Javier 'Chicharito' Hernandez started the MLS season with a bang, scoring twice as LA Galaxy spoiled Phil Neville's Inter Miami debut in a 3-2 victory.

Former Manchester United and Real Madrid striker Chicharito endured a difficult and injury-plagued 2020 season, Mexico's all-time leading goalscorer netting just twice after joining the Galaxy.

But Chicharito kicked off his redemption season in style – his two-goal second half sinking David Beckham's Inter Miami in Sunday's season opener.

"I'm holding [back] my tears. I suffered the loss of my grandfather, I would love him to keep watching [me] scoring goals," Chicharito said. "I'm very touched because, like I told you, last year was very difficult.

"I miss him so much and these goals are for him, my kids, my whole family, my friends, everyone. I maintain patience, I keep grinding and thankfully things are coming around and hopefully, like I say, I just want to be a part of an unbelievable season and lift the trophy."

Trailing to Robbie Robinson's opening goal in first-half stoppage time, Chicharito equalised just past the hour mark in front of a sell-out crowd in Miami.

Former Juventus and Real Madrid striker Gonzalo Higuain restored Inter Miami's lead in the 68th minute – just his second goal for the club since arriving in the United States.

It had ex-United utility and former England women's boss Neville dreaming of a dream start in Miami, where he replaced Diego Alonso as head coach ahead of the 2021 season.

But Chicharito levelled proceedings again with a trademark header 17 minutes from the end before Sacha Kljestan put the Galaxy in front in the 81st minute.

Elsewhere, reigning champions Columbus Crew drew 0-0 against Supporters' Shield holders Philadelphia Union, while Vancouver Whitecaps edged Portland Timbers 1-0.

LA Galaxy have appointed former Toronto boss Greg Vanney as their head coach.

Vanney, who resigned from his position at Toronto in December, takes over after a difficult 2020 season for Galaxy.

The former Galaxy defender said he was looking forward to the opportunity as he replaces Guillermo Barros Schelotto.

"I am extremely excited about the opportunity to coach the LA Galaxy," Vanney said.

"The LA Galaxy are an iconic club with a rich history in Los Angeles, MLS and North American soccer over the last 25 years.

"I am committed to working tirelessly for this club, our fans and Los Angeles to win a championship. I look forward to this new challenge in my career and am eager to get started."

Galaxy have missed the playoffs in three of the previous four seasons, winning just six games in 2020.

Vanney led Toronto to a treble in 2017, winning the MLS Cup, Supporters' Shield and Canadian Championship.

"Greg is a part of the history of the LA Galaxy and we are confident that he is the right person to lead our team moving forward," Galaxy general manager Dennis te Kloese said.

"He has deep knowledge of this club and Major League Soccer as a player and a coach and has proven to be a consistent winner with a championship pedigree. His accolades as Toronto FC's manager are evidence of his ability to create and sustain success in our league.

"We look forward to working with Greg to continue to build a team that will compete for trophies."