Andreas Christensen is expected to miss the final Clasico of the season after Barcelona confirmed he sustained a calf injury on international duty.

The centre-back started Denmark's opening Euro 2024 qualifier against Finland on Thursday but lasted only 18 minutes before being forced off.

Barcelona revealed it to be a problem with his left calf on Saturday following widespread media reports of him facing a period on the sidelines.

While the club have not given a timeframe for Christensen's return, simply saying he is "unavailable for selection and his recovery will determine his return", they are reportedly expecting him to be out for up to a month.

As such, he could miss as many as six games – among those, crucially, is the Copa del Rey semi-final second leg against Real Madrid on April 5, when Barca host Los Blancos having beaten them 1-0 at the Santiago Bernabeu in the first leg.

The other five matches he could be a doubt for are in LaLiga, though Barca will likely feel their 12-point lead at the summit is sufficient to cope without him for the time being.

Christensen has become a prominent figure at Camp Nou in recent times, however.

After joining on a free transfer from Chelsea in pre-season, the 26-year-old was initially a bit-part figure, making only five LaLiga appearances before the World Cup partly due to injury.

But he missed just one of their 10 games across all competitions prior to this international window – that being the first leg against Madrid.

Pedri plans to stay at Barcelona for "many years to come" but is not ruling out a move to the Premier League.

The 20-year-old has been a revelation since breaking into Barca's first team, establishing himself as a key player for the LaLiga leaders.

Pedri won FIFA's Golden Boy award for being the best young player in Europe in 2021 and quickly forced his way into the Spain team.

The young maestro is contracted to the Blaugrana until 2026 and has no intention of moving on for now, but suggested he may ply his trade overseas further down the line.

When asked about the possibility of a switch to England, he is quoted as saying by Marca: "At the moment, no. I'm at Barca and hopefully I'll stay here for many more years.

"I love LaLiga, but nothing should ever be ruled out."

Pedri will miss Spain's Euro 2024 qualifiers against Norway and Scotland due to a hamstring injury, but is relishing a new era for the national team under Luis de la Fuente.

Having played under De la Fuente at Under-21 level and in the Tokyo Olympics, Pedri believes the new Spain head coach will be a success.

Pedri said: "He is a person who goes straight ahead, he likes to work on the things he believes in and I think we will do well.

"All the coaches who come try to have the ball and play, especially because of the style of footballers we have, and I think not It will change a lot."

Julian Nagelsmann was sensationally sacked as Bayern Munich boss on Friday and replaced almost immediately by Thomas Tuchel.

The 35-year-old German had guided the Bavarians to last season's Bundesliga title.

And Bayern have looked good in reaching the Champions League quarter-finals this term.

Nagelsmann previously led RB Leipzig, guiding the side to the Champions League and the 2021 DFB-Pokal final, before moving to Bayern in 2021.

TOP STORY – SPURS MAKE MOVE FOR NAGELSMANN

Sky Sports claims Julian Nagelsmann is open to Tottenham's advances as they seek talks following his dismissal as Bayern Munich boss.

Spurs may be in the market for a new manager with uncertainty over Antonio Conte's future. Football Insider claims Nagelsmann is Spurs' number one priority if Conte departs.

Tottenham chairman Daniel Levy was also considering Nagelsmann in 2019 when he replaced Mauricio Pochettino with Jose Mourinho.

ROUND UP

- Liverpool, Arsenal, Chelsea and Tottenham are all circling for PSV midfielder Ibrahima Sangare, reports 90min. According to the report, the player's representatives have spoken to several Premier League clubs and he could be available for around £32million.

- Manchester United have joined the race for Chelsea midfielder Mateo Kovacic , who is being courted by Manchester City and Liverpool, according to Football.London.

- 90min claims Newcastle United have held talks with Marcus Thuram's representatives about a free agent move from Borussia Monchengladbach in the offseason. Thuram has already declared he will leave Gladbach when he contract expires at the end of the season, with Inter among a host of clubs interested.

- Chelsea are interested in signing ex-Leeds United man Raphinha from Barcelona, claims journalist Simon Phillips. The Blaugrana may be forced to sell players due to financial fair play regulations.

Barcelona's "doors are open" for Lionel Messi to return to the club, according to president Joan Laporta.

Messi joined Barca at the age of 13, going on to enjoy a hugely successful spell with the Catalan giants that saw him lift 10 LaLiga titles and win the Champions League on four occasions.

Barca's financial troubles meant Messi left the club in 2021, signing with French side Paris Saint-Germain on a two-year deal with the option to extend it for a third.

However, Messi is yet to agree to the extension and with his existing deal due to run out at the end of this season, there are rumours he could make a shock return to Camp Nou, with close friend and former team-mate Sergio Aguero rating the probability of Messi returning to Barca at "50 per cent".

Messi scored his 800th career goal with a stunning free-kick as Argentina returned to action after World Cup glory in Qatar with a 2-0 victory over Panama on Thursday.

Laporta says the seven-time Ballon d'Or winner is welcome to rejoin Barca, telling YouTube show The Business and Money Behind Sports: "Messi is the best player in history. He has been the most important player in the history of Barca.

"I have to be very careful with what I say. Messi is a PSG player and I have to have respect.

"Leo knows we have him in our hearts. He is part of our emblem. The legacy I found myself in when I became president was not good, and I had to make a decision that I'm not satisfied with. I have to find a way to improve Messi's current relationship with Barca.

"We'll see, but he knows that the doors of Barca are open."

Messi's Argentina are back in action on Tuesday against Curacao, when the 35-year-old will have the opportunity to score his 100th goal for La Albiceleste, having reached 99 with his historic strike against Panama.

Lionel Messi has a "50 per cent" chance of returning to Barcelona, according to former team-mate and close friend Sergio Aguero.

Messi left Barca for French side Paris Saint-Germain in 2021 after a long and decorated spell with the Catalan giants, winning 10 LaLiga titles and lifting the Champions League on four occasions.

His time in the French capital has been mixed, however, failing to deliver PSG's long-awaited first Champions League having been knocked out in the last 16 the last two seasons.

Messi scored his 800th career goal with a stunning free-kick as Argentina returned after World Cup glory in Qatar with a 2-0 victory over Panama on Thursday.

With the seven-time Ballon d'Or winner's contract at the Parc des Princes set to expire at the end of this campaign, Aguero feels a reunion with the club he first joined when he was 13 could be on the cards.

Aguero called upon Barca president Joan Laporta to bring Messi back to Camp Nou, telling Kings League's Twitch: "Laporta has to make an effort to bring Leo back.

"I think Leo should retire at Barca. Barcelona is his home, he has to finish his career here.

"My feeling is that there is a 50 per cent chance that he will return.

"I think if Laporta does that step [to contact Messi], everything will be much closer to happening."

Messi's Argentina are back in action on Tuesday against Curacao, when the 35-year-old will have the opportunity to score his 100th goal for La Albiceleste having moved on to 99 with his historic strike against Panama.

Bayern Munich have sensationally sacked Julian Nagelsmann, and Thomas Tuchel is in line to take over.

While not officially confirmed by the German club, widespread reports on Thursday suggested Nagelsmann had been dismissed.

Bayern sit second in the Bundesliga, one point behind Borussia Dortmund, and it is one of their rivals' former coaches who is favourite to replace Nagelsmann.

TOP STORY – TUCHEL SIGNS BAYERN DEAL

According to Fabrizio Romano, Tuchel – who was sacked by Chelsea in September – has already agreed to become Bayern's new coach.

Tuchel's first game would be against his former team Dortmund on April 1.

Bayern face Manchester City in the Champions League quarter-finals. Nagelsmann, meanwhile, is sure to be linked with plenty of high-profile job opportunities.

ROUND UP

- The Sun, citing a Sport Bild report, claim that Eintracht Frankfurt have placed an £88million (€99.7m) price tag on Manchester United target Randal Kolo Muani.

- The father of Brighton and Hove Albion's Alexis Mac Allister has informed ESPN no clubs are in concrete talks with his son, but that there are interested parties.

- According to 90min, Chelsea, Newcastle United and Manchester City are all scouting Juventus winger Samuel Iling-Junior.

- Fabrizio Romano says that Barcelona, Real Madrid and Liverpool are interested in Florian Wirtz, though Bayer Leverkusen are confident of keeping hold of the youngster.

Another week, another landmark for Lionel Messi as the Argentina superstar scored his 800th career goal in Thursday's friendly against Panama.

It's been an almighty journey for the all-time great, who has basically won everything on offer and claimed a record haul of seven Ballons d'Or along the way.

The player regarded by many as the greatest ever, Messi reached his latest milestone with a picture-perfect free kick in the 89th minute against Panama, curling one into the top corner after crashing two prior free kicks into the crossbar.

Although Messi hits new landmarks so frequently, at the age of 35 he is approaching a point where such achievements will become a little rarer.

With that in mind, it's worth celebrating Messi and his feats while we still can – therefore, Stats Perform has delved into the Opta data behind his latest accomplishment.

On the receiving end

It's nearly 18 years since Messi's first goal in professional football. Then a floppy-haired 17-year-old, he latched on to a Ronaldinho pass before lifting a clever lob over Albacete goalkeeper Raul Valbuena on May 1, 2005.

That goal has since become famous given its significance in marking the arrival of Messi – it also left a mark on the career of Valbuena.

"The press calls me every time he's broken a record or achieved something important, especially press from Catalonia," he told Marca nine years later. "To me, it's a funny anecdote in my career as a goalkeeper."

Well, it's all right for some. Many goalkeepers have had to contend with Messi smashing past them a few more times than Valbuena's single concession.

In total, 232 goalkeepers had let in a goal against Messi before Thursday. No one conceded more than Diego Alves, however, with the Brazilian beaten 21 times. Iker Casillas is a close second (19).

Returning the favour

Of course, over his career Messi has also become synonymous with creativity, routinely setting up goals for his team-mates.

But, given how many he's scored, he's also had to benefit from plenty of service from his colleagues as well – when he's not doing it all himself.

There are several players with whom he's struck up particularly effective on-pitch relationships.

For years, his combination with Dani Alves was unrivalled, the Brazilian setting up 42 of Messi's goals, but then along came Luis Suarez.

Suarez, Messi and Neymar were a revered and feared front three, their understanding on the pitch so deadly. The Uruguayan ended up assisting 47 goals for Messi across their six years together, with no one else teeing him up more often.

Messi also has his favourite clubs to score against. Impressively, Real Madrid (26) are right up there – but there are four teams he has punished more.

Athletic Bilbao (29), Valencia (31) and Atletico Madrid (32) all struggled against him, but if there has been one team who have resembled lambs to the slaughter when facing Messi, it's Sevilla (38).

Heights few have reached

The world of football numbers can be a little muddy. What constitutes an official goal? What's an official competition?

As such, there has been lots of confusion regarding the 'official' goals hauls of players down the years – we're looking at you, Pele and Romario.

The International Federation of Football History and Statistics (IFFHS) considers Cristiano Ronaldo to be the world record holder, stating in December 2021 that the Portugal forward was the first player to reach 800 official career goals.

This makes Messi the second to reach that figure, with Opta corroborating his career record. There remains a possibility he will eventually reach 1,000. No one is expecting him to get there soon, though.

After all, as good as he remains, achievements like scoring 91 times in a calendar year – as he managed in 2012 – appear to be beyond him these days.

That was his best ever year, which – perhaps unsurprisingly – coincided with his most prolific season (2011-12), when he scored 82 goals.

Still, the 35 goals he plundered in 2022 wasn't a bad return, especially given that haul included seven en route to World Cup success with Argentina.

Still to come?

There aren't many records at Barcelona that don't already belong to Messi. Top scorer? Done. Most appearances? Completed it. The most-photographed person at Camp Nou? Probably.

It seems unlikely Messi will be around at PSG long enough to have the same kind of impact there, but he certainly still has career targets in sight.

There's the aforementioned 1,000 goals landmark, though before then he will have his eyes on more international achievements.

Messi's free kick to seal Thursday's 2-0 win left him just one from reaching 100 with Argentina, and after that he'll perhaps have designs on usurping both Ali Daei (109) and Ronaldo (120), the two highest-scoring players in men's international football.

Similarly, with Ronaldo now out of the way in Saudi Arabia, Messi could also take his record for the most Champions League goals (140) – Messi is on 129.

But regardless of what else he does or doesn't go on to achieve, Thursday's milestone is just another reminder of how fortunate we've been to witness Messi's truly remarkable career.

Lionel Messi reached the latest major milestone of his storied career on Thursday as he moved on to 800 goals with a stunning free kick for to seal Argentina's 2-0 friendly win against Panama on Thursday.

The reigning World Cup champions returned to Buenos Aires where they received a thunderous reception from their loyal supporters, but they would have to wait until the final moments for their favourite son to get on the scoresheet.

Messi had hit the crossbar with a free kick in the first half, and after a second free kick was saved by inspired Panama goalkeeper Jose Guerra, he struck the woodwork again with a third free kick, although this one led to the opening goal as Thiago Almada tapped in the rebound.

But his fourth free kick finally curled under the bar and into the top-right corner, sending the stadium into raptures.

Of course, it was not so long ago that Messi hit another goals landmark.

His tap-in from Kylian Mbappe's inch-perfect cross against Marseille on February 26 was the 700th club goal of Messi's career – the strike against Panama was only his second for club or country since then.

Messi's stunner at El Monumental on Thursday was his 99th on the international stage.

Only his old nemesis Cristiano Ronaldo (120) and Iran legend Ali Daei (109) have scored more goals in international men's football than Messi, who looks set to continue playing for Argentina for a little while yet.

As such, his 100th goal for the Albiceleste is seemingly just around the corner.

But much like with that international milestone, Messi is not the first player to reach 800 across a full career.

Data can get a little murkier when you go deep into the past, with historical inconsistencies making it a little tricky to classify "official goals" or "official competitions".

The likes of Brazilian greats Romario and Pele are among a group of players deemed by some to have scored over 1,000 goals over their careers, but many of those were netted in friendlies or "unofficial" games.

The International Federation of Football History and Statistics (IFFHS) considered Cristiano Ronaldo to be the first player to ever reach 800 official goals in December 2021.

With that in mind, Thursday's goal makes Messi the second to reach the landmark, and he is still going strong.

He has scored 18 for the season (all competitions) with PSG, though he also netted seven in as many games at Qatar 2022 as Argentina won the World Cup.

Of course, the vast majority of his 800 goals have been scored in the colours of Barcelona.

During 17 years with Barca's first team, Messi scored 672 times. That is 440 more than any other player in the club's history, while he also holds their record for most appearances (778).

And with his future at PSG in doubt, he could yet extend those records at Camp Nou.

Patrick Kluivert has urged Barcelona to sign either Goncalo Ramos or Roberto Firmino at the end of the season.

Barca are on course to be crowned LaLiga champions after a big recruitment drive that saw them bring in the likes of Robert Lewandowski and Raphinha.

Lewandowski has scored 25 goals in his first season with the Blaugrana, leading the line superbly and demonstrating the sort of clinical finishing that has made him one of the best strikers in the world.

Former Barca striker Kluivert wants the Catalan giants to add more firepower by landing Benfica striker Ramos or long-serving Liverpool frontman Firmino, who will leave Anfield when his contract expires at the end of the season.

The ex-Netherlands international told the Barca Blaugranes portal: "Financial Fair Play is something you have to take into account, but who is on my wish list? It definitely has to be a striker.

"Because after Lewandowski you need to have a centre-forward. I like Goncalo Ramos a lot. I like that one player and he has done a very good job for the Portugal team and also at Benfica.

"I think Firmino would also be a very interesting player in Barcelona. A striker is what is needed to strengthen Barcelona. The rest would be fine if everyone stayed."

LaLiga filed an eighth complaint regarding racist abuse directed at Real Madrid forward Vinicius Junior following incidents in Sunday's clash with Barcelona.

The hosts secured a 2-1 Clasico win at Camp Nou following Franck Kessie's 92nd-minute strike, which opened a 12-point lead for Xavi's side over Madrid.

That victory has been marred by racist abuse towards Vinicius, however, with LaLiga confirming a complaint had been lodged to the Barcelona Court of Instruction.

A statement read: "In view of the events that took place at the FC Barcelona-Real Madrid match, in which intolerable racist behaviour was once again observed against Vinicius Jr, LaLiga has reported the racist insults to the Barcelona Court of Instruction.

"This is the eighth complaint filed by LaLiga with the corresponding authorities for racist abuse against Vinicius Jr."

Earlier this week, Mallorca announced a fan's membership had been revoked for three years after racist abuse was directed at Vinicius and Villarreal's Samuel Chukwueze.

In February, Real Valladolid suspended 12 season ticket holders for abusing Vinicius during a league match two months earlier.

UEFA has appointed ethics and disciplinary inspectors to investigate allegations that Barcelona made payments to a company owned by a former top referee.

A corruption complaint was recently filed by Spanish prosecutors against the Catalan giants, concerning payments allegedly made to a business run by Jose Maria Enriquez Negreira, once a top match official and latterly vice-president of Spain's Technical Committee of Referees (CTA).

It has been claimed the total payments from Barcelona exceeded €7million, dating from 2001 to 2018.

Newspaper El Pais last month reported Negreira's company – DASNIL 95 SL – produced written reports and DVD assessments of referees for Barcelona prior to games.

UEFA announced in a statement on Thursday that it has opened an investigation into the matter.

"In accordance with Article 31(4) of the UEFA Disciplinary Regulations, UEFA Ethics and Disciplinary Inspectors have today been appointed to conduct an investigation regarding a potential violation of UEFA's legal framework by FC Barcelona in connection with the so-called 'Caso Negreira'," the statement read, adding that: "Further information regarding this matter will be made available in due course."

Barcelona president Joan Laporta maintains the club has done nothing wrong and that the allegations are simply an attempt to derail the LaLiga leaders.

Laporta recently said: "The campaign we are suffering is not by chance, you all know this. Its objective is, in the short term, to destabilise the team, and in the medium term, to control Barca. I will have time and I want to explain to you who, why and how they want to orchestrate this campaign.

"Have no doubt that we will defend ourselves. And we will not only defend ourselves, we will attack."

Bojan Krkic announced his retirement on Thursday and picked out having to leave Barcelona for Stoke City as one of the toughest moments of his career.

The Catalan forward, who had his thunder stolen by Gerard Pique letting slip his retirement plans earlier in the week, has elected to hang up his boots at the age of 32.

Bojan left Vissel Kobe at the start of the year after several nomadic seasons that followed the end of his second spell at Barcelona.

He began his career at Barcelona and had two years in Italy with Roma and Milan before returning to Camp Nou in 2013 and being immediately loaned to Ajax.

Hopes of sustaining his Barcelona career were extinguished when he was sold to Premier League side Stoke in July 2014.

Former Stoke manager Mark Hughes and centre-back Ryan Shawcross were among those who sent tributes to Bojan, which were played at his retirement press conference, along with messages from Rafael Nadal, Thierry Henry, Andres Iniesta, Pique, Patrick Kluivert and Xavi.

Looking at the highs and lows of his career, Bojan said: "The most gratifying part was the first night at Camp Nou, the first goal, entering the professional world.

"There have been several toughest moments. When I signed for Stoke City it was tough, because I cut the umbilical cord that attached me to the club."

Bojan scored 41 goals in 166 official games for Barcelona, making his debut under Frank Rijkaard in September 2017 and scoring in the Champions League and LaLiga as a 17-year-old.

He was a hot prospect at that age who never developed into the world beater many thought he would become, despite playing under coaches including Pep Guardiola and Massimiliano Allegri.

At Stoke, he scored seven goals in his second Premier League season, his best return for the Potters.

After joining Stoke, he had loans at Mainz and Alaves, before heading to MLS side CF Montreal and finishing his playing days with Vissel Kobe in Japan.

"All the coaches make a mark on you. But the most, Frank Rijkaard," Bojan said. "He gave me the opportunity and continuity to back myself. Without him, my career would not have been possible."

He is planning to take coaching badges and stay in football, saying it would make him "very happy" if an opportunity at Barcelona ever came up.

There will be one final match for Bojan, a farewell game for the Catalan regional team.

"The federation is working to find a match at the beginning of June," he said.

Chelsea seem to have resigned themselves to making a major loss on Romelu Lukaku, who has only netted five times on loan at Inter this term.

According to a Football Insider report, the Blues are ready to move him on in at the end of the season, with Inter unlikely to try to extend his stay in Milan.

Chelsea spent £97.5milion to bring Lukaku back to Stamford Bridge in August 2021, but they are unlikely to get anywhere near that now.

TOP STORY – GERMAN CHAMPIONS LINE UP SHOCK LUKAKU MOVE

Bayern Munich are lining up a shock move for Chelsea's Romelu Lukaku to bolster their attacking options, claims Fichajes.

The report claims Bayern boss Julian Nagelsmann is an admirer of the Belgium striker, who he believes is one of the world's best forwards if injury free.

Bayern will not commence negotiations with Chelsea until the end of the season. The German champions had been linked with Harry Kane as they look for someone to replace Robert Lewandowski, who left for Barcelona last year.

Calciomercato reports that Chelsea may try to land a deal with Roma with a swap deal involving Tammy Abraham.

ROUND-UP

– 90min claims Manchester City have reignited their interest in signing 19-year-old Bayer Leverkusen midfielder Florian Wirtz following a long-term knee injury which forced him to miss the 2022 World Cup. Fabrizio Romano claims Real Madrid will compete for the German's services too.

– Tottenham are interested in Manchester United goalkeeper Dean Henderson, reports ESPN. Henderson is currently on loan at Nottingham Forest from United, who could use Spurs' interest as leverage in a deal for Harry Kane, per the report

– Leeds United forward Wilfried Gnonto is drawing interest from Arsenal, Chelsea and Manchester City, according to Gazzetta dello Sport, while 90min claims Juventus and Napoli are among a list of Italian clubs tracking him too.

– Fabrizio Romano claims Barcelona on the cusp of agreeing to a deal with Athletic Bilbao centre-back Inigo Martinez to join the Blaugrana on a free transfer in the off-season.

– Paris Saint-Germain are prepared to let Portuguese midfielder Renato Sanches exit amid interest from Milan along with Premier League clubs Aston Villa, Liverpool, Newcastle United, Tottenham and Wolves, reports 90min.

– Football London reports Arsenal are ready to ramp up their interest in Real Sociedad midfielder Martin Zubimendi with a bid to come in the coming months, although he has a €60m release clause in his contract.

Napoli striker Victor Osimhen is garnering a lot of interest, sitting clear at the top of the Serie A scoring charts this term with 21 goals.

The 24-year-old Nigerian striker is contracted with the runaway Serie A leaders until 2025.

While they would love to retain his services long-term, the breakout star hinted that may not be in the cards after recently showing interest in a move to the Premier League.

TOP STORY – NAPOLI PLACE BUMPER PRICE TAG ON OSIMHEN

Foot Mercato reports Napoli have placed a €150million price tag on Osimhen, amid new interest from French powerhouse Paris Saint-Germain.

PSG have entered to race for the Nigerian, with Manchester United and Chelsea both reportedly chasing his signature in the off-season.

But Napoli have moved to protect their prize asset and will not entertain a lower price.

ROUND-UP

– However, Relevo claims PSG's off-season priority signing is Manchester City midfielder Bernardo Silva. The Portuguese is reportedly keen for a new challenge, although he is contracted until 2025 and City asked for £80m (€90m) for him last off-season.

– Manchester United are ramping up their interest in Monaco centre-back Alex Disasi, claims The Mail. The Frenchman is rated at £44m (€50m), with United boss Erik ten Hag keen to bolster his defensive ranks in the next transfer window with uncertainty over the futures of Harry Maguire and Victor Lindelof.

– Football Insider claims Liverpool have not been deterred by Borussia Dortmund's reported €150m demand for Jude Bellingham. The Reds are determined to land the English midfielder amid interest from Real Madrid, Manchester City, Chelsea and Manchester United.

– Sport claims Chelsea may release Pierre-Emerick Aubameyang from his contract after the season, with Mundo Deportivo reporting he is set to return to Barcelona as a low-cost option.

– Unnamed Saudi Arabian and Qatari clubs are interested in Luka Modric,  but the veteran Croatian midfielder remains in talks with Real Madrid on a new deal, according to Sky Sports Germany.

– Barcelona's veteran full-back Jordi Alba could have his contracted terminated in the off-season as the Blaugrana looks to trim their wage bill and focus on new signings, reports Sport.

Ronald Araujo has withdrawn from the Uruguay squad for their two upcoming friendlies after suffering a thigh injury during Barcelona's win over Real Madrid on Sunday.

The defender was able to complete a dramatic 2-1 El Clasico victory for the Blaugrana at Camp Nou, but he will not face Japan on Friday or South Korea next Tuesday.

Barca revealed Araujo underwent tests on Monday and discovered he has done damage to his left adductor.

The 24-year-old scored an own goal to put Madrid in front, but Sergi Roberto equalised just before half-time and Franck Kessie's late winner put Xavi's side 12 points clear of their fierce rival at the top of LaLiga.

Uruguay will also be without attacking midfielder Giorgian de Arrascaeta.

Diego Hernandez and Sebastian Caceres have been called up as replacements by interim coach Marcelo Broli.