Ons Jabeur and in-form Maria Camila Osorio Serrano both progressed to the quarter-finals of the MUSC Health Women's Open.
Top seed Jabeur eased past American world number 313 Alycia Parks 6-4 6-0 in Charleston on Thursday.
Eyeing her first WTA Tour title, Tunisian Jabeur will face Nao Hibino for a place in the semi-finals.
Colombia's Osorio Serrano, who claimed her maiden singles title at the Copa Colsanitas in Bogota last week, rallied past Christina McHale 2-6 7-6 (7-2) 7-6 (7-1).
Osorio Serrano and Clara Tauson will go head-to-head in the quarters at the WTA 250 event.
Linda Fruhvirtova – the 15-year-old Czech teen – and Astra Sharma also advanced at the expense of Emma Navarro and eighth seed Madison Brengle.
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