There are no more perfect teams in the NFL, just some very good ones.

The Philadelphia Eagles lost their 100 per cent record against the Washington Commanders on Monday, and will look to bounce back in Indianapolis in Week 11.

The New York Jets return from their bye week looking to continue to surprise, though they have a tough trip to the New England Patriots to contend with, while the Minnesota Vikings host the Dallas Cowboys in another enticing clash.

Stats Perform has taken a look at some of the more interesting numbers ahead of these and other big games on Sunday.

Philadelphia Eagles (8-1) @ Indianapolis Colts (4-5-1)

Philadelphia possessed the ball for just 19 minutes and 36 seconds of game time in the loss to the Commanders. It was their lowest time of possession in a game since another loss to Washington in Week 4 of the 2015 season (18:52).

Jalen Hurts rushed for a touchdown last week, giving him 20 in his career. At 24 years and 99 days old, he became the second-youngest quarterback in NFL history to reach 20 rushing touchdowns, trailing only Cam Newton (23 years, 199 days).

Matt Ryan had a 39-yard rush in last week's win over the Las Vegas Raiders, the longest run of his career. It was the longest rushing play by a Colts quarterback since Jim Harbaugh ran for 41 yards in Week 4 of the 1994 season.

With a win, Jeff Saturday would join Jim Caldwell (2009) as the only Colts head coaches to win the first two games of their careers.

New York Jets (6-3) @ New England Patriots (5-4)

The Patriots have won 13 consecutive games against the Jets, winning every meeting since the beginning of the 2016 season. That is tied for the longest active win streak against a single opponent for any team (the Chiefs over the Broncos).

The Jets entered their bye week with a 20-17 win over the Bills in which they had 136 net passing yards. They are 5-0 this season when having 250 or fewer passing yards in a game compared to 1-3 when they have more than 250.

Players aged 23 and younger have gained 2002 yards from scrimmage for the Jets this season, the most in the NFL (next most is the Colts with 1336). That is already the most scrimmage yards for the Jets by players 23 and under since the 1990 season (2452).

Jakobi Meyers leads the Patriots with 457 receiving yards this season, one of five New England players with 200+ receiving yards this season. Only the Green Bay Packers (six) have more players with at least 200 receiving yards in 2022.

Dallas Cowboys (6-3) @ Minnesota Vikings (8-1)

Last week was the Vikings' third win this season after trailing by double digits in the fourth quarter, tying the 1980 Dolphins, 2000 Jets, 2003 Colts and 2011 Lions for the most such wins in a campaign in NFL history.

Justin Jefferson has 814 receiving yards over his last six games, the most in a six-game span in Vikings history and the most by any NFL player over a six-game span in a single season since Antonio Brown recorded 868 in 2015.

With his 81-yard rushing touchdown last week, Dalvin Cook has now had a rush of at least 65 yards in five straight seasons, level with Derrick Henry (2017-21) for the longest streak by any player since the 1970 merger.

Last week's loss to Green Bay snapped the Cowboys' streak of 195 consecutive wins when leading by 14 or more points entering the fourth quarter (including postseason), which had been the longest streak in NFL history.

Elsewhere...

The Buffalo Bills take on the Cleveland Browns having had at least 100 rushing yards and 300 total yards in 16 straight games, including postseason, the third-longest streak in the Super Bowl era behind the Seattle Seahawks (19, 2014-15) and the Vikings (18, 2002-03).

The Detroit Lions will need to stop Saquon Barkley, who had a career-high 35 rushing attempts for 152 yards in the New York Giants' 24-16 win over the Houston Texans last week. His 35 rushes were the most in a game by any NFL running back this season and the most by a Giant since Joe Montgomery had 38 against the Jets in 1999. 

Ahead of facing the Pittsburgh Steelers, Cincinnati Bengals quarterback Joe Burrow has completed 76.8 per cent of his passes over his last four games, the fourth-highest by any QB over a four-game span in a single season in NFL history (minimum 140 attempts, excluding overlapping spans) behind Peyton Manning (78.8) and Philip Rivers in 2013 (78.3), and Sam Bradford in 2016 (77.9).

The Kansas City Chiefs defeated the Los Angeles Chargers in Week 2, 27-24. Since 2018, six of the nine games between the Chiefs and Chargers have been decided by seven points or fewer, tied for the third most of any matchup since then (Bears-Lions and Texans-Colts, seven each).

Elijah Mitchell believes he and Christian McCaffrey could form the best running back tandem in the NFL after he returned in style in the San Francisco 49ers' 22-16 win over the Los Angeles Chargers.

Mitchell, the 49ers' leading rusher as a rookie in 2021, had been sidelined since Week 1 with a knee sprain.

His position as San Francisco's leading back looked to have been taken by McCaffrey last month when the 49ers traded four draft picks to acquire the former All-Pro in a deal with the Carolina Panthers.

However, the pair split carries as the 49ers prevailed in primetime despite an uneven offensive performance. Mitchell carried the ball 18 times for 81 yards and McCaffrey 14 times for 38 yards and a touchdown, the latter also had four catches for 39 yards.

The 49ers finished with 157 yards on the ground but at an average of just 3.8 yards per carry, however, Mitchell is confident he and McCaffrey can take their rushing attack to great heights.

"At the end of the day, it helps both of us and like I said, year six and he's an unbelievable back," Mitchell said of McCaffrey's arrival. "I get to learn from him so I'm excited for it.

"We could be the best duo of backs in the league, in my opinion."

The 49ers' victory moved them to 5-4, trailing the Seattle Seahawks (6-4) by just half a game in the race for the NFC West title.

That record is identical to that of the Chargers, who could not overcome critical injuries on the offensive side of the ball to the likes of Keenan Allen and Mike Williams.

San Francisco's vaunted defense dominated and shut out the Chargers in the second half, and running back Austin Ekeler refused to blame the Chargers' injuries for their struggles.

"We got some of our guys who are down," Ekeler said. "I get it. That doesn’t matter. . . . No one really created today.

"We need more playmaking. We didn't have that in the second half. We can't just go out there and play hard. That doesn't win in the NFL."

The San Francisco 49ers had a dominant second half to end the Los Angeles Chargers' dominance over them with a 22-16 victory at Levi's Stadium on Sunday.

The Niners' running game came to the fore in the second half, taking the lead for the first time with 7:54 remaining in the fourth quarter after Christian McCaffrey's touchdown.

San Francisco went 12-0 in the second half, turning around a 16-10 half-time deficit, ending the Chargers' five-game streak against them. The win means San Francisco claimed back-to-back victories to improve to 5-4, while the Chargers dip to 5-4 having lost two of their past three games.

The Niners enjoyed more possession, rushing for 157 yards compared to the Chargers' 51, with Elijah Mitchell (89 yards on 18 carries) and Deebo Samuel (27 yards on four carries) contributing well on their returns from injury.

Niners quarterback Jimmy Garoppolo completed 15 of 23 passes for 197 yards with no touchdowns or interceptions, although he ran in a TD late in the first half.

Garoppolo linked up with Brandon Aiyuk, who had six receptions for 84 yards, on a 24-yard pass leading to McCaffrey's decisive rushing two-yard TD.

The Chargers scored on the opening drive of the game when QB Justin Herbert pinpointed DeAndre Carter on a 32-yard deep left pass.

In the final two minutes, a one-handed Josh Palmer could not reel in a desperate fourth-down pass from Herbert, who finished the game on 21-of-35 passing for 196 yards with one TD and one interception, before Robbie Gould made it a six-point game with a 20-yard field goal.

The San Francisco 49ers are getting healthy at the right time as they bid to kick-start a second-half surge towards the postseason and get a rare win over the Los Angeles Chargers on Sunday.

San Francisco had their bye in Week 9, having got to 4-4 in emphatic fashion a week earlier, routing the Los Angeles Rams 31-14 at SoFi Stadium.

They return home to Levi's Stadium to face the Chargers in primetime and, while they have beaten the Rams eight times in a row in the regular season, they have not had such fortune against the other Los Angeles team in the NFL.

Indeed, the Chargers are looking to win their sixth straight game against the 49ers, which would make them the first team to do so since the Seattle Seahawks (who nine games from 2014 to 2018).

However, the two teams have not met since Los Angeles' home win in Week 4 of the 2018 season.

The 49ers, who have once again battled the injury bug in a recurring theme of head coach Kyle Shanahan's tenure, are set to get eight players back from absences.

Versatile star wide receiver Deebo Samuel (hamstring), Jauan Jennings (hamstring), fullback Kyle Juszczyk (finger) and linebacker Dre Greenlaw (calf) are all set to return after missing the win over the Rams.

Running back Elijah Mitchell, linebacker Azeez Al-Shaair, backup tackle Colton McKivitz and defensive end Jordan Willis will also make their comebacks from injuries that saw them placed on the injured reserve list.

Mitchell has not played since injuring his knee in Week 1, and it is his and Samuel's infusion back into the lineup that will be most intriguing to watch from an offensive standpoint for San Francisco.

Neither Samuel nor Mitchell has had the chance to play with 49ers running back Christian McCaffrey, whom San Francisco acquired in a blockbuster trade with the Carolina Panthers last month.

In his second game against the Rams, McCaffrey threw for, rushed for and caught a touchdown. He was the first player to do so in the same game since the Chargers' LaDainian Tomlinson completed the feat in Week 6 of the 2005 season and only the fourth since the 1970 merger.

Adding Samuel, whose ability to excel as a receiver and a running back propelled the Niners to the NFC Championship Game last season, and 2021 leading rusher Mitchell into the mix alongside another dual running and receiving threat in McCaffrey opens an array of options for Shanahan, especially against a Charger run defense allowing the most yards play (5.7) on the ground in the NFL.

In contrast to the 49ers' improving injury report, the Chargers will again be without top wide receivers Keenan Allen and Mike Williams, while right tackle Trey Pipkins is out with a knee injury. Practice squad lineman Foster Sarell could get the nod in his stead ahead of much-maligned backup Storm Norton.

Despite losing left tackle Rashawn Slater to a torn ACL earlier in the season, the Chargers' offensive line has held up well. Quarterback Justin Herbert was not sacked in the win over the Atlanta Falcons in Week 9, and the Chargers have allowed the fewest sacks in the league this season (10). They have not given up 10 or fewer sacks through eight games since the 2008 season (also 10).

That could change against a fearsome 49ers defensive front. The Niners are third in the NFL with a sack rate of 8.9 per cent, though they are once again missing their best interior pass rusher, Arik Armstead, with a foot injury.

The lack of receiving weapons and injuries up front would appear to put Herbert and the 5-3 Chargers in a tough spot. However, the 49ers will be wary of Herbert's ability to overcome adversity, as he has continued to thrive even as the Chargers have failed to deliver since he entered the league in 2020.

Through 40 career starts, Herbert has accounted for 90 touchdowns (82 passing, 8 rushing). Only Patrick Mahomes (107), Dan Marino (95) and Kurt Warner (91) accounted for more scores in their first 40 starts.

Los Angeles Chargers head coach Brandon Staley tried to explain to reporters on Friday why he decided to release former first-round draft pick Jerry Tillery just weeks after rejecting trade offers for him.

Tillery, 26, was taken with the 28th overall pick in the 2019 NFL Draft, tallying 97 tackles, 9.5 sacks and two forced fumbles across his first three seasons.

However, his fifth-year option was declined by the franchise, and he has failed to start a game this campaign.

According to ESPN, the Chargers received "multiple" offers for Tillery leading up to the November 1 trade deadline, but chose to decline in the hope that he could provide depth down the home stretch.

That decision ended up backfiring, as a breakdown in the relationship between player and team led to the Chargers releasing Tillery on Thursday for no compensation.

Speaking to the media on Friday to explain the decision, Staley implied Tillery was not going to accept the limited role the team was asking him to remain in.

"[We had] competing visions for the role moving forward, and it just became clear that it wasn't going to be a fit anymore," he said.

"Where we're headed as a team wasn't going to be compatible with Jerry and where he's trying to go.

"We felt we were going to give [Breiden Fehoko] and [Joe Gaziano] a chance to compete and where we're at, trying to do with our team, our defensive line, our defense, our whole team, trying to create competition and have guys earn their roles.

"That's what we want to be here, that's what we want to do. When those things didn't line up, we had to make a change."

We are somehow already at Week 10 in the NFL season, all wondering where the time actually does go.

Two of the shining lights of the campaign face off in Buffalo as the Bills host the Minnesota Vikings.

History will be made in Munich as the Tampa Bay Buccaneers face the Seattle Seahawks in the first-ever regular season NFL game played in Germany, while the San Francisco 49ers will look to continue their return to winning ways against the Los Angeles Chargers.

Stats Perform takes a closer look at the numbers behind some of Sunday's NFL clashes.

Minnesota Vikings (7-1) @ Buffalo Bills (6-2)

The Vikings have played eight games at Highmark Stadium and have held the Bills to 23 points or fewer in each one, which is the longest streak of allowing 23 points or fewer by a visiting team in the stadium's history.

Minnesota have won six straight games, all by eight points or fewer, tied for the second-longest streak of one-possession wins in NFL history, behind a seven-game streak by the Kansas City Chiefs in 2020.

T.J. Hockenson boasted nine catches on his Vikings debut last week, tying the Bills' Keith McKeller (October 18, 1987) for the most receptions by a tight end on debut with a team in the Super Bowl era.

The Bills have allowed 21 points or fewer in 12 straight regular-season games, the longest streak in franchise history and the second longest by any NFL team over the last 15 seasons (Baltimore Ravens, 13 straight from 2019-20).

Buffalo are allowing just 4.6 points per game in the second half this year. No NFL team has allowed fewer than 5.0 points per game in the second half over a full season since the Carolina Panthers in 1996 (3.5).

Seattle Seahawks (6-3) @ Tampa Bay Buccaneers (4-5)

It should be a great experience in Bavaria, but the Bucs are 0-3 in games played outside the United States (all in London), having been outscored 96-51 in those games. The Seahawks, meanwhile, are 2-0 outside the U.S. (one in Toronto, one in London), outscoring their opponents, 77-20.

Pete Carroll is in his 17th season as an NFL head coach and has had at least six wins in each campaign. The only other coach to have six or more wins in each of his first 17 seasons was Don Shula, who did so in all 33 seasons of his career.

Kenneth Walker III is the first NFL rookie to rush for a touchdown and have his team win in each of his first four career starts since Robert Edwards for the New England Patriots in 1998.

Tom Brady has thrown at least 40 passes with no interceptions in seven consecutive starts. No other QB in NFL history has done that in more than four straight starts.

The Bucs have rushed for 75 or fewer yards in eight straight games, the second-longest streak in the Super Bowl wera behind a nine-game streak by the Cardinals from 1991-92.

Los Angeles Chargers (5-3) @ San Francisco 49ers (4-4)

The Chargers are looking to win their sixth-straight game against the 49ers, which would make them the first team to do so since the Seahawks (nine games from 2014 to 2018).

Justin Herbert was not sacked in the Chargers' recent win against the Atlanta Falcons. The Chargers have allowed the fewest sacks in the league this season (10), and have not allowed 10 or fewer sacks through eight games since the 2008 season (also 10).

Through 40 career starts, Herbert has played a part in 90 touchdowns (82 passing, eight rushing). Only Patrick Mahomes (107), Dan Marino (95) and Kurt Warner (91) accounted for more scores in their first 40 starts.

San Francisco's last five games have all been decided by at least 14 points (3-2 record). They have not had six consecutive such games since an eight-game streak in 1999.

Christian McCaffrey threw for, rushed for and caught a touchdown in San Francisco's win over the Rams. He was the first player to do so since the Chargers' LaDainian Tomlinson completed the feat in Week 6 of the 2005 season.

Elsewhere...

The Jacksonville Jaguars (3-6) will need a plan to deal with Chiefs (6-2) QB Mahomes, who attempted 68 passes (completing 43) in last week's win over the Tennessee Titans, both of which set single-game team records. The only player to attempt more passes in a win in the NFL since 1950 was Drew Bledsoe with 70 in Week 11 of the 1994 season.

Former Chief Tyreek Hill has 1104 receiving yards this season for the Miami Dolphins (6-3), the most by any player through his team's first nine games in the Super Bowl era. Prior to this year, there had only been 11 times a Dolphins receiver recorded 1100 yards in an entire season, and Hill will look to add to those against the Cleveland Browns (3-5).

Last week was Cooper Kupp's 20th career game with at least 100 receiving yards and a touchdown, the most in the NFL since he entered the league in 2017. The only other players with more than 15 such games in that span are Davante Adams (19) and Hill (18), and the Los Angeles Rams (3-5) will need their star to step up again against the Arizona Cardinals (3-6).

Aaron Rodgers' passer rating is at 89.0 this season after posting 111.9 in 2021. The decrease of 22.9 is the largest by a Green Bay Packers quarterback (min. five games played) since Bart Starr from 1966 to 1967 (105.0 to 64.4). With a record of 3-6, the Packers will hope he can improve that against the Dallas Cowboys (6-2).

While the rest of his teammates should come back from a bye week refreshed, Los Angeles Chargers wide receiver Keenan Allen is feeling anything but. 

Allen, who has only suited up for two of his team's seven games this season, experienced a setback with his injured left hamstring during a training session and may not be healthy enough to play on Sunday against the Atlanta Falcons. 

''I don't think it was a re-strain or anything. Just some more scar tissue is trying to break off,'' Allen said. ''Whenever it's ready to heal, just let it do its own thing.'' 

Allen injured his hamstring in the season opener and missed the next five games before returning for a Week 7 matchup against the Seattle Seahawks. He played 23 first-half snaps against the Seahawks and finished with two catches for 11 yards. 

''I felt great. It wasn't like training camp,'' said Allen on how he felt during the game. ''I definitely felt ready to play.'' 

After missing practice on Monday and Wednesday, Allen is questionable for Sunday. He wouldn’t put a timetable on his return but said that he did not want to come back until there was absolute certainty in his health. 

"I definitely don’t want to do the halfway thing again," he said. "Just want to come back 100 percent and not be worried about it."

Allen’s absence Sunday would loom even larger because the Chargers could be without receivers Mike Williams (ankle) and Joshua Palmer (concussion protocol).  

With all the injuries to receivers, Austin Ekeler leads NFL running backs with 53 receptions. It is only the third time a running back has at least 50 catches through his team's first seven games.

The Los Angeles Chargers lost two strong players at important positions in Sunday's disappointing 37-23 loss to the Seattle Seahawks, with All-Pro cornerback J.C. Jackson and starting wide receiver Mike Williams both suffering injuries.

While still not great, the news is better for Williams, who was diagnosed with a high-ankle sprain that will keep him out of action for "a matter of weeks, not days", according to Chargers head coach Brandon Staley.

Unfortunately for Jackson – who had not missed a game for the past three seasons – his campaign is over after rupturing his patella tendon. The Chargers signed Jackson to a five-year, $82.5million deal in free agency after he played four seasons with the New England Patriots and led the NFL over that span with a league-high 25 interceptions.

It adds to a troubling injured list for the Chargers, who are already without stars Rashawn Slater at left tackle and pass-rusher Joey Bosa after the pair were placed on the injured reserve at the end of Week 3, and five-time Pro Bowl receiver Keenan Allen was only able to return to the field in Week 7 in a limited fashion.

Speaking to the media on Monday, Staley said the Chargers would weigh up whether they need to make any significant moves before the rapidly approaching trade deadline on November 1.

"I think in the next couple days, we'll be able to assess our team a lot better," he said. "We'll take the next couple days and... make those types of discussions happen, and we'll see.

"We're always going to look for avenues to enhance our team and make it better."

On Bosa, Staley said he is "making progress" without providing any timetable for his return, while he also added that he limited Allen's work in his first game back from injury due to a visible lack of "burst".

"I just didn't feel like he could really burst the way that he wanted to and didn't want to risk anything happening," he said. "So no setback yesterday, but just didn't want to push it."

Geno Smith believes he can play even better after leading the Seattle Seahawks to a victory that lifted them to the top of the NFC West.

Unfancied and seen as a rebuilding team after the decision to trade nine-time Pro Bowl quarterback Russell Wilson to the Denver Broncos in the offseason, the Seahawks are now 4-3 after the latest success authored by Smith.

The former first-round pick of the New York Jets is penning a remarkable comeback story having beaten Drew Lock to the starting quarterback job in Seattle. 

Smith went 8-8 as a rookie with the Jets in 2013 but saw his career fall apart from there as poor play, a fractious relationship with former coach Rex Ryan and a now infamous locker room fight in 2015 derailed his hopes of being the long-term answer in New York.

He spent seasons with the New York Giants and Los Angeles Chargers before eventually landing in Seattle as Wilson's backup in 2019, playing three games in relief of the injured starter last season.

The Seahawks won only one of those starts, and there was little to suggest he could lead them to playoff contention in 2022. However, they have now won three of their last four games, with Smith leading the NFL with a completion percentage of 73.5.

Sunday saw him complete 20 of his 27 passes for 210 yards, two touchdowns and one interception as the Seahawks saw off the Chargers 37-23.

Asked by Peter King for his Football Morning in America column what surprises him most about his and Seattle's success, Smith replied: "Nothing. Nothing has surprised me. In fact, I know I can play a lot better.

"In my rookie year playing with the Jets, we went 8-8 and missed the playoffs by one game. The reality is it's hard to win the NFL with a young quarterback. That's just the reality of the NFL.

"So much goes on that you have to know in order to be successful. Quarterbacking is a skill more than just a talent. I'm just happy I've just continued to develop.

"I know I might've struggled out the gate in pro football. That's just the reality of the NFL. Sometimes they give up on you fast.

"The numbers at the beginning of my career are kind of skewed, if you ask me. If you look at Peyton Manning, if you just judge his rookie season, you'd never think Peyton Manning would've become what he became. Steve Young, too. Troy Aikman. The list goes on and on and on.

"[You have] just got to have patience with young quarterbacks. You have got to find the right young quarterbacks with the right mentality who are going to continue to work and have a great attitude about the game and the struggle.

"Over the years, not playing was heartbreaking. I’m so competitive, and I love playing so much that I really wanted to be out there every single game. But what's that cliche? 'What doesn't kill you makes you stronger'?

"I know I’m better for all those years. Coming into this year, I wasn't sure what would happen [after the trade of Wilson to Denver].

"When [Seahawks coach] Pete Carroll hit me up and was like, 'Hey I'm giving you opportunity to compete for the job,' I mean, that’s all you have to say to me. That was awesome. He's shown faith in me. That's just what I need.

"You ask me: what am I focused on during the week? Playing hard, doing what I'm coached to do. It's that simple. I don't think about failure.

"My thought process is I need to run on the field with my linemen and play just as hard as they're playing and do exactly what I'm coached to do and then let my talent take over after that. It's that simple in my mind.

"Our success so far starts with the trust and belief of our head coach. Not many coaches would start two rookies on the offensive line, a rookie running back, two rookie cornerbacks.

"Not many coaches would be comfortable starting a quarterback who hasn't played in many years. But Pete does it because he knows what he's looking at. He's played young guys before, lots of times. He's taken chances on players, lots of time. He knows how to coach ball. You can see that this year.

"I think we're built to last for this season and many seasons. But ultimately, it comes down to what we do, not what we say. It's about the work we put in. It's about the consistency. And our preparation and consistency and our togetherness. That's all that matters.

"As long as we continue to build together, the sky's the limit. It takes work. It takes hard work. We have got to embrace that part of it."

The Kansas City Chiefs are the highest scoring team in the NFL through Week 7 after a convincing 44-23 road win against the San Francisco 49ers on Sunday.

San Francisco were in the headlines this week after pulling the trigger on a big trade for superstar running back Christian McCaffrey, but it was Chiefs quarterback Patrick Mahomes controlling the contest.

Mahomes threw an interception on the Chiefs' first drive, but turned things around quickly and ended up completing 25 of his 34 passes for 423 yards and three touchdowns.

He tossed second-half touchdown passes to Justin Watson and JuJu Smith-Schuster, and his first touchdown pass to Mecole Hardman was the beginning of a memorable day for the speedy receiver.

After getting on the end of an eight-yard score from Mahomes in the first quarter, Hardman then took a jet-sweep 25 yards down the sideline in the second quarter for the first rushing touchdown of his career. 

Not done yet, Hardman added his second rushing touchdown and third overall score for the game with a three-yard run in the fourth period. He finished with two carries for 28 yards and two rushing TDs, with four catches for 32 yards and a receiving TD.

For the 49ers, Jimmy Garropolo was not to blame for the loss as he finished 25-of-37 for 303 yards, two touchdowns and an interception – with touchdown passes to George Kittle and Ray-Ray McCloud III.

McCaffrey carried the ball eight times for 38 yards, and caught both of his targets for 24 yards through the air.

Seahawks move above .500 with upset in Los Angeles

The Seattle Seahawks rode a spectacular performance from rookie running back Kenneth Walker III to a 37-23 upset win on the road against the Los Angeles Chargers.

Walker rushed 23 times for 168 yards and two touchdowns, capped by a 74-yard rushing touchdown in the fourth quarter to put the game to bed.

Seahawks quarterback Geno Smith was solid, completing 20-of-27 passes for 210 yards and a pair of touchdown passes to Marquise Goodwin as he assumed a major role following a knee injury to key wide receiver D.K. Metcalf.

Chargers star Austin Ekeler remains the top running back in fantasy football, rushing for 31 yards and a touchdown, as well as catching all 12 of his targets for 96 yards and a second score.

Christian McCaffrey is expected to make his debut for the San Francisco 49ers against the Kansas City Chiefs.

Former All-Pro running back McCaffrey was traded to the 49ers from the Carolina Panthers on Thursday for second, third and fourth-round picks in 2023 and a fifth-rounder in 2024.

The tight turnaround initially made it look unlikely McCaffrey would be overly involved in a rematch of Super Bowl LIV from the 2019 season.

However, according to ESPN's Adam Schefter, McCaffrey will play and the 49ers will have a package of plays ready for him.

The Chiefs will have a new lead runner in their backfield, with rookie Isaiah Pacheco set to get the bulk of the carries over 2020 first-round pick Clyde Edwards-Helaire.

Kansas City's closest rivals in the AFC West, the 4-2 Los Angeles Chargers, face NFC West opponents themselves in the form of the Seattle Seahawks.

They had hoped to have wide receiver Keenan Allen back from a hamstring injury that has kept him out since Week 1, but his status was still up in the air heading into Sunday.

Star Seahawks wideout Tyler Lockett is set to play having been listed as questionable with a hamstring injury of his own.

The Baltimore Ravens, another prospective AFC contender, have been boosted with tight end Mark Andrews (ankle) and Rashod Bateman (knee) both active for their meeting with the Cleveland Browns. 

The Dallas Cowboys will not have to defend D'Andre Swift in Dak Prescott's return to action. Detroit Lions running back Swift is once again inactive because of ankle and shoulder injuries.

Detroit's division rivals the Green Bay Packers are looking to end a two-game losing run and get their offense back on track against the Washington Commanders.

Yet they will be without oft-injured left tackle David Bakhtiari because of a flare-up in his knee. The Packers have remodelled a struggling offensive line, shifting Elgton Jenkins from right tackle to left guard. Yosh Nijman takes over at right tackle, with rookie Zac Tom filling in for Bakhtiari.

Wide receiver Sammy Watkins will return from a knee injury as Aaron Rodgers desperately searches for targets he can trust.

Dustin Hopkins lined up the field goal that would settle the Los Angeles Chargers' clash with the Denver Broncos and thought to himself: what's the worst that could happen?

Already carrying a hamstring injury, Hopkins figured he may as well take a full-blooded kick for glory and hold nothing back.

"In my mind, it was already at a point where it was a, 'Well, screw it' moment," said Hopkins. "Pretty much, if it's already feeling this bad at this point, let's just give it a ride."

The overtime heroics from Hopkins, who kicked four field goals in all, secured a 19-16 win for the Chargers, with quarterback Justin Herbert saluting the kicker.

"We have so much respect for him. We know that he is hurting," said Herbert. "He's tough. That's all you can say about him. For him to go out there and play and put up with some pain like that, it's great to see from him."

Chargers head coach Brandon Staley saw his team nullify the threat of Russell Wilson after the first quarter, in which the Broncos quarterback completed all 10 of his passes, including a 39-yard touchdown to rookie tight end Greg Dulcich.

The Chargers rallied from 10-0 adrift but could only manage one touchdown that came at the start of the second quarter, with a 15-play drive capped off by a six-yard Austin Ekeler touchdown dash.

They had to grind it out, and Staley said: "This is a complete team win. It was a tough, rugged game. They have an outstanding defense over there. It was tough sledding in every way for all four quarters and overtime. It was just a tough and rugged game. It took everybody in Powder Blue to win it."

He added: "The fact that we're able to show our resilience in all three phases, and then be able to finish that game on our home field in front of our fans, I'm really proud of our group today."

Losses to the Chiefs and the Jaguars came as early season setbacks for the Chargers, but Herbert has been encouraged by the wins that have followed against the Texans, Browns and now the Broncos.

"I thought 4-2 has been a big step up for us," he said, "especially where we were at with 1-2.

"For us to answer back and to win three games in a row like that, I think it says a lot about our team, our defense, our special teams, because they have stepped up big time. It's been awesome to see from them."

Herbert completed 37 of his 57 passes for 238 yards and one interception. This made him the only quarterback in the Super Bowl era to throw as many as 57 passes in a game with no TDs but still win, Opta said.

Denver Broncos quarterback Russell Wilson confirmed he injured his hamstring in his side's 19-16 overtime loss to the Los Angeles Chargers on Monday night.

Wilson began the game brightly, finishing the first quarter with a perfect 10 completions from 10 attempts including a touchdown to rookie tight end Greg Dulcich to build a 10-0 lead at quarter-time.

Things broke down for the Broncos' offense after that, with Wilson going on to complete just five-of-18 passes the rest of the way as their only points in the last three quarters came from a pair of Brandon McManus field goals.

After the game, Broncos head coach Nathaniel Hackett opened up his press conference by listing Wilson among the injuries for the game, saying he hurt his hamstring and not expanding any further.

When questioned about it in his own interview, Wilson confirmed he did indeed have to nurse the injury through the latter stages of the contest after feeling it pull in the fourth quarter..

"Yeah, I got my hammy," he said. "I was kind of scrambling and moving around on one, and had to throw it away. It got me pretty good in the fourth quarter, but I just tried to play through it and all that.

"I felt good moving around, running around, throwing it and everything else – especially early on – and then that happened. 

"So that was kind of a little unfortunate, but, you know, [we were still] trying to find a way to win the game."

Wilson entered the game with a nagging shoulder injury, and he said his "shoulder did good", but that "the only thing that matters is us winning".

If Wilson did indeed strain his hamstring, even a minor injury will likely mean at least one game on the sideline, while a medium-severity strain would force him to miss two or three games at a minimum.

The loss relegates the Broncos to a 2-4 record through Week 6, with a home fixture against the New York Jets scheduled for this Sunday.

The Los Angeles Chargers needed a Dustin Hopkins field goal in overtime to defeat the Denver Broncos 19-16 on Monday night.

Despite the final result, it was a bright start for Broncos quarterback Russell Wilson, who completed all 10 of his passes in the first quarter, including a 39-yard touchdown to rookie tight end Greg Dulcich to lead 10-0 at quarter-time.

Whatever adjustments the Chargers made during the first break seemed to have an immediate effect, with Wilson only completing five of his next 18 passes as the Broncos could only muster a pair of field goals the rest of the way while committing 151 yards of penalties – a Monday Night Football record since penalty yardage began being tracked in 2000. 

The Chargers also only had one touchdown in the game, opening the second quarter with a 15-play drive capped off by a six-yard Austin Ekeler touchdown run.

A field goal from either side in the final minute of the half had the Broncos up 13-10, and they continued to trade field goals the rest of regulation, with Hopkins nailing his third of the night to tie the game at 16-16 with four minutes remaining.

Neither team was able to mount a game-winning drive late in the fourth quarter, and things looked headed for the tie after overtime started with four consecutive three-and-out punts. But the fourth was unsuccessfully fielded by Broncos punt returner Montrell Washington after a blocking teammate was pushed into him, resulting in a fumble and turnover.

After again failing to get a first down, the Chargers called on Hopkins to end it, and while playing with an injury, he sealed the win with his fourth field goal from four attempts.

Chargers quarterback Justin Herbert completed 37 of his 57 passes for 238 yards and one interception, while Wilson finished 15-of-28 for 188 yards and one touchdown. Ekeler was the top skill-position player, rushing 14 times for 36 yards and a touchdown while catching 10 of 16 targets for 47 receiving yards.

The Los Angeles Chargers survived a late scare to defeat the Cleveland Browns 30-28 on Sunday afternoon thanks to a massive performance from running back Austin Ekeler.

Ekeler finished with two of the Chargers' three touchdowns, rushing for 173 yards and a score from 16 carries, and adding 26 yards and a touchdown from four catches.

Both times Ekeler scored he put the Chargers back into the lead in a rollercoaster of a game, where the Browns jumped out to a 14-0 lead in the first quarter through touchdowns to focal points Amari Cooper and Nick Chubb.

Chubb's second rushing touchdown gave the Browns a 17-14 lead at half-time, and they were up 28-27 going into the fourth quarter after Kareem Hunt converted a goal-line carry for a touchdown of his own.

Taylor Bertolet's field goal put the Chargers back in front with nine minutes to play, finishing three-for-three with his kicks for the day, and the game looked to be sealed when Browns quarterback Jacoby Brissett threw an interception with under three minutes on the clock.

Needing a couple of first downs to put on the finishing touches, the Chargers were presented with a fourth-and-one at their own 46-yard line, and instead of punting and playing it safe, they went for it and failed.

A short completion gave the Browns a 54-yard field goal opportunity to win the game in the final seconds, but it drifted wide right, with kicker Cade York missing both of his attempts for the game.

Chargers quarterback Justin Herbert completed 22 of his 34 passes for 228 yards and a touchdown with no turnovers, with his top receiver Mike Williams catching 10 for 134 yards.

Chubb was the offensive star for the Browns, carrying 17 times for 134 yards and two touchdowns.

Bills blow away the Steelers

The Buffalo Bills took their foot off the gas in the second half to coast to a dominant 38-3 victory against the Pittsburgh Steelers.

Wide receiver Gabriel Davis was the star of the show along with quarterback Josh Allen, combining on a 98-yard passing touchdown just 64 seconds into the game. It was the longest touchdown in the NFL this season.

They were not finished there, linking up again to begin the second quarter with a 62-yard touchdown.

Allen added two more touchdown passes in the first half – one to Stefon Diggs and one to Khalil Shakir – to open up a 31-3 lead at the long break, and from there they were never tested.

Another Dolphins quarterback leaves with concussion

Making his first start of the season after Tua Tagovailoa was sidelined with his concussion last week, Miami Dolphins quarterback Teddy Bridgewater was pulled after the first play in a 40-17 loss to the New York Jets.

Bridgewater was evaluated for a concussion and could not return, handing rookie Skylar Thompson his first snaps as a professional. 

Neither team threw for a touchdown in the game, with the Jets rushing for five scores as exciting rookie Breece Hall finished with 18 carries for 97 yards and a touchdown, adding two catches for 100 yards, and goal-line back Michael Carter pushed his way in for two touchdowns.

Adding to the great day for Jets fans was the fourth overall pick from this year's NFL Draft, cornerback Sauce Gardner, recording his first career interception.