Gareth Southgate is set to bring up 50 games in charge when England start their qualifying campaign for the 2022 World Cup.
San Marino are the visitors to Wembley Stadium for the milestone match, with Southgate the seventh to make it to a half-century at the helm for England.
His record so far is impressive: 29 wins, 10 draws and 10 defeats. He has also introduced some notable names to international football, many of which will form the backbone for the Three Lions in this year's delayed Euro 2020 tournament.
In total, 42 players have made their senior debuts under the current boss. Plenty have made an impact, though some have fallen by the wayside since getting a taste of the senior team.
HITS
Jesse Lingard
Lingard is the only member of the current England squad to have made his debut in Southgate's first match in charge, a 2-0 win over Malta in October 2016. The 28-year-old was a key member of the 2018 World Cup squad but has not featured for his country since the Nations League Finals nearly two years ago, having struggled for minutes at Manchester United.
However, a January loan move to West Ham has paid off. No player has been involved in more goals – Lingard has scored five while also providing two assists – since his debut for the Hammers in February. Southgate – who advised the player to remain in the Premier League – has duly taken note, handing him a recall.
Harry Maguire
Maguire made his first England appearance against Lithuania in October 2017, when he was playing for Leicester City. The centre-back quickly established himself in Southgate's side for the World Cup semi-final run, while he has continued to be a mainstay since for the national side.
Indeed, the Manchester United defender has missed just 14 possible outings for club and country since that maiden outing, starting 28 out of England's 30 matches.
Kieran Trippier
Paris was the setting for Trippier's bow, the full-back handed a chance in a 3-2 friendly defeat against France that saw him start alongside then-Tottenham team-mates Eric Dier, Dele Alli and Harry Kane.
Now playing his club football in Spain with Atletico Madrid, the 30-year-old continues to be a key attacking outlet for Southgate's teams. His total of 55 chances created since June 2017 is comfortably the highest for England, with striker Kane second on the list with 37.
Jordan Pickford
No player has both played and started more games for England under Southgate than Pickford, whose debut came in November 2017. With 30 appearances, he sits one ahead of Maguire.
The Everton goalkeeper will not be involved as his manager celebrates his 50th match at the helm, though, as an abdominal muscle injury sees him missing for March's World Cup qualifiers. His absence also offers some of his rivals for the starting job an opportunity to stake their claim to be considered number one, with Pickford's form having been somewhat unconvincing for a while.
Declan Rice
Rice's introduction to action for England came via a substitute appearance during a 5-0 win over the Czech Republic two years ago, replacing Alli just after the hour mark.
The midfielder started all six of the Nations League qualifiers in 2020-21, including scoring his first international goal in a 4-0 triumph over Iceland. As for his club career, only Rio Ferdinand and Joe Cole played more minutes in the Premier League for West Ham than Rice before the age of 22.
MISSES
Nathaniel Chalobah
Having represented England through the youth levels from under-16s upwards, Chalobah has so far played one solitary minute for the senior team, with his late, late opportunity coming against Spain in October 2018.
Since then, the former Chelsea midfielder has started just 42 league games for Watford. This season he is plying his trade in the Championship, contributing three goals and an assist as the Hornets aim for an immediate return to the top flight.
Dominic Solanke
Solanke was part of the England squad that won the 2014 European Under-17 Championship, including scoring in a final against the Netherlands that was eventually settled by a penalty shoot-out.
His senior debut came against Brazil in November 2017, but he has not been involved since. The striker signed for Bournemouth in January 2019 but failed to score in his first 38 Premier League appearances for the club, a barren run finally ended with a brace against Leicester in July 2020. He has been far more prolific in the Championship, getting 11 goals.
Lewis Cook
Cook had success with England at youth level, captaining the squad that went all the way at the Under-20 World Cup. Solanke was also involved in that tournament, along with full internationals Dominic Calvert-Lewin, Ainsley Maitland-Niles, Dean Henderson - who was not first choice in goal - and Fikayo Tomori.
The midfielder's maiden appearance for the senior side earned his grandfather a tidy windfall through a winning bet, but that outing as a substitute against Italy at Wembley remains his only cap. Since then, he has started 58 games for Bournemouth, scoring once.
Jack Cork
Another to be handed a late cameo by Southgate, Cork featured for all of four minutes in a friendly with Germany in November 2017. A young line-up that included new faces Pickford and Ruben Loftus-Cheek managed a 0-0 draw at Wembley.
The midfielder – who was part of the Great Britain squad coached by Stuart Pearce at the 2012 Olympic Games in London – was a regular at Burnley before injuries hampered him in the current season, restricting him to just nine league outings for Sean Dyche's team in the 2020-21 campaign.
Lewis Dunk
Dunk has helped Brighton and Hove Albion rise from League One to the Premier League, with his performances earning him an England opportunity against the United States in November 2018. He started in a 3-0 win that saw Wayne Rooney make his 120th and final appearance for the Three Lions.
The centre-back has not featured since, however, despite remaining a mainstay for his club. Since August 2018, Liverpool's Virgil van Dijk (10) is the only defender to have scored more Premier League goals than Dunk's impressive total of nine.