Marc Marquez crashed out on the second lap as championship leader Fabio Quartararo claimed a third MotoGP victory of the season at the Italian Grand Prix on Sunday. 

In a race overshadowed by the death of Moto3 rider Jason Dupasquier after a crash in qualifying on Saturday, Quartararo became the first rider to win in Mugello after starting from pole position since 2014. 

Meanwhile, Marquez's hopes of securing a strong result in his fourth race since returning from a broken arm were ended at turn three on the second lap when he made contact with Brad Binder.

Quartararo started from his fourth consecutive pole, but he was usurped by Francesco Bagnaia almost immediately. 

Ducati rider Bagnaia fell from the front on just the second lap, though, handing the advantage back to Quartararo, who fought off the threat of fellow Frenchman Johann Zarco to seal a third win in six races.

This latest victory extended his lead at the head of the standings to 24 points over Zarco, who was leapfrogged by Miguel Oliveria into second with eight laps remaining, with Joan Mir pushing him off the podium soon after. 

Alex Rins pushed Zarco further down the standings, but he was denied a push at a podium place when he crashed on the final corner. 

Oliveira beat Mir to the line for second, although the Portuguese rider was initially demoted to third for exceeding track limits on the final lap. It later transpired Mir had also committed the same offence and they were returned to their original positions. 

TOP 10
1. Fabio Quartararo (Monster Yamaha)
2. Miguel Oliveira (Red Bull KTM) +2.592s
3. Joan Mir (Suzuki Ecstar) +3.000s
4. Johann Zarco (Pramac Ducati) +3.535s
5. Brad Binder (Red Bull KTM) +4.903s
6. Jack Miller (Ducati Team) +6.233s
7. Aleix Espargaro (Aprilia Gresini) +8.030s
8. Maverick Vinales (Monster Yamaha) +17.239s
9. Danilo Petrucci (KTM Tech3) +23.296s
10. Valentino Rossi (Petronas Yamaha) +25.146s

CHAMPIONSHIP STANDINGS

Riders

1. Fabio Quartararo (Monster Energy Yamaha) 105
2. Johann Zarco (Pramac Racing) 81
3. Francesco Bagnaia (Ducati Lenevo) 79
4. Jack Miller (Ducati Lenevo) 74
5. Joan Mir (Suzuki Ecstar) 65

Teams

1. Monster Energy Yamaha 169
2. Ducati 153
3. Pramac Racing 102
4. Suzuki Ecstar 88
5. KTM Factory Racing 64

What's next?

The Barcelona-Catalunya circuit plays host to the next race in the championship next weekend, with Quartararo looking for a repeat performance of his win there last year. 

Moto3 rider Jason Dupasquier has died following a crash in qualifying at the Italian Grand Prix on Saturday. 

Swiss rider Dupasquier, 19, was struck by another bike after falling and slid along the track at Mugello. 

After lengthy treatment by medics on the track he was airlifted to Careggi Hospital in Florence.

It was announced on Sunday he had died from his injuries. 

A statement on the MotoGP website read: "Despite the best efforts of circuit medical staff and all those subsequently attending to the Swiss rider, the hospital has announced that Dupasquier has sadly succumbed to his injuries.

"The FIM, IRTA, MSMA and Dorna Sports pass on our deepest condolences to Dupasquier's family, friends, team and loved ones."

Ahead of the Italian Grand Prix, Dupasquier was 10th in the World Championship standings after collecting 27 points from the opening five races of his second season in the competition. 

His team Prustel GP wrote on Instagram: "We're devastated and at this time all of our thoughts are with Jason's family

"You'll be sorely missed and never forgotten, Jason."