Dave Rennie pulled no punches as he labelled Australia's 48-17 Rugby Championship hammering at the hands of Argentina as a "massive disappointment" and "not good enough".

The depleted Wallabies were without a host of players including fly-half Quade Cooper, who damaged his Achilles in the opening-round win over the Pumas last weekend.

Even accounting for the absentees, Australia were still pre-match favourites but were completely outclassed in San Juan as Argentina ran in seven tries.

It represented the Pumas' biggest ever win over Australia and moved them top of the standings after two games.

Speaking to Stan Sports after the game, New Zealander Rennie made no excuses for his side's poor performance.

"Massive disappointment. That's not good enough," Rennie said.

"We would [like to have a consistent team list] but we had a good enough side to do the job

"We gave them a few soft points early on and fought our way back into it. We have to do better and we'll get a few players back. Whoever puts the jersey on has to front up but we weren't good enough.

"We conceded four tries with kicks in between us and got dominated in the collision area. We created plenty of opportunities but we have to be patient and our rucks not a disaster.

"We just weren't clinical enough. We definitely lacked cohesion with a few changes. We'll look at the footage but we're better than that."

Australia will look to rebound when they host South Africa in Adelaide on August 27.