mancini has named a 33-man squad for the upcoming clash against North Macedonia in Palermo, with Balotelli snubbed for the introduction of Cagliari forward Joao Pedro, who was born in Brazil but has an Italian passport.

Lazio defender Luiz Felipe also qualifies under the same criteria and he features in the Italy squad for the first time, while Federico Chiesa and Leonardo Spinazzola miss out through injury.

Moise Kean, Alessio Romagnoli and Davide Calabria were also notable omissions, with Cristiano Biraghi expected to take Spinazzola's full-back spot and Roma's Nicolo Zaniolo filling in for Chiesa.

Matteo Politano, Stefano Sensi and Pierluigi Gollini - who replaces the injured Napoli goalkeeper Alex Meret - all return, with Manuel Locatelli called up despite testing positive for COVID-19 on Thursday.

Locatelli's Juventus colleague Leonardo Bonucci has made the squad even though he suffered a reoccurring problem with his calf in Wednesday's 3-0 Champions League aggregate loss to Villarreal.

Italy squad:

Alessio Cragno (Cagliari), Gianluigi Donnarumma (Paris Saint-Germain), Pierluigi Gollini (Tottenham), Salvatore Sirigu (Genoa); Francesco Acerbi (Lazio), Alessandro Bastoni (Inter), Cristiano Biraghi (Fiorentina), Leonardo Bonucci (Juventus), Giorgio Chiellini (Juventus), Giovanni Di Lorenzo (Napoli), Emerson Palmieri (Lyon), Alessandro Florenzi (Milan), Luiz Felipe (Lazio), Gianluca Mancini (Roma); Nicolo Barella (Inter), Bryan Cristante (Roma), Jorginho (Chelsea), Manuel Locatelli (Juventus), Lorenzo Pellegrini (Roma), Matteo Pessina (Atalanta), Stefano Sensi (Sampdoria), Sandro Tonali (Milan), Marco Verratti (Paris Saint-Germain); Andrea Belotti (Torino), Domenico Berardi (Sassuolo), Ciro Immobile (Lazio), Lorenzo Insigne (Napoli), Joao Pedro (Cagliari), Matteo Politano (Napoli), Giacomo Raspadori (Sassuolo), Gianluca Scamacca (Sassuolo) Mattia Zaccagni (Lazio), Nicolo Zaniolo (Roma).

Fiorentina forward Dusan Vlahovic is winning plenty of admirers.

The 21-year-old Serbian has netted 10 times in 12 appearances at club level this season.

Vlahovic is currently under contract until June 23, although La Viola want him to sign an extension.

TOP STORY – PSG TO ENTER VLAHOVIC RACE

Paris Saint-Germain will enter the race to sign Fiorentina's Dusan Vlahovic, claims Le10Sports.

The Parisians are lining up the Serbian striker as a potential successor to Kylian Mbappe should he exit the club when his contract expires at the end of this season, with Real Madrid circling.

Hot property Vlahovic is being pursued by Juventus, Liverpool and Tottenham.

ROUND-UP

- Unai Emery will not be the first permanent manager in Newcastle United's new era, BBC Sport journalist and Spanish football expert Guillem Balague understands. The Basque coach is set to stay at Villarreal for now, though his job there is under threat amid a poor start to 2021-22.

- The Sun reports Antonio Conte's arrival at Tottenham has seen Harry Kane abandon any plans he had to quit the club. Kane apparently wished to join Manchester City during the most recent transfer window.

- New Spurs boss Conte wants to sign Milan midfielder Franck Kessie, according to Metro. Conte also has Inter defender Stefan de Vrij in his sights, claims Football Insider.

- Milan are in the race to sign talented River Plate star Julian Alvarez in the off-season, according to Gazzetta dello Sport. Fiorentina have also shown interest in 21-year-old Alvarez, who has four caps for Argentina.

- Norwich City are considering a move to replace embattled manager Daniel Farke with former Bournemouth boss Eddie Howe, claims the Daily Mail. The Canaries have only two points from 10 games following their return to the Premier League. Howe has also been linked with the vacant Newcastle job.

- Newcastle want to make Inter's Croatian midfielder Marcelo Brozovic their first major signing in January, says The Sun. Brozovic is out of contract at the end of the season.

- Lazio are looking to convince Luiz Felipe to ink a new deal with the club amid interest from Barcelona, Sevilla and Real Betis, reports CalcioMercato. The Brazilian centre-back's contract expires at the end of this season.

Fiorentina forward Dusan Vlahovic is winning plenty of admirers.

The 21-year-old Serbian has netted 10 times in 12 appearances at club level this season.

Vlahovic is currently under contract until June 23, although La Viola want him to sign an extension.

TOP STORY – PSG TO ENTER VLAHOVIC RACE

Paris Saint-Germain will enter the race to sign Fiorentina's Dusan Vlahovic, claims Le10Sports.

The Parisians are lining up the Serbian striker as a potential successor to Kylian Mbappe should he exit the club when his contract expires at the end of this season, with Real Madrid circling.

Hot property Vlahovic is being pursued by Juventus, Liverpool and Tottenham.

ROUND-UP

- Unai Emery will not be the first permanent manager in Newcastle United's new era, BBC Sport journalist and Spanish football expert Guillem Balague understands. The Basque coach is set to stay at Villarreal for now, though his job there is under threat amid a poor start to 2021-22.

- The Sun reports Antonio Conte's arrival at Tottenham has seen Harry Kane abandon any plans he had to quit the club. Kane apparently wished to join Manchester City during the most recent transfer window.

- New Spurs boss Conte wants to sign Milan midfielder Franck Kessie, according to Metro. Conte also has Inter defender Stefan de Vrij in his sights, claims Football Insider.

- Milan are in the race to sign talented River Plate star Julian Alvarez in the off-season, according to Gazzetta dello Sport. Fiorentina have also shown interest in 21-year-old Alvarez, who has four caps for Argentina.

- Norwich City are considering a move to replace embattled manager Daniel Farke with former Bournemouth boss Eddie Howe, claims the Daily Mail. The Canaries have only two points from 10 games following their return to the Premier League. Howe has also been linked with the vacant Newcastle job.

- Newcastle want to make Inter's Croatian midfielder Marcelo Brozovic their first major signing in January, says The Sun. Brozovic is out of contract at the end of the season.

- Lazio are looking to convince Luiz Felipe to ink a new deal with the club amid interest from Barcelona, Sevilla and Real Betis, reports CalcioMercato. The Brazilian centre-back's contract expires at the end of this season.

Simone Inzaghi was left anguished after his first Serie A defeat as Inter boss came at his former club Lazio, admitting: "We lost our heads."

A 3-1 setback came after a flurry of second-half goals from the home side in Rome, with the defending champions knocked out of their stride late on by a moment of controversy.

With Inter's Federico Dimarco down, apparently injured, Lazio played on and got the 81st-minute goal that put them 2-1 ahead, Felipe Anderson netting from close range after Ciro Immobile's strike was parried by Samir Handanovic.

Inter were furious and both sides had two players booked as bickering on the pitch threatened to spill over. Sergej Milinkovic-Savic sealed the points in stoppage time with a fine header, ending Inter's seven-game unbeaten start to the league campaign.

Inzaghi's new team took the lead against his former charges when Ivan Perisic converted an early penalty, but Lazio had a spot-kick in the 64th minute after Patric's header from a corner was handled by Alessandro Bastoni. Immobile tucked away that chance and the comeback gathered momentum from there.

The result rankled with Inzaghi, who said afterwards: "That was our best recent performance, but when a team like ours is a goal up, we have to manage the game better in terms of our final ball and double our lead."

Quoted on the official Inter website, he added: "Unfortunately, they scored their equaliser from a corner that we shouldn't have conceded. From that point on, the game changed and Lazio got back into the contest.

"The second goal was a bit strange and we lost our heads, which is something we can't allow to happen. It's disappointing. It's a setback that we didn't need in terms of our league position, but we'll take the performance and move on."

Inter sit third in the Serie A standings, behind Napoli and Milan, and their next league clash sees them face Juventus on Sunday of next weekend.

"When you face sides like Lazio, you can't give them a chance to get back into the match," Inzaghi said. "We managed the contest particularly well for an hour, but we then let our opponents back into the game and paid the consequences."

Lazio head coach Maurizio Sarri said Inter should have put the ball out of play themselves when they had an opportunity after Dimarco went to ground.

Sarri was also dismayed to see Luiz Felipe, who had an excellent game in central defence, red-carded after the final whistle.

Luiz Felipe, in celebration mode, jumped on his former Lazio team-mate Joaquin Correa, who left for Inter in August. Correa did not see the funny side and Luiz Felipe was in tears after being dismissed.

"Luiz Felipe told me he was saying goodbye to Correa, they played together for a long time. They didn't want to fight," said Sarri. "It's a big misunderstanding."