Serena Williams will face Danka Kovinic in the first round as the American great begins her final US Open campaign.

It will be a final grand slam for 40-year-old Williams, who has won six singles titles in New York and been a runner-up on four occasions.

Her first singles crown in a major came as a 17-year-old at Flushing Meadows, when she beat Martina Hingis in the 1999 final.

Now the end of a glorious career is beckoning for the 23-time singles major winner, who has also landed 16 doubles grand slam titles.

Kovinic is the world number 80 from Montenegro, with the 27-year-old having only won two matches at the US Open in four previous main-draw appearances.

The winner of that match will likely face Estonian second seed Anett Kontaveit in round two. Kontaveit's first-round opponent will be Romanian Jaqueline Adina Cristian.

Defending champion Emma Raducanu, who was a shock winner last year, faces a tricky first-round assignment against France's Alize Cornet.

Cornet is the tour veteran who beat Iga Swiatek at Wimbledon, ending the Pole's 37-match winning streak, and this will be her 64th consecutive grand slam appearance, a record for WTA Tour players.

World number one Swiatek starts against Italian Jasmine Paolini and could face 2017 US Open champion Sloane Stephens in round two.

Former champion Naomi Osaka, unseeded this year, was paired with Danielle Collins, the 19th seed who was an Australian Open runner-up at the start of the year.

The tournament gets under way on Monday.

Men's defending champion Daniil Medvedev faces American Stefan Kozlov in his opener, while Rafael Nadal, who has not lost a grand slam match all year, faces Australian wild card Rinky Hijikata.

Nadal won the Australian Open and French Open titles before pulling out of Wimbledon ahead of his semi-final against Australian Nick Kyrgios due to an abdominal tear.

That handed Kyrgios a bye through to face Novak Djokovic, who got the better of the Australian, but the Serbian must miss the US Open because his refusal to be vaccinated against the COVID-19 virus meant he would not be allowed to enter the United States.

Djokovic's absence was confirmed shortly before the draw was revealed.

Fast-rising Spanish teenager Carlos Alcaraz begins against Argentina's Sebastian Baez, while fourth seed Stefanos Tsitsipas will face a yet-to-be-determined qualifier.

Iga Swiatek's lengthy unbeaten run on clay was brought to a surprise end by Caroline Garcia at the Poland Open on Friday. 

The world number one succumbed to a 6-1 1-6 6-4 defeat to the fifth seed, who ended the French Open champion's 18-match winning streak on the dirt. 

It was Garcia's first win over a top-ranked player and sent her into a semi-final against Jasmine Paolini after the Italian came from behind to beat Viktorija Golubic 1-6 6-2 6-2. 

Swiatek said: "Maybe I wasn't as disciplined as in previous tournaments, but I'm happy. I felt like my brain didn't intuitively predict where the ball would go, but I'm still learning, right? 

"The first two sets depended on her – whether or not she would be in control. At the end of the second she lost control and took advantage. 

"In the third set, she got back to her game. But if I had a better first serve percentage, maybe it would have been different. 

"I don't know what decision I will make next year. Maybe longer preparation [on clay] will be necessarily, or maybe I'll give up this tournament. We'll see." 

Kateryna Baindl became the first lucky loser to reach a WTA Tour semi-final this year by overcoming Petra Martic 1-6 6-3 6-4. Next up for Baindl is Ana Bogdan, who beat Laura Pigossi 6-1 6-1.  

World number two Anett Kontaveit was also on the receiving end of an upset, going down 6-1 6-1 to Anastasia Potapova in 49 minutes at the Prague Open. 

Potapova will take on qualifier Wang Qiang for a place in the final, with Czech pair Marie Bouzkova and Linda Noskova – only the second female player born after 2004 to reach the last four of a WTA Tour tournament – in action on the other side of the draw. 

Bernarda Pera claimed her second WTA title in as many weeks by defeating Anett Kontaveit 6-2 6-4 in the Hamburg European Open final.

The world number 81 continued her rich vein of form, having also captured the Budapest Grand Prix crown last weekend.

Pera, who won four out of six break points, stretched her winning streak to 12 matches, while she has also now reeled off 24 sets without reply.

Kontaveit had prevailed as a commanding straight-sets winner when the pair faced off in the opening round at Wimbledon four weeks ago.

Champion in St Petersburg and runner-up to Iga Swiatek in Doha, the Estonian became the fourth player to appear in at least three finals this season after Swiatek, Ons Jabeur and Veronika Kudermetova.

But the top seed was broken in the opening game by Pera, who won 16 out of 19 points on her first serve as she stormed through the first set.

The American then rescued two break points in the second set, while converting two of her own to secure consecutive breaks and move to the brink of the title.

Kontaveit dug deep; breaking back and winning eight of the next 11 points to stay alive at 5-4, but a long forehand in the next game sealed the deal for Pera.

Second seed Yulia Putintseva was eliminated from the Palermo Ladies Open at the quarter-final stage by Diane Parry on Thursday.

Putintseva was the strong favourite to overcome world number 86 Parry, but it was the latter who prevailed 6-3 6-4 to reach her first tour-level quarter-final.

Caroline Garcia also advanced through after recovering from a heavy first-set loss to overcome Elisabetta Cocciaretto 0-6 6-3 6-4.

Home hope Lucia Bronzetti awaits in the final eight following a 6-1 6-3 win over Elina Avanesyan, while Nuria Parrizas-Diaz beat Julia Grabher 6-2 6-4 in the day's other match.

At the Hamburg European Open, in-form Bernarda Pera beat Katerina Siniakova 6-3 6-1 to make it 10 wins in a row without dropping a set.

Pera is through to her second semi-final in a row, where she will take on Maryna Zanevska, who saw off Aliaksandra Sasnovich in straight sets for a second career top-50 victory.

Top seed Anett Kontaveit advanced after Andrea Petkovic withdrew injured when 6-0 2-0 down, but Barbora Krejcikova was on the end of a 6-1 6-3 upset against Anastasia Potapova.

Anett Kontaveit cruised into the quarter-finals of the Hamburg European Open with a straight-sets win over Rebecca Peterson, while third seed Zhang Shuai was forced out of the Palermo Ladies Open through injury.  

World number two Kontaveit recorded a 6-3 6-2 victory over Peterson on the clay in Germany, setting up a last-eight meeting with eighth seed Andrea Petkovic. 

The Estonian's win was her third over Peterson and maintained her 100 per cent career record against Swedish opponents, taking her to seven such successes. 

Kontaveit was joined in the quarter-finals by fellow seeds Aliaksandra Sasnovich, who beat Aleksandra Krunic 6-3 6-2, and Maryna Zanevska, who downed Alexandra Cadantu-Ignatik 6-4 6-1. 

They will face off for a semi-final spot on Thursday, while Anastasia Potapova will meet 2021 French Open champion Barbora Krejcikova after beating Maria Carle in straight sets. 

At the Palermo Ladies Open, meanwhile, third seed Zhang withdrew from her last-16 clash with home favourite Jasmine Paolini before taking to the court, citing an unspecified injury. 

Fellow seeds Sara Sorribes Tormo and Anna Bondar both reached the quarter-finals with straight-sets wins, however, with the pair set to face off for a semi-final berth on Friday.  

Anett Kontaveit and Barbora Krejcikova both breezed through at the Hamburg European Open, while Yulia Putintseva eased into the Palermo Ladies Open second round.

Top seed Kontaveit overcame world number 61 Irina Bara in straight sets in her first-round clash and third favourite Krejcikova followed suit in her second-round match against Poland's Magdalena Frech.

Kontaveit will meet Sweden's Rebecca Peterson in the next round as she looks to set up a quarter-final meeting in Germany with eighth seed Andrea Petkovic, who defeated Misaki Doi 6-4 6-3 on Tuesday.

There was no such luck for ninth seed Elena Gabriela Ruse, though, after she lost 6-0 6-4 to last week's Budapest Grand Prix winner Bernarda Pera.

Swiss Joanne Zuger will next be the next challenge for Pera as she aims to reach a quarter-final clash against Katerina Siniakova, who triumphed 6-1 6-1 over Brazil's Laura Pigossi.

Putintseva is ranked as the second favourite in Italy and progressed with ease from her first-round clash against world number 147 Jaimee Fourlis, winning 6-3 6-1.

Seventh seed Anna Bondar had little difficulty beating Clara Burel 6-4 6-4, though Caroline Garcia and Nuria Parrizas Diaz faced more difficult tasks in their respective openers.

France's Garcia, the fifth favourite in Palermo, responded to a first-set scare to defeat compatriot Chloe Paquet, while eighth seed Parrizas Diaz also lost her opening set before downing Asia Muhammad.

Jule Niemeier claimed the biggest scalp of her career by knocking second seed Anett Kontaveit out of Wimbledon with an emphatic straight-sets win on Wednesday.

Playing her first match against a top-10 player, world number 97 Niemeier moved into the third round with a 6-4 6-0 victory on No.1 Court.

Kontaveit did not earn a solitary break point as she made another early grand slam exit after falling in the first round at the French Open.

The number-three ranked Estonian, who was knocked out of Wimbledon in the opening round last year, has been suffering from the after-effects of coronavirus over the past couple of months.

German outsider Niemeier was beaten in her first main-draw grand slam match at the French Open last month, but took just 58 minutes to set up a third-round meeting with Anhelina Kalinina or Lesia Tsurenko.

The 22-year-old became the lowest-ranked female player to win a main-draw match at the All England Club against a top-three opponent since Jana Cepelova's defeat of Garbine Muguruza in 2016.

Iga Swiatek and Paula Badosa progressed to the third round of the Internazionali d'Italia with ease as the former continued her impressive winning run on Wednesday.

Top seed Switaek, seeking a fifth consecutive title, breezed past Elena-Gabriela Ruse 6-3 6-0 as she became the first female player to win 24 consecutive matches since Serena Williams in 2015.

Badosa followed suit by dispatching Aliaksandra Sasnovich 6-2 6-1 in just an hour and 17 minutes, teeing up a third-round clash with Daria Kasatkina, who beat Leylah Fernandez 4-6 6-3 7-6 (7-2).

Aryna Sabalenka, the third favourite in Italy, also made light work of Zhang Shuai to triumph 6-2 6-0, while fourth seed Maria Sakkari cruised past Madrid Open semi-finalist Ekaterina Alexandrova 6-3 6-2.

Sakkari will next face a Rome rematch with Coco Gauff, who defeated compatriot Madison Brengle 6-2 6-4. Teenager Gauff's sole win against Sakkari came at this tournament in the second round last year.

Yulia Putintseva came from behind to beat Garbine Muguruza 3-7 7-6 (7-4) 6-1, and will next meet Ons Jabeur, who made it eight successive main-draw wins by defeating Ajla Tomljanovic 7-5 6-2.

Seventh seed Danielle Collins also battled past former world number one Simona Halep 7-6 (7-1) 6-3.

There was no such joy for fifth seed Anett Kontaveit as she crashed out to Petra Martic in straight sets, while Jil Teichmann upset former Rome champion Karolina Pliskova in a three-set thriller.

Belinda Bencic, who was ranked as 12th seed, was another early casualty as she fell to a 7-6 (7-4) 6-1 defeat against American Amanda Anisimova.

Meanwhile, Jessica Pegula secured her third-round spot after Anhelina Kalinina withdrew due to injury, with Victoria Azarenka earning a straightforward 6-2 6-4 victory over Camila Osorio to get a shot at favourite Swiatek in the next round.

Iga Swiatek continued her impressive form as she crushed qualifier Eva Lys at the Stuttgart Open to clinch a 20th successive win and sail into the quarter-finals.

The world number one was far too good for her opponent, as she claimed her 6-1 6-1 victory in slightly over an hour.

Swiatek, 20, last lost a match in February and has not dropped a set since Indian Wells in March, winning each of the last 26 – that is the best such run on the WTA Tour since Serena Williams won 28 successive sets between the 2012 US Open and 2013 Australian Open.

Having won each of the past three events she has entered, Swiatek is the hot favourite to make it four on the bounce in Stuttgart, where she could meet reigning US Open champion Emma Raducanu next in the last eight.

Raducanu, seeded eighth, began her campaign with an emphatic 6-1 6-2 win over Australia's Storm Sanders on Wednesday to set up a second-round clash with Tamara Korpatsch – the winner faces Swiatek.

Sixth seed Karolina Pliskova overcame compatriot Petra Kvitova 6-4 4-6 7-6 (7-5) to progress, while Anett Kontaveit – the fifth favourite – saw off Angelique Kerber 3-6 6-4 6-4.

It was a bad day for some of the higher seeds in the Istanbul Cup, as three of the top five were eliminated.

Favourite Elise Mertens retired from her tournament opener with Rebecca Peterson due to a leg injury, though the Belgian was already 7-5 4-1 down.

Anhelina Kalinina and Jil Teichmann – seeded fourth and fifth, respectively – suffered surprise defeats as well.

Defending champion and second seed Sorana Cirstea appeared in danger of following them out as well, but rallied to defeat Arantxa Rus 3-6 6-1 7-5.

Ajla Tomljanovic also progressed, the Australian enjoying an impressive start against her countrywoman Jaimee Fourlis, winning 6-1 6-3.

Naomi Osaka is through to the third round of the Miami Open after beating former world number one Angelique Kerber in straight sets.

Osaka won the first three games of the match to jump out to an early lead, securing the set with a double-break before breaking early in the second to cruise to a 6-2 6-3 win.

The story of the match was Osaka's ease in winning points against Kerber's serve, winning 41 per cent (15/37) of Kerber's successful first serves, while the German could only win 11 per cent (3/27) in the same category.

Britain's top-ranked woman Emma Raducanu suffered another early exit, on the wrong end of Katerina Siniakova's comeback 3-6 6-4 7-5 win.

World number five Anett Kontaveit slipped out of the Indian Wells Open after a 3-6 7-5 7-6 (7-5)  loss to Marketa Vondrousova.

Kontaveit was the second-highest seed remaining in the tournament entering Monday's play, and appeared to be on her way through to the fourth round after breaking twice in the opening set.

Yet Vondrousova got the better of her Polish opponent in a topsy turvy second set, forcing a decider that starter in frantic fashion, with a concession of serve in each of the opening five games.

Vondrousova held to end that street yet was pulled back to 4-4 by a resurgent Kontaveit, though the Czech world number 33 eventually closed the match out at the fourth time of asking in the tie-break to tee up a clash with Veronika Kudermetova.

Iga Swiatek thrashed Anett Kontaveit on Saturday to win the Qatar Ladies Open title.

The world number eight triumphed 6-2 6-0 to win her first Tour title of 2022 and the fourth of her career.

Swiatek, who has now claimed two titles at the WTA 1000 level, won the final 10 games of the contest as Kontaveit was powerless to stop her nine-match winning streak coming to an end.

The 2020 French Open champion Swiatek has only dropped 11 games in the four finals she has won.

Kontaveit fought back to 2-2 after an early break of serve, but that was the last time she would win a game as Swiatek took control.

Having survived break points to see out the opening set, Swiatek powered through the second, dropping just four points on serve as she raced to victory in 66 minutes.

Swiatek has now won her last three matches against Kontaveit, taking the overall head-to-head record to 3-2 wins in her favour.

Anett Kontaveit defeated Jelena Ostapenko in straight sets, while Iga Swiatek overcame Maria Sakkari to secure her place in the Qatar Ladies Open final.

Swiatek advanced to the Doha showpiece for the first time after managing her first win over Sakkari in four attempts with a 6-4 6-3 triumph on Friday.

The Pole was in imperious form as she delivered 20 winners to overcome sixth seed Sakkari in an hour and 28 minutes, collecting her seventh top-10 win and second straight such win after defeating Aryna Sabalenka in the quarter-finals.

The seventh seed will now meet Kontaveit, who continued her impressive streak with a 6-1 6-4 win over Ostapenko in just 68 minutes.

Ostapenko headed into the clash on a career-best nine-match winning run, but succumbed to her fourth loss in five meetings with the fourth seed in Qatar.

Ostapenko did have back-to-back break points at 5-5 in the final set, but Kontaveit managed to hold on for victory.

"She can outplay anyone, and then she might not find the consistency sometimes, so you have to be ready for that," Kontaveit said of Ostapenko.

"I was trying to play a consistent match and just do my best on my serve and hold on to it, especially in the second set when I was a break up.

"Sometimes when she's on fire, her returns are unplayable and it's just very difficult.

"But I kept repeating to myself, 'I'm really good at serving it out, I'm really good at serving it out,' and eventually managed to do that.

"How you approach the match, how you're approaching the service games, I think if you're trying to be aggressive [...] that has a lot of effect on the serve."

It will be the seventh final that Kontaveit has contested since last August, converting those appearances into five titles so far. Kontaveit and Swiatek share a pair of wins apiece in previous clashes.

Anett Kontaveit remained on course for a sixth title in seven months, progressing to the Qatar Open semi-finals after defeating Ons Jabeur in straight sets.

Champion in St Petersburg two weeks ago, Kontaveit extended her winning run to eight matches following a 6-4 6-1 success.

The opening set was neck and neck until Kontaveit won 15 out of 16 points from 30-30 at 4-4 to draw first blood and establish a 2-0 lead in the second.

The Estonian, who registered just 12 unforced errors throughout the contest, then took 12 of the last 15 points to advance to the last four. 

"At times, it was just kind of fun because I felt like the level was really good, and I was playing really well," said Kontaveit, who has won nine of her last 13 matches against top-10 opposition.

"I think I have this confidence that I can go deep every week that I'm playing, and I'm not setting these mental barriers to myself that I used to do. 

"I'm very happy with being in the semi-finals, but I also feel like I can still go deeper, I can still do more. So, I'm not too satisfied yet with this result. I feel like if I play well or if I'm consistent, I have a chance with anyone.

"I'm really happy that I'm bringing a good level of tennis consistently every tournament. I think that's something that I'm just most pleased with."

In the semi-finals, Kontaveit will face another in-form player in Jelena Ostapenko, who saw off Garbine Muguruza in straight sets.

Having triumphed in Dubai last week, the 15th seed has now recorded nine successive victories for the first time in her career after prevailing 6-2 6-2.

Ostapenko struck 39 winners and claimed 15 of 18 points on her opponent's second serve as she moved a step closer to a maiden title in Doha, having reached the final six years ago.

Meanwhile, Iga Swiatek is through to her first WTA 1000 semi-final on a hard court after a 6-2 6-3 win over Aryna Sabalenka.

The former French Open champion won seven out of eight breakpoints, while reeling off six successive games in the second set to secure a comfortable victory.

Next up for her is Maria Sakkari, who recorded her third win against Coco Gauff in four meetings after prevailing 6-3 6-3.

The sixth seed is through to her sixth semi-final at WTA 1000 level or above – and targeting her first such title.