The 12 singles pairings for the final round of the Ryder Cup have been announced, with the United States looking to dethrone Europe on Sunday.

Team USA hold a commanding 11-5 lead following Saturday's foursomes and four-ball at Whistling Straits, where the hosts boast the biggest two-day advantage since 1975.

Steve Stricker's USA require just 3.5 points to reclaim the cup from Europe, who will need to produce the biggest ever comeback if they are to claim the required nine points to defend their crown.

"That was an important one," Stricker said after USA split the four afternoon matches. "If they blank us, they're right back in the game. I think getting two points and splitting the session is a good outcome for us."

Xander Schauffele will lead the Americans out to start Sunday's play in Wisconsin, facing struggling European star Rory McIlroy.

McIlroy was dropped for Saturday's foursomes having struggled on Friday – the first time in the four-time major champion's Ryder Cup career that he has missed a session. He returned for the four-ball but fell to another defeat alongside Ian Poulter against Dustin Johnson and Collin Morikawa 4 and 3.

The second matchup pits USA's Patrick Cantlay against Shane Lowry, while Europe captain Padraig Harrington put world number one Jon Rahm down to face Scottie Scheffler.

Bryson DeChambeau and European star Sergio Garcia meet in match four, American Collin Morikawa tackles Viktor Hovland and unbeaten USA veteran Johnson plays Paul Casey.

Elsewhere, Brooks Koepka is set to tee off against Bernd Wiesberger, Poulter and Tony Finau go head-to-head, Justin Thomas will clash with Tyrrell Hatton, Lee Westwood goes up against Harris English, Jordan Spieth faces Tommy Fleetwood and the final matchup is a showdown between Daniel Berger and Matt Fitzpatrick.

United States captain Steve Stricker has selected Jordan Spieth and Xander Schauffele among his wildcard picks for the Ryder Cup, but there is no place for Patrick Reed on the 12-player roster.

Spieth will appear at the biennial competition for a fourth time in a row, while Schauffele is set to make his debut against Europe in next month's tournament at Whistling Straits after recently winning Olympic gold.

Schauffele was one of three rookies chosen by Stricker on Wednesday along with Daniel Berger, Harris English and Scottie Scheffler, with Tony Finau – part of the USA side that lost in Paris three years ago – completing the captain's picks.

Speaking at a news conference to announce his final selection, Stricker said: "All six of these guys have been playing some really good golf for a long period of time. 

"It's more about a body of work. They have all played great throughout this year and very well deserving of these picks."

The top-six qualifiers – Collin Morikawa, Dustin Johnson, Bryson DeChambeau, Brooks Koepka, Justin Thomas and Patrick Cantlay – had already locked in spots for the USA, who are seeking to regain the trophy after that 17.5-10.5 loss in 2018.

Reed is the most notable name overlooked by Stricker, the 31-year-old having featured in every American team since 2014. 

He made his return from a month-long absence at last week's Tour Championship after being hospitalised with pneumonia in both lungs.

Asked to explain his decision to overlook Reed, who top-scored for USA in their 2016 victory at Hazeltine, Stricker said: "That was a very, very difficult call. I lost sleep over that one. 

"He's a tremendous competitor, he brings a lot of match play golf and his record at the Ryder Cup is pretty darn good.

"I think it was the uncertainty of his health and the lack of play that led to our decision down the stretch."

Team Europe captain Padraig Harrington will announce his final three picks on Sunday.

Abraham Ancer thought he had blown his shot at his first PGA Tour win the first time he played the 18th hole on Sunday. Turns out he just needed two more chances on the hole to make it happen. 

Ancer birdied the second playoff hole from six feet and watched as Sam Burns missed almost the same putt to give him the WGC FedEx St. Jude Invitational title as the third man in the playoff, Hideki Matsuyama, also made par. 

After finishing as runner-up four times in his previous 120 Tour starts, Ancer finally prevailed in Memphis to become the ninth first-time winner this season and the fourth player from Mexico to win on Tour. 

"This is surreal," he told CBS. "I thought I left so many shots out there on the back nine, but you never know. Golf is crazy.

"There's been some times that I felt like I made enough birdies to win and I didn't win. This is kind of how it goes and I'm happy that I got lucky."

A significant portion of that luck came on the first playoff hole, when Matsuyama had a chance to win it but saw his long putt for birdie on 18 lip out, sending the trio back to the 18th tee for another go.

The 2021 Masters champion turned in the round of the day just to make the playoff, firing a bogey-free seven-under 63 to fly up the leaderboard on the final day. 

Burns was close behind with a 64, a double bogey on 13 his only blemish. 

Harris English, who held a two-stroke lead after each of the first three rounds, watched those three fly by him as he slumped to a three-over 73 and finished fourth after opening the tournament with rounds of 62, 65 and 65. 

English bogeyed the opening hole before regaining his stride with three birdies, but he did not make another after the eighth hole, posting double bogeys at 11 and 14 and a bogey at the par-five 16th. 

The American said afterward that a warning for slow play on the front nine knocked him out of rhythm and he felt like he was rushing the rest of the day.

His playing partner Bryson DeChambeau had an even more difficult time after working himself into contention with a 63 on Saturday. 

DeChambeau carded a triple-bogey six on the 11th and also did not manage a birdie on the back nine on the way to a 74 that left him tied for eighth at 12 under for the tournament. 

Rough as that triple was for DeChambeau, honours for worst hole of the day went to Kim Si-woo.

The South Korean hit five successive shots in the water at the 11th on the way to a 13 – the worst score on a par-three hole on the PGA Tour since 1983, not including majors.

Among other notables, Dustin Johnson (70) tied for 10th at 11 under, one stroke better than Rory McIlroy (66) and Jordan Spieth (67).

Phil Mickelson (68) finished at seven under along with Louis Oosthuizen, who floundered to a 74 in the final round. 

Sergio Garcia (72), Collin Morikawa (69) and defending champion Justin Thomas (72) were at five under, with Patrick Reed (70) and Lee Westwood (71) one back of them. 

Olympic champion Xander Schauffele (68) was at even par and Brooks Koepka (76) at two over. 

Harris English maintained his two-shot cushion at the WGC-FedEx St. Jude Invitational leaderboard as Bryson DeChambeau climbed up the leaderboard.

Aided by three birdies during his final six holes, English carded a second successive score of 65 at TPC Southwind to sit at 18 under par.

The four-time winner on the PGA Tour endured a bogey-free round on Saturday, pulling clear in the closing stages having at one stage seen both Abraham Ancer and DeChambeau join him in top spot.

After a four at the par-five 16th, English produced an outstanding approach into the green at the next hole before rolling in a birdie putt, boosting his hopes of a wire-to-wire triumph in the tournament.

However, he is well aware that there is still plenty of work to do yet.

"There's a lot of good players behind me and my goal is just stick to my strategy and execute and whatever happens, happens," English said.

DeChambeau is not too far behind after a stunning 63 that saw him come home in just 30 shots. His seven-under score leaves him tied for second with Australian Cameron Smith, who signed for a 65.

"It was awesome being able to strike it that close to the hole all day," DeChambeau, who missed out on playing at the Tokyo Olympics due to contracting coronavirus, said.

"I didn't feel as comfortable as I would have liked with the swing, but the results were there so I was very pleased with the results. And honestly, if I can do that again tomorrow, I give myself a great chance to win."

Ancer is a further two strokes back following a three-under 67, the same score Scottie Scheffler and Ian Poulter both managed to sit just behind the Mexican on 13 under.

Dustin Johnson may still hold out hope of triumphing, with a round of 65 enough to be one of four players on 11 under par.  He is joined by Paul Casey, Will Zalatoris and Louis Oosthuizen.

Defending champion Justin Thomas already faced a battle to retain his crown, and the American was only able to shoot 69 on day three.

At seven under for the event, a repeat of his 2020 triumph appears almost impossible, considering he is so far back and the number of players ahead of him.

Harris English heads into the weekend at the WGC-FedEx St. Jude Invitational with a two-stroke lead after maintaining his spot atop the leaderboard Friday.

The American followed Thursday's 62 with a five-under-par 65 at TPC Southwind, where he won his first PGA Tour title eight years ago. 

Australia's Cameron Smith and Abraham Ancer of Mexico surged into a tie for second place after carding 62s of their own in Memphis to sit at 11 under for the tournament.

Ian Poulter (66), Scottie Scheffler (65) and Sam Burns (64) are three back of the lead at 10 under, while Louis Oosthuizen (64) and Bryson DeChambeau (66) are well within striking distance at nine under. 

English started on the back nine and made three birdies going out before carding his first and only bogey of the day at the par-four second hole. But he managed to follow that disappointment with an eagle on the third before adding one more birdie later in his round.

Smith also eagled the third on the way to tying a PGA Tour record, as he needed just 18 putts to complete his bogey-free round. 

That included a two-put at the last, not long after Smith figured out he was on the verge of history. 

"I was walking down 17 and was counting my putts up and I thought, 'No, that can't be right,'" Smith said. 

Further down the leaderboard, defending champion Justin Thomas (67) is seven strokes back of the lead at six under along with two-time major winner Dustin Johnson (65).

Phil Mickelson (66) is at five under, whie Hideki Matsuyama (69) and Patrick Reed (69) are well back at three under. 

Rory McIlroy (66), Sergio Garcia (68), and Collin Morikawa (71) are at two under, one stroke better than Brooks Koepka (69). 

Jordan Spieth (69) enters the weekend at even par and Olympic champion Xander Schauffele (73) is at two over. 

Harris English won his first PGA Tour title at TPC Southwind eight years ago, and he has another triumph in his sights after opening with a 62 at the WGC-FedEx St. Jude Invitational. 

The American has a two-stroke lead over four pursuers, as Ian Poulter, Carlos Ortiz, Jim Herman and Matthew Wolff carded six-under-par 64s Thursday in Memphis, Tennessee. 

Bryson DeChambeau, Scottie Scheffler and Marc Leishman were three shots back after shooting 65, with DeChambeau making his first start since missing the Tokyo Olympics following a positive COVID-19 test. 

Among the group two shots behind them at five under were defending champion Justin Thomas, Open Championship winner Collin Morikawa and the red-hot Louis Oosthuizen, who has top-three finishes in four of his last five starts.

Among other notables, Patrick Reed and Hideki Matsuyama are at two under, with Phil Mickelson, Dustin Johnson and Olympic champion Xander Schauffele at one under, and Brooks Kopeka and Sergio Garcia at even par.

Jordan Spieth is at one over and Rory McIlroy at two over, leaving him 62nd in the 66-player field. 

But they will all start Friday chasing English. The 32-year-old carded seven birdies on a blistering front nine, then faltered a bit with bogeys at 10 and 12 before closing his round with birdies at three of the last four holes. 

"It was one of those rounds where I was hitting it really good off the tee and making a lot of good putts," English told reporters. 

English won at Memphis in its previous incarnation as the Tour's St. Jude Classic in June 2013, then added another title that fall. 

That was his last PGA Tour win before this year, which has seen him take the Tournament of Champions in Maui in January and the Travelers Championship in June. 

Garrick Higgo overturned a huge deficit to break through for his first PGA Tour title courtesy of a one-shot victory at the Palmetto Championship at Congaree.

Higgo entered the final round trailing by six strokes but the unheralded South African produced a three-under-par 68 to claim his maiden trophy in his second career start on Sunday.

The 22-year-old, who holed an eagle, three birdies and two bogeys, registered the largest comeback on Tour since Bubba Watson in 2018 as he upstaged world number one Dustin Johnson and the chasing pack.

Higgo became the first player to win in one of his first two career PGA Tour starts since Jim Benepe won the 1988 BMW Championship on debut, while he is the youngest winner on Tour this season – aged 22 years, one month and one day.

"It's amazing," Higgo said after finishing 11 under through 72 holes. "I just stayed patient all week. I'm just happy I didn't have to play in a playoff."

Hudson Swafford (66), Doc Redman (67), Jhonattan Vegas (67), Tyrrell Hatton (68), Bo Van Pelt (68) and overnight leader Chesson Hadley (75) ended the inaugural tournament tied for second position.

Ryan Armour (64) and David Lipsky (67) were a stroke further back, while American star Johnson had to settle for a share of 10th place at eight under following his final-round 70 in Gillisonville, South Carolina.

South Carolina native Johnson – who got within one stroke of the lead on the back nine – shot a seven at the par-four 16th hole for his first triple-bogey or worse on the PGA Tour since the 2020 WGC-FedEx St Jude Invitational and the 50th of his career.