It seems bizarre to suggest that in a contest between a club that has never won the European Cup or Champions League and another that has won 13 of them, it is the latter who will go into it as the underdog.
That is the case this week, though, with Manchester City and Real Madrid set to go head-to-head for a place in this season's Champions League final.
There is obviously reasoning behind this, with Pep Guardiola's side winning every other trophy available to them in recent years and breezing through their European campaign up to this point, a few scars from their quarter-final with Atletico Madrid aside.
Carlo Ancelotti's men have had a tougher road to get here, having to get past newly crowned French champions Paris Saint-Germain and reigning European champions Chelsea so far in the knockout stages.
They had to produce stirring comebacks in both ties, but City are an altogether different prospect, having finished above PSG in the group stage and beaten Chelsea home and away in the Premier League this season.
The English side have very few obvious weaknesses, but perhaps there is one area where Ancelotti can focus ahead of the first leg in Manchester.
Guardiola has recently been slightly overstating his lack of options, saying before the game with Watford at the weekend that City were suffering an injury crisis, before using 14 players that cost approximately £695million (€825m) (according to Transfermarkt.co.uk) to beat the Hornets 5-1.
However, one of his star performers this season has undoubtedly been Joao Cancelo, and the Portuguese full-back is suspended for the first clash with Madrid, while Kyle Walker remains a doubt with an ankle injury.
"They are doubts," the City manager said at a news conference on Monday when asked about Walker and John Stones. "They didn't train for the last week, 10 days... We will see how they feel and take a decision tomorrow."
This could lead to Guardiola having to get a bit creative at right-back, with Oleksandr Zinchenko presumably getting the nod on the left.
Most eyes will be on the likes of Karim Benzema and Luka Modric to lead the visitors, with both producing their usual big-game performances to make the difference against PSG and Chelsea, but the key at the Etihad Stadium may be another slightly unsung hero.
It's not that Vinicius Junior is not highly rated. This season he has exploded into one of the most potent attackers in world football, but this could be the perfect time for him to cement his name as a star of Real Madrid's present and future.
The Brazilian has always been considered a talent but could never quite put together the consistent run of form expected of regular starters in the famous all-white kit, until this season.
Vinicius has registered 31 goal involvements (17 goals, 14 assists) in 45 games in all competitions (42 starts), and has created 94 chances from open play.
Compare this to last season and you can see his significant improvement, managing just 10 goal involvements (six goals, four assists) in 49 appearances (31 starts) in 2020-21, with just 43 chances created from open play.
His numbers are now up there with the best in Europe. In terms of chances created from open play in the top five European leagues this season, only Bruno Fernandes (101) and Thomas Muller (100) have created more than his 94.
No-one has attempted more than his 303 dribbles this season, while only Adama Traore, Kylian Mbappe (both 137) and Allan Saint-Maximin (136) have completed more dribbles than his 127.
Vinicius is well established as a standout performer in LaLiga this season as well, with only Benzema (25), Enes Unal and Raul de Tomas (both 15) having scored more than his 14, while only Benzema (36) has more goal involvements than his 22.
Speaking of Benzema, his partnership with the 34-year-old marksman is developing into one of the most potent in the game, with the duo having provided the most goals for each other in the Champions League this season (six), ahead of Ajax's Antony and Sebastian Haller, and Bayern Munich's Leroy Sane and Muller (both four).
Vinicius is always a threat, as shown against Chelsea at the Santiago Bernabeu in the second leg of their Champions League quarter-final. Blues right-back Reece James had been doing a good job of containing him, until one switch off in extra time allowed the 21-year-old down the left, and he played a perfect cross in for Benzema to score what proved to be the winning goal in the tie.
There is another Brazilian winger for City to potentially watch out for, though, in Rodrygo, who also played a crucial role in dumping out Chelsea by scoring moments after coming off the bench in the second leg.
While he has certainly not emerged like Vinicius just yet, the former Santos player has been making himself a more integral part of Ancelotti's squad, with 41 appearances in all competitions so far this season (19 starts), which is already more than the 33 (13 starts) he managed in 2020-21.
He has 12 goal involvements (four goals, eight assists) this season, up from nine last year (two goals, seven assists), and the youngster recently told Real Madrid's official website that he is looking forward to the test of City.
"They'll be tough opponents," he said. "We know the way they play and how good they are. If they've made it to the Champions League semi-finals, it means they're good, and it's down to the way City like to play, with a lot of possession.
"We're expecting a tough match and we have to make sure we keep playing like we have been and try to make it through."
Rodrygo might be under more pressure to perform given recent rumours that he may be one of the players who will have to make way for Mbappe should the club finally land the PSG star at the end of the season.
That being said, arguably Mbappe's best position is where Vinicius is currently doing his damage, which leads you to wonder if he too might be playing for his long-term future.
Of course, the Frenchman can play through the middle but there's another significant obstacle in the way there too in the form of his compatriot Benzema.
If Vinicius and Rodrygo want to make a case for maintaining their roles at the club, they have the perfect opportunity to do so by taking Madrid to a first Champions League final since 2018, and we will see just how ready for the challenge they are at the Etihad.