Derwin James knows the Los Angeles Chargers have no room for error following their Week 13 defeat to the Las Vegas Raiders.

The Chargers, having claimed a dramatic win over the Arizona Cardinals in Week 12, bumped back down to earth with a 27-20 loss at Allegiant Stadium.

It leaves the Chargers 6-6 and a game adrift of the New York Jets in the final Wild Card place in the AFC playoff picture.

They now face a critical home game with the 8-4 Miami Dolphins, and safety James believes they can ill-afford any further slip-ups if they are to make the playoffs for the first time since 2018.

"We gotta keep playing. There's more games to be played. Prime time next week. We gotta come out [with a] sense of urgency," said James.

"Each game from here on out, we can't lose anymore. We gotta win out."

The Chargers' run defense was again a problem area for Los Angeles, allowing Josh Jacobs to rush for 144 yards and a second-quarter touchdown.

Los Angeles' defense is allowing 5.43 yards per rush in 2022, the most in the NFL, and head coach Brandon Staley blamed poor tackling for their struggles.

"I thought we played well early," Staley said of their efforts to stop Jacobs.

"I thought there were some missed tackles in the second half, which led to most of his yards. I thought we were in good run structures but missing tackles. He forces people to miss.

"No one is out there trying to miss. He's a good back and that's going to happen. I really felt like we defended well in the first half outside of a couple of misses. In the second half, it was a little up and down.

"Guys just have to tackle better."

The Tennessee Titans are at a crossroads in their season, according to head coach Mike Vrabel, after they were thrashed by the Philadelphia Eagles in Week 13.

Vrabel saw his team crushed 35-10 at Lincoln Financial Field as the Eagles improved to 11-1 in an outstanding season.

Former Titans wide receiver A.J. Brown, traded to the Eagles on draft day this year, had eight catches for 119 yards and two touchdowns against his former team in a superb display.

For Tennessee, the blowout loss comes on the heels of a narrow loss to the Cincinnati Bengals, dropping them to 7-5.

The Titans are almost certainly going to win a poor AFC South division, but these back-to-back defeats raise substantial questions about Tennessee's ability to contend for postseason success.

"I think we are at a crossroads," Vrabel said. "I told the team I think we are at a crossroads at kind of how we want to continue down this season.

"We can't point fingers. We have to assume that each and every one of us didn't do a good enough job because we didn't.

"We have to come to work with greater energy and greater resolve to prepare to win a football game against a division opponent.

"It sucks losing, it sucks getting beat the way we did but we have to make a decision, how much are we willing to invest and trust in what the coaches are doing, trust in what each of the players are doing. I think it’s a critical time for us."

The Titans will be favoured to get back on track next week when they host the Jacksonville Jaguars on Sunday.

Baker Mayfield will be released by the Carolina Panthers on Monday, bringing an end to a brief and disappointing stint with the franchise.

The first overall pick of the 2018 NFL Draft was traded away by the Cleveland Browns in July, with the Panthers giving up a conditional fifth-round draft pick.

After competing with Sam Darnold for the starting quarterback berth, Mayfield started the season as QB1 until suffering a high-ankle sprain in a Week 5 loss to the San Francisco 49ers – returning in Week 8, when he was backup for P.J. Walker.

Having made his last appearance in a Week 11 defeat to the Baltimore Ravens, the NFL Network's Ian Rapoport reported Mayfield will be released by the Panthers and will hit the waiver wire on Monday.

Mayfield will depart the Panthers with a disappointing 1-6 record, throwing as many interceptions as touchdown passes (six).

A pass completion percentage of just 57.8 per cent is the second-worst across the NFL, only ahead of the New York Jets' Zach Wilson (55.6 per cent).

Bill Belichick believes it is too late in the season to rip up the playbook for the New England Patriots, even as the perennial contenders continue to struggle with their form.

A 24-10 loss to the Buffalo Bills last Thursday saw the Foxborough outfit drop to 6-6 for the season, leaving them outside the AFC's wild card slots with a handful of games to go.

Though there is plenty of time to still salvage their season, the Patriots appear to be in something of a rut, with quarterback Mac Jones involved in a sideline outburst last week.

Belichick, however, will not introduce wholesale changes, claiming they are too deep into the season to do so, and stating they merely need to execute their existing tactics.

"I think we need to do what we're doing better," he told radio station WEEI. "I don't think at this point making a lot of dramatic changes. It's too hard to do that.

"If we can just do, consistently, what we're doing, I think we'll be all right. We just haven't been able to have enough consistency. That's hurt us.

"It's not one thing. One time, it's one thing, [and] next time, it's something else. We just have to play and coach more consistently.

"I think we'd all certainly like to be doing better than what we've been doing, from a record standpoint and from an individual execution [standpoint]. But we're going to look ahead and not backward."

The Patriots are not in action for another week now, and will return to the field against the struggling Arizona Cardinals next Monday.

Kyle Shanahan believes the San Francisco 49ers will still "have a chance" with quarterback Brock Purdy after he was thrust into the starting role following a season-ending injury to Jimmy Garoppolo.

Garoppolo suffered a broken foot on the 49ers' first drive of their thrilling 33-17 win over the Miami Dolphins on Sunday, which maintained San Francisco's one-game lead atop the NFC West at 8-4.

Purdy was the final pick in the draft this year, earning him the tag 'Mr Irrelevant', but he is now the focus of San Francisco's season after an encouraging performance in relief of Garoppolo.

The former Iowa State quarterback completed 25 of his 37 passes for 210 yards, two touchdowns and an interception, the Niners outscoring the Dolphins 30-10 after Garoppolo left the game as San Francisco's top-ranked defense rattled Tua Tagovailoa and the NFL's most explosive offense.

Now the 49ers, a team who had Super Bowl aspirations with Garoppolo under center after he took over from injured 2021 third overall pick Trey Lance, must try to achieve their goals with Purdy under center.

While most may believe their hopes are now over, Shanahan is not giving up.

"What impressed me about Brock in [training] camp," Shanahan said, "is he was always willing to let it rip.

"He's decisive. He started for years [at Iowa State] at a high level. You gotta have some balls to play quarterback in this league, and he does. We think we'll have a chance with him."

Purdy will this week prepare for his first start, which will come against the man regarded as the greatest of all time, Tom Brady, and the Tampa Bay Buccaneers.

"Pretty cool," Purdy told King when asked about going against Brady. "The GOAT. He's been playing football longer than I've been alive."

But Purdy knows he will not have to do it alone, as he enters arguably the best offensive ecosystem in the NFL with Shanahan calling the plays for an attack stacked with weapons, and he also has the assistance of a defense that forced three turnovers from Tagovailoa as the 49ers beat a team led by former offensive coordinator Mike McDaniel.

"I know the question is, can I step in and continue this ride of what our team has done?" added Purdy.

"It's not just a one-man show or anything like that. What Jimmy did for this team was amazing in terms of getting it rolling and getting us on a streak to win.

"The challenge for me is like, man, can I step up in that position and continue to feed those guys? Get them the ball. Make the right checks in the run game. Allow the defense to play great and play with them. That's the challenge for me and that's how I look at it and I'm excited for it."

Aaron Rodgers always felt confident the Green Bay Packers would rally to triumph in a "special rivalry" with the Chicago Bears and revelled in helping the franchise make NFL history.

Trailing 19-10 through three quarters, the Packers outscored the Bears 18-0 in the fourth to run out 28-19 winners and rack up an eighth straight victory in matches between the two teams.

Back in October 2021, Rodgers went viral for yelling "I own you" at Bears fans during a typically volatile 24-14 win.

Sunday was by vintage Rodgers, who has been contending with a broken thumb since October and injured his ribs against the Philadelphia Eagles last week, but he completed 18 of 31 passes for 182 yards and a touchdown en route to improving to 25-5 against the Bears.

Asked whether this continued his "ownership" of the Bears, Rodgers replied: "Yes.

"We've got a special rivalry that I've been able to be a part of and there was probably a lot of people that felt good at 19-10, so did I.

"A win against the Bears is always a little more special, there was other things involved, the all-time win total was cool, another fourth-quarter comeback.

"I told the guys in the locker room we've played good enough at times to beat anyone in the league, and at times played poor enough to lose to just about anybody."

With the win, the Packers moved outright top on the list of all-time NFL victories at 787, one clear of the Bears in second.

It is a statistic Rodgers takes great pride in.

"It means a lot, part of the legacy is you always want to leave the place you're at better than you found it," he said.

"Right now, we flipped the all-time series [versus the Bears], all-time wins, we've had a lot of success against them.

"In a few years you'll look back and feel pretty good about your contributions to the rivalry."

Joe Burrow got the better of Patrick Mahomes once again and is playing at an "MVP level" according to his Cincinnati Bengals head coach Zac Taylor.

The Bengals earned a 27-24 triumph over the Kansas City Chiefs at Paul Brown Stadium and moved to 8-4 for the season.

Burrow was once again influential as he moved to a perfect 3-0 in games played against quarterback rival Mahomes, whose Chiefs sit at 9-3.

The 25-year-old completed 25 of his 31 passes, including touchdown passes to Tee Higgins in the second quarter and Chris Evans in the last, with Evans' score putting the Bengals up for good.

"He's playing at an MVP level – absolutely," Taylor said. "He gives us a lot of confidence."

Burrow's outing also included running in a four-yard score and converting on a couple of third-down passes to Ja'Marr Chase and Higgins that allowed the Bengals to run down the clock.

After the game, Burrow said: "We left some points on the field, but we still find a way to win.

"We've still got five weeks left. Let's keep this train rolling. This team knows what it takes to win these games. We've been there. It's December. It's time to separate ourselves."

Wide receiver Chase missed the previous four games with a hip injury and last year's Offensive Rookie of the Year caught seven passes for 97 yards on a brilliant return.

"I was surprised at how quickly he was looking like the same Ja'Marr, even in practice last week. He's a freak," Taylor added.

Mahomes finished the game with 16 of 27 passes completed for 223 yards and a touchdown, while running in for another score.

But the Chiefs quarterback rued some costly mistakes.

"We started off slow, we got back in the game, into the flow of things and [then] we had a turnover late and a missed kick," he said.

"In the fourth quarter, those are the things that kind of bite you at the end."

Miami Dolphins quarterback Tua Tagovailoa downplayed the severity of an ankle injury that forced him out late in Sunday's 33-17 loss to the San Francisco 49ers.

Tagovailoa, who completed 18 of 33 passes for 295 yards and two touchdowns with three turnovers, did not partake in the Dolphins' final drive and was listed as questionable to return.

That came after being listed on the injury report during the week with an ankle injury although he was able to fully participate in team practices.

"As good as I can be coming off a game," Tagovailoa told reporters after Sunday's defeat. "We'll assess some things but as good as I can be."

Tagovailoa's two interceptions came on successive passes in the third quarter. The third-year quarterback had given up three turnovers all season coming into Week 13.

The result leaves the Dolphins with an 8-4 record, with the Buffalo Bills on top of the AFC East with a 9-3 record fueled by a three-game win streak.

The Dolphins' own five-game win streak was ended by the 49ers and Tagovailoa lamented his performance.

"It sucks," he said. "It sucks that we didn't come out and do what we wanted to do as a team.

"Obviously, it starts with me - turnovers, with third-down communication errors. In that retrospect, it's hard to win a game when you're not on your P's and Q's and you're not dialed in.

"A lot of that has to do with understanding what we're trying to accomplish and what we're trying to do. It was definitely a poor performance from my part in that aspect of the game."

The Dallas Cowboys' defense woke up in the second half to run away with a 54-19 home win against the Indianapolis Colts on Sunday, led by former Colts safety Malik Hooker.

The win improved the Cowboys' record to 9-3, good enough for third in the NFC, trailing only the Philadelphia Eagles (11-1) and the Minnesota Vikings (10-2) in the race for the one seed.

It was the Colts leading early, with Matt Ryan's 14-yard touchdown pass to Ashton Dulin giving them a 10-7 lead at quarter-time after their opening field goal was answered by a CeeDee Lamb touchdown catch for the Cowboys.

Tony Pollard put the Cowboys back in front when he forced his way into the endzone from the two-yard line, before Hooker seized full control of the game when he intercepted Ryan with one minute remaining in the first half, allowing the Cowboys to add another touchdown ahead of the break.

Michael Gallup was the recipient of that score in the final seconds of the half, and after an Alec Pierce touchdown cut the Cowboys' lead to 21-19, Gallup snagged his second of the game for some breathing room.

Things would go from bad-to-worse from there for the Colts as their next four drives resulted in turnovers.

Hooker added a fumble recovery and defensive touchdown to his big day, and the next two drives would both end in interceptions by fifth-round rookie DaRon Bland, icing the game and setting up some garbage-time stat-padding.

Dak Prescott completed 20 of his 30 passes for 170 yards, three touchdowns and one interception, while Pollard rushed 12 times for 91 yards and two scores, and Ezekiel Elliott added 17 carries for 77 yards and a touchdown of his own.

San Francisco 49ers head coach Kyle Shanahan called it "crushing" to lose starting quarterback Jimmy Garoppolo for the rest of the season after he broke his foot in Sunday's 33-17 win against the Miami Dolphins.

Garoppolo's injury came on the 49ers' eighth offensive play of the game, when he was sacked by both Jaelan Phillips and Jerome Baker to end their first drive. He stayed down, and ended up being carted off the field and promptly ruled out.

After the game it was revealed he had sustained broken bones in his foot, requiring season-ending surgery.

Starting the campaign as the third-string quarterback, Brock Purdy came in and threw two touchdown passes, managing the game efficiently before the 49ers' defense snagged a fumble-return touchdown to pull away.

Shanahan said it hurts to lose Garoppolo, but gave plenty of respect to Purdy for the performance.

"Just hearing it, it was pretty crushing," he told reporters. "We know what Jimmy has been through, how hard he's worked at this. He'll be out. He'll need surgery, broke a few things in there.

"Brock came in and made some big plays. We've got to clean some stuff up, obviously, but just throwing him in there in the heat of battle like that, [with] how much [all-out pressure] that team did, too, which you guys can see.

"We were having to change a lot of stuff on the fly, so putting a lot of pressure on [Purdy] in that way. I thought he did a hell of a job doing it. Protected the ball well, didn't have any turnovers and made some big plays too that I thought weren't there always."

The 49ers ruled out any possibility for Week 1 starter Trey Lance returning in time for a playoff run, meaning it will be Purdy the rest of the way, and he will make his first career start next week when Tom Brady and the Tampa Bay Buccaneers come to town.

"It’s gonna be pretty cool," Purdy said. "[Brady] has been playing football longer than I’ve been alive."

In fact, Brady played his final college game at Michigan four days after 22-year-old Purdy was born.

Defensive captain Fred Warner showed no signs of panic after he heard the news of Purdy's rise to the top of the depth chart, saying all his repetitions against this incredible 49ers defense in practice should have him ready.

"He's played against the best defense in the league for the past 13 weeks," he said. "He'll be fine."

The Cincinnati Bengals had strong contributions from all facets of their offense to defeat the Kansas City Chiefs 27-24 on Sunday.

In a rematch from last season's AFC Championship game – where the Bengals beat the Chiefs to advance to the Super Bowl – quarterback Joe Burrow was at his sharpest.

The 25-year-old former top overall draft pick completed 25 of his 31 passes, including touchdown passes to Tee Higgins in the second quarter and Chris Evans in the last, with Evans' score putting the Bengals up for good.

In his return from a five-game injury absence, last year's Offensive Rookie of the Year Ja'Marr Chase picked up right where he left off as Burrow's top option, catching seven passes for 97 yards, but backup running back Samaje Perine was even more influential.

Perine was used heavily in the fourth quarter as the Bengals looked to claw their way back from a deficit, with three of his six catches coming on their go-ahead touchdown drive, finishing with 49 yards through the air and another 106 on the ground from 21 carries.

It was not the best game from Chiefs quarterback and MVP favourite Patrick Mahomes, with 223 yards and one touchdown, as the Bengals committed to dropping eight defenders into coverage all game, forcing the Chiefs to accept small gains instead of their usual chunk-plays.

With the win, the Bengals are now 8-4, joining the Baltimore Ravens in a tie for the AFC North lead, while the Chiefs are three games clear atop the AFC West at 9-3.

Purdy party keeps the 49ers rolling

Brock Purdy was able to deliver a big 33-17 win for the San Francisco 49ers against the Miami Dolphins, but it came at a cost.

Purdy, the very last pick in this year's NFL Draft, was called upon when starting quarterback Jimmy Garoppolo was carted off and ruled out during their first drive of the game. Garoppolo has been diagnosed with a broken foot, with the team saying afterwards that it will end his season.

Almost a lock for the playoffs now at 8-4 with arguably the best defense in the league, the 49ers will need Purdy to get up to speed in a hurry if they still have dreams of a Super Bowl run, and he was solid against the Dolphins, completing 25 of his 37 passes for 210 yards, two touchdowns and one interception.

Deshaun Watson struggled on his return from an 11-game suspension where he was booed throughout as the Cleveland Browns won on the road against the Houston Texans 27-14 on Sunday.

Watson, who had been banned for violating the NFL's personal conduct policy for allegedly committing sexual assault, completed 12 of his 22 attempts for 131 yards with no touchdown passes and one interception.

The Browns' defense picked up Watson with two defensive touchdowns and a punt-return score to improve their record to 5-7, sitting third in the AFC North.

The three-time Pro Bowl quarterback had left the Texans for the Browns in the offseason on a five-year deal worth $230million guaranteed, one of the richest and most guaranteed contracts in NFL history.

That trade came after Watson had not played in the 2021 season as accusations emerged from more than two dozen women of sexual assault and other sexual misconduct during massage sessions, leading to the NFL-imposed 11-game ban and record $5m fine in August.

Watson's first NFL regular-season game in 700 days was met with displeasure, with his former fans booing and jeering him throughout.

"They're supposed to boo," Watson told reporters after the game. "I'm a Cleveland Brown now, and we're on the road, so they're supposed to boo."

Watson again refused to answer any non-football questions after the game, having been asked if he had any remorse for his actions that led to his suspension.

"That's something that, legal and clinical, we've answered before," Watson said. "They don't want me to address anything like that.

"Of course, it was a tough situation. The suspension was tough. But at the same time, my main focus is just trying to be 1-0 as a football player today.

"I was just excited to be back on the field today. I did everything that I was asked and was required to do. I did all that. I was able to play and be on the field today."

Browns head coach Kevin Stefanski conceded Watson was rusty after not played for a season-and-a-half.

"Obviously you're missing a bunch of time so you've got to get back in it," Stefanski said. "You've got to get this first one out of the way. But I know what the kid is capable of."

The Browns face the 8-4 Cincinnati Bengals next Sunday.

Quarterback Lamar Jackson's knee injury is not considered season-ending, according to Baltimore Ravens coach John Harbaugh.

Jackson will undergo tests on Monday, and the team will have an idea by Wednesday on the severity of the injury and how much time he will miss – if any.

"It's going to be a number, days-to-weeks. We'll see," Harbaugh said after Sunday’s 10-9 win over the Denver Broncos. "We'll see if you can go back this week. If not, it'll be sometime after that shortly."

The 2019 league MVP was injured on the final play of the first quarter, when he landed awkwardly while being sacked from behind by linebacker Jonathon Cooper.

He was then evaluated in the sideline medical tent and sent to the locker room, leaving backup Tyler Huntley to run the offense.

The Ravens' offense struggled mightily Sunday, managing 268 total yards over the final three quarters and didn’t reach the endzone until 28 seconds left in the game, when Huntley scored on a game-winning two-yard touchdown run.

If Jackson’s injury is deemed serious and he ends up missing time, it could not only be detrimental to Baltimore’s playoff hopes, but also factor into Jackson’s next contract.

Jackson, who will be a free agent after this season after contract talks with the Ravens broke down over the summer, hadn’t missed time since suffering a season-ending ankle injury in Week 14 of 2021, which ultimately cause the Ravens' season to unravel.

Baltimore was 8-4 and atop the AFC North after 13 weeks last season, but ended up losing the last five games after Jackson went down and missed the playoffs.

The Ravens entered this week tied with the Cincinnati Bengals atop the AFC North, and improved their record to 8-4.

San Francisco 49ers starting quarterback Jimmy Garoppolo was carted off the field and ruled out of Sunday's game against the Miami Dolphins after only eight plays.

Garoppolo was sacked by Dolphins duo Jaelan Phillips and Jerome Baker on the 49ers' first drive, staying down and eventually needing the cart to carry him back down the tunnel.

He was swiftly ruled out of the remainder of the contest due to the foot injury he sustained, with rookie Brock Purdy brought in as the 49ers' new signal-caller. Purdy was the very last pick in this year's NFL Draft, earning him the title of 'Mr Irrelevant'.

Nevertheless, Purdy closed the first half in style, delivering short-range touchdown passes to Christian McCaffrey and Kyle Juszczyk to head into the break with the 49ers leading 17-10.

At 7-4 while boasting arguably the best defense in the NFL, the 49ers' Super Bowl dreams will take a massive hit if Garoppolo's injury keeps him on the sideline for an extended period.

The Minnesota Vikings took another big stride towards the playoffs with a 27-22 victory over the New York Jets, courtesy of fine showing in the second quarter.

All square with a field goal each in the first quarter, the Vikings hit boiling point to score 17 points without return to enter the half with a commanding lead.

A rushing touchdown each from Dalvin Cook, his eighth of the year, and Alexander Mattison left the Jets needing a response from the third quarter in order to maintain hope for their own postseason push.

The Jets did exactly that, scoring 12 unanswered points, all from the boot of Greg Zuerlein, to claw their way back into the game – Mike White then scoring a touchdown in the fourth on the Jets' immediate possession after Justin Jefferson added further gloss to the Vikings advantage.

It was not to be though, as Braxton Barrios dropped a pass in the endzone for the Jets, before White's last-ditch throw on the final possession was picked off at the goal line by Camryn Bynum to clinch a tenth win of the season for Minnesota.

However, with the Detroit Lions 40-14 victors against the Jaguars, the Vikings did not get the favour they needed from Jacksonville and will have to wait to cement their postseason spot.

Packers lead the way

The Green Bay Packers scored 17 straight fourth-quarter points, as well as a blocked field goal and two interceptions, on their way to a comeback victory against the Chicago Bears – which created NFL history.

Trailing 10-0 and 16-3 in the first half, Aaron Rodgers' side fought back to seal a 28-19 win and became the NFL's all-time winningest franchise, taking their franchise total to 787.

Honours even between Commanders and Giants

The divisional rivalry between the Washington Commanders and New York Giants went all the way into overtime, after Taylor Heinicke's 28-yard touchdown pass to Jahan Dotson levelled the score at 20-20 to end the fourth quarter.

Neither side managed to get the score they needed to secure what would have been a valuable win for the playoff charge, resulting in the first tie between the two franchises since 1997 and only the fifth all-time.